Attenuated cytotoxicity but enhanced βfibril of a mutant amyloid β-peptide with a methionine to cysteine substitution

FEBS Letters

Volumn 581, Issue 7, 2007, Pages 1269-1274

  Dai, Xue Ling ^a   Sun, Ya Xuan ^b   Jiang, Zhao Feng ^b  

^a CAPITAL NORMAL UNIVERSITY   (China)

^b BEIJING UNION UNIVERSITY   (China)

Author keywords

Amyloid peptide; Circular dichroism spectra; Neuronal cell viability; Thioflavin T

Indexed keywords

AMYLOID BETA PROTEIN; COPPER; CYSTEINE; METHIONINE; MUTANT PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BETA SHEET; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; NERVE DEGENERATION; NEUROCHEMISTRY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; SENILE PLAQUE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMYLOID; AMYLOID BETA-PROTEIN; ANIMALS; CELLS, CULTURED; CIRCULAR DICHROISM; CYSTEINE; HUMANS; METHIONINE; MOLECULAR SEQUENCE DATA; NEURONS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; RATS;

EID: 33947390936     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.02.038     Document Type: Article

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