Selective reduction and recovery of invariant Vα24JαQ T cell receptor T cells in correlation with disease activity in patients with systemic lupus erythematosus

Journal of Rheumatology

Volumn 28, Issue 2, 2001, Pages 275-283

  Oishi, Y ^a   Sumida, T ^a   Sakamoto, A ^a   Kita, Y ^a   Kurasawa, K ^a   Nawata, Y ^a   Takabayashi, K ^a   Takahashi, H ^a   Yoshida, S ^a   Taniguchi, M ^a   Saito, Y ^a   Iwamoto, I ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

CD4 CD8 double negative T cells; Corticosteroids; Invariant V 24J Q TCR T cells; Systemic lupus erythematosus

Indexed keywords

CD1 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; PREDNISOLONE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE ACTIVITY; FEMALE; HUMAN; IMMUNOMODULATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

ADULT; CD4-CD8 RATIO; CELL COUNT; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 0035112485     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Mouse NK1+ T cells
2. NKI.I+ T cell receptor-α/β cells: New clues to their origin, specificity, and function
3. Mouse NK1.1+ T cells: A new family of T cells
4. Mouse CD1-specific NK1 T cells: Development, specificity, and function
5. An invariant T cell receptor a chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans
6. Predominant expression of invariant Vα14+ TCRα chain in NK1.1+ T cell populations
7. CD1 recognition by mouse NK1+ T lymphocytes
8. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells
9. Impaired NKI+ T cell development and early IL-4 production in CD1-deficient mice
10. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4
11. NK1.1+ CD4+ CD8- thymocytes with specific lymphokine secretion
12. CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3
13. Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production
14. The development of autoimmunity in C57BL/6 1pr mice correlates with the disappearance of natural killer type 1-positive cells: Evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms
15. Selective reduction of Vα14+ NK T cells associated with disease development in autoimmune-prone mice
16. Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse
17. Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCRα chain
18. T cell receptor α/β CD4-8-subset
19. An invariant Vα24-JαQ/Vβ11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells
20. Requirements for CD1d recognition by human invariant Vα24+ CD4-CD8- T cells
21. Human T cells expressing an invariant Vα24-JαQ TCRa are CD4- and heterogeneous with respect to TCRβ expression
22. Close phenotypic and functional similarities between human and murine αβ T cells expressing invariant TCRα-chains
23. TCR Vα24 and Vβ11 coexpression defines a human NK1 T cell analog containing a unique Th0 subpopulation
24. The 1982 revised criteria for the classification of systemic lupus erythematosus
25. The Committee on Prognosis Studies in SLE. Derivation of the SLEDAI. A disease activity index for lupus patients
26. T cell receptor α/β expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis
27. Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis
28. Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes
29. Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4
30. Myelin proteolipid protein-induced experimental allergic encephalomyelitis. Variations of disease expression in different strains of mice
31. The murine autoimmune diabetes model: NOD and related strains
32. Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus
33. Cytokine profile in systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases
34. Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis
35. Plasma concentration of IL-6 in systemic lupus erythematosus; an indicator of disease activity?
36. In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjögren's syndrome, and systemic lupus erythematosus. A potential mechanism of B lymphocyte hyperactivity and autoimmunity
37. Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10:interferon-γ-secreting cells in the peripheral blood
38. Cytokine abnormalities in human lupus
39. Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus
40. Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus
41. Natural killer cells and interferon responses in patients with systemic lupus erythematosus
42. IFN-g modulates CD1d surface expression on intestinal epithelia
43. 1L-4-producing NK1.1+ T cells are resistant to glucocorticoid-induced apoptosis: Implications for the Th1/Th2 balance
44. Differential responses of invariant Vα24JαQ T cells and MHC class II-restricted CD4+ T cells to dexamethasone
45. Requirement for Vα14 NKT cells in IL-12 mediated rejection of tumors
46. Lymphocyte responses and cytokines
47. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
48. T helper cell subsets in insulin-dependent diabetes
49. Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice
50. Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice
51. CD4-CD8- T cells bearing invariant Vα24JαQ TCR-α chain are decreased in patients with atopic diseases
52. Cytotoxicity of fresh NK 1.1+ T cell receptor α/β+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target