Genetic and functional analysis of the Nkt1 locus using congenic NOD mice: Improved Vα14-NKT cell performance but failure to protect against type 1 diabetes

Diabetes

Volumn 55, Issue 4, 2006, Pages 1163-1170

  Rocha Campos, Ana Claudia ^a   Melki, Rahma ^b   Zhu, Ren ^a   Deruytter, Nathalie ^b   Damotte, Diane ^b,c   Dy, Michel ^a   Herbelin, André ^a,d   Garchon, Henri Jean ^b,d  

^a CNRS   (France)

^b INSERM   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

GalCer, galatosylceramide; APC, allophycocyanin; ELISA, enzyme linked immunosorbent assay; FITC, fluorescein isothiocyanate; IFN , interferon; IL, interleukin; iNKT cell, invariant natural killer T cell

Indexed keywords

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; ALPHA GALACTOSYLCERAMIDE; CD150 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CELL DESTRUCTION; CELL FUNCTION; CHROMOSOME 1; CHROMOSOME MAP; CONGENIC STRAIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE PREDISPOSITION; GENE; GENE CLUSTER; GENE LOCUS; GENETIC ANALYSIS; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INTROGRESSION; MOUSE; NATURAL KILLER T CELL; NKT1 GENE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; ANIMAL; C57BL MOUSE; CROSS BREEDING; DENDRITIC CELL; FLOW CYTOMETRY; GENETIC VARIABILITY; GENETICS; IMMUNOLOGY; LIVER; NATURAL KILLER CELL; NONOBESE DIABETIC MOUSE; SPLEEN;

ANIMALS; CHROMOSOME MAPPING; CROSSES, GENETIC; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; FLOW CYTOMETRY; KILLER CELLS, NATURAL; LIVER; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; SPLEEN; VARIATION (GENETICS);

EID: 33745295229     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/diabetes.55.04.06.db05-0908     Document Type: Article

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