Copper-dependent inhibition of cytochrome c oxidase by Aβ 1-42 requires reduced methionine at residue 35 of the Aβ peptide

Journal of Neurochemistry

Volumn 99, Issue 1, 2006, Pages 226-236

  Crouch, Peter J ^a   Barnham, Kevin J ^a,b   Duce, James A ^a   Blake, Rachel E ^a   Masters, Colin L ^a,b   Trounce, Ian A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

Author keywords

Alzheimer's disease; Amyloid ; Copper; Cytochrome c oxidase; Methionine 35; Mitochondria

Indexed keywords

ALANINE; AMYLOID BETA PROTEIN[1-42]; CATALASE; COPPER; CYTOCHROME C OXIDASE; DODECYL SULFATE SODIUM; HYDROGEN PEROXIDE; METHIONINE; SULFOXIDE; SULFUR; TYROSINE; VALINE;

AGING; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ASSAY; ENZYME INHIBITION; ENZYME MECHANISM; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CELLS, CULTURED; COPPER; ELECTRON TRANSPORT COMPLEX IV; HUMANS; LYMPHOCYTES; METHIONINE; MICE; PEPTIDE FRAGMENTS; SUBMITOCHONDRIAL PARTICLES;

EID: 33748684352     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04050.x     Document Type: Article

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