The kinetics and tissue distribution of protein transduction in mice

European Journal of Pharmaceutical Sciences

Volumn 27, Issue 4, 2006, Pages 311-319

  Cai, Shi Rong ^a   Xu, Guang ^a   Becker Hapak, Michelle ^a   Ma, Margaret ^a   Dowdy, Steven F ^a,b   McLeod, Howard L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Protein transduction domain; TAT fusion protein; Tissue kinetics

Indexed keywords

BETA GALACTOSIDASE; HYBRID PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG HALF LIFE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME KINETICS; ENZYME LOCALIZATION; INTESTINE; KIDNEY PARENCHYMA; LIVER; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN DOMAIN; QUANTITATIVE ANALYSIS; SPLEEN; STAINING; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ADMINISTRATION, ORAL; ANIMALS; BETA-GALACTOSIDASE; BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; GENE PRODUCTS, TAT; HALF-LIFE; HUMANS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS; TISSUE DISTRIBUTION; TRANSDUCTION, GENETIC;

EID: 31344439465     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2005.10.011     Document Type: Article

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