-
1
-
-
0027690207
-
Comparison of trypan blue dye exclusion and fluorometric assays for mammalian cell viability determinations
-
Altman SA, Randers L & Rao G 1993 Comparison of trypan blue dye exclusion and fluorometric assays for mammalian cell viability determinations. Biotechnology Progress 9 671-674.
-
(1993)
Biotechnology Progress
, vol.9
, pp. 671-674
-
-
Altman, S.A.1
Randers, L.2
Rao, G.3
-
2
-
-
0027489148
-
Impaired regulation of hepatic fructose-1,6-bisphosphatase in the New Zealand obese mouse model of NIDDM
-
Andrikopoulos S, Rosella G, Gaskin E, Thorburn A, Kaczmarczyk S, Zajac JD & Proietto J 1993 Impaired regulation of hepatic fructose-1,6-bisphosphatase in the New Zealand obese mouse model of NIDDM. Diabetes 42 1731-1736.
-
(1993)
Diabetes
, vol.42
, pp. 1731-1736
-
-
Andrikopoulos, S.1
Rosella, G.2
Gaskin, E.3
Thorburn, A.4
Kaczmarczyk, S.5
Zajac, J.D.6
Proietto, J.7
-
3
-
-
0033669527
-
β-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes
-
Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T & Kahn SE 2000 β-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes. Diabetes 49 2056-2062.
-
(2000)
Diabetes
, vol.49
, pp. 2056-2062
-
-
Andrikopoulos, S.1
Verchere, C.B.2
Terauchi, Y.3
Kadowaki, T.4
Kahn, S.E.5
-
4
-
-
0017880329
-
Alteration of islet cell populations in spontaneously diabetic mice
-
Baetens D, Stefan Y, Ravazzola M, Malaisse-Lagae F, Coleman DL & Orci L 1978 Alteration of islet cell populations in spontaneously diabetic mice. Diabetes 27 1-7.
-
(1978)
Diabetes
, vol.27
, pp. 1-7
-
-
Baetens, D.1
Stefan, Y.2
Ravazzola, M.3
Malaisse-Lagae, F.4
Coleman, D.L.5
Orci, L.6
-
5
-
-
0026088145
-
Evolution of insulin secretory response to glucose by perifused islets from lean (FA/FA) rats chronically infused with glucose
-
Bedoya FJ & Jeanrenaud B 1991 Evolution of insulin secretory response to glucose by perifused islets from lean (FA/FA) rats chronically infused with glucose. Diabetes 40 7-14.
-
(1991)
Diabetes
, vol.40
, pp. 7-14
-
-
Bedoya, F.J.1
Jeanrenaud, B.2
-
6
-
-
0033623530
-
Glucose-induced [Ca2+]i abnormalities in human pancreatic islets: Important role of overstimulation
-
Bjorklund A, Lansner A & Grill VE 2000 Glucose-induced [Ca2+]i abnormalities in human pancreatic islets: important role of overstimulation. Diabetes 49 1840-1848.
-
(2000)
Diabetes
, vol.49
, pp. 1840-1848
-
-
Bjorklund, A.1
Lansner, A.2
Grill, V.E.3
-
7
-
-
0026033901
-
Abnormal sensitivity to glucose of human islets culture in a high glucose medium: Partial reversibility afer an additional culture in a normal glucose medium
-
Davalli AM, Ricordi G, Socci C, Braghi S, Bertuzzi F, Fattor B, Di Carlo V, Pontiroli AE & Pozza G 1991 Abnormal sensitivity to glucose of human islets culture in a high glucose medium: partial reversibility afer an additional culture in a normal glucose medium. Journal of Clinical Endocrinology and Metabolism 72 202-208.
-
(1991)
Journal of Clinical Endocrinology and Metabolism
, vol.72
, pp. 202-208
-
-
Davalli, A.M.1
Ricordi, G.2
Socci, C.3
Braghi, S.4
Bertuzzi, F.5
Fattor, B.6
Di Carlo, V.7
Pontiroli, A.E.8
Pozza, G.9
-
8
-
-
0026451942
-
Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the β-cell function
-
Eizirik DL, Korbutt GS & Hellerstrom C 1992 Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the β-cell function. Journal of Clinical Investigation 90 1263-1268.
-
(1992)
Journal of Clinical Investigation
, vol.90
, pp. 1263-1268
-
-
Eizirik, D.L.1
Korbutt, G.S.2
Hellerstrom, C.3
-
9
-
-
0028296629
-
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation
-
Eizirik DL, Sandler S, Welsh N, Cetkovic-Cvrlje M, Nieman A, Geller DA, Pipeleers DG, Bendtzen K & Hellerstrom C 1994 Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. Journal of Clinical Investigation 93 1968-1974.
-
(1994)
Journal of Clinical Investigation
, vol.93
, pp. 1968-1974
-
-
Eizirik, D.L.1
Sandler, S.2
Welsh, N.3
Cetkovic-Cvrlje, M.4
Nieman, A.5
Geller, D.A.6
Pipeleers, D.G.7
Bendtzen, K.8
Hellerstrom, C.9
-
10
-
-
0036830463
-
Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy
-
Forbes JM, Cooper ME, Thallas V, Burns WC, Thomas MC, Brammar GC, Lee F, Grant SL, Burrell LA, Jerums G & Osicka TM 2002 Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy. Diabetes 51 3274-3282.
-
(2002)
Diabetes
, vol.51
, pp. 3274-3282
-
-
Forbes, J.M.1
Cooper, M.E.2
Thallas, V.3
Burns, W.C.4
Thomas, M.C.5
Brammar, G.C.6
Lee, F.7
Grant, S.L.8
Burrell, L.A.9
Jerums, G.10
Osicka, T.M.11
-
12
-
-
0026091234
-
Monolayer culture of adult rat pancreatic islets on extracellular matrix: Modulation of B-cell function by chronic exposure to high glucose
-
Kaiser N, Corcos AP, Sarel I & Cerasi E 1991 Monolayer culture of adult rat pancreatic islets on extracellular matrix: modulation of B-cell function by chronic exposure to high glucose. Endocrinology 129 2067-2076.
-
(1991)
Endocrinology
, vol.129
, pp. 2067-2076
-
-
Kaiser, N.1
Corcos, A.P.2
Sarel, I.3
Cerasi, E.4
-
13
-
-
0033431581
-
Induction of glycation suppresses glucokinase gene expression in HIT-T15 cells
-
Kajimoto Y, Matsuoka T, Kaneto H, Watada H, Fujitani Y, Kishimoto M, Sakamoto K, Matsuhisa M, Kawamori R, Yamasaki Y & Hori M 1999 Induction of glycation suppresses glucokinase gene expression in HIT-T15 cells. Diabetologia 42 1417-1424.
-
(1999)
Diabetologia
, vol.42
, pp. 1417-1424
-
-
Kajimoto, Y.1
Matsuoka, T.2
Kaneto, H.3
Watada, H.4
Fujitani, Y.5
Kishimoto, M.6
Sakamoto, K.7
Matsuhisa, M.8
Kawamori, R.9
Yamasaki, Y.10
Hori, M.11
-
14
-
-
0030931645
-
Suppression of transcription factor PDX-1/IPF-1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells
-
Kajimoto Y, Watada H, Matsuoka T, Kaneto H, Fujitani Y, Miyazaki J & Yamasaki Y 1997 Suppression of transcription factor PDX-1/IPF-1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells. Journal of Clinical Investigation 100 1810-1846.
-
(1997)
Journal of Clinical Investigation
, vol.100
, pp. 1810-1846
-
-
Kajimoto, Y.1
Watada, H.2
Matsuoka, T.3
Kaneto, H.4
Fujitani, Y.5
Miyazaki, J.6
Yamasaki, Y.7
-
15
-
-
0033499583
-
Beneficial effects of antioxidants in diabetes. Possible protection of pancreatic β-cells against glucose toxicity
-
Kaneto H, Kajimoto Y, Miyagawa J, Matsuoka T, Fujitani Y, Umayahara T, Matsuzawa Y, Yamasaki Y & Hori M 1999 Beneficial effects of antioxidants in diabetes. Possible protection of pancreatic β-cells against glucose toxicity. Diabetes 48 2398-2406.
-
(1999)
Diabetes
, vol.48
, pp. 2398-2406
-
-
Kaneto, H.1
Kajimoto, Y.2
Miyagawa, J.3
Matsuoka, T.4
Fujitani, Y.5
Umayahara, T.6
Matsuzawa, Y.7
Yamasaki, Y.8
Hori, M.9
-
16
-
-
0036090362
-
Comparison of insulin secretory function in two mouse models with different susceptibility to beta-cell failure
-
Kooptiwut S, Zraika S, Thorburn AW, Dunlop ME, Darwiche R, Kay TW, Proietto J & Andrikopoulos S 2002 Comparison of insulin secretory function in two mouse models with different susceptibility to beta-cell failure. Endocrinology 143 2085-2092.
-
(2002)
Endocrinology
, vol.143
, pp. 2085-2092
-
-
Kooptiwut, S.1
Zraika, S.2
Thorburn, A.W.3
Dunlop, M.E.4
Darwiche, R.5
Kay, T.W.6
Proietto, J.7
Andrikopoulos, S.8
-
17
-
-
0023594954
-
Impaired insulin secretion associated with near normoglycemia
-
Leahy JL, Cooper HE & Weir GC 1987 Impaired insulin secretion associated with near normoglycemia. Diabetes 36 459-464.
-
(1987)
Diabetes
, vol.36
, pp. 459-464
-
-
Leahy, J.L.1
Cooper, H.E.2
Weir, G.C.3
-
18
-
-
0023229614
-
Analysis of differential survival of syngeneic islets transplanted into hyperglycemic C57BL/6J versus C57BL/KsJ mice
-
Leiter EH 1987 Analysis of differential survival of syngeneic islets transplanted into hyperglycemic C57BL/6J versus C57BL/KsJ mice. Transplantation 44 401-406.
-
(1987)
Transplantation
, vol.44
, pp. 401-406
-
-
Leiter, E.H.1
-
19
-
-
0019749949
-
The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex
-
Leiter EH, Coleman DL & Hummel KP 1981 The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex. Diabetes 30 1029-1034.
-
(1981)
Diabetes
, vol.30
, pp. 1029-1034
-
-
Leiter, E.H.1
Coleman, D.L.2
Hummel, K.P.3
-
20
-
-
0028074442
-
Effects of glucose on insulin secretion, glucokinase activity, and transgene expression in transgenic mouse islets containing an upstream glucokinase promoter - Human growth hormone fusion gene
-
Liang Y, Jetton TL, Zimmerman EC, Najafi H, Berner DK, Matschinsky FM & Magnuson MA 1994 Effects of glucose on insulin secretion, glucokinase activity, and transgene expression in transgenic mouse islets containing an upstream glucokinase promoter - human growth hormone fusion gene. Diabetes 43 1138-1145.
-
(1994)
Diabetes
, vol.43
, pp. 1138-1145
-
-
Liang, Y.1
Jetton, T.L.2
Zimmerman, E.C.3
Najafi, H.4
Berner, D.K.5
Matschinsky, F.M.6
Magnuson, M.A.7
-
21
-
-
0029859966
-
Effects of chronically elevated glucose levels on the functional properties of rat pancreatic β-cells
-
Ling Z, Kiekens R, Mahler T, Schuit FC, Pipeleers-Marichal M, Sener A, Kloppel G, Malaisse WJ & Pipeleers DG 1996 Effects of chronically elevated glucose levels on the functional properties of rat pancreatic β-cells. Diabetes 45 1774-1782.
-
(1996)
Diabetes
, vol.45
, pp. 1774-1782
-
-
Ling, Z.1
Kiekens, R.2
Mahler, T.3
Schuit, F.C.4
Pipeleers-Marichal, M.5
Sener, A.6
Kloppel, G.7
Malaisse, W.J.8
Pipeleers, D.G.9
-
22
-
-
0344258475
-
Impaired β-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose
-
Marshak S, Leibowitz G, Bertuzzi F, Socci C, Kaiser N, Gross DJ, Cerasi E & Melloul D 1999 Impaired β-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose. Diabetes 48 1230-1236.
-
(1999)
Diabetes
, vol.48
, pp. 1230-1236
-
-
Marshak, S.1
Leibowitz, G.2
Bertuzzi, F.3
Socci, C.4
Kaiser, N.5
Gross, D.J.6
Cerasi, E.7
Melloul, D.8
-
23
-
-
0030067124
-
Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
-
Matschinsky FM 1996 Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 45 223-241.
-
(1996)
Diabetes
, vol.45
, pp. 223-241
-
-
Matschinsky, F.M.1
-
24
-
-
0031020374
-
Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells
-
Matsuoka T, Kajimoto Y, Watada H, Kaneto H, Kishimoto M, Umayahara Y, Fujitani Y, Kamada T, Kawamori R & Yamasaki Y 1997 Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells. Journal of Clinical Investigation 99 144-150.
-
(1997)
Journal of Clinical Investigation
, vol.99
, pp. 144-150
-
-
Matsuoka, T.1
Kajimoto, Y.2
Watada, H.3
Kaneto, H.4
Kishimoto, M.5
Umayahara, Y.6
Fujitani, Y.7
Kamada, T.8
Kawamori, R.9
Yamasaki, Y.10
-
25
-
-
0021723668
-
The dynamic insulin secretory response of isolated pancreatic islets of the diabetic mouse. Evidence for a gene dosage effect on insulin secretion
-
Molina JM, Premdas FH, Klenck RE, Eddlestone G, Oldham SB & Lipson LG 1984 The dynamic insulin secretory response of isolated pancreatic islets of the diabetic mouse. Evidence for a gene dosage effect on insulin secretion. Diabetes 33 1120-1123.
-
(1984)
Diabetes
, vol.33
, pp. 1120-1123
-
-
Molina, J.M.1
Premdas, F.H.2
Klenck, R.E.3
Eddlestone, G.4
Oldham, S.B.5
Lipson, L.G.6
-
26
-
-
0030762209
-
Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15
-
Moran A, Zhang HJ, Olson K, Harmon JS, Poitout V & Robertson RP 1997 Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15. Journal of Clinical Investigation 99 534-539.
-
(1997)
Journal of Clinical Investigation
, vol.99
, pp. 534-539
-
-
Moran, A.1
Zhang, H.J.2
Olson, K.3
Harmon, J.S.4
Poitout, V.5
Robertson, R.P.6
-
27
-
-
0029240503
-
Genomic analysis of the C57BL/Ks mouse strain
-
Naggert JK, Mu JL, Frankel W, Bailey DW & Paigen B 1995 Genomic analysis of the C57BL/Ks mouse strain. Mammalian Genome 6 131-133.
-
(1995)
Mammalian Genome
, vol.6
, pp. 131-133
-
-
Naggert, J.K.1
Mu, J.L.2
Frankel, W.3
Bailey, D.W.4
Paigen, B.5
-
28
-
-
0028094879
-
Aberrant function and long-term survival of mouse β cells exposed in vitro to high glucose concentrations
-
Pehuet-Figoni M, Ballot E, Bach JF & Chatenoud L 1994 Aberrant function and long-term survival of mouse β cells exposed in vitro to high glucose concentrations. Cell Transplant 3 445-451.
-
(1994)
Cell Transplant.
, vol.3
, pp. 445-451
-
-
Pehuet-Figoni, M.1
Ballot, E.2
Bach, J.F.3
Chatenoud, L.4
-
29
-
-
0031700779
-
Potential benefit of inhibitors of advanced glycation end products in the progression of type II diabetes: A study with aminoguanidine in C57/BLKsJ diabetic mice
-
Piercy V, Toseland CD & Turner NC 1998 Potential benefit of inhibitors of advanced glycation end products in the progression of type II diabetes: a study with aminoguanidine in C57/BLKsJ diabetic mice. Metabolism 47 1477-1480.
-
(1998)
Metabolism
, vol.47
, pp. 1477-1480
-
-
Piercy, V.1
Toseland, C.D.2
Turner, N.C.3
-
30
-
-
0029664752
-
Chronic exposure of βTC-6 cells to supraphysiological concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator
-
Poitout V, Olson LK & Robertson RP 1996 Chronic exposure of βTC-6 cells to supraphysiological concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator. Journal of Clinical Investigation 97 1041-1046.
-
(1996)
Journal of Clinical Investigation
, vol.97
, pp. 1041-1046
-
-
Poitout, V.1
Olson, L.K.2
Robertson, R.P.3
-
31
-
-
0026110135
-
β-cells in type II diabetes mellitus
-
Porte D Jr 1991 β-cells in type II diabetes mellitus. Diabetes 40 166-180.
-
(1991)
Diabetes
, vol.40
, pp. 166-180
-
-
Porte Jr., D.1
-
32
-
-
0024451490
-
Effects of high glucose on insulin secretion by isolated rat islets and purified beta-cells and possible role of glycosylation
-
Purrello F, Vetri M, Gatta C, Gullo D & Vigneri R 1989 Effects of high glucose on insulin secretion by isolated rat islets and purified beta-cells and possible role of glycosylation. Diabetes 38 1417-1422.
-
(1989)
Diabetes
, vol.38
, pp. 1417-1422
-
-
Purrello, F.1
Vetri, M.2
Gatta, C.3
Gullo, D.4
Vigneri, R.5
-
33
-
-
0026757632
-
Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations
-
Robertson RP, Zhang HJ, Pyzdrowski KL & Walseth TF 1992 Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations. Journal of Clinical Investigation 90 320-325.
-
(1992)
Journal of Clinical Investigation
, vol.90
, pp. 320-325
-
-
Robertson, R.P.1
Zhang, H.J.2
Pyzdrowski, K.L.3
Walseth, T.F.4
-
34
-
-
0025677462
-
Coupling of β-cell desentization by hyperglycemia to excessive stimulation and circulating insulin in glucose-infused rats
-
Sako Y & Grill VE 1990 Coupling of β-cell desentization by hyperglycemia to excessive stimulation and circulating insulin in glucose-infused rats. Diabetes 39 1580-1583.
-
(1990)
Diabetes
, vol.39
, pp. 1580-1583
-
-
Sako, Y.1
Grill, V.E.2
-
35
-
-
0035157768
-
Glucose sensing in pancreatic beta-cells: A model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus
-
Schuit FC, Huypens P, Heimberg H & Pipeleers DG 2001 Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus. Diabetes 50 1-11.
-
(2001)
Diabetes
, vol.50
, pp. 1-11
-
-
Schuit, F.C.1
Huypens, P.2
Heimberg, H.3
Pipeleers, D.G.4
-
36
-
-
0026473236
-
Cellular and molecular biology of the beta cell
-
Steiner DF & James DE 1992 Cellular and molecular biology of the beta cell. Diabetologia 35 (Suppl 2) S41-S48.
-
(1992)
Diabetologia
, vol.35
, Issue.SUPPL. 2
-
-
Steiner, D.F.1
James, D.E.2
-
37
-
-
0031025828
-
Long term effects of aminoguanidine on insulin release and biosynthesis: Evidence that the formation of advanced glycation end products inhibits B cell function
-
Tajiri Y, Moller C & Grill V 1997 Long term effects of aminoguanidine on insulin release and biosynthesis: Evidence that the formation of advanced glycation end products inhibits B cell function. Endocrinology 138 273-280.
-
(1997)
Endocrinology
, vol.138
, pp. 273-280
-
-
Tajiri, Y.1
Moller, C.2
Grill, V.3
-
38
-
-
0029417331
-
Pancreatic β-cell-specific targeted disruption of glucokinase gene
-
Terauchi Y, Sakura H, Yasuda K, Iwamoto K, Takahashi N, Ito K, Kasai H, Suzuki H, Ueda O, Kamada N, Jishage K, Komeda K, Noda M, Kanazawa Y, Tanigushi S, Miwa I, Akanuma Y, Kodama T, Yazaki Y & Kadowaki T 1995 Pancreatic β-cell-specific targeted disruption of glucokinase gene. Journal of Biological Chemistry 270 30253-30256.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 30253-30256
-
-
Terauchi, Y.1
Sakura, H.2
Yasuda, K.3
Iwamoto, K.4
Takahashi, N.5
Ito, K.6
Kasai, H.7
Suzuki, H.8
Ueda, O.9
Kamada, N.10
Jishage, K.11
Komeda, K.12
Noda, M.13
Kanazawa, Y.14
Tanigushi, S.15
Miwa, I.16
Akanuma, Y.17
Kodama, T.18
Yazaki, Y.19
Kadowaki, T.20
more..
-
39
-
-
0037341501
-
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy
-
Tikellis C, Johnston CI, Forbes JM, Burns WC, Burrell LM, Risvanis J & Cooper ME 2003 Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy. Hypertension 41 392-397.
-
(2003)
Hypertension
, vol.41
, pp. 392-397
-
-
Tikellis, C.1
Johnston, C.I.2
Forbes, J.M.3
Burns, W.C.4
Burrell, L.M.5
Risvanis, J.6
Cooper, M.E.7
-
40
-
-
1842475446
-
Improved islet morphology following blockade of the renin angiotensin system in the Zucker diabetic fatty rat
-
Tikellis C, Wookey PJ, Candido R, Andrikopoulos S, Thomas MC & Cooper ME 2004 Improved islet morphology following blockade of the renin angiotensin system in the Zucker diabetic fatty rat. Diabetes 53 989-997.
-
(2004)
Diabetes
, vol.53
, pp. 989-997
-
-
Tikellis, C.1
Wookey, P.J.2
Candido, R.3
Andrikopoulos, S.4
Thomas, M.C.5
Cooper, M.E.6
|