Obesity and Type 2 diabetes: Slow down!-Can metabolic deceleration protect the islet beta cell from excess nutrient-induced damage?

Molecular and Cellular Endocrinology

Volumn 316, Issue 2, 2010, Pages 140-146

  Andrikopoulos, S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

C57BL 6 mouse; DBA 2 mouse; Endoplasmic reticulum stress; Fat oxidation; Glucose oxidation; Insulin biosynthesis; Metabolic deceleration; Oxidative stress

Indexed keywords

FATTY ACID; FRUCTOSE BISPHOSPHATASE; NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASE;

C57BL 6 MOUSE; CELL FUNCTION; CELL VIABILITY; DBA 2 MOUSE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HUMAN; INSULIN RELEASE; METABOLIC INHIBITION; METABOLIC RATE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRIENT LOADING; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REVIEW; TRANSGENIC MOUSE;

ANIMALS; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM; ENERGY METABOLISM; FATTY ACIDS, NONESTERIFIED; FRUCTOSE-BISPHOSPHATASE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; OBESITY; OXIDATIVE STRESS;

EID: 72449194701     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2009.09.031     Document Type: Review

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