메뉴 건너뛰기




Volumn 176, Issue 4, 2006, Pages 1636-1641

Leptin Promotes Invasiveness of Murine Renal Cancer Cells Via Extracellular Signal-Regulated Kinases and Rho Dependent Pathway

Author keywords

kidney; kidney neoplasms; neoplasm invasiveness; obesity

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; LEPTIN; LEPTIN RECEPTOR; MATRIGEL; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE;

EID: 33748260187     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2006.06.040     Document Type: Article
Times cited : (40)

References (20)
  • 2
    • 0033782028 scopus 로고    scopus 로고
    • Leptin in the regulation of immunity, inflammation, and hematopoiesis
    • Fantuzzi G., and Faggioni R. Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol 68 (2000) 437
    • (2000) J Leukoc Biol , vol.68 , pp. 437
    • Fantuzzi, G.1    Faggioni, R.2
  • 3
    • 0033862589 scopus 로고    scopus 로고
    • Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair
    • Frank S., Stallmeyer B., Kampfer H., Kolb N., and Pfeilschifter J. Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair. J Clin Invest 106 (2000) 501
    • (2000) J Clin Invest , vol.106 , pp. 501
    • Frank, S.1    Stallmeyer, B.2    Kampfer, H.3    Kolb, N.4    Pfeilschifter, J.5
  • 5
    • 0035973147 scopus 로고    scopus 로고
    • Potential role of leptin in angiogenesis. leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
    • Park H.Y., Kwon H.M., Lim H.J., Hong B.K., Lee J.Y., Park B.E., et al. Potential role of leptin in angiogenesis. leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exp Mol Med 33 (2001) 95
    • (2001) Exp Mol Med , vol.33 , pp. 95
    • Park, H.Y.1    Kwon, H.M.2    Lim, H.J.3    Hong, B.K.4    Lee, J.Y.5    Park, B.E.6
  • 6
    • 3042817487 scopus 로고    scopus 로고
    • Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
    • Ishikawa M., Kitayama J., and Nagawa H. Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res 10 (2004) 4325
    • (2004) Clin Cancer Res , vol.10 , pp. 4325
    • Ishikawa, M.1    Kitayama, J.2    Nagawa, H.3
  • 7
    • 11244299831 scopus 로고    scopus 로고
    • Serum insulin-like growth factor-1 is an independent predictor of prognosis in patients with renal cell carcinoma
    • Rasmuson T., Grankvist K., Jacobsen J., Olsson T., and Ljungberg B. Serum insulin-like growth factor-1 is an independent predictor of prognosis in patients with renal cell carcinoma. Acta Oncol 43 (2004) 744
    • (2004) Acta Oncol , vol.43 , pp. 744
    • Rasmuson, T.1    Grankvist, K.2    Jacobsen, J.3    Olsson, T.4    Ljungberg, B.5
  • 8
    • 0037146224 scopus 로고    scopus 로고
    • Leptin-a growth factor in normal and malignant breast cells and for normal mammary gland development
    • Hu X., Juneja S.C., Maihle N.J., and Cleary M.P. Leptin-a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst 94 (2002) 1704
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1704
    • Hu, X.1    Juneja, S.C.2    Maihle, N.J.3    Cleary, M.P.4
  • 9
    • 8544260325 scopus 로고    scopus 로고
    • Leptin induces cell migration and the expression of growth factors in human prostate cancer cells
    • Frankenberry K.A., Somasundar P., McFadden D.W., and Vona-Davis L.C. Leptin induces cell migration and the expression of growth factors in human prostate cancer cells. Am J Surg 188 (2004) 560
    • (2004) Am J Surg , vol.188 , pp. 560
    • Frankenberry, K.A.1    Somasundar, P.2    McFadden, D.W.3    Vona-Davis, L.C.4
  • 10
    • 0141838111 scopus 로고    scopus 로고
    • Transduction of leptin growth signals in placental cells is independent of JAK-STAT activation
    • Cauzac M., Czuba D., Girard J., and Hauguel-de Mouzon S. Transduction of leptin growth signals in placental cells is independent of JAK-STAT activation. Placenta 24 (2003) 378
    • (2003) Placenta , vol.24 , pp. 378
    • Cauzac, M.1    Czuba, D.2    Girard, J.3    Hauguel-de Mouzon, S.4
  • 11
    • 0035864911 scopus 로고    scopus 로고
    • Obesity, hypertension, and renal cancer
    • Yu M.C., and Ross R.K. Obesity, hypertension, and renal cancer. N Engl J Med 344 (2001) 531
    • (2001) N Engl J Med , vol.344 , pp. 531
    • Yu, M.C.1    Ross, R.K.2
  • 12
    • 0036840309 scopus 로고    scopus 로고
    • Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands
    • Goetze S., Bungenstock A., Czupalla C., Eilers F., Stawowy P., Kintscher U., et al. Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands. Hypertension 40 (2002) 748
    • (2002) Hypertension , vol.40 , pp. 748
    • Goetze, S.1    Bungenstock, A.2    Czupalla, C.3    Eilers, F.4    Stawowy, P.5    Kintscher, U.6
  • 13
    • 11144238571 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis
    • Horiguchi A., Sumitomo M., Asakuma J., Asano T., and Hayakawa M. 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis. Clin Cancer Res 10 (2004) 8648
    • (2004) Clin Cancer Res , vol.10 , pp. 8648
    • Horiguchi, A.1    Sumitomo, M.2    Asakuma, J.3    Asano, T.4    Hayakawa, M.5
  • 14
    • 0033747214 scopus 로고    scopus 로고
    • Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways
    • Attoub S., Noe V., Pirola L., Bruyneel E., Chastre E., Mareel M., et al. Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. FASEB J 14 (2000) 2329
    • (2000) FASEB J , vol.14 , pp. 2329
    • Attoub, S.1    Noe, V.2    Pirola, L.3    Bruyneel, E.4    Chastre, E.5    Mareel, M.6
  • 15
    • 0037023720 scopus 로고    scopus 로고
    • Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration
    • Jo M., Thomas K.S., Somlyo A.V., Somlyo A.P., and Gonias S.L. Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration. J Biol Chem 277 (2002) 12479
    • (2002) J Biol Chem , vol.277 , pp. 12479
    • Jo, M.1    Thomas, K.S.2    Somlyo, A.V.3    Somlyo, A.P.4    Gonias, S.L.5
  • 16
    • 0030597308 scopus 로고    scopus 로고
    • Leptin induces tyrosine phosphorylation of cellular proteins including STAT-1 in human renal adenocarcinoma cells, ACHN
    • Takahashi Y., Okimura Y., Mizuno I., Takahashi T., Kaji H., Uchiyama T., et al. Leptin induces tyrosine phosphorylation of cellular proteins including STAT-1 in human renal adenocarcinoma cells, ACHN. Biochem Biophys Res Commun 228 (1996) 859
    • (1996) Biochem Biophys Res Commun , vol.228 , pp. 859
    • Takahashi, Y.1    Okimura, Y.2    Mizuno, I.3    Takahashi, T.4    Kaji, H.5    Uchiyama, T.6
  • 17
    • 0042208455 scopus 로고    scopus 로고
    • Re. Leptin-a growth factor in normal and malignant breast cells and for normal mammary gland development
    • Oelmann E., Haghgu S., Kulimova E., Serve H., Schmitmann C., and Berdel W.E. Re. Leptin-a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst 95 (2003) 1171
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1171
    • Oelmann, E.1    Haghgu, S.2    Kulimova, E.3    Serve, H.4    Schmitmann, C.5    Berdel, W.E.6
  • 18
    • 0038305915 scopus 로고    scopus 로고
    • ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis
    • Brahmbhatt A.A., and Klemke R.L. ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis. J Biol Chem 278 (2003) 13016
    • (2003) J Biol Chem , vol.278 , pp. 13016
    • Brahmbhatt, A.A.1    Klemke, R.L.2
  • 19
    • 0036156469 scopus 로고    scopus 로고
    • Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts
    • Pawlak G., and Helfman D.M. Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts. Mol Biol Cell 13 (2002) 336
    • (2002) Mol Biol Cell , vol.13 , pp. 336
    • Pawlak, G.1    Helfman, D.M.2
  • 20
    • 0642281441 scopus 로고    scopus 로고
    • Subcutaneous interleukin-2 and interferon alfa administration in patients with metastatic renal cell carcinoma. final results of SCAPP III, a large, multicenter, phase II, nonrandomized study with sequential analysis design
    • Subcutaneous Administration Propeukin Program Cooperative Group
    • Tourani J.M., Pfister C., Tubiana N., Ouldkaci M., Prevot G., Lucas V., et al., Subcutaneous Administration Propeukin Program Cooperative Group. Subcutaneous interleukin-2 and interferon alfa administration in patients with metastatic renal cell carcinoma. final results of SCAPP III, a large, multicenter, phase II, nonrandomized study with sequential analysis design. J Clin Oncol 21 (2003) 3987
    • (2003) J Clin Oncol , vol.21 , pp. 3987
    • Tourani, J.M.1    Pfister, C.2    Tubiana, N.3    Ouldkaci, M.4    Prevot, G.5    Lucas, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.