Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 14, 2007, Pages 5977-5982

  Porubsky, Stefan ^a   Speak, Anneliese O ^b   Luckow, Bruno ^c   Cerundolo, Vincenzo ^d   Platt, Frances M ^b   Gröne, Hermann Josef ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF MUNICH   (Germany)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

A3galt2; CD1d; Dendritic cell; Glycosphingolipid; KRN7000

Indexed keywords

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; ALPHA 1,3 GALACTOSYLTRANSFERASE; CD1D ANTIGEN; CD69 ANTIGEN; CERAMIDE TRIHEXOSIDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 4; INTERLEUKIN 6; ISOGLOBOTRIHEXOSYLCERAMIDE; LIPID; MONOCYTE CHEMOTACTIC PROTEIN 1; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CD86 ANTIGEN; GALACTOSYLTRANSFERASE; GLOBOSIDE; INTERLEUKIN 12; ISOGLOBOTRIAOSYLCERAMIDE; LEUKOCYTE ANTIGEN; T LYMPHOCYTE ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL SELECTION; CONTROLLED STUDY; DENDRITIC CELL; ENZYME DEFICIENCY; GENETIC CODE; IMMUNOREGULATION; LIVER; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; THYMOCYTE; THYMUS; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; BLOOD; COMPARATIVE STUDY; GENETICS; HETEROZYGOTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE MUTANT;

MUS;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD86; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CHEMOKINE CCL2; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GALACTOSYLTRANSFERASES; GLOBOSIDES; HETEROZYGOTE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-4; INTERLEUKIN-6; KILLER CELLS, NATURAL; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 34247592222     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0611139104     Document Type: Article

References (37)

1. Kasahara M, Nakaya J, Satta Y, Takahata N (1997) Trends Genet 13:90-92.
2. Brigl M, Brenner MB (2004) Annu Rev Immunol 22:817-890.
3. Porcelli SA, Modlin RL (1999) Annu Rev Immunol 17:297-329.
4. Kronenberg M, Gapin L (2002) Nat Rev Immunol 2:557-568.
5. Makino Y, Kanno R, Ito T, Higashino K, Taniguchi M (1995) Int Immunol 7:1157-1161.
6. Arase H, Arase N, Ogasawara K, Good RA, Onoe K (1992) Proc Natl Acad Sci USA 89:6506-6510.
7. Lantz O, Bendelac A (1994) J Exp Med 180:1097-1106.
8. Kawano T, Cui J, Koezuka Y, Toura I, Kaneko Y, Motoki K, Ueno H, Nakagawa R, Sato H, Kondo E, et al. (1997) Science 278:1626-1629.
9. Hansen DS, Schofield L (2004) Int J Parasitol 34:15-25.
10. Taniguchi M, Harada M, Kojo S, Nakayama T, Wakao H (2003) Annu Rev Immunol 21:483-513.
11. Wei DG, Curran SA, Savage PB, Teyton L, Bendelac A (2006) J Exp Med 203:1197-1207.
12. Roberts TJ, Sriram V, Spence PM, Gui M, Hayakawa K, Bacik I, Bennink JR, Yewdell JW, Brutkiewicz RR (2002) J Immunol 168:5409-5414.
13. Chiu YH, Park SH, Benlagha K, Forestier C, Jayawardena-Wolf J, Savage PB, Teyton L, Bendelac A (2002) Nat Immunol 3:55-60.
14. Smiley ST, Kaplan MH, Grusby MJ (1997) Science 275:977-979.
15. Zhou D, Cantu C, III, Sagiv Y, Schrantz N, Kulkarni AB, Qi X, Mahuran DJ, Morales CR, Grabowski GA, Benlagha K, et al. (2004) Science 303:523-527.
16. Honey K, Benlagha K, Beers C, Forbush K, Teyton L, Kleijmeer MJ, Rudensky AY, Bendelac A (2002) Nat Immunol 3:1069-1074.
17. Stanic AK, De Silva AD, Park JJ, Sriram V, Ichikawa S, Hirabyashi Y, Hayakawa K, Van Kaer L, Brutkiewicz RR, Joyce S (2003) Proc Natl Acad Sci USA 100:1849-1854.
18. Zhou D, Mattner J, Cantu C, III, Schrantz N, Yin N, Gao Y, Sagiv Y, Hudspeth K, Wu YP, Yamashita T, et al. (2004) Science 306:1786-1789.
19. Xia C, Yao Q, Schumann J, Rossy E, Chen W, Zhu L, Zhang W, De Libero G, Wang PG (2006) Bioorg Med Chem Lett 16:2195-2199.
20. Mattner J, Debord KL, Ismail N, Goff RD, Cantu C, III, Zhou D, Saint-Mezard P, Wang V, Gao Y, Yin N, et al. (2005) Nature 434:525-529.
21. Gadola SD, Silk JD, Jeans A, Illarionov PA, Salio M, Besra GS, Dwek R, Butters TD, Platt FM, Cerundolo V (2006) J Exp Med 203:2293-2303.
22. Sagiv Y, Hudspeth K, Mattner J, Schrantz N, Stern RK, Zhou D, Savage PB, Teyton L, Bendelac A (2006) J Immunol 177:26-30.
23. Godfrey DI, McConville MJ, Pellicci DG (2006) J Exp Med 203:2229-2232.
24. Speak AO, Salio M, Neville DCA, Fontaine J, Priestman DA, Platt N, Heare T, Butters TD, Dwek RA, Trottein F, et al. (2007) Proc Natl Acad Sci USA 104:5971-5976.
25. Keusch JJ, Manzella SM, Nyame KA, Cummings RD, Baenziger JU (2000) J Biol Chem 275:25308-25314.
26. Wiggins CA, Munro S (1998) Proc Natl Acad Sci USA 95:7945-7950.
27. Schwenk F, Baron U, Rajewsky K (1995) Nucleic Acids Res 23:5080-5081.
28. Benlagha K, Kyin T, Beavis A, Teyton L, Bendelac A (2002) Science 296:553-555.
29. Kitamura H, Iwakabe K, Yahata T, Nishimura S, Ohta A, Ohmi Y, Sato M, Takeda K, Okumura K, Van Kaer L, et al. (1999) J Exp Med 189:1121-1128.
30. Matsuda JL, Naidenko OV, Gapin L, Nakayama T, Taniguchi M, Wang CR, Koezuka Y, Kronenberg M (2000) J Exp Med 192:741-754.
31. Tomura M, Yu WG, Ahn HJ, Yamashita M, Yang YF, Ono S, Hamaoka T, Kawano T, Taniguchi M, Koezuka Y, et al. (1999) J Immunol 163:93-101.
32. Vincent MS, Leslie DS, Gumperz JE, Xiong X, Grant EP, Brenner MB (2002) Nat Immunol 3:1163-1168.
33. Milland J, Christiansen D, Lazarus BD, Taylor SG, Xing PX, Sandrin MS (2006) J Immunol 176:2448-2454.
34. Taylor SG, McKenzie IF, Sandrin MS (2003) Glycobiology 13:327-337.
35. Muyrers JP, Zhang Y, Stewart AF (2001) Trends Biochem Sci 26:325-331.
36. Chomczynski P, Sacchi N (1987) Anal Biochem 162:156-159.
37. Korten S, Anderson RJ, Hannan CM, Sheu EG, Sinden R, Gadola S, Taniguchi M, Hill AV (2005) Infect Immun 73:849-858.