Elevated frequencies of natural killer T lymphocytes in myasthenia gravis

Neurology

Volumn 52, Issue 7, 1999, Pages 1485-1487

  Reinhardt, Carsten ^a,b   Melms, Arthur ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 4;

ADULT; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; ELECTROPHYSIOLOGY; FEMALE; GENE FREQUENCY; HELPER CELL; HUMAN; IMMUNOGENICITY; KILLER CELL; LYMPHOCYTE SUBPOPULATION; MALE; MYASTHENIA GRAVIS; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; T LYMPHOCYTE ACTIVATION;

EID: 0033594357     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.52.7.1485     Document Type: Article

References (10)

1. Drachman DB. Myasthenia gravis. N Engl J Med 1994;330: 1797-1810.
2. Hawke S, Matsuo H, Nicolle M, Malcharek G, Melms A, Willcox N. Autoimmune T cells in myasthenia gravis: heterogeneity and potential for specific immunotargeting. Immunol Today 1997;17:307-311.
3. Bendelac A, Rivera MN, Park S-H, Roark JH. Mouse GD1-specific NK1 T cells: development, specificity and function. Annu Rev Immunol 1997;15:535-562.
4. Prussin C, Foster B. TCR Vα24 and Vβ11 coexpression defines a human NK1 T cell analog containing a unique Th0 subpopulation. J Immunol 1997;159:5862-5870.
5. Vincent A, Newsom-Davis J. Acetylcholine receptor antibody characteristics in myasthenia gravis. I. Patients with generalized myasthenia or disease restricted to ocular muscles. Clin Exp Immunol 1982;49:257-265.
6. Reinhardt C, Melms A. Skewed TCRVβ repertoire in human thymus persists after thymic emigration: influence of genomic imposition, thymic maturation and environmental challenge on human TCRVβ usage in vivo. Immunobiology 1998;199: 74-86.
7. Wang ZY, Link H, Ljungdahl A, et al. Induction of IFN-γ, IL-4 and TGF-β in rats orally tolerized against EAMG. Cell Immunol 1994;157:353-368.
8. Asthana D, Fujii Y, Huston G, Lindstrom J. Regulation of antibody production by helper T cell clones in EAMG is mediated by IL-4 and antigen-specific T cell factors. Clin Immunol Immunopathol 1993;67:240-248.
9. Wilson SB, Kent SC, Patton KT, et al. Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes. Nature 1998; 391:177-181.
10. + thymocytes. J Immunol 1991;146:1113-1117.