Selective requirement for c-Myc at an early stage of Vα14i NKT cell development

Journal of Immunology

Volumn 182, Issue 8, 2009, Pages 4641-4648

  Mycko, Marcin P ^a,c   Ferrero, Isabel ^a   Wilson, Anne ^a   Jiang, Wei ^a   Bianchi, Teresa ^a,d   Trumpp, Andreas ^b,e   MacDonald, H Robson ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b EPFL   (Switzerland)

^c MEDICAL UNIVERSITY OF LODZ   (Poland)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; MESSENGER RNA; MYC PROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; LYMPHOCYTE ANTIGEN RECEPTOR; MYC PROTEIN, MOUSE; PROTEIN BCL 2;

ANIMAL CELL; ARTICLE; CD4 LYMPHOCYTE COUNT; CELL MATURATION; CONTROLLED STUDY; LYMPHOCYTE PROLIFERATION; NATURAL KILLER T CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZINC FINGER MOTIF; ANIMAL; CD8+ T LYMPHOCYTE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HAPLOTYPE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; MOUSE; TIME; TRANSGENIC MOUSE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION REGULATION; HAPLOTYPES; IMMUNOLOGIC MEMORY; INTERLEUKIN-4; MICE; MICE, TRANSGENIC; NATURAL KILLER T-CELLS; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RNA, MESSENGER; TIME FACTORS;

EID: 65249162405     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803394     Document Type: Article

References (44)

1. Bendelac, A., P. B. Savage, and L. Teyton. 2007. The biology of NKT cells. Annu. Rev. Immunol. 25: 297-336.
2. Godfrey, D. I., H. R. MacDonald, M. Kronenberg, M. J. Smyth, and L. Van Kaer. 2004. NKT cells: what's in a name? Nat. Rev. Immunol. 4: 231-237.
3. Benlagha, K., D. G. Wei, J. Veiga, L. Teyton, and A. Bendelac. 2005. Characterization of the early stages of thymic NKT cell development. J. Exp. Med. 202: 485-492. (Pubitemid 41186947)
4. Gadue, P., and P. L. Stein. 2002. NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation. J. Immunol. 169: 2397-2406. (Pubitemid 34920982)
5. + CD1d-dependent precursor stage. J. Exp. Med. 195: 835-844.
6. Godfrey, D. I., and S. P. Berzins. 2007. Control points in NKT-cell development. Nat. Rev. Immunol. 7: 505-518.
7. Kronenberg, M., and I. Engel. 2007. On the road: progress in finding the unique pathway of invariant NKT cell differentiation. Curr. Opin. Immunol. 19: 186-193. (Pubitemid 46356970)
8. MacDonald, H. R., and M. P. Mycko. 2007. Development and selection of Vαl4i NKT cells. Curr. Top. Microbiol. Immunol. 314: 195-212.
9. Matsuda, J. L., and L. Gapin. 2005. Developmental program of mouse Vα14i NKT cells. Curr. Opin. Immunol. 17: 122-130.
10. Griewank, K., C. Borowski, S. Rietdijk, N. Wang, A. Julien, D. G. Wei, A. A. Mamchak, C. Terhorst, and A. Bendelac. 2007. Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 27: 751-762. (Pubitemid 350102258)
11. Borowski, C., and A. Bendelac. 2005. Signaling for NKT cell development: the SAP-FynT connection. J. Exp. Med. 201: 833-836. (Pubitemid 40524451)
12. Egawa, T., G. Eberl, I. Taniuchi, K. Benlagha, F. Geissmann, L. Hennighausen, A. Bendelac, and D. R. Littman. 2005. Genetic evidence supporting selection of the Vα14i NKT cell lineage from double-positive thymocyte precursors. Immunity 22: 705-716. (Pubitemid 40814501)
13. + stage of thymic ontogeny. Proc. Natl. Acad. Sci. USA 102: 5114-5119.
14. Kovalovsky, D., O. U. Uche, S. Eladad, R. M. Hobbs, W. Yi, E. Alonzo, K. Chua, M. Eidson, H. J. Kim, J. S. Im, et al. 2008. The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat. Immunol. 9: 1055-1064.
15. Savage, A. K., M. G. Constantinides, J. Han, D. Picard, E. Martin, B. Li, O. Lantz, and A. Bendelac. 2008. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 29: 391-403.
16. Stanic, A. K., J. S. Bezbradica, J. J. Park, N. Matsuki, A. L. Mora, L. Van Kaer, M. R. Boothby, and S. Joyce. 2004. NF-κB controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes. J. Immunol. 172: 2265-2273.
17. Townsend, M. J., A. S. Weinmann, J. L. Matsuda, R. Salomon, P. J. Farnham, C. A. Biron, L. Gapin, and L. H. Glimcher. 2004. T-bet regulates the terminal maturation and homeostasis of NK and Vα4i NKT cells. Immunity 20: 477-494.
18. Matsuda, J. L., Q. Zhang, R. Ndonye, S. K. Richardson, A. R. Howell, and L. Gapin. 2006. T-bet concomitantly controls migration, survival, and effector functions during the development of Vα14i NKT cells. Blood 107: 2797-2805.
19. Konishi, J., K. Iwabuchi, C. Iwabuchi, M. Ato, J. I. Nagata, K. Onoe, K. I. Nakagawa, M. Kasai, K. Ogasawara, and K. Kawakami. 2000. Thymic epithelial cells responsible for impaired generation of NK-T thymocytes in a lymphoplasia mutant mice. Cell Immunol. 206: 26-35. (Pubitemid 32105808)
20. Elewaut, D., R. B. Shaikh, K. J. Hammond, H. De Winter, A. J. Leishman, S. Sidobre, O. Turovskaya, T. I. Prigozy, L. Ma, T. A. Banks, et al. 2003. NIKdependent RelB activation defines a unique signaling pathway for the development of Vα14i NKT cells. J. Exp. Med. 197: 1623-1633. (Pubitemid 36745338)
21. Sivakumar, V., K. J. Hammond, N. Howells, K. Pfeffer, and F. Weih. 2003. Differential requirement for Rel/nuclear factor κB family members in natural killer T cell development. J. Exp. Med. 197: 1613-1621. (Pubitemid 36745337)
22. Adhikary, S., and M. Eilers. 2005. Transcriptional regulation and transformation by Myc proteins. Nat. Rev. Mol. Cell Biol. 6: 635-645. (Pubitemid 41081267)
23. Douglas, N. C., H. Jacobs, A. L. Bothwell, and A. C. Hayday. 2001. Defining the specific physiological requirements for c-Myc in T cell development. Nat. Immunol. 2: 307-315.
24. Huang, C. Y., A. L. Bredemeyer, L. M. Walker, C. H. Bassing, and B. P. Sleckman. 2008. Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. Eur. J. Immunol. 38: 342-349.
25. Dose, M., I. Khan, Z. Guo, D. Kovalovsky, A. Krueger, H. von Boehmer, K. Khazaie, and F. Gounari. 2006. c-Myc mediates pre-TCR-induced proliferation but not developmental progression. Blood 108: 2669-2677.
26. Bianchi, T., S. Gasser, A. Trumpp, and H. R. MacDonald. 2006. c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. Blood. 107: 3992-3999. (Pubitemid 43726806)
27. Smiley, S. T., M. H. Kaplan, and M. J. Grusby. 1997. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells. Science 275: 977-979. (Pubitemid 27087713)
28. Cui, J., T. Shin, T. Kawano, H. Sato, E. Kondo, I. Toura, Y. Kaneko, H. Koseki, M. Kanno, and M. Taniguchi. 1997. Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors. Science 278: 1623-1626. (Pubitemid 27516281)
29. Brugarolas, J., C. Chandrasekaran, J. I. Gordon, D. Beach, T. Jacks, and G. J. Hannon. 1995. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377: 552-557.
30. Domen, J., S. H. Cheshier, and I. L. Weissman. 2000. The role of apoptosis in the regulation of hematopoietic stem cells: overexpression of BCL-2 increases both their number and repopulation potential. J. Exp. Med. 191: 253-264. (Pubitemid 30060915)
31. Trumpp, A., Y. Refaeli, T. Oskarsson, S. Gasser, M. Murphy, G. R. Martin, and J. M. Bishop. 2001. c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature 414: 768-773. (Pubitemid 34000776)
32. Wolfer, A., T. Bakker, A. Wilson, M. Nicolas, V. Ioannidis, D. R. Littman, P. P. Lee, C. B. Wilson, W. Held, H. R. MacDonald, and F. Radtke. 2001. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat. Immunol. 2: 235-241. (Pubitemid 33706000)
33. Wilson, A., M. J. Murphy, T. Oskarsson, K. Kaloulis, M. D. Bettess, G. M. Oser, A. C. Pasche, C. Knabenhans, H. R. Macdonald, and A. Trumpp. 2004. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev. 18: 2747-2763. (Pubitemid 39507768)
34. + cells in the liver of mice. J. Exp. Med. 180: 699-704.
35. Schumann, J., R. B. Voyle, B. Y. Wei, and H. R. MacDonald. 2003. Cutting edge: influence of the TCR Vβ domain on the avidity of CD1d:α- galactosylceramide binding by invariant Vα14 NKT cells. J. Immunol. 170: 5815-5819. (Pubitemid 36682558)
36. Laurenti, E., B. Varnum-Finney, A. Wilson, I. Ferrero, W. E. Blanco-Bose, A. Ehninger, P. S. Knoepfler, P. F. Cheng, H. R. MacDonald, R. N. Eisenman, et al. 2008. Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. Cell Stem Cell 3: 611-624.
37. + T lymphocytes. J. Immunol. 170: 1150-1157.
38. Stetson, D. B., M. Mohrs, R. L. Reinhardt, J. L. Baron, Z. E. Wang, L. Gapin, M. Kronenberg, and R. M. Locksley. 2003. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J. Exp. Med. 198: 1069-1076.
39. Minagawa, M., H. Watanabe, C. Miyaji, K. Tomiyama, H. Shimura, A. Ito, M. Ito, J. Domen, I. L. Weissman, and K. Kawai. 2002. Enforced expression of BCL-2 restores the number of NK cells, but does not rescue the impaired development of NKT cells or intraepithelial lymphocytes, in IL-2/IL-15 receptor β-chain-deficient mice. J. Immunol. 169: 4153-4160. (Pubitemid 35178185)
40. Oskarsson, T., M. A. Essers, N. Dubois, S. Offner, C. Dubey, C. Roger, D. Metzger, P. Chambon, E. Hummler, P. Beard, and A. Trumpp. 2006. Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene. Genes Dev. 20: 2024-2029. (Pubitemid 44157454)
41. de Alboran, I. M., R. C. O'Hagan, F. Gartner, B. Malynn, L. Davidson, R. Rickert, K. Rajewsky, R. A. DePinho, and F. W. Alt. 2001. Analysis of c-Myc function in normal cells via conditional gene-targeted mutation. Immunity 14: 45-55.
42. + T-cell development. Nat. Rev. Immunol. 7: 479-485.
43. Veillette, A., Z. Dong, and S. Latour. 2007. Consequence of the SLAM-SAP signaling pathway in innate-like and conventional lymphocytes. Immunity 27: 698-710. (Pubitemid 350102266)
44. Horai, R., K. L. Mueller, R. A. Handon, J. L. Cannons, S. M. Anderson, M. R. Kirby, and P. L. Schwartzberg. 2007. Requirements for selection of conventional and innate T lymphocyte lineages. Immunity 27: 775-785. (Pubitemid 350102265)