메뉴 건너뛰기




Volumn 6, Issue 2, 2010, Pages 88-101

Invariant natural killer t cell-based therapy of autoimmune diseases

Author keywords

galactosylceramide; Autoimmunity; Cd1d; Glycolipids; Immunomodulation; Invariant natural killer t cells

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN;

EID: 77952520597     PISSN: 15733955     EISSN: None     Source Type: Journal    
DOI: 10.2174/157339510791111682     Document Type: Article
Times cited : (3)

References (184)
  • 1
    • 0023267519 scopus 로고
    • Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes
    • Budd RC, Miescher GC, Howe RC, Lees RK, Bron C, MacDonald HR. Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes. J Exp Med 1987; 166: 577-82.
    • (1987) J Exp Med , vol.166 , pp. 577-582
    • Budd, R.C.1    Miescher, G.C.2    Howe, R.C.3    Lees, R.K.4    Bron, C.5    Macdonald, H.R.6
  • 2
    • 0023192930 scopus 로고
    • A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family
    • Fowlkes BJ, Kruisbeek AM, Ton-That H, et al. A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family. Nature 1987; 329: 251-4.
    • (1987) Nature , vol.329 , pp. 251-254
    • Fowlkes, B.J.1    Kruisbeek, A.M.2    Ton-That, H.3
  • 3
    • 0023464195 scopus 로고
    • Phenotypic properties, interleukin 2 production, and developmental origin of a mature subpopulation of Lyt-2- L3T4- mouse thymocytes
    • Ceredig R, Lynch F, Newman P. Phenotypic properties, interleukin 2 production, and developmental origin of a mature subpopulation of Lyt-2- L3T4- mouse thymocytes. Proc Natl Acad Sci USA 1987; 84: 8578-82.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8578-8582
    • Ceredig, R.1    Lynch, F.2    Newman, P.3
  • 5
    • 0029032639 scopus 로고
    • Predominant expression of invariant V alpha 14+ TCR alpha chain in NK1.1+ T cell populations
    • Makino Y, Kanno R, Ito T, Higashino K, Taniguchi M. Predominant expression of invariant V alpha 14+ TCR alpha chain in NK1.1+ T cell populations. Int Immunol 1995; 7: 1157-61.
    • (1995) Int Immunol , vol.7 , pp. 1157-1161
    • Makino, Y.1    Kanno, R.2    Ito, T.3    Higashino, K.4    Taniguchi, M.5
  • 7
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR- mediated activation of valpha14 NKT cells by glycosylceramides
    • Kawano T, Cui J, Koezuka Y, et al. CD1d-restricted and TCR- mediated activation of valpha14 NKT cells by glycosylceramides. Science 1997; 278: 1626-9.
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1    Cui, J.2    Koezuka, Y.3
  • 8
    • 11244304412 scopus 로고    scopus 로고
    • Alpha-Galactosylceramide therapy for autoimmune diseases: Prospects and obstacles
    • Van Kaer L. Alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles. Nat Rev Immunol 2005; 5: 31-42.
    • (2005) Nat Rev Immunol , vol.5 , pp. 31-42
    • van Kaer, L.1
  • 9
    • 36448952375 scopus 로고    scopus 로고
    • CD1 antigen presentation: How it works
    • Barral D, Brenner M. CD1 antigen presentation: how it works. Nat Rev Immunol 2007 2007; 7: 929-41.
    • (2007) Nat Rev Immunol , vol.2007 , Issue.7 , pp. 929-941
    • Barral, D.1    Brenner, M.2
  • 10
    • 34247577500 scopus 로고    scopus 로고
    • NKT cells: T lymphocytes with innate effector functions
    • Van Kaer L. NKT cells: T lymphocytes with innate effector functions. Curr Opin Immunol 2007; 19: 354-64.
    • (2007) Curr Opin Immunol , vol.19 , pp. 354-364
    • van Kaer, L.N.K.T.1
  • 11
    • 10044286529 scopus 로고    scopus 로고
    • Going both ways: Immune regulation via CD1d-dependent NKT cells
    • Godfrey DI, Kronenberg M. Going both ways: immune regulation via CD1d-dependent NKT cells. J Clin Invest 2004; 114: 1379-88.
    • (2004) J Clin Invest , vol.114 , pp. 1379-1388
    • Godfrey, D.I.1    Kronenberg, M.2
  • 12
    • 0033521624 scopus 로고    scopus 로고
    • Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments
    • Chiu YH, Jayawardena J, Weiss A, et al. Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J Exp Med 1999; 189: 103-10.
    • (1999) J Exp Med , vol.189 , pp. 103-110
    • Chiu, Y.H.1    Jayawardena, J.2    Weiss, A.3
  • 14
    • 1842682026 scopus 로고    scopus 로고
    • Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide
    • Jahng A, Maricic I, Aguilera C, Cardell S, Halder R, Kumar V. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J Exp Med 2004; 199: 947-57.
    • (2004) J Exp Med , vol.199 , pp. 947-957
    • Jahng, A.1    Maricic, I.2    Aguilera, C.3    Cardell, S.4    Halder, R.5    Kumar, V.6
  • 15
    • 34250849637 scopus 로고    scopus 로고
    • Control points in NKT-cell development
    • Godfrey DI, Berzins SP. Control points in NKT-cell development. Nat Rev Immunol 2007; 7: 505-18.
    • (2007) Nat Rev Immunol , vol.7 , pp. 505-518
    • Godfrey, D.I.1    Berzins, S.P.2
  • 16
    • 64649090333 scopus 로고    scopus 로고
    • NKT cells: From totipotency to regenerative medicine
    • Wakao H. NKT cells: from totipotency to regenerative medicine. Arch Immunol Ther Exp (Warsz); 57: 117-28.
    • Arch Immunol Ther Exp (Warsz) , vol.57 , pp. 117-128
    • Wakao, H.1
  • 18
    • 22944442645 scopus 로고    scopus 로고
    • Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes
    • Wei DG, Lee H, Park SH, et al. Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med 2005; 202: 239-48.
    • (2005) J Exp Med , vol.202 , pp. 239-248
    • Wei, D.G.1    Lee, H.2    Park, S.H.3
  • 19
    • 0037452710 scopus 로고    scopus 로고
    • Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency
    • Stanic A, De Silva A, Park J, et al. Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency. Proc Natl Acad Sci USA 2003; 100: 1849-54.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1849-1854
    • Stanic, A.1    de Silva, A.2    Park, J.3
  • 20
    • 34247592222 scopus 로고    scopus 로고
    • Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
    • Porubsky S, Speak AO, Luckow B, Cerundolo V, Platt FM, Gröne HJ. Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency. Proc Natl Acad Sci USA 2007; 104: 5977-82.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5977-5982
    • Porubsky, S.1    Speak, A.O.2    Luckow, B.3    Cerundolo, V.4    Platt, F.M.5    Gröne, H.J.6
  • 21
    • 60749112787 scopus 로고    scopus 로고
    • The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells
    • Lazarevic V, Zullo AJ, Schweitzer MN, et al. The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nat Immunol 2009; 10: 306-13.
    • (2009) Nat Immunol , vol.10 , pp. 306-313
    • Lazarevic, V.1    Zullo, A.J.2    Schweitzer, M.N.3
  • 22
    • 58149099175 scopus 로고    scopus 로고
    • SLAM receptors and SAP influence lymphocyte interactions, development and function
    • Schwartzberg PL, Mueller KL, Qi H, Cannons JL. SLAM receptors and SAP influence lymphocyte interactions, development and function. Nat Rev Immunol 2009; 9: 39-46.
    • (2009) Nat Rev Immunol , vol.9 , pp. 39-46
    • Schwartzberg, P.L.1    Mueller, K.L.2    Qi, H.3    Cannons, J.L.4
  • 23
    • 20144387328 scopus 로고    scopus 로고
    • Regulation of NKT cell development by SAP, the protein defective in XLP
    • Nichols KE, Hom J, Gong SY, et al. Regulation of NKT cell development by SAP, the protein defective in XLP. Nat Med 2005; 11: 340-5.
    • (2005) Nat Med , vol.11 , pp. 340-345
    • Nichols, K.E.1    Hom, J.2    Gong, S.Y.3
  • 24
    • 15444374149 scopus 로고    scopus 로고
    • Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product
    • Pasquier B, Yin L, Fondaneche MC, et al. Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product. J Exp Med 2005; 201: 695-701.
    • (2005) J Exp Med , vol.201 , pp. 695-701
    • Pasquier, B.1    Yin, L.2    Fondaneche, M.C.3
  • 25
    • 14844339362 scopus 로고    scopus 로고
    • Signaling lymphocytic activation molecule-associated protein controls NKT cell functions
    • Chung B, Aoukaty A, Dutz J, Terhorst C, Tan R. Signaling lymphocytic activation molecule-associated protein controls NKT cell functions. J Immunol 2005; 174: 3153-7.
    • (2005) J Immunol , vol.174 , pp. 3153-3157
    • Chung, B.1    Aoukaty, A.2    Dutz, J.3    Terhorst, C.4    Tan, R.5
  • 26
    • 0032853934 scopus 로고    scopus 로고
    • Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice
    • Eberl G, Lowin-Kropf B, MacDonald HR. Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice. J Immunol 1999; 163: 4091-4.
    • (1999) J Immunol , vol.163 , pp. 4091-4094
    • Eberl, G.1    Lowin-Kropf, B.2    Macdonald, H.R.3
  • 27
    • 0032723181 scopus 로고    scopus 로고
    • The Src family tyrosine kinase Fyn regulates natural killer T cell development
    • Gadue P, Morton N, Stein PL. The Src family tyrosine kinase Fyn regulates natural killer T cell development. J Exp Med 1999; 190: 1189-96.
    • (1999) J Exp Med , vol.190 , pp. 1189-1196
    • Gadue, P.1    Morton, N.2    Stein, P.L.3
  • 28
    • 36049012716 scopus 로고    scopus 로고
    • Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development
    • Griewank K, Borowski C, Rietdijk S, et al. Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 2007; 27: 751-62.
    • (2007) Immunity , vol.27 , pp. 751-762
    • Griewank, K.1    Borowski, C.2    Rietdijk, S.3
  • 29
    • 65249162405 scopus 로고    scopus 로고
    • Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development
    • Mycko MP, Ferrero I, Wilson A, et al. Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development. J Immunol 2009; 182: 4641-8.
    • (2009) J Immunol , vol.182 , pp. 4641-4648
    • Mycko, M.P.1    Ferrero, I.2    Wilson, A.3
  • 30
    • 61449190767 scopus 로고    scopus 로고
    • WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function
    • Westerberg LS, de la Fuente MA, Wermeling F, et al. WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function. Blood 2008; 112: 4139-47.
    • (2008) Blood , vol.112 , pp. 4139-4147
    • Westerberg, L.S.1    de la Fuente, M.A.2    Wermeling, F.3
  • 31
    • 65549150035 scopus 로고    scopus 로고
    • The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function
    • Locci M, Draghici E, Marangoni F, et al. The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function. J Exp Med 2009; 206: 735-42.
    • (2009) J Exp Med , vol.206 , pp. 735-742
    • Locci, M.1    Draghici, E.2    Marangoni, F.3
  • 32
    • 51349121407 scopus 로고    scopus 로고
    • The transcription factor PLZF directs the effector program of the NKT cell lineage
    • Savage AK, Constantinides MG, Han J, et al. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 2008; 29: 391-403.
    • (2008) Immunity , vol.29 , pp. 391-403
    • Savage, A.K.1    Constantinides, M.G.2    Han, J.3
  • 33
    • 50049084627 scopus 로고    scopus 로고
    • The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions
    • Kovalovsky D, Uche OU, Eladad S, et al. The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat Immunol 2008; 9: 1055-64.
    • (2008) Nat Immunol , vol.9 , pp. 1055-1064
    • Kovalovsky, D.1    Uche, O.U.2    Eladad, S.3
  • 34
    • 50049093377 scopus 로고    scopus 로고
    • The making of NKT cells
    • Gapin L. The making of NKT cells. Nat Immunol 2008; 9: 1009-11.
    • (2008) Nat Immunol , vol.9 , pp. 1009-1011
    • Gapin, L.1
  • 36
    • 65649111531 scopus 로고    scopus 로고
    • Invariant natural killer T cells: Innate-like T cells with potent immunomodulatory activities
    • Wu L, Gabriel CL, Parekh VV, Van Kaer L. Invariant natural killer T cells: innate-like T cells with potent immunomodulatory activities. Tissue Antigens 2009; 73(6): 535-45
    • (2009) Tissue Antigens , vol.73 , Issue.6 , pp. 535-545
    • Wu, L.1    Gabriel, C.L.2    Parekh, V.V.3    van Kaer, L.4
  • 37
    • 0037290833 scopus 로고    scopus 로고
    • CD1-restricted antigen presentation: An oily matter
    • Joyce S, Van Kaer L. CD1-restricted antigen presentation: an oily matter. Curr Opin Immunol 2003; 15: 95-104.
    • (2003) Curr Opin Immunol , vol.15 , pp. 95-104
    • Joyce, S.1    van Kaer, L.2
  • 38
    • 0037160108 scopus 로고    scopus 로고
    • Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain
    • Kang SJ, Cresswell P. Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain. J Biol Chem 2002; 277: 44838-44.
    • (2002) J Biol Chem , vol.277 , pp. 44838-44844
    • Kang, S.J.1    Cresswell, P.2
  • 39
    • 0347776209 scopus 로고    scopus 로고
    • Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
    • Brigl M, Bry L, Kent SC, Gumperz JE, Brenner MB. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat Immunol 2003; 4: 1230-7.
    • (2003) Nat Immunol , vol.4 , pp. 1230-1237
    • Brigl, M.1    Bry, L.2    Kent, S.C.3    Gumperz, J.E.4    Brenner, M.B.5
  • 40
    • 20144389877 scopus 로고    scopus 로고
    • Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
    • Mattner J, Debord K, Ismail N, et al. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005; 434: 525-9.
    • (2005) Nature , vol.434 , pp. 525-529
    • Mattner, J.1    Debord, K.2    Ismail, N.3
  • 41
    • 33847361128 scopus 로고    scopus 로고
    • Invariant NKT cells amplify the innate immune response to lipopolysaccharide
    • Nagarajan NA, Kronenberg M. Invariant NKT cells amplify the innate immune response to lipopolysaccharide. J Immunol 2007; 178: 2706-13.
    • (2007) J Immunol , vol.178 , pp. 2706-2713
    • Nagarajan, N.A.1    Kronenberg, M.2
  • 42
    • 24744459852 scopus 로고    scopus 로고
    • Interplay of cytokines and microbial signals in regulation of CD1d expression and NKT cell activation
    • Sköld M, Xiong X, Illarionov P, Besra G, Behar S. Interplay of cytokines and microbial signals in regulation of CD1d expression and NKT cell activation. J Immunol 2005; 175: 3584-93.
    • (2005) J Immunol , vol.175 , pp. 3584-3593
    • Sköld, M.1    Xiong, X.2    Illarionov, P.3    Besra, G.4    Behar, S.5
  • 43
    • 34447131000 scopus 로고    scopus 로고
    • CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor
    • Borg NA, Wun KS, Kjer-Nielsen L, et al. CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 2007; 448: 44-9.
    • (2007) Nature , vol.448 , pp. 44-49
    • Borg, N.A.1    Wun, K.S.2    Kjer-Nielsen, L.3
  • 44
    • 3042767903 scopus 로고    scopus 로고
    • Natural killer T cells as targets for immunotherapy of autoimmune diseases
    • Van Kaer L. Natural killer T cells as targets for immunotherapy of autoimmune diseases. Immunol Cell Biol 2004; 82: 315-22.
    • (2004) Immunol Cell Biol , vol.82 , pp. 315-322
    • van Kaer, L.1
  • 45
    • 0141814650 scopus 로고    scopus 로고
    • The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion
    • Wilson M, Johansson C, Olivares-Villagómez D, et al. The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion. Proc Natl Acad Sci USA 2003; 100: 10913-8.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10913-10918
    • Wilson, M.1    Johansson, C.2    Olivares-Villagómez, D.3
  • 46
    • 24644433401 scopus 로고    scopus 로고
    • Glycolipid antigen induces long-term natural killer T cell anergy in mice
    • Parekh V, Wilson M, Olivares-Villagómez D, et al. Glycolipid antigen induces long-term natural killer T cell anergy in mice. J Clin Invest 2005; 115: 2572-83.
    • (2005) J Clin Invest , vol.115 , pp. 2572-2583
    • Parekh, V.1    Wilson, M.2    Olivares-Villagómez, D.3
  • 48
    • 17044412178 scopus 로고    scopus 로고
    • Distinct roles of dendritic cells and B cells in Va14Ja18 natural T cell activation in vivo
    • Bezbradica JS, Stanic AK, Matsuki N, et al. Distinct roles of dendritic cells and B cells in Va14Ja18 natural T cell activation in vivo. J Immunol 2005; 174: 4696-705.
    • (2005) J Immunol , vol.174 , pp. 4696-4705
    • Bezbradica, J.S.1    Stanic, A.K.2    Matsuki, N.3
  • 49
    • 12844285609 scopus 로고    scopus 로고
    • Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion
    • Schmieg J, Yang G, Franck RW, Van Rooijen N, Tsuji M. Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion. Proc Natl Acad Sci USA 2005; 102: 1127-32.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1127-1132
    • Schmieg, J.1    Yang, G.2    Franck, R.W.3    van Rooijen, N.4    Tsuji, M.5
  • 50
    • 45749092102 scopus 로고    scopus 로고
    • Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice
    • Kim S, Lalani S, Parekh VV, Vincent TL, Wu L, Van Kaer L. Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice. J Clin Invest 2008; 118: 2301-15.
    • (2008) J Clin Invest , vol.118 , pp. 2301-2315
    • Kim, S.1    Lalani, S.2    Parekh, V.V.3    Vincent, T.L.4    Wu, L.5    van Kaer, L.6
  • 51
    • 57149119510 scopus 로고    scopus 로고
    • Bacterial infection alters the kinetics and function of iNKT cell responses
    • Choi HJ, Xu H, Geng Y, Colmone A, Cho H, Wang CR. Bacterial infection alters the kinetics and function of iNKT cell responses. J Leukoc Biol 2008; 84: 1462-71.
    • (2008) J Leukoc Biol , vol.84 , pp. 1462-1471
    • Choi, H.J.1    Xu, H.2    Geng, Y.3    Colmone, A.4    Cho, H.5    Wang, C.R.6
  • 52
    • 53149100521 scopus 로고    scopus 로고
    • Rapid NKT cell responses are self-terminating during the course of microbial infection
    • Chiba A, Dascher CC, Besra GS, Brenner MB. Rapid NKT cell responses are self-terminating during the course of microbial infection. J Immunol 2008; 181: 2292-302.
    • (2008) J Immunol , vol.181 , pp. 2292-2302
    • Chiba, A.1    Dascher, C.C.2    Besra, G.S.3    Brenner, M.B.4
  • 53
    • 58149189061 scopus 로고    scopus 로고
    • Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy
    • Chang WS, Kim JY, Kim YJ, et al. Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy. J Immunol 2008; 181: 6707-10.
    • (2008) J Immunol , vol.181 , pp. 6707-6710
    • Chang, W.S.1    Kim, J.Y.2    Kim, Y.J.3
  • 54
    • 64849116017 scopus 로고    scopus 로고
    • PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells
    • Parekh VV, Lalani S, Kim S, et al. PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells. J Immunol 2009; 182: 2816-26.
    • (2009) J Immunol , vol.182 , pp. 2816-2826
    • Parekh, V.V.1    Lalani, S.2    Kim, S.3
  • 55
    • 67449158878 scopus 로고    scopus 로고
    • Cutting edge: CD28 engagement releases antigen-activated invariant NKT cells from the inhibitory effects of PD-1
    • Wang J, Cheng L, Wondimu Z, Swain M, Santamaria P, Yang Y. Cutting edge: CD28 engagement releases antigen-activated invariant NKT cells from the inhibitory effects of PD-1. J Immunol 2009; 182: 6644-7.
    • (2009) J Immunol , vol.182 , pp. 6644-6647
    • Wang, J.1    Cheng, L.2    Wondimu, Z.3    Swain, M.4    Santamaria, P.5    Yang, Y.6
  • 56
    • 45549088950 scopus 로고    scopus 로고
    • Cutting edge: Nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells
    • Silk JD, Salio M, Reddy BG, et al. Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells. J Immunol 2008; 180: 6452-6.
    • (2008) J Immunol , vol.180 , pp. 6452-6456
    • Silk, J.D.1    Salio, M.2    Reddy, B.G.3
  • 57
    • 27744562232 scopus 로고    scopus 로고
    • Differential antitumor immunity mediated by NKT cell subsets in vivo
    • Crowe NY, Coquet JM, Berzins SP, et al. Differential antitumor immunity mediated by NKT cell subsets in vivo. J Exp Med 2005; 202: 1279-88.
    • (2005) J Exp Med , vol.202 , pp. 1279-1288
    • Crowe, N.Y.1    Coquet, J.M.2    Berzins, S.P.3
  • 58
    • 0037018108 scopus 로고    scopus 로고
    • Distinct functional lineages of human V(alpha)24 natural killer T cells
    • Lee PT, Benlagha K, Teyton L, Bendelac A. Distinct functional lineages of human V(alpha)24 natural killer T cells. J Exp Med 2002; 195: 637-41.
    • (2002) J Exp Med , vol.195 , pp. 637-641
    • Lee, P.T.1    Benlagha, K.2    Teyton, L.3    Bendelac, A.4
  • 59
    • 0037018101 scopus 로고    scopus 로고
    • Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining
    • Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med 2002; 195: 625-36.
    • (2002) J Exp Med , vol.195 , pp. 625-636
    • Gumperz, J.E.1    Miyake, S.2    Yamamura, T.3    Brenner, M.B.4
  • 60
    • 49649123906 scopus 로고    scopus 로고
    • Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population
    • Coquet JM, Chakravarti S, Kyparissoudis K, et al. Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population. Proc Natl Acad Sci USA 2008; 105: 11287-92.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11287-11292
    • Coquet, J.M.1    Chakravarti, S.2    Kyparissoudis, K.3
  • 61
    • 34249059942 scopus 로고    scopus 로고
    • Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia
    • Michel ML, Keller AC, Paget C, et al. Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. J Exp Med 2007; 204: 995-1001.
    • (2007) J Exp Med , vol.204 , pp. 995-1001
    • Michel, M.L.1    Keller, A.C.2    Paget, C.3
  • 62
    • 41549135632 scopus 로고    scopus 로고
    • The biological functions of T helper 17 cell effector cytokines in inflammation
    • Ouyang W, Kolls JK, Zheng Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 2008; 28: 454-67.
    • (2008) Immunity , vol.28 , pp. 454-467
    • Ouyang, W.1    Kolls, J.K.2    Zheng, Y.3
  • 63
    • 65549114070 scopus 로고    scopus 로고
    • Invariant NKT cells inhibit development of the Th17 lineage
    • Mars LT, Araujo L, Kerschen P, et al. Invariant NKT cells inhibit development of the Th17 lineage. Proc Natl Acad Sci USA 2009; 106: 6238-43.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 6238-6243
    • Mars, L.T.1    Araujo, L.2    Kerschen, P.3
  • 64
    • 58149345919 scopus 로고    scopus 로고
    • Big mac attack: Does it play a direct role for monocytes/macrophages in type 1 diabetes?
    • Yang LJ. Big mac attack: does it play a direct role for monocytes/macrophages in type 1 diabetes? Diabetes 2008; 57: 2922-3.
    • (2008) Diabetes , vol.57 , pp. 2922-2923
    • Yang, L.J.1
  • 65
    • 67349255227 scopus 로고    scopus 로고
    • Clinical application of NKT cell biology in type I (autoimmune) diabetes mellitus
    • Fletcher MT, Baxter AG. Clinical application of NKT cell biology in type I (autoimmune) diabetes mellitus. Immunol Cell Biol 2009; 87: 315-23.
    • (2009) Immunol Cell Biol , vol.87 , pp. 315-323
    • Fletcher, M.T.1    Baxter, A.G.2
  • 66
    • 62749198174 scopus 로고    scopus 로고
    • Natural killer T cells and autoimmune disease
    • Wu L, Van Kaer L. Natural killer T cells and autoimmune disease. Curr Mol Med 2009; 9: 4-14.
    • (2009) Curr Mol Med , vol.9 , pp. 4-14
    • Wu, L.1    van Kaer, L.2
  • 67
    • 33847768664 scopus 로고    scopus 로고
    • Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus
    • Kis J, Engelmann P, Farkas K, et al. Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus. J Leukoc Biol 2007; 81: 654-62.
    • (2007) J Leukoc Biol , vol.81 , pp. 654-662
    • Kis, J.1    Engelmann, P.2    Farkas, K.3
  • 68
    • 0032495536 scopus 로고    scopus 로고
    • Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes
    • Wilson SB, Kent SC, Patton KT, et al. Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes. Nature 1998; 391: 177-81.
    • (1998) Nature , vol.391 , pp. 177-181
    • Wilson, S.B.1    Kent, S.C.2    Patton, K.T.3
  • 69
    • 0036782361 scopus 로고    scopus 로고
    • High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes
    • Oikawa Y, Shimada A, Yamada S, et al. High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes. Diabetes Care 2002; 25: 1818-23.
    • (2002) Diabetes Care , vol.25 , pp. 1818-1823
    • Oikawa, Y.1    Shimada, A.2    Yamada, S.3
  • 71
    • 33748745463 scopus 로고    scopus 로고
    • Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes
    • Tsutsumi Y, Jie X, Ihara K, et al. Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes. Diabet Med 2006; 23: 1145-50.
    • (2006) Diabet Med , vol.23 , pp. 1145-1150
    • Tsutsumi, Y.1    Jie, X.2    Ihara, K.3
  • 72
    • 34648847058 scopus 로고    scopus 로고
    • Circulating CD4+CD25 high regulatory T cells and natural killer T cells in children with newly diagnosed type 1 diabetes or with diabetes-associated autoantibodies
    • Oling V, Marttila J, Knip M, Simell O, Ilonen J. Circulating CD4+CD25 high regulatory T cells and natural killer T cells in children with newly diagnosed type 1 diabetes or with diabetes-associated autoantibodies. Ann N Y Acad Sci 2007; 1107: 363-72.
    • (2007) Ann N Y Acad Sci , vol.1107 , pp. 363-372
    • Oling, V.1    Marttila, J.2    Knip, M.3    Simell, O.4    Ilonen, J.5
  • 73
    • 0031423760 scopus 로고    scopus 로고
    • The nonobese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
    • Delovitch TL, Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity 1997; 7: 727-38.
    • (1997) Immunity , vol.7 , pp. 727-738
    • Delovitch, T.L.1    Singh, B.2
  • 74
    • 17644361955 scopus 로고    scopus 로고
    • The NOD mouse: A model of immune dysregulation
    • Anderson MS, Bluestone JA. The NOD mouse: a model of immune dysregulation. Annu Rev Immunol 2005; 23: 447-85.
    • (2005) Annu Rev Immunol , vol.23 , pp. 447-485
    • Anderson, M.S.1    Bluestone, J.A.2
  • 75
    • 0030615214 scopus 로고    scopus 로고
    • Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice
    • Baxter AG, Kinder SJ, Hammond KJ, Scollay R, Godfrey DI. Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice. Diabetes 1997; 46: 572-82.
    • (1997) Diabetes , vol.46 , pp. 572-582
    • Baxter, A.G.1    Kinder, S.J.2    Hammond, K.J.3    Scollay, R.4    Godfrey, D.I.5
  • 76
    • 0031171897 scopus 로고    scopus 로고
    • Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8- thymocytes
    • Godfrey DI, Kinder SJ, Silvera P, Baxter AG. Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8- thymocytes. J Autoimmun 1997; 10: 279-85.
    • (1997) J Autoimmun , vol.10 , pp. 279-285
    • Godfrey, D.I.1    Kinder, S.J.2    Silvera, P.3    Baxter, A.G.4
  • 78
    • 18944365630 scopus 로고    scopus 로고
    • A defect in lineage fate decision during fetal thymic invariant NKT cell development may regulate susceptibility to type 1 diabetes
    • Wagner MJ, Hussain S, Mehan M, Verdi JM, Delovitch TL. A defect in lineage fate decision during fetal thymic invariant NKT cell development may regulate susceptibility to type 1 diabetes. J Immunol 2005; 174: 6764-71.
    • (2005) J Immunol , vol.174 , pp. 6764-6771
    • Wagner, M.J.1    Hussain, S.2    Mehan, M.3    Verdi, J.M.4    Delovitch, T.L.5
  • 79
    • 0035423370 scopus 로고    scopus 로고
    • CD1d-restricted NKT cells: An interstrain comparison
    • Hammond KJ, Pellicci DG, Poulton LD, et al. CD1d-restricted NKT cells: an interstrain comparison. J Immunol 2001; 167: 1164-73.
    • (2001) J Immunol , vol.167 , pp. 1164-1173
    • Hammond, K.J.1    Pellicci, D.G.2    Poulton, L.D.3
  • 80
    • 33745295229 scopus 로고    scopus 로고
    • Genetic and functional analysis of the Nkt1 locus using congenic NOD mice: Improved Valpha14-NKT cell performance but failure to protect against type 1 diabetes
    • Rocha-Campos AC, Melki R, Zhu R, et al. Genetic and functional analysis of the Nkt1 locus using congenic NOD mice: improved Valpha14-NKT cell performance but failure to protect against type 1 diabetes. Diabetes 2006; 55: 1163-70.
    • (2006) Diabetes , vol.55 , pp. 1163-1170
    • Rocha-Campos, A.C.1    Melki, R.2    Zhu, R.3
  • 81
    • 51549118539 scopus 로고    scopus 로고
    • Congenic analysis of the NKT cell control gene Nkt2 implicates the peroxisomal protein Pxmp4
    • Fletcher JM, Jordan MA, Snelgrove SL, et al. Congenic analysis of the NKT cell control gene Nkt2 implicates the peroxisomal protein Pxmp4. J Immunol 2008; 181: 3400-12.
    • (2008) J Immunol , vol.181 , pp. 3400-3412
    • Fletcher, J.M.1    Jordan, M.A.2    Snelgrove, S.L.3
  • 82
    • 0036906618 scopus 로고    scopus 로고
    • NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells
    • Beaudoin L, Laloux V, Novak J, Lucas B, Lehuen A. NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells. Immunity 2002; 17: 725-36.
    • (2002) Immunity , vol.17 , pp. 725-736
    • Beaudoin, L.1    Laloux, V.2    Novak, J.3    Lucas, B.4    Lehuen, A.5
  • 83
    • 31144447382 scopus 로고    scopus 로고
    • NKT cells and IFN-gamma establish the regulatory environment for the control of diabetogenic T cells in the nonobese diabetic mouse
    • Cain JA, Smith JA, Ondr JK, Wang B, Katz JD. NKT cells and IFN-gamma establish the regulatory environment for the control of diabetogenic T cells in the nonobese diabetic mouse. J Immunol 2006; 176: 1645-54.
    • (2006) J Immunol , vol.176 , pp. 1645-1654
    • Cain, J.A.1    Smith, J.A.2    Ondr, J.K.3    Wang, B.4    Katz, J.D.5
  • 84
    • 0032489860 scopus 로고    scopus 로고
    • Alpha/beta-T cell receptor (TCR)+CD4-CD8-(NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10
    • Hammond KJ, Poulton LD, Palmisano LJ, Silveira PA, Godfrey DI, Baxter AG. alpha/beta-T cell receptor (TCR)+CD4-CD8-(NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10. J Exp Med 1998; 187: 1047-56.
    • (1998) J Exp Med , vol.187 , pp. 1047-1056
    • Hammond, K.J.1    Poulton, L.D.2    Palmisano, L.J.3    Silveira, P.A.4    Godfrey, D.I.5    Baxter, A.G.6
  • 85
    • 0032538904 scopus 로고    scopus 로고
    • Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes
    • Lehuen A, Lantz O, Beaudoin L, et al. Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes. J Exp Med 1998; 188: 1831-9.
    • (1998) J Exp Med , vol.188 , pp. 1831-1839
    • Lehuen, A.1    Lantz, O.2    Beaudoin, L.3
  • 86
    • 0035869449 scopus 로고    scopus 로고
    • NK T cell- induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen
    • Laloux V, Beaudoin L, Jeske D, Carnaud C, Lehuen A. NK T cell- induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen. J Immunol 2001; 166: 3749-56.
    • (2001) J Immunol , vol.166 , pp. 3749-3756
    • Laloux, V.1    Beaudoin, L.2    Jeske, D.3    Carnaud, C.4    Lehuen, A.5
  • 87
    • 0034786013 scopus 로고    scopus 로고
    • The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice
    • Hong S, Wilson MT, Serizawa I, et al. The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. Nat Med 2001; 7: 1052-6.
    • (2001) Nat Med , vol.7 , pp. 1052-1056
    • Hong, S.1    Wilson, M.T.2    Serizawa, I.3
  • 88
    • 0035817251 scopus 로고    scopus 로고
    • CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes
    • Wang B, Geng YB, Wang CR. CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes. J Exp Med 2001; 194: 313-20.
    • (2001) J Exp Med , vol.194 , pp. 313-320
    • Wang, B.1    Geng, Y.B.2    Wang, C.R.3
  • 89
    • 0035810999 scopus 로고    scopus 로고
    • Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse
    • Shi FD, Flodstrom M, Balasa B, et al. Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse. Proc Natl Acad Sci USA 2001; 98: 6777-82.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6777-6782
    • Shi, F.D.1    Flodstrom, M.2    Balasa, B.3
  • 90
    • 33644784891 scopus 로고    scopus 로고
    • Transforming growth factor-beta and natural killer T-cells are involved in the protective effect of a bacterial extract on type 1 diabetes
    • Alyanakian MA, Grela F, Aumeunier A, et al. Transforming growth factor-beta and natural killer T-cells are involved in the protective effect of a bacterial extract on type 1 diabetes. Diabetes 2006; 55: 179-85.
    • (2006) Diabetes , vol.55 , pp. 179-185
    • Alyanakian, M.A.1    Grela, F.2    Aumeunier, A.3
  • 91
    • 0029112507 scopus 로고
    • CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice
    • Cardell S, Tangri S, Chan S, Kronenberg M, Benoist C, Mathis D. CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice. J Exp Med 1995; 182: 993-1004.
    • (1995) J Exp Med , vol.182 , pp. 993-1004
    • Cardell, S.1    Tangri, S.2    Chan, S.3    Kronenberg, M.4    Benoist, C.5    Mathis, D.6
  • 92
    • 0035923675 scopus 로고    scopus 로고
    • Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets
    • Naumov YN, Bahjat KS, Gausling R, et al. Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets. Proc Natl Acad Sci USA 2001; 98: 13838-43.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13838-13843
    • Naumov, Y.N.1    Bahjat, K.S.2    Gausling, R.3
  • 93
    • 0034799397 scopus 로고    scopus 로고
    • Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
    • Sharif S, Arreaza GA, Zucker P, et al. Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat Med 2001; 7: 1057-62.
    • (2001) Nat Med , vol.7 , pp. 1057-1062
    • Sharif, S.1    Arreaza, G.A.2    Zucker, P.3
  • 94
    • 33846469009 scopus 로고    scopus 로고
    • Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator
    • Forestier C, Takaki T, Molano A, et al. Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator. J Immunol 2007; 178: 1415-25.
    • (2007) J Immunol , vol.178 , pp. 1415-1425
    • Forestier, C.1    Takaki, T.2    Molano, A.3
  • 95
    • 2342650811 scopus 로고    scopus 로고
    • Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells
    • Mi QS, Ly D, Zucker P, McGarry M, Delovitch TL. Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells. Diabetes 2004; 53: 1303-10.
    • (2004) Diabetes , vol.53 , pp. 1303-1310
    • Mi, Q.S.1    Ly, D.2    Zucker, P.3    McGarry, M.4    Delovitch, T.L.5
  • 96
    • 19944431804 scopus 로고    scopus 로고
    • Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes
    • Chen YG, Choisy-Rossi CM, Holl TM, et al. Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes. J Immunol 2005; 174: 1196-204.
    • (2005) J Immunol , vol.174 , pp. 1196-1204
    • Chen, Y.G.1    Choisy-Rossi, C.M.2    Holl, T.M.3
  • 97
    • 33748500822 scopus 로고    scopus 로고
    • Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells
    • Ly D, Mi QS, Hussain S, Delovitch TL. Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells. J Immunol 2006; 177: 3695-704.
    • (2006) J Immunol , vol.177 , pp. 3695-3704
    • Ly, D.1    Mi, Q.S.2    Hussain, S.3    Delovitch, T.L.4
  • 98
    • 66649113381 scopus 로고    scopus 로고
    • Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice
    • Emamaullee JA, Davis J, Merani S, et al. Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice. Diabetes 2009; 58: 1302-11.
    • (2009) Diabetes , vol.58 , pp. 1302-1311
    • Emamaullee, J.A.1    Davis, J.2    Merani, S.3
  • 99
    • 0343618469 scopus 로고    scopus 로고
    • Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy
    • Illes Z, Kondo T, Newcombe J, Oka N, Tabira T, Yamamura T. Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. J Immunol 2000; 164: 4375-81.
    • (2000) J Immunol , vol.164 , pp. 4375-4381
    • Illes, Z.1    Kondo, T.2    Newcombe, J.3    Oka, N.4    Tabira, T.5    Yamamura, T.6
  • 100
    • 0034742480 scopus 로고    scopus 로고
    • Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage
    • van der Vliet HJ, von Blomberg BM, Nishi N, et al. Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage. Clin Immunol 2001; 100: 144-8.
    • (2001) Clin Immunol , vol.100 , pp. 144-148
    • van der Vliet, H.J.1    von Blomberg, B.M.2    Nishi, N.3
  • 101
    • 0345734356 scopus 로고    scopus 로고
    • A biased Valpha24+ T-cell repertoire leads to circulating NKT-cell defects in a multiple sclerosis patient at the onset of his disease
    • Demoulins T, Gachelin G, Bequet D, Dormont D. A biased Valpha24+ T-cell repertoire leads to circulating NKT-cell defects in a multiple sclerosis patient at the onset of his disease. Immunol Lett 2003; 90: 223-8.
    • (2003) Immunol Lett , vol.90 , pp. 223-228
    • Demoulins, T.1    Gachelin, G.2    Bequet, D.3    Dormont, D.4
  • 102
    • 4644221871 scopus 로고    scopus 로고
    • Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids
    • Parekh VV, Singh AK, Wilson MT, et al. Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids. J Immunol 2004; 173: 3693-706.
    • (2004) J Immunol , vol.173 , pp. 3693-3706
    • Parekh, V.V.1    Singh, A.K.2    Wilson, M.T.3
  • 103
    • 0035905471 scopus 로고    scopus 로고
    • Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis
    • Singh AK, Wilson MT, Hong S, et al. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J Exp Med 2001; 194: 1801-11.
    • (2001) J Exp Med , vol.194 , pp. 1801-1811
    • Singh, A.K.1    Wilson, M.T.2    Hong, S.3
  • 104
    • 0029589931 scopus 로고
    • Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4
    • Yoshimoto T, Bendelac A, Hu-Li J, Paul WE. Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4. Proc Natl Acad Sci USA 1995; 92: 11931-4.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11931-11934
    • Yoshimoto, T.1    Bendelac, A.2    Hu-Li, J.3    Paul, W.E.4
  • 105
    • 53149111593 scopus 로고    scopus 로고
    • Invariant NKT cells regulate experimental autoimmune encephalomyelitis and infiltrate the central nervous system in a CD1d-independent manner
    • Mars LT, Gautron AS, Novak J, et al. Invariant NKT cells regulate experimental autoimmune encephalomyelitis and infiltrate the central nervous system in a CD1d-independent manner. J Immunol 2008; 181: 2321-9.
    • (2008) J Immunol , vol.181 , pp. 2321-2329
    • Mars, L.T.1    Gautron, A.S.2    Novak, J.3
  • 106
    • 0037097505 scopus 로고    scopus 로고
    • Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice
    • Mars LT, Laloux V, Goude K, et al. Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice. J Immunol 2002; 168: 6007-11.
    • (2002) J Immunol , vol.168 , pp. 6007-6011
    • Mars, L.T.1    Laloux, V.2    Goude, K.3
  • 107
    • 0346734191 scopus 로고    scopus 로고
    • CD1-dependent regulation of chronic central nervous system inflammation in experimental autoimmune encephalomyelitis
    • Teige A, Teige I, Lavasani S, et al. CD1-dependent regulation of chronic central nervous system inflammation in experimental autoimmune encephalomyelitis. J Immunol 2004; 172: 186-94.
    • (2004) J Immunol , vol.172 , pp. 186-194
    • Teige, A.1    Teige, I.2    Lavasani, S.3
  • 108
    • 0041968838 scopus 로고    scopus 로고
    • Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: Critical roles for administration route and IFN-gamma
    • Furlan R, Bergami A, Cantarella D, et al. Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma. Eur J Immunol 2003; 33: 1830-8.
    • (2003) Eur J Immunol , vol.33 , pp. 1830-1838
    • Furlan, R.1    Bergami, A.2    Cantarella, D.3
  • 109
    • 17444420728 scopus 로고    scopus 로고
    • The natural killer T cell ligand alpha-galactosylceramide prevents or promotes pristane- induced lupus in mice
    • Singh AK, Yang JQ, Parekh VV, et al. The natural killer T cell ligand alpha-galactosylceramide prevents or promotes pristane- induced lupus in mice. Eur J Immunol 2005; 35: 1143-54.
    • (2005) Eur J Immunol , vol.35 , pp. 1143-1154
    • Singh, A.K.1    Yang, J.Q.2    Parekh, V.V.3
  • 110
    • 0035905485 scopus 로고    scopus 로고
    • Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis
    • Jahng AW, Maricic I, Pedersen B, et al. Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis. J Exp Med 2001; 194: 1789-99.
    • (2001) J Exp Med , vol.194 , pp. 1789-1799
    • Jahng, A.W.1    Maricic, I.2    Pedersen, B.3
  • 111
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto K, Miyake S, Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001; 413: 531-4.
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 113
    • 29744438008 scopus 로고    scopus 로고
    • Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway
    • Miellot A, Zhu R, Diem S, Boissier MC, Herbelin A, Bessis N. Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway. Eur J Immunol 2005; 35: 3704-13.
    • (2005) Eur J Immunol , vol.35 , pp. 3704-3713
    • Miellot, A.1    Zhu, R.2    Diem, S.3    Boissier, M.C.4    Herbelin, A.5    Bessis, N.6
  • 114
    • 0035025559 scopus 로고    scopus 로고
    • Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases
    • Kojo S, Adachi Y, Keino H, Taniguchi M, Sumida T. Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases. Arthritis Rheum 2001; 44: 1127-38.
    • (2001) Arthritis Rheum , vol.44 , pp. 1127-1138
    • Kojo, S.1    Adachi, Y.2    Keino, H.3    Taniguchi, M.4    Sumida, T.5
  • 115
    • 29744467063 scopus 로고    scopus 로고
    • Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis
    • Linsen L, Thewissen M, Baeten K, et al. Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis. Arthritis Res Ther 2005; 7: R493-502.
    • (2005) Arthritis Res Ther , vol.7
    • Linsen, L.1    Thewissen, M.2    Baeten, K.3
  • 117
    • 0033607499 scopus 로고    scopus 로고
    • Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
    • Matsumoto I, Staub A, Benoist C, Mathis D. Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme. Science 1999; 286: 1732-5.
    • (1999) Science , vol.286 , pp. 1732-1735
    • Matsumoto, I.1    Staub, A.2    Benoist, C.3    Mathis, D.4
  • 118
  • 119
    • 20744454301 scopus 로고    scopus 로고
    • The involvement of V(alpha)14 natural killer T cells in the pathogenesis of arthritis in murine models
    • Chiba A, Kaieda S, Oki S, Yamamura T, Miyake S. The involvement of V(alpha)14 natural killer T cells in the pathogenesis of arthritis in murine models. Arthritis Rheum 2005; 52: 1941-8.
    • (2005) Arthritis Rheum , vol.52 , pp. 1941-1948
    • Chiba, A.1    Kaieda, S.2    Oki, S.3    Yamamura, T.4    Miyake, S.5
  • 120
    • 21344439546 scopus 로고    scopus 로고
    • TCR Valpha14 natural killer T cells function as effector T cells in mice with collagen-induced arthritis
    • Ohnishi Y, Tsutsumi A, Goto D, et al. TCR Valpha14 natural killer T cells function as effector T cells in mice with collagen-induced arthritis. Clin Exp Immunol 2005; 141: 47-53.
    • (2005) Clin Exp Immunol , vol.141 , pp. 47-53
    • Ohnishi, Y.1    Tsutsumi, A.2    Goto, D.3
  • 121
    • 12344307565 scopus 로고    scopus 로고
    • NKT cells promote antibody- induced joint inflammation by suppressing transforming growth factor beta1 production
    • Kim HY, Kim HJ, Min HS, et al. NKT cells promote antibody- induced joint inflammation by suppressing transforming growth factor beta1 production. J Exp Med 2005; 201: 41-7.
    • (2005) J Exp Med , vol.201 , pp. 41-47
    • Kim, H.Y.1    Kim, H.J.2    Min, H.S.3
  • 122
    • 34848863949 scopus 로고    scopus 로고
    • A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner
    • Coppieters K, Van Beneden K, Jacques P, et al. A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner. J Immunol 2007; 179: 2300-9.
    • (2007) J Immunol , vol.179 , pp. 2300-2309
    • Coppieters, K.1    van Beneden, K.2    Jacques, P.3
  • 123
    • 0346458555 scopus 로고    scopus 로고
    • Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha- galactosylceramide
    • Chiba A, Oki S, Miyamoto K, Hashimoto H, Yamamura T, Miyake S. Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha- galactosylceramide. Arthritis Rheum 2004; 50: 305-13.
    • (2004) Arthritis Rheum , vol.50 , pp. 305-313
    • Chiba, A.1    Oki, S.2    Miyamoto, K.3    Hashimoto, H.4    Yamamura, T.5    Miyake, S.6
  • 124
    • 34249720998 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of rheumatoid arthritis
    • McInnes IB, Schett G. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 2007; 7: 429-42.
    • (2007) Nat Rev Immunol , vol.7 , pp. 429-442
    • McInnes, I.B.1    Schett, G.2
  • 125
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • Nakae S, Nambu A, Sudo K, Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 2003; 171: 6173-7.
    • (2003) J Immunol , vol.171 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 126
    • 13444256307 scopus 로고    scopus 로고
    • The role of T-cell interleukin-17 in conducting destructive arthritis: Lessons from animal models
    • Lubberts E, Koenders MI, van den Berg WB. The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res Ther 2005; 7: 29-37.
    • (2005) Arthritis Res Ther , vol.7 , pp. 29-37
    • Lubberts, E.1    Koenders, M.I.2    van den Berg, W.B.3
  • 127
    • 0035112485 scopus 로고    scopus 로고
    • Selective reduction and recovery of invariant Valpha24JalphaQ T cell receptor T cells in correlation with disease activity in patients with systemic lupus erythematosus
    • Oishi Y, Sumida T, Sakamoto A, et al. Selective reduction and recovery of invariant Valpha24JalphaQ T cell receptor T cells in correlation with disease activity in patients with systemic lupus erythematosus. J Rheumatol 2001; 28: 275-83.
    • (2001) J Rheumatol , vol.28 , pp. 275-283
    • Oishi, Y.1    Sumida, T.2    Sakamoto, A.3
  • 128
    • 53649099968 scopus 로고    scopus 로고
    • Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity
    • Wither J, Cai YC, Lim S, et al. Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity. Arthritis Res Ther 2008; 10: R108.
    • (2008) Arthritis Res Ther , vol.10
    • Wither, J.1    Cai, Y.C.2    Lim, S.3
  • 129
    • 0141889082 scopus 로고    scopus 로고
    • Repeated alpha-galactosylceramide administration results in expansion of NK T cells and alleviates inflammatory dermatitis in MRL-lpr/lpr mice
    • Yang JQ, Saxena V, Xu H, Van Kaer L, Wang CR, Singh RR. Repeated alpha-galactosylceramide administration results in expansion of NK T cells and alleviates inflammatory dermatitis in MRL-lpr/lpr mice. J Immunol 2003; 171: 4439-46.
    • (2003) J Immunol , vol.171 , pp. 4439-4446
    • Yang, J.Q.1    Saxena, V.2    Xu, H.3    van Kaer, L.4    Wang, C.R.5    Singh, R.R.6
  • 130
    • 23244447028 scopus 로고    scopus 로고
    • Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of systemic lupus erythematosus in (New Zealand Black x New Zealand White)F1 mice
    • Forestier C, Molano A, Im JS, et al. Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of systemic lupus erythematosus in (New Zealand Black x New Zealand White)F1 mice. J Immunol 2005; 175: 763-70.
    • (2005) J Immunol , vol.175 , pp. 763-770
    • Forestier, C.1    Molano, A.2    Im, J.S.3
  • 131
    • 34547932066 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers
    • Yang L, Jhaveri R, Huang J, Qi Y, Diehl A. Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers. Lab Invest 2007 2007; 87: 927-37.
    • (2007) Lab Invest , vol.2007 , Issue.87 , pp. 927-937
    • Yang, L.1    Jhaveri, R.2    Huang, J.3    Qi, Y.4    Diehl, A.5
  • 132
    • 0347988004 scopus 로고    scopus 로고
    • Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus
    • Zeng D, Liu Y, Sidobre S, Kronenberg M, Strober S. Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus. J Clin Invest 2003; 112: 1211-22.
    • (2003) J Clin Invest , vol.112 , pp. 1211-1222
    • Zeng, D.1    Liu, Y.2    Sidobre, S.3    Kronenberg, M.4    Strober, S.5
  • 133
    • 34247216264 scopus 로고    scopus 로고
    • Examining the role of CD1d and natural killer T cells in the development of nephritis in a genetically susceptible lupus model
    • Yang JQ, Wen X, Liu H, et al. Examining the role of CD1d and natural killer T cells in the development of nephritis in a genetically susceptible lupus model. Arthritis Rheum 2007; 56: 1219-33.
    • (2007) Arthritis Rheum , vol.56 , pp. 1219-1233
    • Yang, J.Q.1    Wen, X.2    Liu, H.3
  • 134
    • 0036737837 scopus 로고    scopus 로고
    • Tissue-specific expansion of NKT and CD5+B cells at the onset of autoimmune disease in (NZBxNZW)F1 mice
    • Morshed SR, Mannoor K, Halder RC, et al. Tissue-specific expansion of NKT and CD5+B cells at the onset of autoimmune disease in (NZBxNZW)F1 mice. Eur J Immunol 2002; 32: 2551-61.
    • (2002) Eur J Immunol , vol.32 , pp. 2551-2561
    • Morshed, S.R.1    Mannoor, K.2    Halder, R.C.3
  • 135
    • 44449160501 scopus 로고    scopus 로고
    • Aberrant genetic control of invariant TCR-bearing NKT cell function in New Zealand mouse strains: Possible involvement in systemic lupus erythematosus pathogenesis
    • Tsukamoto K, Ohtsuji M, Shiroiwa W, et al. Aberrant genetic control of invariant TCR-bearing NKT cell function in New Zealand mouse strains: possible involvement in systemic lupus erythematosus pathogenesis. J Immunol 2008; 180: 4530-9.
    • (2008) J Immunol , vol.180 , pp. 4530-4539
    • Tsukamoto, K.1    Ohtsuji, M.2    Shiroiwa, W.3
  • 136
    • 0038189848 scopus 로고    scopus 로고
    • Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice
    • Matsuki N, Stanic AK, Embers ME, Van Kaer L, Morel L, Joyce S. Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice. J Immunol 2003; 170: 5429-37.
    • (2003) J Immunol , vol.170 , pp. 5429-5437
    • Matsuki, N.1    Stanic, A.K.2    Embers, M.E.3    van Kaer, L.4    Morel, L.5    Joyce, S.6
  • 137
    • 0043136663 scopus 로고    scopus 로고
    • Immunoregulatory role of CD1d in the hydrocarbon oil-induced model of lupus nephritis
    • Yang JQ, Singh AK, Wilson MT, et al. Immunoregulatory role of CD1d in the hydrocarbon oil-induced model of lupus nephritis. J Immunol 2003; 171: 2142-53.
    • (2003) J Immunol , vol.171 , pp. 2142-2153
    • Yang, J.Q.1    Singh, A.K.2    Wilson, M.T.3
  • 138
    • 3242734150 scopus 로고    scopus 로고
    • CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice
    • Yang JQ, Chun T, Liu H, et al. CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice. Eur J Immunol 2004; 34: 1723-32.
    • (2004) Eur J Immunol , vol.34 , pp. 1723-1732
    • Yang, J.Q.1    Chun, T.2    Liu, H.3
  • 139
    • 33947732677 scopus 로고    scopus 로고
    • Immunoregulatory role of Jalpha281 T cells in aged mice developing lupus-like nephritis
    • Sireci G, Russo D, Dieli F, et al. Immunoregulatory role of Jalpha281 T cells in aged mice developing lupus-like nephritis. Eur J Immunol 2007; 37: 425-33.
    • (2007) Eur J Immunol , vol.37 , pp. 425-433
    • Sireci, G.1    Russo, D.2    Dieli, F.3
  • 140
    • 0035451795 scopus 로고    scopus 로고
    • Deficiency in beta(2)-microglobulin, but not CD1, accelerates spontaneous lupus skin disease while inhibiting nephritis in MRL-Fas(lpr) nice: An example of disease regulation at the organ level
    • Chan OT, Paliwal V, McNiff JM, Park SH, Bendelac A, Shlomchik MJ. Deficiency in beta(2)-microglobulin, but not CD1, accelerates spontaneous lupus skin disease while inhibiting nephritis in MRL-Fas(lpr) nice: an example of disease regulation at the organ level. J Immunol 2001; 167: 2985-90.
    • (2001) J Immunol , vol.167 , pp. 2985-2990
    • Chan, O.T.1    Paliwal, V.2    McNiff, J.M.3    Park, S.H.4    Bendelac, A.5    Shlomchik, M.J.6
  • 141
    • 38349073476 scopus 로고    scopus 로고
    • Natural killer T cells and innate immune B cells from lupus-prone NZB/W mice interact to generate IgM and IgG autoantibodies
    • Takahashi T, Strober S. Natural killer T cells and innate immune B cells from lupus-prone NZB/W mice interact to generate IgM and IgG autoantibodies. Eur J Immunol 2008; 38: 156-65.
    • (2008) Eur J Immunol , vol.38 , pp. 156-165
    • Takahashi, T.1    Strober, S.2
  • 142
    • 55249119291 scopus 로고    scopus 로고
    • IL-17 and the Th17 lineage in systemic lupus erythematosus
    • Garrett-Sinha LA, John S, Gaffen SL. IL-17 and the Th17 lineage in systemic lupus erythematosus. Curr Opin Rheumatol 2008; 20: 519-25.
    • (2008) Curr Opin Rheumatol , vol.20 , pp. 519-525
    • Garrett-Sinha, L.A.1    John, S.2    Gaffen, S.L.3
  • 143
    • 43049173449 scopus 로고    scopus 로고
    • Invariant natural killer T cells trigger adaptive lymphocytes to churn up bile
    • Joyce S, Van Kaer L. Invariant natural killer T cells trigger adaptive lymphocytes to churn up bile. Cell Host Microbe 2008; 3: 275-7.
    • (2008) Cell Host Microbe , vol.3 , pp. 275-277
    • Joyce, S.1    van Kaer, L.2
  • 144
    • 20144389877 scopus 로고    scopus 로고
    • Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
    • Mattner J, Debord KL, Ismail N, et al. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005; 434: 525-9.
    • (2005) Nature , vol.434 , pp. 525-529
    • Mattner, J.1    Debord, K.L.2    Ismail, N.3
  • 145
    • 33746210257 scopus 로고    scopus 로고
    • Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice
    • Oertelt S, Lian ZX, Cheng CM, et al. Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice. J Immunol 2006; 177: 1655-60.
    • (2006) J Immunol , vol.177 , pp. 1655-1660
    • Oertelt, S.1    Lian, Z.X.2    Cheng, C.M.3
  • 146
    • 39549107358 scopus 로고    scopus 로고
    • Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis
    • Chuang YH, Lian ZX, Yang GX, et al. Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis. Hepatology 2008; 47: 571-80.
    • (2008) Hepatology , vol.47 , pp. 571-580
    • Chuang, Y.H.1    Lian, Z.X.2    Yang, G.X.3
  • 147
    • 33746834534 scopus 로고    scopus 로고
    • Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis
    • Chuang YH, Lian ZX, Tsuneyama K, et al. Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis. J Autoimmun 2006; 26: 232-40.
    • (2006) J Autoimmun , vol.26 , pp. 232-240
    • Chuang, Y.H.1    Lian, Z.X.2    Tsuneyama, K.3
  • 148
    • 0036787437 scopus 로고    scopus 로고
    • Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer
    • Kita H, Naidenko OV, Kronenberg M, et al. Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer. Gastroenterology 2002; 123: 1031-43.
    • (2002) Gastroenterology , vol.123 , pp. 1031-1043
    • Kita, H.1    Naidenko, O.V.2    Kronenberg, M.3
  • 149
    • 67149095289 scopus 로고    scopus 로고
    • Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants
    • Hirschfield GM, Liu X, Xu C, et al. Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants. N Engl J Med 2009; 360(24): 2544-55
    • (2009) N Engl J Med , vol.360 , Issue.24 , pp. 2544-2555
    • Hirschfield, G.M.1    Liu, X.2    Xu, C.3
  • 150
    • 0033594357 scopus 로고    scopus 로고
    • Elevated frequencies of natural killer T lymphocytes in myasthenia gravis
    • Reinhardt C, Melms A. Elevated frequencies of natural killer T lymphocytes in myasthenia gravis. Neurology 1999; 52: 1485-7.
    • (1999) Neurology , vol.52 , pp. 1485-1487
    • Reinhardt, C.1    Melms, A.2
  • 151
    • 24144492393 scopus 로고    scopus 로고
    • Altered populations of natural killer cell and natural killer T cell subclasses in myasthenia gravis
    • Suzuki Y, Onodera H, Tago H, et al. Altered populations of natural killer cell and natural killer T cell subclasses in myasthenia gravis. J Neuroimmunol 2005; 167: 186-9.
    • (2005) J Neuroimmunol , vol.167 , pp. 186-189
    • Suzuki, Y.1
  • 152
    • 0034815536 scopus 로고    scopus 로고
    • NKT-associated markers and perforin in hyperplastic thymuses from patients with Myasthenia gravis
    • Nagane Y, Utsugisawa K, Obara D, Tohgi H. NKT-associated markers and perforin in hyperplastic thymuses from patients with Myasthenia gravis. Muscle Nerve 2001; 24: 1359-64.
    • (2001) Muscle Nerve , vol.24 , pp. 1359-1364
    • Nagane, Y.1    Utsugisawa, K.2    Obara, D.3    Tohgi, H.4
  • 153
    • 0034280106 scopus 로고    scopus 로고
    • Natural killer cells determine the outcome of B cell-mediated autoimmunity
    • Shi FD, Wang HB, Li H, et al. Natural killer cells determine the outcome of B cell-mediated autoimmunity. Nat Immunol 2000; 1: 245-51.
    • (2000) Nat Immunol , vol.1 , pp. 245-251
    • Shi, F.D.1    Wang, H.B.2    Li, H.3
  • 154
    • 29144487073 scopus 로고    scopus 로고
    • Cooperation of invariant NKT cells and CD4+CD25+ T regulatory cells in the prevention of autoimmune myasthenia
    • Liu R, La Cava A, Bai XF, et al. Cooperation of invariant NKT cells and CD4+CD25+ T regulatory cells in the prevention of autoimmune myasthenia. J Immunol 2005; 175: 7898-904.
    • (2005) J Immunol , vol.175 , pp. 7898-7904
    • Liu, R.1    la Cava, A.2    Bai, X.F.3
  • 155
    • 42249084849 scopus 로고    scopus 로고
    • Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category
    • Luger D, Silver PB, Tang J, et al. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med 2008; 205: 799-810.
    • (2008) J Exp Med , vol.205 , pp. 799-810
    • Luger, D.1    Silver, P.B.2    Tang, J.3
  • 156
    • 58149277740 scopus 로고    scopus 로고
    • Activation of invariant NKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses
    • Grajewski RS, Hansen AM, Agarwal RK, et al. Activation of invariant NKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses. J Immunol 2008; 181: 4791-7.
    • (2008) J Immunol , vol.181 , pp. 4791-4797
    • Grajewski, R.S.1    Hansen, A.M.2    Agarwal, R.K.3
  • 158
    • 3242743546 scopus 로고    scopus 로고
    • Schistosoma mansoni and alpha-galactosylceramide: Prophylactic effect of Th1 Immune suppression in a mouse model of Graves' hyperthyroidism
    • Nagayama Y, Watanabe K, Niwa M, McLachlan SM, Rapoport B. Schistosoma mansoni and alpha-galactosylceramide: prophylactic effect of Th1 Immune suppression in a mouse model of Graves' hyperthyroidism. J Immunol 2004; 173: 2167-73.
    • (2004) J Immunol , vol.173 , pp. 2167-2173
    • Nagayama, Y.1    Watanabe, K.2    Niwa, M.3    McLachlan, S.M.4    Rapoport, B.5
  • 159
    • 16844377357 scopus 로고    scopus 로고
    • Mechanisms of heavy metal-induced autoimmunity
    • Rowley B, Monestier M. Mechanisms of heavy metal-induced autoimmunity. Mol Immunol 2005; 42: 833-8.
    • (2005) Mol Immunol , vol.42 , pp. 833-838
    • Rowley, B.1    Monestier, M.2
  • 160
    • 58149184314 scopus 로고    scopus 로고
    • Regulatory roles for NKT cell ligands in environmentally induced autoimmunity
    • Vas J, Mattner J, Richardson S, et al. Regulatory roles for NKT cell ligands in environmentally induced autoimmunity. J Immunol 2008; 181: 6779-88.
    • (2008) J Immunol , vol.181 , pp. 6779-6788
    • Vas, J.1    Mattner, J.2    Richardson, S.3
  • 161
    • 40549091625 scopus 로고    scopus 로고
    • Salivary gland tissue expression of interleukin-23 and interleukin-17 in Sjogren's syndrome: Findings in humans and mice
    • Nguyen CQ, Hu MH, Li Y, Stewart C, Peck AB. Salivary gland tissue expression of interleukin-23 and interleukin-17 in Sjogren's syndrome: findings in humans and mice. Arthritis Rheum 2008; 58: 734-43.
    • (2008) Arthritis Rheum , vol.58 , pp. 734-743
    • Nguyen, C.Q.1    Hu, M.H.2    Li, Y.3    Stewart, C.4    Peck, A.B.5
  • 162
    • 53149131365 scopus 로고    scopus 로고
    • Identification of IL-18 and Th17 cells in salivary glands of patients with Sjogren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18
    • Sakai A, Sugawara Y, Kuroishi T, Sasano T, Sugawara S. Identification of IL-18 and Th17 cells in salivary glands of patients with Sjogren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18. J Immunol 2008; 181: 2898-906.
    • (2008) J Immunol , vol.181 , pp. 2898-2906
    • Sakai, A.1    Sugawara, Y.2    Kuroishi, T.3    Sasano, T.4    Sugawara, S.5
  • 163
    • 42649134787 scopus 로고    scopus 로고
    • Clinical association of serum interleukin-17 levels in systemic sclerosis: Is systemic sclerosis a Th17 disease?
    • Murata M, Fujimoto M, Matsushita T, et al. Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease? J Dermatol Sci 2008; 50: 240-2.
    • (2008) J Dermatol Sci , vol.50 , pp. 240-242
    • Murata, M.1    Fujimoto, M.2    Matsushita, T.3
  • 164
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
    • Lee E, Trepicchio WL, Oestreicher JL, et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 2004; 199: 125-30.
    • (2004) J Exp Med , vol.199 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3
  • 165
    • 61449255982 scopus 로고    scopus 로고
    • A phase I-II study of alpha- galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non- small cell lung cancer
    • Motohashi S, Nagato K, Kunii N, et al. A phase I-II study of alpha- galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non- small cell lung cancer. J Immunol 2009; 182: 2492-501.
    • (2009) J Immunol , vol.182 , pp. 2492-2501
    • Motohashi, S.1    Nagato, K.2    Kunii, N.3
  • 166
    • 33750709275 scopus 로고    scopus 로고
    • A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer
    • Motohashi S, Ishikawa A, Ishikawa E, et al. A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res 2006; 12: 6079-86.
    • (2006) Clin Cancer Res , vol.12 , pp. 6079-6086
    • Motohashi, S.1    Ishikawa, A.2    Ishikawa, E.3
  • 167
    • 20144388064 scopus 로고    scopus 로고
    • A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer
    • Ishikawa A, Motohashi S, Ishikawa E, et al. A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res 2005; 11: 1910-7.
    • (2005) Clin Cancer Res , vol.11 , pp. 1910-1917
    • Ishikawa, A.1    Motohashi, S.2    Ishikawa, E.3
  • 168
    • 0942276861 scopus 로고    scopus 로고
    • Therapeutic activation of Valpha24+Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity
    • Nieda M, Okai M, Tazbirkova A, et al. Therapeutic activation of Valpha24+Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity. Blood 2004; 103: 383-9.
    • (2004) Blood , vol.103 , pp. 383-389
    • Nieda, M.1    Okai, M.2    Tazbirkova, A.3
  • 169
    • 0036896332 scopus 로고    scopus 로고
    • A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors
    • Giaccone G, Punt CJ, Ando Y, et al. A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors. Clin Cancer Res 2002; 8: 3702-9.
    • (2002) Clin Cancer Res , vol.8 , pp. 3702-3709
    • Giaccone, G.1    Punt, C.J.2    Ando, Y.3
  • 170
    • 20844451391 scopus 로고    scopus 로고
    • Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha- galactosyl-ceramide loaded mature dendritic cells in cancer patients
    • Chang DH, Osman K, Connolly J, et al. Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha- galactosyl-ceramide loaded mature dendritic cells in cancer patients. J Exp Med 2005; 201: 1503-17.
    • (2005) J Exp Med , vol.201 , pp. 1503-1517
    • Chang, D.H.1    Osman, K.2    Connolly, J.3
  • 171
    • 37349014075 scopus 로고    scopus 로고
    • Phase I study of alpha- galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer
    • Uchida T, Horiguchi S, Tanaka Y, et al. Phase I study of alpha- galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer. Cancer Immunol Immunother 2008; 57: 337-45.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 337-345
    • Uchida, T.1    Horiguchi, S.2    Tanaka, Y.3
  • 172
    • 34547445595 scopus 로고    scopus 로고
    • Randomized placebo controlled phase I/II trial of alpha-galactosylceramide for the treatment of chronic hepatitis C
    • Veldt BJ, van der Vliet HJ, von Blomberg BM, van Vlierberghe H, Gerken G, Nishi N, et al. Randomized placebo controlled phase I/II trial of alpha-galactosylceramide for the treatment of chronic hepatitis C. J Hepatol 2007; 47: 356-65.
    • (2007) J Hepatol , vol.47 , pp. 356-365
    • Veldt, B.J.1    van der Vliet, H.J.2    von Blomberg, B.M.3    van Vlierberghe, H.4    Gerken, G.5    Nishi, N.6
  • 173
    • 22544445833 scopus 로고    scopus 로고
    • Alpha-galactosylceramide-induced liver injury in mice is mediated by TNF-alpha but independent of Kupffer cells
    • Biburger M, Tiegs G. Alpha-galactosylceramide-induced liver injury in mice is mediated by TNF-alpha but independent of Kupffer cells. J Immunol 2005; 175: 1540-50.
    • (2005) J Immunol , vol.175 , pp. 1540-1550
    • Biburger, M.1    Tiegs, G.2
  • 174
    • 21544456086 scopus 로고    scopus 로고
    • A murine model of NKT cell- mediated liver injury induced by alpha-galactosylceramide/d- galactosamine
    • Fujii H, Seki S, Kobayashi S, et al. A murine model of NKT cell- mediated liver injury induced by alpha-galactosylceramide/d- galactosamine. Virchows Arch 2005; 446: 663-73.
    • (2005) Virchows Arch , vol.446 , pp. 663-673
    • Fujii, H.1    Seki, S.2    Kobayashi, S.3
  • 175
    • 0033939943 scopus 로고    scopus 로고
    • Activation of hepatic NKT cells and subsequent liver injury following administration of alpha- galactosylceramide
    • Osman Y, Kawamura T, Naito T, et al. Activation of hepatic NKT cells and subsequent liver injury following administration of alpha- galactosylceramide. Eur J Immunol 2000; 30: 1919-28.
    • (2000) Eur J Immunol , vol.30 , pp. 1919-1928
    • Osman, Y.1    Kawamura, T.2    Naito, T.3
  • 176
    • 0034681084 scopus 로고    scopus 로고
    • Involvement of decidual Valpha14 NKT cells in abortion
    • Ito K, Karasawa M, Kawano T, et al. Involvement of decidual Valpha14 NKT cells in abortion. Proc Natl Acad Sci USA 2000; 97: 740-4.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 740-744
    • Ito, K.1    Karasawa, M.2    Kawano, T.3
  • 177
    • 33646864753 scopus 로고    scopus 로고
    • The role of invariant natural killer T cells in lupus and atherogenesis
    • Major A, Singh R, Joyce S, Van Kaer L. The role of invariant natural killer T cells in lupus and atherogenesis. Immunol Res 2006; 34: 49-66.
    • (2006) Immunol Res , vol.34 , pp. 49-66
    • Major, A.1    Singh, R.2    Joyce, S.3    van Kaer, L.4
  • 178
    • 4644293314 scopus 로고    scopus 로고
    • Natural killer T cells accelerate atherogenesis in mice
    • Nakai Y, Iwabuchi K, Fujii S, et al. Natural killer T cells accelerate atherogenesis in mice. Blood 2004; 104: 2051-9.
    • (2004) Blood , vol.104 , pp. 2051-2059
    • Nakai, Y.1    Iwabuchi, K.2    Fujii, S.3
  • 179
    • 10644271869 scopus 로고    scopus 로고
    • Quantitative and qualitative differences in proatherogenic NKT cells in apolipoprotein E-deficient mice
    • Major AS, Wilson MT, McCaleb JL, et al. Quantitative and qualitative differences in proatherogenic NKT cells in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2004; 24: 2351-7.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2351-2357
    • Major, A.S.1    Wilson, M.T.2    McCaleb, J.L.3
  • 180
    • 0036676974 scopus 로고    scopus 로고
    • The unconventional lifestyle of NKT cells
    • Kronenberg M, Gapin L. The unconventional lifestyle of NKT cells. Nat Rev Immunol 2002; 2: 557-68.
    • (2002) Nat Rev Immunol , vol.2 , pp. 557-568
    • Kronenberg, M.1    Gapin, L.2
  • 181
    • 0036024567 scopus 로고    scopus 로고
    • NKT cells: Potential targets for autoimmune disease therapy?
    • Hammond KJ, Godfrey DI. NKT cells: potential targets for autoimmune disease therapy? Tissue Antigens 2002; 59: 353-63.
    • (2002) Tissue Antigens , vol.59 , pp. 353-363
    • Hammond, K.J.1    Godfrey, D.I.2
  • 182
    • 0037364854 scopus 로고    scopus 로고
    • Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity
    • Wilson SB, Delovitch TL. Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity. Nat Rev Immunol 2003; 3: 211-22.
    • (2003) Nat Rev Immunol , vol.3 , pp. 211-222
    • Wilson, S.B.1    Delovitch, T.L.2
  • 183
    • 67349171859 scopus 로고    scopus 로고
    • Nanoparticle formulated alpha- galactosylceramide activates NKT cells without inducing anergy
    • Thapa P, Zhang G, Xia C, et al. Nanoparticle formulated alpha- galactosylceramide activates NKT cells without inducing anergy. Vaccine 2009; 27: 3484-8.
    • (2009) Vaccine , vol.27 , pp. 3484-3488
    • Thapa, P.1    Zhang, G.2    Xia, C.3
  • 184
    • 0035159618 scopus 로고    scopus 로고
    • Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of V alpha 14 NK T cells
    • Pal E, Tabira T, Kawano T, Taniguchi M, Miyake S, Yamamura T. Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of V alpha 14 NK T cells. J Immunol 2001; 166: 662-8.
    • (2001) J Immunol , vol.166 , pp. 662-668
    • Pal, E.1    Tabira, T.2    Kawano, T.3    Taniguchi, M.4    Miyake, S.5    Yamamura, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.