Genetic dissection of Vα14Jα18 natural T cell number and function in autoimmune-prone mice

Journal of Immunology

Volumn 170, Issue 11, 2003, Pages 5429-5437

  Matsuki, Naoto ^a   Stanic, Aleksandar K ^a   Embers, Monica E ^b   Van Kaer, Luc ^a   Morel, Laurence ^c   Joyce, Sebastian ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CELL COUNT; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE RELEASE; GENE CONTROL; GENE LOCUS; GENE MAPPING; GENETIC RESISTANCE; GENETIC SUSCEPTIBILITY; IMMUNOREGULATION; IMMUNOSTIMULATION; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; T LYMPHOCYTE;

EID: 0038189848     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.11.5429     Document Type: Article

References (57)

1. Leiter, E., and M. Atkinson. 1998. NOD Mice and Related Strains: Research Applications in Diabetes, AIDS, Cancer and Other Diseases. R. G. Landes Company, Austin.
2. Hattori, M., J. B. Buse, R. A. Jackson, L. Glimcher, M. E. Dorf. M. Minami, S. Makino, K. Moriwaki, H. Kuzuya, H. Imura, et al. 1986. The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex. Science 231:733.
3. Ikegami, H., G. S. Eisenbarth, and M. Hattori. 1990. Major histocompatibility complex-linked diabetogenic gene of the nonobese diabetic mouse: analysis of genomic DNA amplified by the polymerase chain reaction. J. Clin. Invest. 85:18.
4. Prochazka, M., E. H. Leiter. D. V. Serreze. and D. L. Coleman. 1987. Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice. Science 237:286.
5. Wicker, L. S., B. J. Miller, L. Z. Coker, S. E. McNally, S. Scott. Y. Mullen, and M. C. Appel. 1987, Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse. J. Exp. Med. 165:1639.
6. Wicker, L. S., J. A. Todd, and L. B. Peterson. 1995. Genetic control of autoimmune diabetes in the NOD mouse. Annu. Rev. Immunol. 13:179.
7. Hong, S., M. T. Wilson, I. Serizawa, L. Wu. N. Singh. O. V. Naidenko, T. Miura, T. Haba, D. C. Scherer, J. Wei, et al. 2001. The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. Nat. Med. 7:1052.
8. Sharif. S., G. A. Arreaza, P. Zucker, Q. S. Mi, J. Sondhi, O. V. Naidenko, M. Kronenberg, Y. Koezuka, T. L. Delovitch. J. M. Gombert, et al. 2001. Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune type I diabetes. Nat. Med. 7:1057.
9. Wang, B., Y. B. Geng, and C. R. Wang. 2001. CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes. J. Exp. Med. 194:313.
10. Naumov, Y. N., K. S. Bahjat, R. Gausling, R. Abraham. M. A. Exley, Y. Koezuka, S. B, Balk, J. L. Strominger, M. Clare-Salzer, and S. B. Wilson, 2001. Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets. Proc. Natl. Acad. Sci. USA 98:13838.
11. + T cells in autoimmune diabetes. Nat. Immunol. 2:1117.
12. + subset. J. Immunol. 145:1039.
13. + thymocytes selected by MHC class I molecules. Science 263:1774.
14. - T cells. J. Exp. Med. 186:109.
15. + T cells, J. Exp. Med. 187:2109.
16. + cells. J. Immunol. 145:3209.
17. - single positive thymocyte subpopulation that expresses a highly skewed T cell antigen receptor family. Proc. Natl. Acad. Sci. USA 89:6506.
18. - T cells in mice and humans. J. Exp. Med. 180:1097.
19. Kawano. T., J. Cui. Y. Koezuka. I. Toura, Y. Kaneko, K. Motoki. H. Ueno, R. Nakagawa, H. Sato, E. Kondo. et al. 1997. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides. Science 278:1626.
20. Benlagha, K., A. Weiss, A. Beavis, L. Teyton, and A. Bendelac. 2000. In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J. Exp. Med. 191:1895.
21. Matsuda, J. L., O. V. Naidenko, L. Gapin, T. Nakayama, M. Taniguchi. C.-R. Wang, Y. Koezuka, and M. Kronenberg. 2000. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 192:741.
22. MacDonald. H. R. 2000. CD1d-glycolipid tetramers: a new tool to monitor natural killer T cells in health and disease, J. Exp. Med. 192:F15.
23. Joyce, S. 2001. CD1d and natural T cells: how their properties jump start the immune system. Cell. Mol. Life Sci. 58:442.
24. - T-cell deficiency and IDDM in NOD/Lt mice. Diabetes 46:572.
25. +-like thymocytes in the NOD mice. Eur. J. Immunol. 26:2989.
26. Hammond, K. J., D. G. Pellicci, L. D. Poulton, O. V. Naidenko, A. A. Scalzo, A. G. Baxter, and D. I. Godfrey. 2001. CD1d-restricted NKT cells: an interstrain comparison. J. Immunol. 167:1164.
27. + NK T cells associated with disease development in autoimmune prone mice. J. Immunol. 156:4035.
28. Takeda, K., and G. Dennert. 1993. The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of the natural killer type 1 positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion and autoimmune symptoms. J. Exp. Med. 177:155.
29. - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in non-obese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10. J. Exp. Med. 187:1047.
30. Lehuen, A., O. Lantz, L. Beaudoin, V. Laloux, C. Carnaud, A. Bendelac, J. F. Bach, and R. C. Monteiro. 1998. Overexpression of natural killer T cells protects Vα14Ja281 transgenic nonobese diabetic mice against diabetes. J. Exp. Med. 188:1831.
31. Shi, F. D., M. Flodstrom, B. Balasa, S. H. Kim, K. Van Gunst, J. L. Strominger, S. B. Wilson, and N. Sarvetnick. 2001. Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse. Proc. Natl. Acad. Sci. USA 98:6777.
32. Singh, N., S. Hong, D. C. Scherer, I. Serizawa, N. Burdin, M. Kronenberg, Y. Koezuka, and L. Van Kaer. 1999. Activation of NK T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. J. Immunol. 163:2373.
33. Laloux, V., L. Beaudoin, C. Ronet, and A. Lehuen. 2002. Phenotypic and functional differences between NKT cells colonizing splanchnic and peripheral lymph nodes. J. Immunol. 168:3251.
34. Wilson, S. B., S. C. Kent, K. T. Patton, T. Orban, R. A. Jackson, M. Exley, S. Porcelli, D. A. Schatz, M. A. Atkinson, S. P. Balk, et al. 1998. Extreme Th1 bias of invariant Vα24JaQ T cells in type 1 diabetes. Nature 391:177.
35. - T cells. J. Exp. Med. 180:1171.
36. Gumperz, J. E., S. Miyake, T. Yamamura, and M. B. Brenner. 2002. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 195:625.
37. Lee, P. T., K. Benlagha, L. Teyton. and A. Bendelac. 2002. Distinct functional lineages of human Vα24 natural killer T cells. J. Exp. Med. 195:637.
38. - and heterogeneous with respect to TCRβ expression. Hum. Immunol. 48:63.
39. Lee, P. T., A. Putnam, K. Benlagha, L. Teyton, P. A. Gottlieb, and A. Bendelac. 2002. Testing the NKT cell hypothesis of human IDDM pathogenesis. J. Clin. Invest. 110:793.
40. Motsinger, A., D. W. Haas. A. K. Stanic, L. Van Kaer, S. Joyce, and D. Unutmaz. 2002. CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection. J. Exp. Med. 195:869.
41. Mendiratta, S. K., W. D. Martin, S. Hong, A. Boesteanu, S. Joyce, and L. Van Kaer. 1997. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6:469.
42. Wada, H., Y. Noguchi, M. W. Marino, A. R. Dunn, and L. J. Old. 1997. T cell functions in granulocyte/macrophage colony-stimulating factor deficient mice. Proc. Natl. Acad. Sci. USA 94:12557.
43. Stanic, A. K., A. D. De Silva, V. Sriram, S. Ichikawa, Y. Hirabayashi, L. Van Kaer, K. Hayakawa, R. R. Brutkiewicz. and S. Joyce. 2003. Defective presentation of the CD1d1-restricted natural Vα14Jα18 NKT lymphocyte antigen caused by β-D-glucosylceramide synthase deficiency. Proc. Natl. Acad. Sci. USA 100:1849.
44. Boesteanu, A., A. D. De Silva, H. Nakajima, W. J. Leonard, J. J. Peschon, and S. Joyce. 1997. Distinct roles for signals relayed through the common cytokine receptor γ chain and interleukin 7 receptor α chain in natural T cell development. J. Exp. Med. 186:331.
45. Prochazka, M., D. V. Serreze, W. N. Frankel, and E. H. Leiter. 1992. NOR/Lt: MHC-matched diabetes-resistant control strain for NOD mice. Diabetes 41:98.
46. Serreze, D. V., M. Prochazka, P. C. Reifsnyder, M. M. Bridgett, and E. H. Leiter. 1994. Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene. J. Exp. Med. 180:1553.
47. Camaud, C., D. Lee, O. Donnars, S.-H. Park, A. Beavis, Y. Koezuka, and A. Bendelac. 1999. Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells. J. Immunol. 163:4647.
48. Smiley, S. T., M. H. Kaplan, and M. J. Grusby. 1997. Immunoglobulin E production in the absence of interleukin-4 secreting CD1 dependent cells. Science 275:977.
49. Lyons, P. A., W. W. Hancock, P. Denny, C. J. Lord, N. J. Hill, N. Armitage, T. Siegmund, J. A. Todd, M. S. Phillips, J. F. Hess, et al. 2000. The NOD 1dd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, TNFr2, and Cd137. Immunity 13:107.
50. Camaud, C., J. Gombert, O. Donnars, H. Garchon, and A. Herbelin. 2001. Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex. J. Immunol. 166:2404.
51. Eberl, G., B. Lowin-Kropf, and H. R. MacDonald. 1999. NKT cell development is selectively impaired in Fyn-deficient mice. J. Immunol. 163:4091.
52. Gadue. P., N. Morton, and P. L. Stein. 1999. The src family tyrosine kinase Fyn regulates natural killer T cell development. J. Exp. Med. 190:1189.
53. Kronenberg, M., and L. Gapin. 2002. The unconventional lifestyle of NKT cells. Nat. Rev. Immunol. 2:557.
54. + T cells from IL-7-deficient mice have normal distribution and selection but exhibit impaired cytokine production. Int. Immunol. 8:1759.
55. + T) cells, natural killer cells, and intestinal intraepithelial T cells. J. Exp. Med. 187:967.
56. + T cell development and early IL-4 production in CD1 deficient mice. Immunity 6:459.
57. Sato. H., T. Nakayama, Y. Tanaka, M. Yamashita, Y. Shibata, E. Kondo, Y. Saito, and M. Taniguchi. 1999. Induction of differentiation of pre-NKT cells to mature Vα14 NKT cells by granulocyte/macrophage colony-stimulating factor. Proc. Natl. Acad. Sci. USA 96:7439.