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Volumn 107, Issue , 2010, Pages 39-56

Obesity, Cholesterol, and Clear-Cell Renal Cell Carcinoma (RCC)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CARRIER PROTEIN; CELL SURFACE RECEPTOR; CHOLESTEROL; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; ESTRONE; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LEPTIN; LIPID; RNF139 PROTEIN, HUMAN; STEROL REGULATORY ELEMENT BINDING PROTEIN; VBP1 PROTEIN, HUMAN;

EID: 77951642773     PISSN: 0065230X     EISSN: 21625557     Source Type: Book Series    
DOI: 10.1016/S0065-230X(10)07002-8     Document Type: Chapter
Times cited : (42)

References (93)
  • 2
    • 23844527189 scopus 로고    scopus 로고
    • Mechanism of von Hippel-Lindau protein-mediated suppression of nuclear factor kappa B activity
    • An, J., Rettig, M.B., Mechanism of von Hippel-Lindau protein-mediated suppression of nuclear factor kappa B activity. Mol. Cell. Biol. 25 (2005), 7546–7556.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7546-7556
    • An, J.1    Rettig, M.B.2
  • 3
    • 0033747214 scopus 로고    scopus 로고
    • Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways
    • Attoub, S., Noe, V., Pirola, L., Bruyneel, E., Chastre, E., Mareel, M., Wymann, M.P., Gespach, C., Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. FASEB J. 14 (2000), 2329–2338.
    • (2000) FASEB J. , vol.14 , pp. 2329-2338
    • Attoub, S.1    Noe, V.2    Pirola, L.3    Bruyneel, E.4    Chastre, E.5    Mareel, M.6    Wymann, M.P.7    Gespach, C.8
  • 5
    • 38449122032 scopus 로고    scopus 로고
    • Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys
    • Baba, M., Furihata, M., Hong, S.B., Tessarollo, L., Haines, D.C., Southon, E., Patel, V., Igarashi, P., Alvord, W.G., Leighty, R., et al. Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J. Natl. Cancer Inst. 100 (2008), 140–154.
    • (2008) J. Natl. Cancer Inst. , vol.100 , pp. 140-154
    • Baba, M.1    Furihata, M.2    Hong, S.B.3    Tessarollo, L.4    Haines, D.C.5    Southon, E.6    Patel, V.7    Igarashi, P.8    Alvord, W.G.9    Leighty, R.10
  • 6
    • 68149179580 scopus 로고    scopus 로고
    • Adiponectin immunohistochemical expression in colorectal cancer and its correlation with histological grade and tumour microvessel density
    • Barresi, V., Tuccari, G., Barresi, G., Adiponectin immunohistochemical expression in colorectal cancer and its correlation with histological grade and tumour microvessel density. Pathology 41 (2009), 533–538.
    • (2009) Pathology , vol.41 , pp. 533-538
    • Barresi, V.1    Tuccari, G.2    Barresi, G.3
  • 7
    • 0018308131 scopus 로고
    • Characterization and regulation of reductase kinase, a protein kinase that modulates the enzymic activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    • Beg, Z.H., Stonik, J.A., Brewer, H.B. Jr., Characterization and regulation of reductase kinase, a protein kinase that modulates the enzymic activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proc. Natl. Acad. Sci. USA 76 (1979), 4375–4379.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4375-4379
    • Beg, Z.H.1    Stonik, J.A.2    Brewer, H.B.3
  • 8
    • 33746457002 scopus 로고    scopus 로고
    • PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migration
    • Bergmann, S., Junker, K., Henklein, P., Hollenberg, M.D., Settmacher, U., Kaufmann, R., PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migration. Oncol. Rep. 15 (2006), 889–893.
    • (2006) Oncol. Rep. , vol.15 , pp. 889-893
    • Bergmann, S.1    Junker, K.2    Henklein, P.3    Hollenberg, M.D.4    Settmacher, U.5    Kaufmann, R.6
  • 9
    • 0032538875 scopus 로고    scopus 로고
    • Leptin, the product of Ob gene, promotes angiogenesis
    • Bouloumie, A., Drexler, H.C., Lafontan, M., Busse, R., Leptin, the product of Ob gene, promotes angiogenesis. Circ. Res. 83 (1998), 1059–1066.
    • (1998) Circ. Res. , vol.83 , pp. 1059-1066
    • Bouloumie, A.1    Drexler, H.C.2    Lafontan, M.3    Busse, R.4
  • 12
    • 67649435592 scopus 로고    scopus 로고
    • Dietary fat and risk of renal cell carcinoma in the USA: A case-control study
    • Brock, K.E., Gridley, G., Chiu, B.C., Ershow, A.G., Lynch, C.F., Cantor, K.P., Dietary fat and risk of renal cell carcinoma in the USA: A case-control study. Br. J. Nutr. 101 (2009), 1228–1238.
    • (2009) Br. J. Nutr. , vol.101 , pp. 1228-1238
    • Brock, K.E.1    Gridley, G.2    Chiu, B.C.3    Ershow, A.G.4    Lynch, C.F.5    Cantor, K.P.6
  • 13
    • 0041920901 scopus 로고    scopus 로고
    • TSC2 regulates VEGF through mTOR-dependent and -independent pathways
    • Brugarolas, J.B., Vazquez, F., Reddy, A., Sellers, W.R., Kaelin, W.G. Jr., TSC2 regulates VEGF through mTOR-dependent and -independent pathways. Cancer Cell 4 (2003), 147–158.
    • (2003) Cancer Cell , vol.4 , pp. 147-158
    • Brugarolas, J.B.1    Vazquez, F.2    Reddy, A.3    Sellers, W.R.4    Kaelin, W.G.5
  • 14
    • 33744965091 scopus 로고    scopus 로고
    • Attenuation of peroxisome proliferator-activated receptor gamma (PPARgamma) mediates gastrin-stimulated colorectal cancer cell proliferation
    • Chang, A.J., Song, D.H., Wolfe, M.M., Attenuation of peroxisome proliferator-activated receptor gamma (PPARgamma) mediates gastrin-stimulated colorectal cancer cell proliferation. J. Biol. Chem. 281 (2006), 14700–14710.
    • (2006) J. Biol. Chem. , vol.281 , pp. 14700-14710
    • Chang, A.J.1    Song, D.H.2    Wolfe, M.M.3
  • 15
    • 67650032647 scopus 로고    scopus 로고
    • Acyl-coenzyme A:cholesterol acyltransferases
    • Chang, T.Y., Li, B.L., Chang, C.C., Urano, Y., Acyl-coenzyme A:cholesterol acyltransferases. Am. J. Physiol. 297 (2009), E1–E9.
    • (2009) Am. J. Physiol. , vol.297 , pp. E1-E9
    • Chang, T.Y.1    Li, B.L.2    Chang, C.C.3    Urano, Y.4
  • 17
    • 55349114046 scopus 로고    scopus 로고
    • Contemporary epidemiology of renal cell cancer
    • Chow, W.H., Devesa, S.S., Contemporary epidemiology of renal cell cancer. Cancer J. (Sudbury, MA) 14 (2008), 288–301.
    • (2008) Cancer J. (Sudbury, MA) , vol.14 , pp. 288-301
    • Chow, W.H.1    Devesa, S.S.2
  • 18
    • 54749126267 scopus 로고    scopus 로고
    • A novel gene expression profile in lymphatics associated with tumor growth and nodal metastasis
    • Clasper, S., Royston, D., Baban, D., Cao, Y., Ewers, S., Butz, S., Vestweber, D., Jackson, D.G., A novel gene expression profile in lymphatics associated with tumor growth and nodal metastasis. Cancer Res. 68 (2008), 7293–7303.
    • (2008) Cancer Res. , vol.68 , pp. 7293-7303
    • Clasper, S.1    Royston, D.2    Baban, D.3    Cao, Y.4    Ewers, S.5    Butz, S.6    Vestweber, D.7    Jackson, D.G.8
  • 19
    • 55249083994 scopus 로고    scopus 로고
    • Epidemiology, clinical staging, and presentation of renal cell carcinoma
    • vi
    • Decastro, G.J., McKiernan, J.M., Epidemiology, clinical staging, and presentation of renal cell carcinoma. Urol. Clin. North Am. 35 (2008), 581–592 vi.
    • (2008) Urol. Clin. North Am. , vol.35 , pp. 581-592
    • Decastro, G.J.1    McKiernan, J.M.2
  • 21
    • 33751276007 scopus 로고    scopus 로고
    • Mechanisms regulating energy metabolism by adiponectin in obesity and diabetes
    • Fang, X., Sweeney, G., Mechanisms regulating energy metabolism by adiponectin in obesity and diabetes. Biochem. Soc. Trans. 34 (2006), 798–801.
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 798-801
    • Fang, X.1    Sweeney, G.2
  • 22
    • 35848935201 scopus 로고    scopus 로고
    • Cause-specific excess deaths associated with underweight, overweight, and obesity
    • Flegal, K.M., Graubard, B.I., Williamson, D.F., Gail, M.H., Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA 298 (2007), 2028–2037.
    • (2007) JAMA , vol.298 , pp. 2028-2037
    • Flegal, K.M.1    Graubard, B.I.2    Williamson, D.F.3    Gail, M.H.4
  • 26
    • 19644382238 scopus 로고    scopus 로고
    • Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5
    • Gemmill, R.M., Lee, J.P., Chamovitz, D.A., Segal, D., Hooper, J.E., Drabkin, H.A., Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5. Oncogene 24 (2005), 3503–3511.
    • (2005) Oncogene , vol.24 , pp. 3503-3511
    • Gemmill, R.M.1    Lee, J.P.2    Chamovitz, D.A.3    Segal, D.4    Hooper, J.E.5    Drabkin, H.A.6
  • 28
    • 68949198890 scopus 로고    scopus 로고
    • The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma
    • Gimelli, S., Beri, S., Drabkin, H.A., Gambini, C., Gregorio, A., Fiorio, P., Zuffardi, O., Gemmill, R.M., Giorda, R., Gimelli, G., The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma. Mol. Cancer, 8, 2009, 52.
    • (2009) Mol. Cancer , vol.8 , pp. 52
    • Gimelli, S.1    Beri, S.2    Drabkin, H.A.3    Gambini, C.4    Gregorio, A.5    Fiorio, P.6    Zuffardi, O.7    Gemmill, R.M.8    Giorda, R.9    Gimelli, G.10
  • 30
    • 34848861463 scopus 로고    scopus 로고
    • The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
    • Greer, E.L., Oskoui, P.R., Banko, M.R., Maniar, J.M., Gygi, M.P., Gygi, S.P., Brunet, A., The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J. Biol. Chem. 282 (2007), 30107–30119.
    • (2007) J. Biol. Chem. , vol.282 , pp. 30107-30119
    • Greer, E.L.1    Oskoui, P.R.2    Banko, M.R.3    Maniar, J.M.4    Gygi, M.P.5    Gygi, S.P.6    Brunet, A.7
  • 31
    • 39149089305 scopus 로고    scopus 로고
    • Adiponectin: An update
    • Guerre-Millo, M., Adiponectin: An update. Diabetes Metab. 34 (2008), 12–18.
    • (2008) Diabetes Metab. , vol.34 , pp. 12-18
    • Guerre-Millo, M.1
  • 34
    • 33748098353 scopus 로고    scopus 로고
    • Increased serum leptin levels and over expression of leptin receptors are associated with the invasion and progression of renal cell carcinoma
    • Horiguchi, A., Sumitomo, M., Asakuma, J., Asano, T., Zheng, R., Asano, T., Nanus, D.M., Hayakawa, M., Increased serum leptin levels and over expression of leptin receptors are associated with the invasion and progression of renal cell carcinoma. J. Urol. 176 (2006), 1631–1635.
    • (2006) J. Urol. , vol.176 , pp. 1631-1635
    • Horiguchi, A.1    Sumitomo, M.2    Asakuma, J.3    Asano, T.4    Zheng, R.5    Asano, T.6    Nanus, D.M.7    Hayakawa, M.8
  • 35
    • 33748260187 scopus 로고    scopus 로고
    • Leptin promotes invasiveness of murine renal cancer cells via extracellular signal-regulated kinases and rho dependent pathway
    • Horiguchi, A., Sumitomo, M., Asakuma, J., Asano, T., Zheng, R., Asano, T., Nanus, D.M., Hayakawa, M., Leptin promotes invasiveness of murine renal cancer cells via extracellular signal-regulated kinases and rho dependent pathway. J. Urol. 176 (2006), 1636–1641.
    • (2006) J. Urol. , vol.176 , pp. 1636-1641
    • Horiguchi, A.1    Sumitomo, M.2    Asakuma, J.3    Asano, T.4    Zheng, R.5    Asano, T.6    Nanus, D.M.7    Hayakawa, M.8
  • 36
    • 40349114235 scopus 로고    scopus 로고
    • Decreased serum adiponectin levels in patients with metastatic renal cell carcinoma
    • Horiguchi, A., Ito, K., Sumitomo, M., Kimura, F., Asano, T., Hayakawa, M., Decreased serum adiponectin levels in patients with metastatic renal cell carcinoma. Jpn J. Clin. Oncol. 38 (2008), 106–111.
    • (2008) Jpn J. Clin. Oncol. , vol.38 , pp. 106-111
    • Horiguchi, A.1    Ito, K.2    Sumitomo, M.3    Kimura, F.4    Asano, T.5    Hayakawa, M.6
  • 37
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton, J.D., Goldstein, J.L., Brown, M.S., SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109 (2002), 1125–1131.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 38
    • 0030298339 scopus 로고    scopus 로고
    • Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein
    • Hua, X., Nohturfft, A., Goldstein, J.L., Brown, M.S., Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein. Cell 87 (1996), 415–426.
    • (1996) Cell , vol.87 , pp. 415-426
    • Hua, X.1    Nohturfft, A.2    Goldstein, J.L.3    Brown, M.S.4
  • 39
    • 34447650633 scopus 로고    scopus 로고
    • HIF-2alpha downregulation in the absence of functional VHL is not sufficient for renal cell differentiation
    • Hughes, M.D., Kapllani, E., Alexander, A.E., Burk, R.D., Schoenfeld, A.R., HIF-2alpha downregulation in the absence of functional VHL is not sufficient for renal cell differentiation. Cancer Cell Int., 7, 2007, 13.
    • (2007) Cancer Cell Int. , vol.7 , pp. 13
    • Hughes, M.D.1    Kapllani, E.2    Alexander, A.E.3    Burk, R.D.4    Schoenfeld, A.R.5
  • 40
    • 23644448721 scopus 로고    scopus 로고
    • HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
    • Isaacs, J.S., Jung, Y.J., Mole, D.R., Lee, S., Torres-Cabala, C., Chung, Y.L., Merino, M., Trepel, J., Zbar, B., Toro, J., et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability. Cancer Cell 8 (2005), 143–153.
    • (2005) Cancer Cell , vol.8 , pp. 143-153
    • Isaacs, J.S.1    Jung, Y.J.2    Mole, D.R.3    Lee, S.4    Torres-Cabala, C.5    Chung, Y.L.6    Merino, M.7    Trepel, J.8    Zbar, B.9    Toro, J.10
  • 41
    • 34547580169 scopus 로고    scopus 로고
    • Possible role for intracellular cholesteryl ester transfer protein in adipocyte lipid metabolism and storage
    • Izem, L., Morton, R.E., Possible role for intracellular cholesteryl ester transfer protein in adipocyte lipid metabolism and storage. J. Biol. Chem. 282 (2007), 21856–21865.
    • (2007) J. Biol. Chem. , vol.282 , pp. 21856-21865
    • Izem, L.1    Morton, R.E.2
  • 43
    • 4644363095 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene and kidney cancer
    • Kaelin, W.G. Jr., The von Hippel-Lindau tumor suppressor gene and kidney cancer. Clin. Cancer Res. 10 (2004), 6290S–6295S.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6290S-6295S
    • Kaelin, W.G.1
  • 44
    • 33746427905 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein: Roles in cancer and oxygen sensing
    • Kaelin, W.G., The von Hippel-Lindau tumor suppressor protein: Roles in cancer and oxygen sensing. Cold Spring Harb. Symp. Quant. Biol. 70 (2005), 159–166.
    • (2005) Cold Spring Harb. Symp. Quant. Biol. , vol.70 , pp. 159-166
    • Kaelin, W.G.1
  • 45
    • 34249855928 scopus 로고    scopus 로고
    • Interaction between sterol regulatory element-binding proteins and liver receptor homolog-1 reciprocally suppresses their transcriptional activities
    • Kanayama, T., Arito, M., So, K., Hachimura, S., Inoue, J., Sato, R., Interaction between sterol regulatory element-binding proteins and liver receptor homolog-1 reciprocally suppresses their transcriptional activities. J. Biol. Chem. 282 (2007), 10290–10298.
    • (2007) J. Biol. Chem. , vol.282 , pp. 10290-10298
    • Kanayama, T.1    Arito, M.2    So, K.3    Hachimura, S.4    Inoue, J.5    Sato, R.6
  • 46
    • 33645978389 scopus 로고    scopus 로고
    • Expression of hypoxia inducible factor-1alpha and 2alpha in genetically distinct early renal cortical tumors
    • Kim, C.M., Vocke, C., Torres-Cabala, C., Yang, Y., Schmidt, L., Walther, M., Linehan, W.M., Expression of hypoxia inducible factor-1alpha and 2alpha in genetically distinct early renal cortical tumors. J. Urol. 175 (2006), 1908–1914.
    • (2006) J. Urol. , vol.175 , pp. 1908-1914
    • Kim, C.M.1    Vocke, C.2    Torres-Cabala, C.3    Yang, Y.4    Schmidt, L.5    Walther, M.6    Linehan, W.M.7
  • 47
    • 20944443083 scopus 로고    scopus 로고
    • Identification of the promoter region required for human adiponectin gene transcription: Association with CCAAT/enhancer binding protein-beta and tumor necrosis factor-alpha
    • Kita, A., Yamasaki, H., Kuwahara, H., Moriuchi, A., Fukushima, K., Kobayashi, M., Fukushima, T., Takahashi, R., Abiru, N., Uotani, S., et al. Identification of the promoter region required for human adiponectin gene transcription: Association with CCAAT/enhancer binding protein-beta and tumor necrosis factor-alpha. Biochem. Biophys. Res. Commun. 331 (2005), 484–490.
    • (2005) Biochem. Biophys. Res. Commun. , vol.331 , pp. 484-490
    • Kita, A.1    Yamasaki, H.2    Kuwahara, H.3    Moriuchi, A.4    Fukushima, K.5    Kobayashi, M.6    Fukushima, T.7    Takahashi, R.8    Abiru, N.9    Uotani, S.10
  • 48
    • 69249135876 scopus 로고    scopus 로고
    • Obesity and renal cell carcinoma: Epidemiology, underlying mechanisms and management considerations
    • Klinghoffer, Z., Yang, B., Kapoor, A., Pinthus, J.H., Obesity and renal cell carcinoma: Epidemiology, underlying mechanisms and management considerations. Expert Rev. Anticancer Ther. 9 (2009), 975–987.
    • (2009) Expert Rev. Anticancer Ther. , vol.9 , pp. 975-987
    • Klinghoffer, Z.1    Yang, B.2    Kapoor, A.3    Pinthus, J.H.4
  • 49
    • 33846013601 scopus 로고    scopus 로고
    • Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78
    • Lee, J.N., Song, B., DeBose-Boyd, R.A., Ye, J., Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78. J. Biol. Chem. 281 (2006), 39308–39315.
    • (2006) J. Biol. Chem. , vol.281 , pp. 39308-39315
    • Lee, J.N.1    Song, B.2    DeBose-Boyd, R.A.3    Ye, J.4
  • 50
    • 75149146624 scopus 로고    scopus 로고
    • TRC8 is sterol regulated and interacts with lipid and protein biosynthetic pathways
    • Lee, J., Brauweiler, A., Rudolph, M., Hooper, J.E., Drabkin, H.A., Gemmill, R.M., TRC8 is sterol regulated and interacts with lipid and protein biosynthetic pathways. Mol. Cancer Res. 8:1 (2010), 93–106.
    • (2010) Mol. Cancer Res. , vol.8 , Issue.1 , pp. 93-106
    • Lee, J.1    Brauweiler, A.2    Rudolph, M.3    Hooper, J.E.4    Drabkin, H.A.5    Gemmill, R.M.6
  • 51
    • 34547174217 scopus 로고    scopus 로고
    • Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations
    • Li, L., Zhang, L., Zhang, X., Yan, Q., Minamishima, Y.A., Olumi, A.F., Mao, M., Bartz, S., Kaelin, W.G. Jr., Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations. Mol. Cell. Biol. 27 (2007), 5381–5392.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 5381-5392
    • Li, L.1    Zhang, L.2    Zhang, X.3    Yan, Q.4    Minamishima, Y.A.5    Olumi, A.F.6    Mao, M.7    Bartz, S.8    Kaelin, W.G.9
  • 53
    • 33750499711 scopus 로고    scopus 로고
    • The epidemiology of renal cell carcinoma
    • Lipworth, L., Tarone, R.E., McLaughlin, J.K., The epidemiology of renal cell carcinoma. J. Urol. 176 (2006), 2353–2358.
    • (2006) J. Urol. , vol.176 , pp. 2353-2358
    • Lipworth, L.1    Tarone, R.E.2    McLaughlin, J.K.3
  • 55
    • 38849138585 scopus 로고    scopus 로고
    • Expression of two isozymes of acyl-coenzyme A: Cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma
    • Matsumoto, K., Fujiwara, Y., Nagai, R., Yoshida, M., Ueda, S., Expression of two isozymes of acyl-coenzyme A: Cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma. Int. J. Urol. 15 (2008), 166–170.
    • (2008) Int. J. Urol. , vol.15 , pp. 166-170
    • Matsumoto, K.1    Fujiwara, Y.2    Nagai, R.3    Yoshida, M.4    Ueda, S.5
  • 56
    • 33747593550 scopus 로고    scopus 로고
    • Collagenase-2 and -3 mediate epidermal growth factor receptor transactivation by bradykinin B2 receptor in kidney cells
    • Mukhin, Y.V., Gooz, M., Raymond, J.R., Garnovskaya, M.N., Collagenase-2 and -3 mediate epidermal growth factor receptor transactivation by bradykinin B2 receptor in kidney cells. J. Pharmacol. Exp. Ther. 318 (2006), 1033–1043.
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 1033-1043
    • Mukhin, Y.V.1    Gooz, M.2    Raymond, J.R.3    Garnovskaya, M.N.4
  • 57
    • 0000939691 scopus 로고    scopus 로고
    • Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome
    • Nickerson, M.L., Warren, M.B., Toro, J.R., Matrosova, V., Glenn, G., Turner, M.L., Duray, P., Merino, M., Choyke, P., Pavlovich, C.P., et al. Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome. Cancer Cell 2 (2002), 157–164.
    • (2002) Cancer Cell , vol.2 , pp. 157-164
    • Nickerson, M.L.1    Warren, M.B.2    Toro, J.R.3    Matrosova, V.4    Glenn, G.5    Turner, M.L.6    Duray, P.7    Merino, M.8    Choyke, P.9    Pavlovich, C.P.10
  • 58
    • 0030472004 scopus 로고    scopus 로고
    • Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines
    • Nohturfft, A., Hua, X., Brown, M.S., Goldstein, J.L., Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines. Proc. Natl. Acad. Sci. USA 93 (1996), 13709–13714.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13709-13714
    • Nohturfft, A.1    Hua, X.2    Brown, M.S.3    Goldstein, J.L.4
  • 59
    • 0035941291 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase. C
    • Okuda, H., Saitoh, K., Hirai, S., Iwai, K., Takaki, Y., Baba, M., Minato, N., Ohno, S., Shuin, T., The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase. C. J. Biol. Chem. 276 (2001), 43611–43617.
    • (2001) J. Biol. Chem. , vol.276 , pp. 43611-43617
    • Okuda, H.1    Saitoh, K.2    Hirai, S.3    Iwai, K.4    Takaki, Y.5    Baba, M.6    Minato, N.7    Ohno, S.8    Shuin, T.9
  • 60
    • 0346463030 scopus 로고    scopus 로고
    • Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells
    • Ouchi, N., Kobayashi, H., Kihara, S., Kumada, M., Sato, K., Inoue, T., Funahashi, T., Walsh, K., Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J. Biol. Chem. 279 (2004), 1304–1309.
    • (2004) J. Biol. Chem. , vol.279 , pp. 1304-1309
    • Ouchi, N.1    Kobayashi, H.2    Kihara, S.3    Kumada, M.4    Sato, K.5    Inoue, T.6    Funahashi, T.7    Walsh, K.8
  • 61
    • 70350370454 scopus 로고    scopus 로고
    • Signaling through cholesterol esterification: A new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion
    • Paillasse, M.R., de Medina, P., Amouroux, G., Mhamdi, L., Poirot, M., Silvente-Poirot, S., Signaling through cholesterol esterification: A new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion. J. Lipid Res. 50 (2009), 2203–2211.
    • (2009) J. Lipid Res. , vol.50 , pp. 2203-2211
    • Paillasse, M.R.1    de Medina, P.2    Amouroux, G.3    Mhamdi, L.4    Poirot, M.5    Silvente-Poirot, S.6
  • 62
    • 67650760958 scopus 로고    scopus 로고
    • Epidemiology of kidney cancer
    • 782381
    • Pascual, D., Borque, A., Epidemiology of kidney cancer. Adv. Urol., 2008 782381.
    • (2008) Adv. Urol.
    • Pascual, D.1    Borque, A.2
  • 65
    • 34547092923 scopus 로고    scopus 로고
    • A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma
    • Poland, K.S., Azim, M., Folsom, M., Goldfarb, R., Naeem, R., Korch, C., Drabkin, H.A., Gemmill, R.M., Plon, S.E., A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma. Genes Chromosomes Cancer 46 (2007), 805–812.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 805-812
    • Poland, K.S.1    Azim, M.2    Folsom, M.3    Goldfarb, R.4    Naeem, R.5    Korch, C.6    Drabkin, H.A.7    Gemmill, R.M.8    Plon, S.E.9
  • 66
  • 68
    • 0031301274 scopus 로고    scopus 로고
    • Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
    • Rawson, R.B., Zelenski, N.G., Nijhawan, D., Ye, J., Sakai, J., Hasan, M.T., Chang, T.Y., Brown, M.S., Goldstein, J.L., Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs. Mol. Cell 1 (1997), 47–57.
    • (1997) Mol. Cell , vol.1 , pp. 47-57
    • Rawson, R.B.1    Zelenski, N.G.2    Nijhawan, D.3    Ye, J.4    Sakai, J.5    Hasan, M.T.6    Chang, T.Y.7    Brown, M.S.8    Goldstein, J.L.9
  • 69
    • 37049013701 scopus 로고    scopus 로고
    • Cancer incidence and mortality in relation to body mass index in the Million Women Study: Cohort study
    • Reeves, G.K., Pirie, K., Beral, V., Green, J., Spencer, E., Bull, D., Cancer incidence and mortality in relation to body mass index in the Million Women Study: Cohort study. BMJ (Clinical Research ed.), 335, 2007, 1134.
    • (2007) BMJ (Clinical Research ed.) , vol.335 , pp. 1134
    • Reeves, G.K.1    Pirie, K.2    Beral, V.3    Green, J.4    Spencer, E.5    Bull, D.6
  • 71
    • 33646140913 scopus 로고    scopus 로고
    • p53 stabilization and transactivation by a von Hippel-Lindau protein
    • Roe, J.S., Kim, H., Lee, S.M., Kim, S.T., Cho, E.J., Youn, H.D., p53 stabilization and transactivation by a von Hippel-Lindau protein. Mol. Cell 22 (2006), 395–405.
    • (2006) Mol. Cell , vol.22 , pp. 395-405
    • Roe, J.S.1    Kim, H.2    Lee, S.M.3    Kim, S.T.4    Cho, E.J.5    Youn, H.D.6
  • 72
    • 33644983700 scopus 로고    scopus 로고
    • Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young
    • Rowley, C.W., Staloch, L.J., Divine, J.K., McCaul, S.P., Simon, T.C., Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young. Am. J. Physiol. Gastrointest. Liver Physiol. 290 (2006), G466–G475.
    • (2006) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.290 , pp. G466-G475
    • Rowley, C.W.1    Staloch, L.J.2    Divine, J.K.3    McCaul, S.P.4    Simon, T.C.5
  • 73
    • 0032185770 scopus 로고    scopus 로고
    • Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
    • Sakai, J., Rawson, R.B., Espenshade, P.J., Cheng, D., Seegmiller, A.C., Goldstein, J.L., Brown, M.S., Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells. Mol. Cell 2 (1998), 505–514.
    • (1998) Mol. Cell , vol.2 , pp. 505-514
    • Sakai, J.1    Rawson, R.B.2    Espenshade, P.J.3    Cheng, D.4    Seegmiller, A.C.5    Goldstein, J.L.6    Brown, M.S.7
  • 75
    • 0028360111 scopus 로고
    • Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1)
    • Sato, R., Yang, J., Wang, X., Evans, M.J., Ho, Y.K., Goldstein, J.L., Brown, M.S., Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J. Biol. Chem. 269 (1994), 17267–17273.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17267-17273
    • Sato, R.1    Yang, J.2    Wang, X.3    Evans, M.J.4    Ho, Y.K.5    Goldstein, J.L.6    Brown, M.S.7
  • 76
    • 47249133453 scopus 로고    scopus 로고
    • Biphasic regulation of HMG-CoA reductase expression and activity during wound healing and its functional role in the control of keratinocyte angiogenic and proliferative responses
    • Schiefelbein, D., Goren, I., Fisslthaler, B., Schmidt, H., Geisslinger, G., Pfeilschifter, J., Frank, S., Biphasic regulation of HMG-CoA reductase expression and activity during wound healing and its functional role in the control of keratinocyte angiogenic and proliferative responses. J. Biol. Chem. 283 (2008), 15479–15490.
    • (2008) J. Biol. Chem. , vol.283 , pp. 15479-15490
    • Schiefelbein, D.1    Goren, I.2    Fisslthaler, B.3    Schmidt, H.4    Geisslinger, G.5    Pfeilschifter, J.6    Frank, S.7
  • 77
    • 2542419773 scopus 로고    scopus 로고
    • Adipocyte determination- and differentiation-dependent factor 1/sterol regulatory element-binding protein 1c regulates mouse adiponectin expression
    • Seo, J.B., Moon, H.M., Noh, M.J., Lee, Y.S., Jeong, H.W., Yoo, E.J., Kim, W.S., Park, J., Youn, B.S., Kim, J.W., et al. Adipocyte determination- and differentiation-dependent factor 1/sterol regulatory element-binding protein 1c regulates mouse adiponectin expression. J. Biol. Chem. 279 (2004), 22108–22117.
    • (2004) J. Biol. Chem. , vol.279 , pp. 22108-22117
    • Seo, J.B.1    Moon, H.M.2    Noh, M.J.3    Lee, Y.S.4    Jeong, H.W.5    Yoo, E.J.6    Kim, W.S.7    Park, J.8    Youn, B.S.9    Kim, J.W.10
  • 79
    • 67749111502 scopus 로고    scopus 로고
    • The LKB1–AMPK pathway: Metabolism and growth control in tumour suppression
    • Shackelford, D.B., Shaw, R.J., The LKB1–AMPK pathway: Metabolism and growth control in tumour suppression. Nat. Rev. 9 (2009), 563–575.
    • (2009) Nat. Rev. , vol.9 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 80
    • 48949115069 scopus 로고    scopus 로고
    • Rapamycin down-regulates LDL-receptor expression independently of SREBP-2
    • Sharpe, L.J., Brown, A.J., Rapamycin down-regulates LDL-receptor expression independently of SREBP-2. Biochem. Biophys. Res. Commun. 373 (2008), 670–674.
    • (2008) Biochem. Biophys. Res. Commun. , vol.373 , pp. 670-674
    • Sharpe, L.J.1    Brown, A.J.2
  • 83
    • 58149161720 scopus 로고    scopus 로고
    • PPARgamma, PTEN, and the Fight against Cancer
    • 932632
    • Teresi, R.E., Waite, K.A., PPARgamma, PTEN, and the Fight against Cancer. PPAR Res., 2008, 2008 932632.
    • (2008) PPAR Res. , vol.2008
    • Teresi, R.E.1    Waite, K.A.2
  • 85
    • 24044552365 scopus 로고    scopus 로고
    • Evaluation of the lipid composition of human healthy and neoplastic renal tissues
    • Tugnoli, V., Trinchero, A., Tosi, M.R., Evaluation of the lipid composition of human healthy and neoplastic renal tissues. Ital. J. Biochem. 53 (2004), 169–182.
    • (2004) Ital. J. Biochem. , vol.53 , pp. 169-182
    • Tugnoli, V.1    Trinchero, A.2    Tosi, M.R.3
  • 86
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • Yang, T., Espenshade, P.J., Wright, M.E., Yabe, D., Gong, Y., Aebersold, R., Goldstein, J.L., Brown, M.S., Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110 (2002), 489–500.
    • (2002) Cell , vol.110 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6    Goldstein, J.L.7    Brown, M.S.8
  • 88
    • 33751501966 scopus 로고    scopus 로고
    • Activation of sterol regulatory element-binding proteins (SREBPs) is critical in IL-8-induced angiogenesis
    • Yao, M., Zhou, R.H., Petreaca, M., Zheng, L., Shyy, J., Martins-Green, M., Activation of sterol regulatory element-binding proteins (SREBPs) is critical in IL-8-induced angiogenesis. J. Leukoc. Biol. 80 (2006), 608–620.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 608-620
    • Yao, M.1    Zhou, R.H.2    Petreaca, M.3    Zheng, L.4    Shyy, J.5    Martins-Green, M.6
  • 89
    • 0027490174 scopus 로고
    • SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
    • Yokoyama, C., Wang, X., Briggs, M.R., Admon, A., Wu, J., Hua, X., Goldstein, J.L., Brown, M.S., SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell 75 (1993), 187–197.
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8
  • 90
    • 34548814981 scopus 로고    scopus 로고
    • Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells
    • Yoon, S., Lee, M.Y., Park, S.W., Moon, J.S., Koh, Y.K., Ahn, Y.H., Park, B.W., Kim, K.S., Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells. J. Biol. Chem. 282 (2007), 26122–26131.
    • (2007) J. Biol. Chem. , vol.282 , pp. 26122-26131
    • Yoon, S.1    Lee, M.Y.2    Park, S.W.3    Moon, J.S.4    Koh, Y.K.5    Ahn, Y.H.6    Park, B.W.7    Kim, K.S.8
  • 91
    • 0034493849 scopus 로고    scopus 로고
    • Changes in free and esterified cholesterol: Hallmarks of acute renal tubular injury and acquired cytoresistance
    • Zager, R.A., Kalhorn, T.F., Changes in free and esterified cholesterol: Hallmarks of acute renal tubular injury and acquired cytoresistance. Am. J. Pathol. 157 (2000), 1007–1016.
    • (2000) Am. J. Pathol. , vol.157 , pp. 1007-1016
    • Zager, R.A.1    Kalhorn, T.F.2


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