The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK

Journal of Biological Chemistry

Volumn 279, Issue 35, 2004, Pages 36327-36338

  Barr, Renae K ^a   Boehm, Ingrid ^a   Attwood, Paul V ^a   Watt, Paul M ^a,c   Bogoyevitch, Marie A ^a,b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c Phylogica Ltd   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; PHOSPHORUS COMPOUNDS; PROTEINS;

PEPTIDES; PHOSPHATASES;

ENZYME INHIBITION;

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ARGINYLPROLYLLYSYLARGINYLPROLYLTHREONYLTHREONYLLEUCYLASPARAGINYLLEUCYLPHENY LALANINAMIDE; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; PROLINE; PROTEIN TI JIP; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING COMPETITION; BIOCHEMISTRY; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SUBSTRATE; INHIBITION KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN MOTIF; STATISTICAL SIGNIFICANCE;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID MOTIFS; ANIMALS; BETA-GALACTOSIDASE; BINDING, COMPETITIVE; COS CELLS; DATABASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KINETICS; LEUCINE; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PEPTIDES; PLASMIDS; PROLINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TEMPERATURE; THREONINE; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA;

EID: 4344576752     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402181200     Document Type: Article

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