An overview of liposome lyophilization and its future potential

Journal of Controlled Release

Volumn 142, Issue 3, 2010, Pages 299-311

  Chen, Chengjun ^a   Han, Dandan ^a   Cai, Cuifang ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Encapsulated solute drug retention; Gel to liquid crystalline phase transition temperature; Glass transition temperature; Liposome; Lyophilization

Indexed keywords

DRY MASS; EXTRINSIC FACTORS; GLASS TRANSITION TEMPERATURE; KEY FACTORS; LIQUID CRYSTALLINE PHASE TRANSITION; LONG TERM STABILITY; LYOPROTECTANTS; PROCESS PARAMETERS; PROTECTIVE EFFECTS; STORAGE CONDITION; TECHNIQUES USED; TECHNOLOGICAL FACTORS; VESICLE SIZE;

CRYSTALLINE MATERIALS; GELS; GLASS; LIPID BILAYERS; LIPOSOMES; LIQUIDS; PHOSPHOLIPIDS; SUPERCONDUCTING TRANSITION TEMPERATURE;

GLASS TRANSITION;

AMPHOTERICIN B LIPID COMPLEX; DEXTRAN; DEXTRAN 40; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DIOLEOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; DISTEAROYLPHOSPHATIDYLCHOLINE; DOXORUBICIN; DRUG ADDITIVE; GLUCOSE; HETASTARCH; INULIN; LACTOSE; LIPID; LIPOSOME; LYOPROTECTANT; MALTOSE; PHOSPHATIDYLCHOLINE; RAFFINOSE; STABILIZING AGENT; SUCROSE; TREHALOSE; UNCLASSIFIED DRUG;

DRUG CHOICE; DRUG FORMULATION; DRUG RETENTION; DRUG STABILITY; DRUG STORAGE; DRY MASS; FREEZE DRYING; FREEZING; GEL; GLASS TRANSITION TEMPERATURE; LIPID BILAYER; LIQUID; PHASE TRANSITION; PRIORITY JOURNAL; REVIEW; TRANSITION TEMPERATURE; VITRIFICATION;

AMINO ACIDS; CARBOHYDRATES; DRUG STABILITY; FREEZE DRYING; LIPOSOMES; PHARMACEUTICAL PREPARATIONS; PHOSPHOLIPIDS; TECHNOLOGY, PHARMACEUTICAL; WATER;

EID: 77349099478     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.10.024     Document Type: Review

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