-
1
-
-
34547228831
-
Atypical mitogen-activated protein kinases: Structure, regulation and functions
-
Coulombe P, Meloche S. Atypical mitogen-activated protein kinases: structure, regulation and functions. Biochim Biophys Acta 2007; 1773: 1376-87.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1376-1387
-
-
Coulombe, P.1
Meloche, S.2
-
2
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene 2007; 26: 3100-12.
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
3
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
Roux PP, Blenis J. ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 2004; 68: 320-44.
-
(2004)
Microbiol Mol Biol Rev
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
4
-
-
33244471768
-
MAPKAP kinases - MKs - two's company, three's a crowd
-
Gaestel M. MAPKAP kinases - MKs - two's company, three's a crowd. Nat Rev Mol Cell Biol 2006; 7: 120-30.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 120-130
-
-
Gaestel, M.1
-
5
-
-
52049108016
-
Specificity of signaling from MAPKs to MAPKAPKs: Kinases' tango nuevo
-
Gaestel M. Specificity of signaling from MAPKs to MAPKAPKs: Kinases' tango nuevo. Front Biosci 2008; 13: 6050-9.
-
(2008)
Front Biosci
, vol.13
, pp. 6050-6059
-
-
Gaestel, M.1
-
6
-
-
0037400611
-
Molecular recognitions in the MAP kinase cascades
-
Tanoue T, Nishida E. Molecular recognitions in the MAP kinase cascades. Cell Signal 2003; 15: 455-62.
-
(2003)
Cell Signal
, vol.15
, pp. 455-462
-
-
Tanoue, T.1
Nishida, E.2
-
7
-
-
0037392942
-
The specificities of protein kinase inhibitors: An update
-
Bain J, McLauchlan H, Elliott M, Cohen P. The specificities of protein kinase inhibitors: An update. Biochem J 2003; 371: 199-204.
-
(2003)
Biochem J
, vol.371
, pp. 199-204
-
-
Bain, J.1
McLauchlan, H.2
Elliott, M.3
Cohen, P.4
-
8
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, et al. The selectivity of protein kinase inhibitors: A further update. Biochem J 2007; 408: 297-315.
-
(2007)
Biochem J
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
-
9
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000; 351: 95-105.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
10
-
-
35348907987
-
Protein kinases as small molecule inhibitor targets in inflammation
-
Gaestel M, Mengel A, Bothe U, Asadullah K. Protein kinases as small molecule inhibitor targets in inflammation. Curr Med Chem 2007; 14: 2214-34.
-
(2007)
Curr Med Chem
, vol.14
, pp. 2214-2234
-
-
Gaestel, M.1
Mengel, A.2
Bothe, U.3
Asadullah, K.4
-
11
-
-
0037392942
-
The specificities of protein kinase inhibitors: An update
-
Bain J, McLauchlan H, Elliott M, Cohen P. The specificities of protein kinase inhibitors: An update. Biochem.J 2003; 371: 199-204.
-
(2003)
Biochem.J
, vol.371
, pp. 199-204
-
-
Bain, J.1
McLauchlan, H.2
Elliott, M.3
Cohen, P.4
-
12
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem.J 2000; 351: 95-105.
-
(2000)
Biochem.J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
13
-
-
0031197185
-
Protein kinase inhibition: Natural and synthetic variations on a theme
-
Taylor SS, Radzio-Andzelm E. Protein kinase inhibition: Natural and synthetic variations on a theme. Curr Opin Chem Biol 1997; 1: 219-26
-
(1997)
Curr Opin Chem Biol
, vol.1
, pp. 219-226
-
-
Taylor, S.S.1
Radzio-Andzelm, E.2
-
14
-
-
0343492260
-
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
-
Rapp UR, Goldsborough MD, Mark GE, Bonner TI, Groffen J, Reynolds FH Jr, et al. Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus. Proc Natl Acad Sci USA 1983; 80: 4218-22.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 4218-4222
-
-
Rapp, U.R.1
Goldsborough, M.D.2
Mark, G.E.3
Bonner, T.I.4
Groffen, J.5
Reynolds Jr, F.H.6
-
15
-
-
13144279271
-
Autoregulation of the Raf-1 serine/threonine kinase
-
Cutler RE, Jr., Stephens, RM, Saracino, MR, Morrison, DK. Autoregulation of the Raf-1 serine/threonine kinase. Proc Natl Acad Sci USA 1998; 95: 9214-9.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9214-9219
-
-
Cutler Jr., R.E.1
Stephens, R.M.2
Saracino, M.R.3
Morrison, D.K.4
-
16
-
-
33845731247
-
Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms
-
Hmitou I, Druillennec S, Valluet A, Peyssonnaux C, Eychene A. Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms. Mol Cell Biol 2007; 27: 31-43.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 31-43
-
-
Hmitou, I.1
Druillennec, S.2
Valluet, A.3
Peyssonnaux, C.4
Eychene, A.5
-
17
-
-
0028875318
-
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif
-
Engel K, Schultz H, Martin F, Kotlyarov A, Plath K, Hahn M, et al. Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif. J Biol Chem 1995; 270: 27213-21.
-
(1995)
J Biol Chem
, vol.270
, pp. 27213-27221
-
-
Engel, K.1
Schultz, H.2
Martin, F.3
Kotlyarov, A.4
Plath, K.5
Hahn, M.6
-
18
-
-
0028883299
-
Characterization of an autoinhibitory domain in human mitogen-activated protein kinase-activated protein kinase 2
-
Zu YL, Ai Y, Huang CK. Characterization of an autoinhibitory domain in human mitogen-activated protein kinase-activated protein kinase 2. J Biol Chem 1995; 270: 202-6.
-
(1995)
J Biol Chem
, vol.270
, pp. 202-206
-
-
Zu, Y.L.1
Ai, Y.2
Huang, C.K.3
-
19
-
-
0030739229
-
Effect of protein kinase inhibitors on activity of mammalian small heat-shock protein (HSP25) kinase
-
Hayess K, Benndorf R. Effect of protein kinase inhibitors on activity of mammalian small heat-shock protein (HSP25) kinase. Biochem Pharmacol 1997; 53: 1239-47.
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 1239-1247
-
-
Hayess, K.1
Benndorf, R.2
-
20
-
-
27644575157
-
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
-
Kolch W. Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat Rev Mol Cell Biol 2005; 6: 827-37.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 827-837
-
-
Kolch, W.1
-
22
-
-
1642441902
-
Docking interactions in the c-Jun N-terminal kinase pathway
-
Mooney LM, Whitmarsh AJ. Docking interactions in the c-Jun N-terminal kinase pathway. J Biol Chem 2004; 279: 11843-52.
-
(2004)
J Biol Chem
, vol.279
, pp. 11843-11852
-
-
Mooney, L.M.1
Whitmarsh, A.J.2
-
23
-
-
0032508714
-
A mammalian scaffold complex that selectively mediates MAP kinase activation
-
Whitmarsh AJ, Cavanagh J, Tournier C, Yasuda J, Davis RJ. A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 1998; 281: 1671-4.
-
(1998)
Science
, vol.281
, pp. 1671-1674
-
-
Whitmarsh, A.J.1
Cavanagh, J.2
Tournier, C.3
Yasuda, J.4
Davis, R.J.5
-
24
-
-
33744959530
-
Interacting JNK-docking sites in MKK7 promote binding and activation of JNK MAP kinases
-
Ho DT, Bardwell AJ, Grewal S, Iverson C, Bardwell L. Interacting JNK-docking sites in MKK7 promote binding and activation of JNK MAP kinases. J Biol Chem 2006; 281(19): 13169-79.
-
(2006)
J Biol Chem
, vol.281
, Issue.19
, pp. 13169-13179
-
-
Ho, D.T.1
Bardwell, A.J.2
Grewal, S.3
Iverson, C.4
Bardwell, L.5
-
25
-
-
20844449066
-
Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases
-
Takekawa M, Tatebayashi K, Saito H. Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases. Mol Cell 2005; 18: 295-306.
-
(2005)
Mol Cell
, vol.18
, pp. 295-306
-
-
Takekawa, M.1
Tatebayashi, K.2
Saito, H.3
-
26
-
-
0037400611
-
Molecular recognitions in the MAP kinase cascades
-
Tanoue T, Nishida E. Molecular recognitions in the MAP kinase cascades. Cell Signal 2003; 15: 455-62.
-
(2003)
Cell Signal
, vol.15
, pp. 455-462
-
-
Tanoue, T.1
Nishida, E.2
-
27
-
-
0035254671
-
Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions
-
Tanoue T, Maeda R, Adachi M, Nishida E. Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions. EMBO J 2001; 20: 466-79.
-
(2001)
EMBO J
, vol.20
, pp. 466-479
-
-
Tanoue, T.1
Maeda, R.2
Adachi, M.3
Nishida, E.4
-
28
-
-
0036289349
-
Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b
-
Chang CI, Xu BE, Akella R, Cobb MH, Goldsmith EJ. Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b. Mol.Cell 2002; 9: 1241-9.
-
(2002)
Mol.Cell
, vol.9
, pp. 1241-1249
-
-
Chang, C.I.1
Xu, B.E.2
Akella, R.3
Cobb, M.H.4
Goldsmith, E.J.5
-
29
-
-
0037188868
-
Signal transduction. MAP kinase signaling specificity
-
Weston CR, Lambright DG, Davis RJ. Signal transduction. MAP kinase signaling specificity. Science 2002; 296: 2345-7.
-
(2002)
Science
, vol.296
, pp. 2345-2347
-
-
Weston, C.R.1
Lambright, D.G.2
Davis, R.J.3
-
30
-
-
0033545604
-
A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1
-
Gavin AC, Nebreda AR. A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1. Curr Biol 1999; 9: 281-4.
-
(1999)
Curr Biol
, vol.9
, pp. 281-284
-
-
Gavin, A.C.1
Nebreda, A.R.2
-
31
-
-
0030606319
-
c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions
-
Kallunki T, Deng T, Hibi M, Karin M. c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell 1996; 87: 929-39.
-
(1996)
Cell
, vol.87
, pp. 929-939
-
-
Kallunki, T.1
Deng, T.2
Hibi, M.3
Karin, M.4
-
32
-
-
0029885419
-
Selective interaction of JNK protein kinase isoforms with transcription factors
-
Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Derijard B, Davis RJ. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 1996; 15: 2760-70.
-
(1996)
EMBO J
, vol.15
, pp. 2760-2770
-
-
Gupta, S.1
Barrett, T.2
Whitmarsh, A.J.3
Cavanagh, J.4
Sluss, H.K.5
Derijard, B.6
Davis, R.J.7
-
33
-
-
0034284131
-
Docking domains and substrate-specificity determination for MAP kinases
-
Sharrocks AD, Yang SH, Galanis A. Docking domains and substrate-specificity determination for MAP kinases. Trends Biochem Sci 2000; 25: 448-53.
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 448-453
-
-
Sharrocks, A.D.1
Yang, S.H.2
Galanis, A.3
-
34
-
-
0036223297
-
Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor
-
Dunn C, Wiltshire C, MacLaren A, Gillespie DA. Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor. Cell Signal 2002; 14: 585-93.
-
(2002)
Cell Signal
, vol.14
, pp. 585-593
-
-
Dunn, C.1
Wiltshire, C.2
MacLaren, A.3
Gillespie, D.A.4
-
35
-
-
0032509335
-
Analysis of the interaction between c-Jun and c-Jun N-terminal kinase in vivo
-
May GH, Allen KE, Clark W, Funk M, Gillespie DA. Analysis of the interaction between c-Jun and c-Jun N-terminal kinase in vivo. J Biol Chem 1998; 273: 33429-35.
-
(1998)
J Biol Chem
, vol.273
, pp. 33429-33435
-
-
May, G.H.1
Allen, K.E.2
Clark, W.3
Funk, M.4
Gillespie, D.A.5
-
36
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, et al. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 1994; 76: 1025-37.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.H.3
Barrett, T.4
Su, B.5
Deng, T.6
-
37
-
-
0027423418
-
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
-
Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 1993; 7: 2135-48.
-
(1993)
Genes Dev
, vol.7
, pp. 2135-2148
-
-
Hibi, M.1
Lin, A.2
Smeal, T.3
Minden, A.4
Karin, M.5
-
38
-
-
0030972494
-
Interaction of MAP kinase with MAP kinase kinase: Its possible role in the control of nucleocytoplasmic transport of MAP kinase
-
Fukuda M, Gotoh Y, Nishida E. Interaction of MAP kinase with MAP kinase kinase: Its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J 1997; 16: 1901-8.
-
(1997)
EMBO J
, vol.16
, pp. 1901-1908
-
-
Fukuda, M.1
Gotoh, Y.2
Nishida, E.3
-
39
-
-
0032536816
-
Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1
-
Yang SH, Whitmarsh AJ, Davis RJ, Sharrocks AD. Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO J 1998; 17: 1740-9.
-
(1998)
EMBO J
, vol.17
, pp. 1740-1749
-
-
Yang, S.H.1
Whitmarsh, A.J.2
Davis, R.J.3
Sharrocks, A.D.4
-
40
-
-
0035847076
-
Selective targeting of MAPKs to the ETS domain transcription factor SAP-1
-
Galanis A, Yang SH, Sharrocks AD. Selective targeting of MAPKs to the ETS domain transcription factor SAP-1. J Biol Chem 2001; 276: 965-73.
-
(2001)
J Biol Chem
, vol.276
, pp. 965-973
-
-
Galanis, A.1
Yang, S.H.2
Sharrocks, A.D.3
-
41
-
-
0034644656
-
Creation of a stress-activated p90 ribosomal S6 kinase. The carboxyl-terminal tail of the MAPK-activated protein kinases dictates the signal transduction pathway in which they function
-
Smith JA, Poteet-Smith CE, Lannigan DA, Freed TA, Zoltoski AJ, Sturgill TW. Creation of a stress-activated p90 ribosomal S6 kinase. The carboxyl-terminal tail of the MAPK-activated protein kinases dictates the signal transduction pathway in which they function. J Biol Chem 2000; 275: 31588-93.
-
(2000)
J Biol Chem
, vol.275
, pp. 31588-31593
-
-
Smith, J.A.1
Poteet-Smith, C.E.2
Lannigan, D.A.3
Freed, T.A.4
Zoltoski, A.J.5
Sturgill, T.W.6
-
42
-
-
0033788484
-
A conserved docking motif in MAP kinases common to substrates, activators and regulators
-
Tanoue T, Adachi M, Moriguchi T, Nishida E. A conserved docking motif in MAP kinases common to substrates, activators and regulators. Nat Cell Biol 2000; 2: 110-6.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 110-116
-
-
Tanoue, T.1
Adachi, M.2
Moriguchi, T.3
Nishida, E.4
-
43
-
-
0035254671
-
Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions
-
Tanoue T, Maeda R, Adachi M, Nishida E. Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions. EMBO J 2001; 20: 466-79.
-
(2001)
EMBO J
, vol.20
, pp. 466-479
-
-
Tanoue, T.1
Maeda, R.2
Adachi, M.3
Nishida, E.4
-
44
-
-
0033011595
-
Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors
-
Yang SH, Galanis A, Sharrocks AD. Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors. Mol Cell Biol 1999; 19: 4028-38.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4028-4038
-
-
Yang, S.H.1
Galanis, A.2
Sharrocks, A.D.3
-
45
-
-
4344695112
-
ERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motif
-
Barsyte-Lovejoy D, Galanis A, Clancy A, Sharrocks AD. ERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motif. Biochem J 2004; 381: 693-9.
-
(2004)
Biochem J
, vol.381
, pp. 693-699
-
-
Barsyte-Lovejoy, D.1
Galanis, A.2
Clancy, A.3
Sharrocks, A.D.4
-
46
-
-
0035854673
-
A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs
-
Tanoue T, Yamamoto T, Maeda R, Nishida E. A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs. J Biol Chem 2001; 276: 26629-39.
-
(2001)
J Biol Chem
, vol.276
, pp. 26629-26639
-
-
Tanoue, T.1
Yamamoto, T.2
Maeda, R.3
Nishida, E.4
-
47
-
-
0033555229
-
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase
-
Jacobs D, Glossip D, Xing H, Muslin AJ, Kornfeld K. Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase. Genes Dev 1999; 13: 163-75.
-
(1999)
Genes Dev
, vol.13
, pp. 163-175
-
-
Jacobs, D.1
Glossip, D.2
Xing, H.3
Muslin, A.J.4
Kornfeld, K.5
-
48
-
-
22744449792
-
Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo
-
Dimitri CA, Dowdle W, MacKeigan JP, Blenis J, Murphy LO. Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo. Curr Biol 2005; 15: 1319-24.
-
(2005)
Curr Biol
, vol.15
, pp. 1319-1324
-
-
Dimitri, C.A.1
Dowdle, W.2
MacKeigan, J.P.3
Blenis, J.4
Murphy, L.O.5
-
49
-
-
33947312823
-
Interfering with MAP kinase docking interactions: Implications and perspective for the p38 route
-
Mayor F, Jr., Jurado-Pueyo M, Campos PM, Murga C. Interfering with MAP kinase docking interactions: Implications and perspective for the p38 route. Cell Cycle 2007; 6: 528-33.
-
(2007)
Cell Cycle
, vol.6
, pp. 528-533
-
-
Mayor Jr., F.1
Jurado-Pueyo, M.2
Campos, P.M.3
Murga, C.4
-
50
-
-
0034595707
-
ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions
-
MacKenzie SJ, Baillie GS, McPhee I, Bolger GB, Houslay MD. ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions. J Biol Chem 2000; 275: 16609-17.
-
(2000)
J Biol Chem
, vol.275
, pp. 16609-16617
-
-
MacKenzie, S.J.1
Baillie, G.S.2
McPhee, I.3
Bolger, G.B.4
Houslay, M.D.5
-
51
-
-
0032534791
-
PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif
-
Pulido R, Zuniga A, Ullrich A. PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif. EMBO J 1998; 17: 7337-50.
-
(1998)
EMBO J
, vol.17
, pp. 7337-7350
-
-
Pulido, R.1
Zuniga, A.2
Ullrich, A.3
-
52
-
-
33751261134
-
Mechanisms of MAPK signalling specificity
-
Bardwell L. Mechanisms of MAPK signalling specificity. Biochem Soc Trans 2006; 34: 837-41.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 837-841
-
-
Bardwell, L.1
-
53
-
-
4344576752
-
The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK
-
Barr RK, Boehm I, Attwood PV, Watt PM, Bogoyevitch MA. The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK. J Biol Chem 2004; 279: 36327-38.
-
(2004)
J Biol Chem
, vol.279
, pp. 36327-36338
-
-
Barr, R.K.1
Boehm, I.2
Attwood, P.V.3
Watt, P.M.4
Bogoyevitch, M.A.5
-
54
-
-
36749011295
-
Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase
-
Zhu Y, Li H, Long C, Hu L, Xu H, Liu L, et al. Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase. Mol Cell 2007; 28: 899-913.
-
(2007)
Mol Cell
, vol.28
, pp. 899-913
-
-
Zhu, Y.1
Li, H.2
Long, C.3
Hu, L.4
Xu, H.5
Liu, L.6
-
55
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 1999; 285: 1569-72.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
56
-
-
0031759170
-
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
-
Nagahara H, Vocero-Akbani AM, Snyder EL, Ho A, Latham DG, Lissy NA, et al. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat Med 1998; 4: 1449-52.
-
(1998)
Nat Med
, vol.4
, pp. 1449-1452
-
-
Nagahara, H.1
Vocero-Akbani, A.M.2
Snyder, E.L.3
Ho, A.4
Latham, D.G.5
Lissy, N.A.6
-
58
-
-
1542609485
-
Transduction peptides: From technology to physiology
-
Joliot A, Prochiantz A. Transduction peptides: From technology to physiology. Nat Cell Biol 2004; 6: 189-96.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 189-196
-
-
Joliot, A.1
Prochiantz, A.2
-
59
-
-
0035204427
-
A peptide carrier for the delivery of biologically active proteins into mammalian cells
-
Morris MC, Depollier J, Mery J, Heitz F, Divita G. A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat Biotechnol 2001; 19: 1173-6.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 1173-1176
-
-
Morris, M.C.1
Depollier, J.2
Mery, J.3
Heitz, F.4
Divita, G.5
-
60
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004; 10: 310-5.
-
(2004)
Nat Med
, vol.10
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
61
-
-
34548498615
-
Cell-permeable peptides induce dose- and length-dependent cytotoxic effects
-
Cardozo AK, Buchillier V, Mathieu M, Chen J, Ortis F, Ladriere L, et al. Cell-permeable peptides induce dose- and length-dependent cytotoxic effects. Biochim Biophys Acta 2007; 1768: 2222-34.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 2222-2234
-
-
Cardozo, A.K.1
Buchillier, V.2
Mathieu, M.3
Chen, J.4
Ortis, F.5
Ladriere, L.6
-
62
-
-
0344393408
-
Regulation of MAP kinase signaling modules by scaffold proteins in mammals
-
Morrison DK, Davis RJ. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu Rev Cell Dev Biol 2003; 19: 91-118
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 91-118
-
-
Morrison, D.K.1
Davis, R.J.2
-
63
-
-
0030826412
-
A cytoplasmic inhibitor of the JNK signal transduction pathway
-
Dickens M, Rogers JS, Cavanagh J, Raitano A, Xia Z, Halpern JR, et al. A cytoplasmic inhibitor of the JNK signal transduction pathway. Science 1997; 277: 693-6.
-
(1997)
Science
, vol.277
, pp. 693-696
-
-
Dickens, M.1
Rogers, J.S.2
Cavanagh, J.3
Raitano, A.4
Xia, Z.5
Halpern, J.R.6
-
64
-
-
0032825497
-
The JIP group of mitogen-activated protein kinase scaffold proteins
-
Yasuda J, Whitmarsh AJ, Cavanagh J, Sharma M, Davis RJ. The JIP group of mitogen-activated protein kinase scaffold proteins. Mol Cell Biol 1999; 19: 7245-54.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7245-7254
-
-
Yasuda, J.1
Whitmarsh, A.J.2
Cavanagh, J.3
Sharma, M.4
Davis, R.J.5
-
65
-
-
25444516196
-
JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity
-
Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, et al. JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity. Mol Cell Biol 2005; 25: 8619-30.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8619-8630
-
-
Kadoya, T.1
Khurana, A.2
Tcherpakov, M.3
Bromberg, K.D.4
Didier, C.5
Broday, L.6
-
66
-
-
0030614745
-
Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells
-
Marti A, Luo Z, Cunningham C, Ohta Y, Hartwig J, Stossel TP, et al. Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells. J Biol Chem 1997; 272: 2620-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 2620-2628
-
-
Marti, A.1
Luo, Z.2
Cunningham, C.3
Ohta, Y.4
Hartwig, J.5
Stossel, T.P.6
-
67
-
-
0035796480
-
A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation
-
Girardin SE, Yaniv M. A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation. EMBO J 2001; 20: 3437-46.
-
(2001)
EMBO J
, vol.20
, pp. 3437-3446
-
-
Girardin, S.E.1
Yaniv, M.2
-
68
-
-
2242420013
-
Binding of JNK/SAPK to MEKK1 is regulated by phosphorylation
-
Gallagher ED, Xu S, Moomaw C, Slaughter CA, Cobb MH. Binding of JNK/SAPK to MEKK1 is regulated by phosphorylation. J Biol Chem 2002; 277: 45785-92.
-
(2002)
J Biol Chem
, vol.277
, pp. 45785-45792
-
-
Gallagher, E.D.1
Xu, S.2
Moomaw, C.3
Slaughter, C.A.4
Cobb, M.H.5
-
69
-
-
0031450154
-
MEKK1 binds directly to the c-Jun N-terminal kinases/ stress-activated protein kinases
-
Xu S, Cobb MH. MEKK1 binds directly to the c-Jun N-terminal kinases/ stress-activated protein kinases. J Biol Chem 1997; 272: 32056-60.
-
(1997)
J Biol Chem
, vol.272
, pp. 32056-32060
-
-
Xu, S.1
Cobb, M.H.2
-
70
-
-
0037439170
-
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis
-
Xu Z, Kukekov NV, Greene LA. POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. EMBO J 2003; 22: 252-61.
-
(2003)
EMBO J
, vol.22
, pp. 252-261
-
-
Xu, Z.1
Kukekov, N.V.2
Greene, L.A.3
-
71
-
-
0032473569
-
A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways
-
Tapon N, Nagata K, Lamarche N, Hall A. A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways. EMBO J 1998; 17: 1395-404.
-
(1998)
EMBO J
, vol.17
, pp. 1395-1404
-
-
Tapon, N.1
Nagata, K.2
Lamarche, N.3
Hall, A.4
-
72
-
-
33744950092
-
Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs
-
Kukekov NV, Xu Z, Greene LA. Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. J Biol Chem 2006; 281: 15517-24.
-
(2006)
J Biol Chem
, vol.281
, pp. 15517-15524
-
-
Kukekov, N.V.1
Xu, Z.2
Greene, L.A.3
-
73
-
-
27844475685
-
The RING-finger scaffold protein plenty of SH3s targets TAK1 to control immunity signalling in Drosophila
-
Tsuda M, Langmann C, Harden N, Aigaki T. The RING-finger scaffold protein plenty of SH3s targets TAK1 to control immunity signalling in Drosophila. EMBO Rep 2005; 6: 1082-7.
-
(2005)
EMBO Rep
, vol.6
, pp. 1082-1087
-
-
Tsuda, M.1
Langmann, C.2
Harden, N.3
Aigaki, T.4
-
74
-
-
0031915453
-
IB1, a JIP-1-related nuclear protein present in insulin-secreting cells
-
Bonny C, Nicod P, Waeber G. IB1, a JIP-1-related nuclear protein present in insulin-secreting cells. J Biol Chem 1998; 273: 1843-6.
-
(1998)
J Biol Chem
, vol.273
, pp. 1843-1846
-
-
Bonny, C.1
Nicod, P.2
Waeber, G.3
-
75
-
-
0034104298
-
The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes
-
Waeber G, Delplanque J, Bonny C, Mooser V, Steinmann M, Widmann C, et al. The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes. Nat Genet 2000; 24: 291-5.
-
(2000)
Nat Genet
, vol.24
, pp. 291-295
-
-
Waeber, G.1
Delplanque, J.2
Bonny, C.3
Mooser, V.4
Steinmann, M.5
Widmann, C.6
-
76
-
-
0032422785
-
Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals
-
Whitmarsh AJ, Davis RJ. Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals. Trends Biochem Sci 1998; 23: 481-5.
-
(1998)
Trends Biochem Sci
, vol.23
, pp. 481-485
-
-
Whitmarsh, A.J.1
Davis, R.J.2
-
77
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death
-
Bonny C, Oberson A, Negri S, Sauser C, Schorderet DF. Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death. Diabetes 2001; 50: 77-82.
-
(2001)
Diabetes
, vol.50
, pp. 77-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
Schorderet, D.F.5
-
78
-
-
0037192843
-
Identification of the critical features of a small peptide inhibitor of JNK activity
-
Barr RK, Kendrick TS, Bogoyevitch MA. Identification of the critical features of a small peptide inhibitor of JNK activity. J Biol Chem 2002; 277: 10987-97.
-
(2002)
J Biol Chem
, vol.277
, pp. 10987-10997
-
-
Barr, R.K.1
Kendrick, T.S.2
Bogoyevitch, M.A.3
-
79
-
-
3042689209
-
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
-
Heo YS, Kim SK, Seo CI, Kim YK, Sung BJ, Lee HS, et al. Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125. EMBO J 2004; 23: 2185-95.
-
(2004)
EMBO J
, vol.23
, pp. 2185-2195
-
-
Heo, Y.S.1
Kim, S.K.2
Seo, C.I.3
Kim, Y.K.4
Sung, B.J.5
Lee, H.S.6
-
80
-
-
5644223099
-
Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1
-
Barr RK, Hopkins RM, Watt PM, Bogoyevitch MA. Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1. J Biol Chem 2004; 279: 43178-89.
-
(2004)
J Biol Chem
, vol.279
, pp. 43178-43189
-
-
Barr, R.K.1
Hopkins, R.M.2
Watt, P.M.3
Bogoyevitch, M.A.4
-
81
-
-
0042858567
-
A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates
-
Ho DT, Bardwell AJ, Abdollahi M, Bardwell L. A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates. J Biol Chem 2003; 278: 32662-72.
-
(2003)
J Biol Chem
, vol.278
, pp. 32662-32672
-
-
Ho, D.T.1
Bardwell, A.J.2
Abdollahi, M.3
Bardwell, L.4
-
82
-
-
0141924878
-
Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes
-
Holzberg D, Knight CG, Dittrich-Breiholz O, Schneider H, Dorrie A, Hoffmann E, et al. Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes. J Biol Chem 2003; 278: 40213-23.
-
(2003)
J Biol Chem
, vol.278
, pp. 40213-40223
-
-
Holzberg, D.1
Knight, C.G.2
Dittrich-Breiholz, O.3
Schneider, H.4
Dorrie, A.5
Hoffmann, E.6
-
83
-
-
0141724805
-
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
-
Borsello T, Clarke PG, Hirt L, Vercelli A, Repici M, Schorderet DF, et al. A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia. Nat Med 2003; 9: 1180-6
-
(2003)
Nat Med
, vol.9
, pp. 1180-1186
-
-
Borsello, T.1
Clarke, P.G.2
Hirt, L.3
Vercelli, A.4
Repici, M.5
Schorderet, D.F.6
-
84
-
-
40949113125
-
-
Esneault E, Castagne V, Moser P, Bonny C, Bernaudin M. D-JNKi, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats. Neuroscience 2008; 152: 308-20.
-
Esneault E, Castagne V, Moser P, Bonny C, Bernaudin M. D-JNKi, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats. Neuroscience 2008; 152: 308-20.
-
-
-
-
85
-
-
33846202874
-
Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons
-
Centeno C, Repici M, Chatton JY, Riederer BM, Bonny C, Nicod P, et al. Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons. Cell Death Differ 2007; 14: 240-53.
-
(2007)
Cell Death Differ
, vol.14
, pp. 240-253
-
-
Centeno, C.1
Repici, M.2
Chatton, J.Y.3
Riederer, B.M.4
Bonny, C.5
Nicod, P.6
-
86
-
-
36649004091
-
Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation
-
Repici M, Centeno C, Tomasi S, Forloni G, Bonny C, Vercelli A, et al. Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation. Neuroscience 2007; 150: 40-9.
-
(2007)
Neuroscience
, vol.150
, pp. 40-49
-
-
Repici, M.1
Centeno, C.2
Tomasi, S.3
Forloni, G.4
Bonny, C.5
Vercelli, A.6
-
87
-
-
33645460235
-
A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: Respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance
-
Zhuang ZY, Wen YR, Zhang DR, Borsello T, Bonny C, Strichartz GR, et al. A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: Respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance. J Neurosci 2006; 26: 3551-60.
-
(2006)
J Neurosci
, vol.26
, pp. 3551-3560
-
-
Zhuang, Z.Y.1
Wen, Y.R.2
Zhang, D.R.3
Borsello, T.4
Bonny, C.5
Strichartz, G.R.6
-
88
-
-
0141593385
-
Repression of phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice
-
Im JY, Lee KW, Kim MH, Lee SH, Ha HY, Cho IH, et al. Repression of phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice. J Neurosci Res 2003; 74: 326-32.
-
(2003)
J Neurosci Res
, vol.74
, pp. 326-332
-
-
Im, J.Y.1
Lee, K.W.2
Kim, M.H.3
Lee, S.H.4
Ha, H.Y.5
Cho, I.H.6
-
89
-
-
4043073652
-
An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue
-
Jaeschke A, Czech MP, Davis RJ. An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue. Genes Dev 2004; 18: 1976-80.
-
(2004)
Genes Dev
, vol.18
, pp. 1976-1980
-
-
Jaeschke, A.1
Czech, M.P.2
Davis, R.J.3
-
90
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang DD, Kuan CY, Whitmarsh AJ, Rincon M, Zheng TS, Davis RJ, et al. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 1997; 389: 865-70.
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincon, M.4
Zheng, T.S.5
Davis, R.J.6
-
91
-
-
34548857943
-
Requirement of JIP scaffold proteins for NMDA-mediated signal transduction
-
Kennedy NJ, Martin G, Ehrhardt AG, Cavanagh-Kyros J, Kuan CY, Rakic P, et al. Requirement of JIP scaffold proteins for NMDA-mediated signal transduction. Genes Dev 2007; 21: 2336-46.
-
(2007)
Genes Dev
, vol.21
, pp. 2336-2346
-
-
Kennedy, N.J.1
Martin, G.2
Ehrhardt, A.G.3
Cavanagh-Kyros, J.4
Kuan, C.Y.5
Rakic, P.6
-
92
-
-
0035883958
-
Requirement of the JIP1 scaffold protein for stress-induced JNK activation
-
Whitmarsh AJ, Kuan CY, Kennedy NJ, Kelkar N, Haydar TF, Mordes JP, et al. Requirement of the JIP1 scaffold protein for stress-induced JNK activation. Genes Dev 2001; 15: 2421-32.
-
(2001)
Genes Dev
, vol.15
, pp. 2421-2432
-
-
Whitmarsh, A.J.1
Kuan, C.Y.2
Kennedy, N.J.3
Kelkar, N.4
Haydar, T.F.5
Mordes, J.P.6
-
93
-
-
21044453408
-
Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes
-
Jaeschke A, Rincon M, Doran B, Reilly J, Neuberg D, Greiner DL, et al. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad Sci USA 2005; 102: 6931-5.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6931-6935
-
-
Jaeschke, A.1
Rincon, M.2
Doran, B.3
Reilly, J.4
Neuberg, D.5
Greiner, D.L.6
-
94
-
-
0034596017
-
IB1 reduces cytokine-induced apoptosis of insulin-secreting cells
-
Bonny C, Oberson A, Steinmann M, Schorderet DF, Nicod P, Waeber G. IB1 reduces cytokine-induced apoptosis of insulin-secreting cells. J Biol Chem 2000; 275: 16466-72.
-
(2000)
J Biol Chem
, vol.275
, pp. 16466-16472
-
-
Bonny, C.1
Oberson, A.2
Steinmann, M.3
Schorderet, D.F.4
Nicod, P.5
Waeber, G.6
-
95
-
-
7044230885
-
Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide
-
Kaneto H, Nakatani Y, Miyatsuka T, Kawamori D, Matsuoka TA, Matsuhisa M, et al. Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide. Nat Med 2004; 10: 1128-32.
-
(2004)
Nat Med
, vol.10
, pp. 1128-1132
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
Kawamori, D.4
Matsuoka, T.A.5
Matsuhisa, M.6
-
96
-
-
0033994234
-
Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
-
Pirvola U, Xing-Qun L, Virkkala J, Saarma M, Murakata C, Camoratto AM, et al. Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation. J Neurosci 2000; 20: 43-50.
-
(2000)
J Neurosci
, vol.20
, pp. 43-50
-
-
Pirvola, U.1
Xing-Qun, L.2
Virkkala, J.3
Saarma, M.4
Murakata, C.5
Camoratto, A.M.6
-
97
-
-
33745278912
-
D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma
-
Eshraghi AA, He J, Mou CH, Polak M, Zine A, Bonny C, et al. D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma. Otol Neurotol 2006; 27: 504-11.
-
(2006)
Otol Neurotol
, vol.27
, pp. 504-511
-
-
Eshraghi, A.A.1
He, J.2
Mou, C.H.3
Polak, M.4
Zine, A.5
Bonny, C.6
-
98
-
-
33947316135
-
Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity
-
Eshraghi AA, Wang J, Adil E, He J, Zine A, Bublik M, et al. Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity. Hear Res 2007; 226: 168-77.
-
(2007)
Hear Res
, vol.226
, pp. 168-177
-
-
Eshraghi, A.A.1
Wang, J.2
Adil, E.3
He, J.4
Zine, A.5
Bublik, M.6
-
99
-
-
33847123006
-
Inhibition of the c-Jun N-terminal kinase-mediated mitochondrial cell death pathway restores auditory function in sound-exposed animals
-
Wang J, Ruel J, Ladrech S, Bonny C, van de Water TR, Puel JL. Inhibition of the c-Jun N-terminal kinase-mediated mitochondrial cell death pathway restores auditory function in sound-exposed animals. Mol Pharmacol 2007; 71: 654-66.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 654-666
-
-
Wang, J.1
Ruel, J.2
Ladrech, S.3
Bonny, C.4
van de Water, T.R.5
Puel, J.L.6
-
100
-
-
0141457877
-
A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss
-
Wang J, Van De Water TR, Bonny C, de Ribaupierre F, Puel JL, Zine A. A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss. J Neurosci 2003; 23: 8596-607.
-
(2003)
J Neurosci
, vol.23
, pp. 8596-8607
-
-
Wang, J.1
Van De Water, T.R.2
Bonny, C.3
de Ribaupierre, F.4
Puel, J.L.5
Zine, A.6
-
101
-
-
34250873816
-
Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase
-
Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL. Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol 2007; 81: 6984-92.
-
(2007)
J Virol
, vol.81
, pp. 6984-6992
-
-
Beckham, J.D.1
Goody, R.J.2
Clarke, P.3
Bonny, C.4
Tyler, K.L.5
-
102
-
-
34147099428
-
A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo
-
Milano G, Morel S, Bonny C, Samaja M, von Segesser LK, Nicod P, Vassalli G. A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo. Am J Physiol Heart Circ Physiol 2007; 292: H1828-35.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Milano, G.1
Morel, S.2
Bonny, C.3
Samaja, M.4
von Segesser, L.K.5
Nicod, P.6
Vassalli, G.7
-
103
-
-
0037444809
-
Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity
-
Bardwell AJ, Abdollahi M, Bardwell L. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity. Biochem J 2003; 370: 1077-85.
-
(2003)
Biochem J
, vol.370
, pp. 1077-1085
-
-
Bardwell, A.J.1
Abdollahi, M.2
Bardwell, L.3
-
104
-
-
0037040959
-
Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides
-
Kelemen BR, Hsiao K, Goueli SA. Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides. J Biol Chem 2002; 277: 8741-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 8741-8748
-
-
Kelemen, B.R.1
Hsiao, K.2
Goueli, S.A.3
-
105
-
-
29644445405
-
Characterization of an ERK-binding domain in microphthalmia-associated transcription factor and differential inhibition of ERK2-mediated substrate phosphorylation
-
Molina DM, Grewal S, Bardwell L. Characterization of an ERK-binding domain in microphthalmia-associated transcription factor and differential inhibition of ERK2-mediated substrate phosphorylation. J Biol Chem 2005; 280: 42051-60.
-
(2005)
J Biol Chem
, vol.280
, pp. 42051-42060
-
-
Molina, D.M.1
Grewal, S.2
Bardwell, L.3
-
106
-
-
0036051342
-
Molecular interpretation of ERK signal duration by immediate early gene products
-
Murphy LO, Smith S, Chen RH, Fingar DC, Blenis J. Molecular interpretation of ERK signal duration by immediate early gene products. Nat Cell Biol 2002; 4: 556-64.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 556-564
-
-
Murphy, L.O.1
Smith, S.2
Chen, R.H.3
Fingar, D.C.4
Blenis, J.5
-
107
-
-
23944466208
-
Context-specific inhibition of JNKs: Overcoming the dilemma of protection and damage
-
Waetzig V, Herdegen T. Context-specific inhibition of JNKs: Overcoming the dilemma of protection and damage. Trends Pharmacol Sci 2005; 26: 455-61.
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 455-461
-
-
Waetzig, V.1
Herdegen, T.2
-
108
-
-
31344439465
-
The kinetics and tissue distribution of protein transduction in mice
-
Cai SR, Xu G, Becker-Hapak M, Ma M, Dowdy SF, McLeod HL. The kinetics and tissue distribution of protein transduction in mice. Eur J Pharm.Sci 2006; 27: 311-9.
-
(2006)
Eur J Pharm.Sci
, vol.27
, pp. 311-319
-
-
Cai, S.R.1
Xu, G.2
Becker-Hapak, M.3
Ma, M.4
Dowdy, S.F.5
McLeod, H.L.6
-
109
-
-
33750358664
-
Use of cell permeable NBD peptides for suppression of inflammation
-
Strickland I, Ghosh S. Use of cell permeable NBD peptides for suppression of inflammation. Ann Rheum Dis 2006; 65(Suppl 3): Iii75-82.
-
(2006)
Ann Rheum Dis
, vol.65
, Issue.SUPPL. 3
-
-
Strickland, I.1
Ghosh, S.2
-
110
-
-
0034284715
-
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex
-
May MJ, D'Acquisto F, Madge LA, Glockner J, Pober JS, Ghosh S. Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 2000; 289: 1550-4.
-
(2000)
Science
, vol.289
, pp. 1550-1554
-
-
May, M.J.1
D'Acquisto, F.2
Madge, L.A.3
Glockner, J.4
Pober, J.S.5
Ghosh, S.6
-
111
-
-
37349081594
-
Antagonistic control of cell fates by JNK and p38-MAPK signaling
-
Wada T, Stepniak E, Hui L, Leibbrandt A, Katada T, Nishina H, et al. Antagonistic control of cell fates by JNK and p38-MAPK signaling. Cell Death Differ 2008; 15: 89-93.
-
(2008)
Cell Death Differ
, vol.15
, pp. 89-93
-
-
Wada, T.1
Stepniak, E.2
Hui, L.3
Leibbrandt, A.4
Katada, T.5
Nishina, H.6
-
112
-
-
34249334506
-
p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway
-
Hui L, Bakiri L, Mairhorfer A, Schweifer N, Haslinger C, Kenner L, et al. p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nat Genet 2007; 39: 741-9.
-
(2007)
Nat Genet
, vol.39
, pp. 741-749
-
-
Hui, L.1
Bakiri, L.2
Mairhorfer, A.3
Schweifer, N.4
Haslinger, C.5
Kenner, L.6
-
113
-
-
33747377165
-
c-Jun/ap-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity
-
Stepniak E, Ricci R, Eferl R, Sumara G, Sumara I, Rath M, et al. c-Jun/ap-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity. Genes Dev 2006; 20: 2306-14.
-
(2006)
Genes Dev
, vol.20
, pp. 2306-2314
-
-
Stepniak, E.1
Ricci, R.2
Eferl, R.3
Sumara, G.4
Sumara, I.5
Rath, M.6
-
114
-
-
1642602694
-
Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2
-
Papa S, Zazzeroni F, Bubici C, Jayawardena S, Alvarez K, Matsuda S, et al. Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2. Nat Cell Biol 2004; 6: 146-53.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 146-153
-
-
Papa, S.1
Zazzeroni, F.2
Bubici, C.3
Jayawardena, S.4
Alvarez, K.5
Matsuda, S.6
-
115
-
-
0035889252
-
Induction of gadd45beta by NF-kappaB downregulates proapoptotic JNK signalling
-
De Smaele E, Zazzeroni F, Papa S, Nguyen DU, Jin R, Jones J, et al. Induction of gadd45beta by NF-kappaB downregulates proapoptotic JNK signalling. Nature 2001; 414: 308-13.
-
(2001)
Nature
, vol.414
, pp. 308-313
-
-
De Smaele, E.1
Zazzeroni, F.2
Papa, S.3
Nguyen, D.U.4
Jin, R.5
Jones, J.6
-
116
-
-
39149122494
-
Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: A MLK-3-MKK7-dependent mechanism
-
Muniyappa H, Das KC. Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: A MLK-3-MKK7-dependent mechanism. Cell Signal 2008; 20: 675-83.
-
(2008)
Cell Signal
, vol.20
, pp. 675-683
-
-
Muniyappa, H.1
Das, K.C.2
-
117
-
-
25444498531
-
Inhibition of inflammatory bone erosion by constitutively active STAT-6 through blockade of JNK and NF-kappaB activation
-
Hirayama T, Dai S, Abbas S, Yamanaka Y, Abu-Amer Y. Inhibition of inflammatory bone erosion by constitutively active STAT-6 through blockade of JNK and NF-kappaB activation. Arthritis Rheum 2005; 52: 2719-29.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2719-2729
-
-
Hirayama, T.1
Dai, S.2
Abbas, S.3
Yamanaka, Y.4
Abu-Amer, Y.5
-
118
-
-
3543060538
-
Catalysis and function of the p38 alpha.MK2a signaling complex
-
Lukas,SM, Kroe RR, Wildeson J, Peet GW, Frego L, Davidson W, et al. Catalysis and function of the p38 alpha.MK2a signaling complex. Biochemistry 2004; 43: 9950-60.
-
(2004)
Biochemistry
, vol.43
, pp. 9950-9960
-
-
Lukas, S.M.1
Kroe, R.R.2
Wildeson, J.3
Peet, G.W.4
Frego, L.5
Davidson, W.6
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