Dynamic characterization of a DNA repair enzyme: NMR studies of [methyl-13C]methionine-labeled DNA polymerase β

Biochemistry

Volumn 43, Issue 28, 2004, Pages 8911-8922

  Bose Basu, Bidisha ^a   DeRose, Eugene F ^a   Kirby, Thomas W ^a   Mueller, Geoffrey A ^a   Beard, William A ^a   Wilson, Samuel H ^a   London, Robert E ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CHEMICAL BONDS; DNA; ENZYMES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CONFORMATIONAL ACTIVATION; OLIGONUCLEOTIDES;

BIOCHEMISTRY;

COBALT; DNA DIRECTED DNA POLYMERASE BETA; METHIONINE DERIVATIVE; METHYLMETHIONINE C 13; OLIGONUCLEOTIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DNA REPAIR; ENZYME ANALYSIS; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ANIMALS; CARBON ISOTOPES; DEOXYCYTOSINE NUCLEOTIDES; DNA POLYMERASE BETA; DNA REPAIR ENZYMES; MOLECULAR STRUCTURE; MOTION; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGONUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RATS;

EID: 3142775571     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049641n     Document Type: Article

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