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Volumn 8, Issue 2, 2009, Pages 349-368

Potential role of organic sulfur compounds from Allium species in cancer prevention and therapy

Author keywords

Chemoprevention; Chemotherapy; Modes and mechanisms of action; Organic sulfur compounds from Allium species

Indexed keywords

AJOENE; ALLICIN; ALLYL SULFIDE; ALLYLMETHYL SULFIDE; ALLYLMETHYL TRISULFIDE; CYTOCHROME P450 1A1; CYTOCHROME P450 2B1; CYTOCHROME P450 2E1; CYTOCHROME P450 3A1; DIALLYL DISULFIDE; DIALLYL TETRASULFIDE; DIALLYL TRISULFIDE; DIMETHYL TRISULFIDE; DIPROPYL DISULFIDE; DIPROPYL SULFIDE; DIPROPYL TETRASULFIDE; DIPROPYL TRISULFIDE; GLUTATHIONE TRANSFERASE; GLYCOPROTEIN P; ORGANOSULFUR DERIVATIVE; PROPYLMETHYL SULFIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); S ALLYLCYSTEINE; S ALLYLMERCAPTOCYSTEINE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 67651172829     PISSN: 15687767     EISSN: 1572980X     Source Type: Journal    
DOI: 10.1007/s11101-009-9122-z     Document Type: Article
Times cited : (30)

References (150)
  • 1
    • 0030029823 scopus 로고    scopus 로고
    • Therapeutic actions of garlic constituents
    • 10.1002/(SICI)1098-1128(199601)16:1<111::AID-MED4>3.0.CO;2-5
    • KC Agarwal 1996 Therapeutic actions of garlic constituents Med Res Rev 16 111 124 10.1002/(SICI)1098-1128(199601)16:1<111::AID-MED4>3.0.CO;2-5
    • (1996) Med Res Rev , vol.16 , pp. 111-124
    • Agarwal, K.C.1
  • 2
    • 34547128612 scopus 로고    scopus 로고
    • Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: Implications for cancer prevention
    • 10.1016/j.fct.2007.02.029
    • MK Agarwal M Iqbal M Athar 2007 Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: implications for cancer prevention Food Chem Toxicol 45 1634 1640 10.1016/j.fct.2007.02.029
    • (2007) Food Chem Toxicol , vol.45 , pp. 1634-1640
    • Agarwal, M.K.1    Iqbal, M.2    Athar, M.3
  • 3
    • 15044361086 scopus 로고    scopus 로고
    • Suppression of the nuclear factor-kappa B activation pathway by spice-derived phytochemicals: Reasoning for seasoning
    • 10.1196/annals.1329.054
    • BB Aggarwal S Shishodia 2004 Suppression of the nuclear factor-kappa B activation pathway by spice-derived phytochemicals: reasoning for seasoning Ann N Y Acad Sci 1030 434 441 10.1196/annals.1329.054
    • (2004) Ann N y Acad Sci , vol.1030 , pp. 434-441
    • Aggarwal, B.B.1    Shishodia, S.2
  • 5
    • 0037473080 scopus 로고    scopus 로고
    • Ajoene-induced cell death in human promyeloleukemic cells does not require JNK but is amplified by the inhibition of ERK
    • 10.1038/sj.onc.1206161
    • DS Antlsperger VM Dirsch D Ferreira JL Su ML Kuo AM Vollmar 2003 Ajoene-induced cell death in human promyeloleukemic cells does not require JNK but is amplified by the inhibition of ERK Oncogene 22 582 589 10.1038/sj.onc.1206161
    • (2003) Oncogene , vol.22 , pp. 582-589
    • Antlsperger, D.S.1    Dirsch, V.M.2    Ferreira, D.3    Su, J.L.4    Kuo, M.L.5    Vollmar, A.M.6
  • 6
    • 33744910333 scopus 로고    scopus 로고
    • C-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells
    • 10.1158/0008-5472.CAN-06-0356
    • J Antosiewicz A Herman-Antosiewicz SW Marynowski SV Singh 2006 c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells Cancer Res 66 5379 5386 10.1158/0008-5472.CAN-06-0356
    • (2006) Cancer Res , vol.66 , pp. 5379-5386
    • Antosiewicz, J.1    Herman-Antosiewicz, A.2    Marynowski, S.W.3    Singh, S.V.4
  • 7
    • 33745541339 scopus 로고    scopus 로고
    • Antithrombotic and anticancer effects of garlic-derived sulfur compounds: A review
    • T Ariga T Seki 2006 Antithrombotic and anticancer effects of garlic-derived sulfur compounds: a review Biofactors 26 93 103 10.1002/biof.5520260201 (Pubitemid 43979362)
    • (2006) BioFactors , vol.26 , Issue.2 , pp. 93-103
    • Ariga, T.1    Seki, T.2
  • 8
    • 3042814442 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein-mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver
    • 10.1093/carcin/bgh060
    • A Arora K Seth Y Shukla 2004 Reversal of P-glycoprotein-mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver Carcinogenesis 25 941 949 10.1093/carcin/bgh060
    • (2004) Carcinogenesis , vol.25 , pp. 941-949
    • Arora, A.1    Seth, K.2    Shukla, Y.3
  • 10
    • 0035731067 scopus 로고    scopus 로고
    • S-allylcysteine, a garlic constituent, inhibits 7,12-dimethylbenz[a] anthracene-induced hamster buccal pouch carcinogenesis
    • S Balasenthil CR Ramachandran S Nagini 2001 S-allylcysteine, a garlic constituent, inhibits 7, 12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis Nutr Cancer 40 165 172 10.1207/S15327914NC402-13 (Pubitemid 34274923)
    • (2001) Nutrition and Cancer , vol.40 , Issue.2 , pp. 165-172
    • Balasenthil, S.1    Ramachandran, C.R.2    Nagini, S.3
  • 11
    • 0035986733 scopus 로고    scopus 로고
    • Apoptosis induction by S-allylcysteine, a garlic constituent, during 7, 12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis
    • 10.1002/cbf.967
    • S Balasenthil KS Rao S Nagini 2002 Apoptosis induction by S-allylcysteine, a garlic constituent, during 7, 12-dimethylbenz[a]anthracene- induced hamster buccal pouch carcinogenesis Cell Biochem Funct 20 263 268 10.1002/cbf.967
    • (2002) Cell Biochem Funct , vol.20 , pp. 263-268
    • Balasenthil, S.1    Rao, K.S.2    Nagini, S.3
  • 13
    • 33747753776 scopus 로고    scopus 로고
    • Free-radical scavenging capacity and antioxidant properties of some selected onions (Allium cepa L.) and garlic (Allium sativum L.) extracts
    • 10.1590/S1516-89132005000600011
    • N Benkeblia 2005 Free-radical scavenging capacity and antioxidant properties of some selected onions (Allium cepa L.) and garlic (Allium sativum L.) extracts Braz Arch Biol Technol 48 753 759 10.1590/S1516-89132005000600011
    • (2005) Braz Arch Biol Technol , vol.48 , pp. 753-759
    • Benkeblia, N.1
  • 14
    • 67651167463 scopus 로고    scopus 로고
    • Allium thiosulfinates: Chemistry, biological properties and their potential utilization in food preservation
    • N Benkeblia V Lanzotti 2007 Allium thiosulfinates: chemistry, biological properties and their potential utilization in food preservation Food 1 193 201
    • (2007) Food , vol.1 , pp. 193-201
    • Benkeblia, N.1    Lanzotti, V.2
  • 16
    • 0026756541 scopus 로고
    • The organosulfur chemistry of the genus Allium-implications for the organic chemistry of sulfur
    • 10.1002/anie.199211351
    • E Block 1992 The organosulfur chemistry of the genus Allium-implications for the organic chemistry of sulfur Angew Chem Int Ed Engl 31 1135 1178 10.1002/anie.199211351
    • (1992) Angew Chem Int Ed Engl , vol.31 , pp. 1135-1178
    • Block, E.1
  • 17
    • 44949123878 scopus 로고    scopus 로고
    • In: Bowman B, Russell R (eds) ILSI Press, Washington, DC
    • Blumberg J, Milbury P (2006) In: Bowman B, Russell R (eds) Present knowledge in nutrition. ILSI Press, Washington, DC, pp 361-370
    • (2006) Present Knowledge in Nutrition , pp. 361-370
    • Blumberg, J.1    Milbury, P.2
  • 18
    • 0036221283 scopus 로고    scopus 로고
    • Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells
    • FG Bottone Jr SJ Baek JB Nixon TE Eling 2002 Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells J Nutr 132 773 778 (Pubitemid 34275081)
    • (2002) Journal of Nutrition , vol.132 , Issue.4 , pp. 773-778
    • Bottone Jr., F.G.1    Baek, S.J.2    Nixon, J.B.3    Eling, T.E.4
  • 19
    • 0034035616 scopus 로고    scopus 로고
    • Metals and neuroscience
    • 10.1016/S1367-5931(99)00073-3
    • AI Bush 2000 Metals and neuroscience Curr Opin Chem Biol 4 184 191 10.1016/S1367-5931(99)00073-3
    • (2000) Curr Opin Chem Biol , vol.4 , pp. 184-191
    • Bush, A.I.1
  • 20
    • 0032446818 scopus 로고    scopus 로고
    • Garlic, onion and cereal fibre as protective factors for breast cancer: A French case-control study
    • 10.1023/A:1007512825851
    • B Challier JM Perarnau JF Viel 1998 Garlic, onion and cereal fibre as protective factors for breast cancer: a French case-control study Eur J Epidemiol 14 737 747 10.1023/A:1007512825851
    • (1998) Eur J Epidemiol , vol.14 , pp. 737-747
    • Challier, B.1    Perarnau, J.M.2    Viel, J.F.3
  • 21
    • 13044304201 scopus 로고    scopus 로고
    • Nrf2 is essential for protection against acute pulmonary injury in mice
    • 10.1073/pnas.96.22.12731
    • K Chan YW Kan 1999 Nrf2 is essential for protection against acute pulmonary injury in mice Proc Natl Acad Sci USA 96 12731 12736 10.1073/pnas.96.22.12731
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12731-12736
    • Chan, K.1    Kan, Y.W.2
  • 22
    • 27744521872 scopus 로고    scopus 로고
    • Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area
    • 10.1158/1055-9965.EPI-05-0226
    • JM Chan F Wang EA Holly 2005 Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area Cancer Epidemiol Biomarkers Prev 14 2093 2097 10.1158/1055-9965.EPI-05-0226
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 2093-2097
    • Chan, J.M.1    Wang, F.2    Holly, E.A.3
  • 23
    • 5344220933 scopus 로고    scopus 로고
    • Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: Effect of chemical structure and stress signals
    • 10.1016/j.freeradbiomed.2004.07.021
    • C Chen D Pung V Leong 2004 Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals Free Radic Biol Med 37 1578 1590 10.1016/j.freeradbiomed.2004.07.021
    • (2004) Free Radic Biol Med , vol.37 , pp. 1578-1590
    • Chen, C.1    Pung, D.2    Leong, V.3
  • 24
    • 0035897653 scopus 로고    scopus 로고
    • Homologs of gp91phox: Cloning and tissue expression of Nox3, Nox4, and Nox5
    • 10.1016/S0378-1119(01)00449-8
    • G Cheng Z Cao X Xu EG van Meir JD Lambeth 2001 Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5 Gene 269 131 140 10.1016/S0378-1119(01)00449-8
    • (2001) Gene , vol.269 , pp. 131-140
    • Cheng, G.1    Cao, Z.2    Xu, X.3    Van Meir, E.G.4    Lambeth, J.D.5
  • 25
    • 33750442231 scopus 로고    scopus 로고
    • A novel anticancer effect of garlic derivatives: Inhibition of cancer cell invasion through restoration of E-cadherin expression
    • 10.1093/carcin/bgl054
    • Q Chu MT Ling H Feng 2006 A novel anticancer effect of garlic derivatives: inhibition of cancer cell invasion through restoration of E-cadherin expression Carcinogenesis 27 2180 2189 10.1093/carcin/bgl054
    • (2006) Carcinogenesis , vol.27 , pp. 2180-2189
    • Chu, Q.1    Ling, M.T.2    Feng, H.3
  • 26
    • 44449140859 scopus 로고    scopus 로고
    • Mechanisms of ROS modulated cell survival during carcinogenesis
    • 10.1016/j.canlet.2008.02.029
    • JS Clerkin R Naughton C Quiney TG Cotter 2008 Mechanisms of ROS modulated cell survival during carcinogenesis Cancer Lett 266 30 36 10.1016/j.canlet. 2008.02.029
    • (2008) Cancer Lett , vol.266 , pp. 30-36
    • Clerkin, J.S.1    Naughton, R.2    Quiney, C.3    Cotter, T.G.4
  • 27
    • 34548152518 scopus 로고    scopus 로고
    • Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells
    • 10.1002/cncr.22888
    • A Das NL Banik SK Ray 2007 Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells Cancer 110 1083 1095 10.1002/cncr.22888
    • (2007) Cancer , vol.110 , pp. 1083-1095
    • Das, A.1    Banik, N.L.2    Ray, S.K.3
  • 28
    • 34548456881 scopus 로고    scopus 로고
    • Dietary histone deacetylase inhibitors: From cells to mice to man
    • 10.1016/j.semcancer.2007.04.001
    • RH Dashwood E Ho 2007 Dietary histone deacetylase inhibitors: from cells to mice to man Semin Cancer Biol 17 363 369 10.1016/j.semcancer.2007.04.001
    • (2007) Semin Cancer Biol , vol.17 , pp. 363-369
    • Dashwood, R.H.1    Ho, E.2
  • 29
    • 25144464000 scopus 로고    scopus 로고
    • Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic
    • 10.1016/j.fct.2005.05.018
    • DM Davenport MJ Wargovich 2005 Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic Food Chem Toxicol 43 1753 1762 10.1016/j.fct.2005.05.018
    • (2005) Food Chem Toxicol , vol.43 , pp. 1753-1762
    • Davenport, D.M.1    Wargovich, M.J.2
  • 30
    • 15444378850 scopus 로고    scopus 로고
    • An overview of the antifungal properties of allicin and its breakdown products-the possibility of a safe and effective antifungal prophylactic
    • 10.1111/j.1439-0507.2004.01076.x
    • SR Davis 2005 An overview of the antifungal properties of allicin and its breakdown products-the possibility of a safe and effective antifungal prophylactic Mycoses 48 95 100 10.1111/j.1439-0507.2004.01076.x
    • (2005) Mycoses , vol.48 , pp. 95-100
    • Davis, S.R.1
  • 31
    • 15044350623 scopus 로고    scopus 로고
    • A beginner's guide to NF-kappaB signaling pathways
    • 10.1196/annals.1329.002
    • S Delhalle R Blasius M Dicato M Diederich 2004 A beginner's guide to NF-kappaB signaling pathways Ann N Y Acad Sci 1030 1 13 10.1196/annals.1329.002
    • (2004) Ann N y Acad Sci , vol.1030 , pp. 1-13
    • Delhalle, S.1    Blasius, R.2    Dicato, M.3    Diederich, M.4
  • 32
    • 36649012382 scopus 로고    scopus 로고
    • Is garlic a promising food for benign prostatic hyperplasia and prostate cancer?
    • 10.1002/mnfr.200600302
    • E Devrim I Durak 2007 Is garlic a promising food for benign prostatic hyperplasia and prostate cancer? Mol Nutr Food Res 51 1319 1323 10.1002/mnfr.200600302
    • (2007) Mol Nutr Food Res , vol.51 , pp. 1319-1323
    • Devrim, E.1    Durak, I.2
  • 33
    • 0031976715 scopus 로고    scopus 로고
    • Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor κB
    • VM Dirsch AL Gerbes AM Vollmar 1998 Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappa B Mol Pharmacol 53 402 407 (Pubitemid 28162860)
    • (1998) Molecular Pharmacology , vol.53 , Issue.3 , pp. 402-407
    • Dirsch, V.M.1    Gerbes, A.L.2    Vollmar, A.M.3
  • 34
    • 85009834484 scopus 로고    scopus 로고
    • Ajoene, an experimental anti-leukemic drug: Mechanism of cell death
    • DOI 10.1038/sj/leu/2402337
    • VM Dirsch DS Antlsperger H Hentze AM Vollmar 2002 Ajoene, an experimental anti-leukemic drug: mechanism of cell death Leukemia 16 74 83 10.1038/sj.leu.2402337 (Pubitemid 34105602)
    • (2002) Leukemia , vol.16 , Issue.1 , pp. 74-83
    • Dirsch, V.M.1    Antlsperger, D.S.M.2    Hentze, H.3    Vollmar, A.M.4
  • 35
    • 0035868469 scopus 로고    scopus 로고
    • SIN-1-induced DNA damage in isolated human peripheral blood lymphocytes as assessed by single cell gel electrophoresis (comet assay)
    • 10.1016/S0891-5849(00)00511-6
    • PT Doulias A Barbouti D Galaris H Ischiropoulos 2001 SIN-1-induced DNA damage in isolated human peripheral blood lymphocytes as assessed by single cell gel electrophoresis (comet assay) Free Radic Biol Med 30 679 685 10.1016/S0891-5849(00)00511-6
    • (2001) Free Radic Biol Med , vol.30 , pp. 679-685
    • Doulias, P.T.1    Barbouti, A.2    Galaris, D.3    Ischiropoulos, H.4
  • 36
    • 3242755145 scopus 로고    scopus 로고
    • Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines
    • 10.1093/carcin/bgh123
    • N Druesne A Pagniez C Mayeur 2004 Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines Carcinogenesis 25 1227 1236 10.1093/carcin/bgh123
    • (2004) Carcinogenesis , vol.25 , pp. 1227-1236
    • Druesne, N.1    Pagniez, A.2    Mayeur, C.3
  • 38
    • 0028345763 scopus 로고
    • Reactive oxygen species in tumorigenesis
    • DI Feig TM Reid LA Loeb 1994 Reactive oxygen species in tumorigenesis Cancer Res 54 1890s 1894s (Pubitemid 24132140)
    • (1994) Cancer Research , vol.54 , Issue.SUPPL.
    • Feig, D.I.1    Reid, T.M.2    Loeb, L.A.3
  • 39
    • 0023761696 scopus 로고
    • Recognition and destruction of neoplastic cells by activated macrophages: Discrimination of altered self
    • DOI 10.1016/0304-419X(88)90009-1
    • IJ Fidler AJ Schroit 1988 Recognition and destruction of neoplastic cells by activated macrophages: discrimination of altered self Biochim Biophys Acta 948 151 173 (Pubitemid 18263873)
    • (1988) Biochimica et Biophysica Acta - Reviews on Cancer , vol.948 , Issue.2 , pp. 151-173
    • Fidler, I.J.1    Schroit, A.J.2
  • 40
    • 0141842655 scopus 로고    scopus 로고
    • 2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide
    • G Filomeni K Aquilano G Rotilio MR Ciriolo 2003 Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide Cancer Res 63 5940 5949 (Pubitemid 37187495)
    • (2003) Cancer Research , vol.63 , Issue.18 , pp. 5940-5949
    • Filomeni, G.1    Aquilano, K.2    Rotilio, G.3    Ciriolo, M.R.4
  • 41
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • 10.1038/35041687
    • T Finkel NJ Holbrook 2000 Oxidants, oxidative stress and the biology of ageing Nature 408 239 247 10.1038/35041687
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 42
    • 34249094270 scopus 로고    scopus 로고
    • Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2
    • 10.1124/dmd.106.014340
    • CD Fisher LM Augustine JM Maher 2007 Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2 Drug Metab Dispos 35 995 1000 10.1124/dmd.106.014340
    • (2007) Drug Metab Dispos , vol.35 , pp. 995-1000
    • Fisher, C.D.1    Augustine, L.M.2    Maher, J.M.3
  • 43
    • 0035089498 scopus 로고    scopus 로고
    • Garlic and cancer: A critical review of the epidemiologic literature
    • AT Fleischauer L Arab 2001 Garlic and cancer: a critical review of the epidemiologic literature J Nutr 131 1032S 1040S (Pubitemid 32197292)
    • (2001) Journal of Nutrition , vol.131 , Issue.SUPPL.
    • Fleischauer, A.T.1    Arab, L.2
  • 44
    • 16444384314 scopus 로고    scopus 로고
    • Chemoprotective effect of diallyl trisulfide from garlic against carbon tetrachloride-induced acute liver injury of rats
    • T Fukao T Hosono S Misawa T Seki T Ariga 2004 Chemoprotective effect of diallyl trisulfide from garlic against carbon tetrachloride-induced acute liver injury of rats Biofactors 21 171 174 10.1002/biof.552210135 (Pubitemid 40921849)
    • (2004) BioFactors , vol.21 , Issue.1-4 , pp. 171-174
    • Fukao, T.1    Hosono, T.2    Misawa, S.3    Seki, T.4    Ariga, T.5
  • 45
    • 1642367217 scopus 로고    scopus 로고
    • The effects of allyl sulfides on the induction of phase II detoxification enzymes and liver injury by carbon tetrachloride
    • 10.1016/j.fct.2003.12.010
    • T Fukao T Hosono S Misawa T Seki T Ariga 2004 The effects of allyl sulfides on the induction of phase II detoxification enzymes and liver injury by carbon tetrachloride Food Chem Toxicol 42 743 749 10.1016/j.fct.2003.12.010
    • (2004) Food Chem Toxicol , vol.42 , pp. 743-749
    • Fukao, T.1    Hosono, T.2    Misawa, S.3    Seki, T.4    Ariga, T.5
  • 47
    • 44449145862 scopus 로고    scopus 로고
    • Redox signaling and cancer: The role of "labile" iron
    • 10.1016/j.canlet.2008.02.038
    • D Galaris V Skiada A Barbouti 2008 Redox signaling and cancer: the role of "labile" iron Cancer Lett 266 21 29 10.1016/j.canlet.2008.02.038
    • (2008) Cancer Lett , vol.266 , pp. 21-29
    • Galaris, D.1    Skiada, V.2    Barbouti, A.3
  • 48
    • 0032812158 scopus 로고    scopus 로고
    • Protective effect of allium vegetables against both esophageal and stomach cancer: A simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China
    • CM Gao T Takezaki JH Ding MS Li K Tajima 1999 Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China Jpn J Cancer Res 90 614 621 (Pubitemid 29332919)
    • (1999) Japanese Journal of Cancer Research , vol.90 , Issue.6 , pp. 614-621
    • Gao, C.-M.1    Takezaki, T.2    Ding, J.-H.3    Li, M.-S.4    Tajima, K.5
  • 49
    • 0030924820 scopus 로고    scopus 로고
    • S-allyl cysteine inhibits activation of nuclear factor kappa B in human T cells
    • 10.1016/S0891-5849(97)00006-3
    • Z Geng Y Rong BH Lau 1997 S-allyl cysteine inhibits activation of nuclear factor kappa B in human T cells Free Radic Biol Med 23 345 350 10.1016/S0891-5849(97)00006-3
    • (1997) Free Radic Biol Med , vol.23 , pp. 345-350
    • Geng, Z.1    Rong, Y.2    Lau, B.H.3
  • 50
    • 33646405748 scopus 로고    scopus 로고
    • Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    • 10.1002/ijc.21678
    • CA Gonzalez G Pera A Agudo 2006 Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) Int J Cancer 118 2559 2566 10.1002/ijc.21678
    • (2006) Int J Cancer , vol.118 , pp. 2559-2566
    • Gonzalez, C.A.1    Pera, G.2    Agudo, A.3
  • 51
    • 0023951396 scopus 로고
    • Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy
    • FP Guengerich 1988 Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy Cancer Res 48 2946 2954 (Pubitemid 18141876)
    • (1988) Cancer Research , vol.48 , Issue.11 , pp. 2946-2954
    • Guengerich, F.P.1
  • 52
    • 0026636441 scopus 로고
    • Free radicals, antioxidants, and human disease: Where are we now?
    • B Halliwell JM Gutteridge CE Cross 1992 Free radicals, antioxidants, and human disease: where are we now? J Lab Clin Med 119 598 620
    • (1992) J Lab Clin Med , vol.119 , pp. 598-620
    • Halliwell, B.1    Gutteridge, J.M.2    Cross, C.E.3
  • 53
    • 0024425887 scopus 로고
    • Checkpoints: controls that ensure the order of cell cycle events
    • LH Hartwell TA Weinert 1989 Checkpoints: controls that ensure the order of cell cycle events Science 246 629 634 10.1126/science.2683079 (Pubitemid 19283354)
    • (1989) Science , vol.246 , Issue.4930 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 54
    • 2442423162 scopus 로고    scopus 로고
    • Ajoene (natural garlic compound): A new anti-leukaemia agent for AML therapy
    • 10.1016/j.leukres.2003.10.008
    • HT Hassan 2004 Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy Leuk Res 28 667 671 10.1016/j.leukres.2003.10.008
    • (2004) Leuk Res , vol.28 , pp. 667-671
    • Hassan, H.T.1
  • 55
    • 0042427571 scopus 로고    scopus 로고
    • Immunomodulatory affect of R10 fraction of garlic extract on natural killer activity
    • 10.1016/S1567-5769(03)00161-9
    • ZM Hassan R Yaraee N Zare T Ghazanfari AH Sarraf Nejad B Nazori 2003 Immunomodulatory affect of R10 fraction of garlic extract on natural killer activity Int Immunopharmacol 3 1483 1489 10.1016/S1567-5769(03)00161-9
    • (2003) Int Immunopharmacol , vol.3 , pp. 1483-1489
    • Hassan, Z.M.1    Yaraee, R.2    Zare, N.3    Ghazanfari, T.4    Sarraf Nejad, A.H.5    Nazori, B.6
  • 56
    • 0036151383 scopus 로고    scopus 로고
    • Hypochlorite-induced damage to DNA, RNA, and polynucleotides: Formation of chloramines and nitrogen-centered radicals
    • 10.1021/tx015548d
    • CL Hawkins MJ Davies 2002 Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals Chem Res Toxicol 15 83 92 10.1021/tx015548d
    • (2002) Chem Res Toxicol , vol.15 , pp. 83-92
    • Hawkins, C.L.1    Davies, M.J.2
  • 57
    • 5144220818 scopus 로고    scopus 로고
    • Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: A review
    • 10.1016/j.mrfmmm.2004.04.016
    • A Herman-Antosiewicz SV Singh 2004 Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review Mutat Res 555 121 131 10.1016/j.mrfmmm.2004.04.016
    • (2004) Mutat Res , vol.555 , pp. 121-131
    • Herman-Antosiewicz, A.1    Singh, S.V.2
  • 58
    • 34548408192 scopus 로고    scopus 로고
    • Molecular targets of cancer chemoprevention by garlic-derived organosulfides
    • 10.1111/j.1745-7254.2007.00682.x
    • A Herman-Antosiewicz AA Powolny SV Singh 2007 Molecular targets of cancer chemoprevention by garlic-derived organosulfides Acta Pharmacol Sin 28 1355 1364 10.1111/j.1745-7254.2007.00682.x
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 1355-1364
    • Herman-Antosiewicz, A.1    Powolny, A.A.2    Singh, S.V.3
  • 59
    • 34248177364 scopus 로고    scopus 로고
    • Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic
    • 10.1158/1535-7163.MCT-06-0477
    • A Herman-Antosiewicz SD Stan ER Hahm D Xiao SV Singh 2007 Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic Mol Cancer Ther 6 1249 1261 10.1158/1535-7163.MCT-06-0477
    • (2007) Mol Cancer Ther , vol.6 , pp. 1249-1261
    • Herman-Antosiewicz, A.1    Stan, S.D.2    Hahm, E.R.3    Xiao, D.4    Singh, S.V.5
  • 60
    • 0035078570 scopus 로고    scopus 로고
    • S-allyl cysteine reduces oxidant load in cells involved in the atherogenic process
    • SE Ho N Ide BH Lau 2001 S-allyl cysteine reduces oxidant load in cells involved in the atherogenic process Phytomedicine 8 39 46 10.1078/0944-7113- 00005 (Pubitemid 32242091)
    • (2001) Phytomedicine , vol.8 , Issue.1 , pp. 39-46
    • Ho, S.E.1    Ide, N.2    Lau, B.H.S.3
  • 61
    • 0034734611 scopus 로고    scopus 로고
    • Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines
    • YS Hong YA Ham JH Choi J Kim 2000 Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines Exp Mol Med 32 127 134
    • (2000) Exp Mol Med , vol.32 , pp. 127-134
    • Hong, Y.S.1    Ham, Y.A.2    Choi, J.H.3    Kim, J.4
  • 62
    • 29244484434 scopus 로고    scopus 로고
    • Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of beta-tubulin
    • 10.1074/jbc.M507127200
    • T Hosono T Fukao J Ogihara 2005 Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of beta-tubulin J Biol Chem 280 41487 41493 10.1074/jbc.M507127200
    • (2005) J Biol Chem , vol.280 , pp. 41487-41493
    • Hosono, T.1    Fukao, T.2    Ogihara, J.3
  • 63
    • 34250191113 scopus 로고    scopus 로고
    • Garlic-derived S-allylmercaptocysteine is a novel in vivo antimetastatic agent for androgen-independent prostate cancer
    • 10.1158/1078-0432.CCR-06-2074
    • EW Howard MT Ling CW Chua HW Cheung X Wang YC Wong 2007 Garlic-derived S-allylmercaptocysteine is a novel in vivo antimetastatic agent for androgen-independent prostate cancer Clin Cancer Res 13 1847 1856 10.1158/1078-0432.CCR-06-2074
    • (2007) Clin Cancer Res , vol.13 , pp. 1847-1856
    • Howard, E.W.1    Ling, M.T.2    Chua, C.W.3    Cheung, H.W.4    Wang, X.5    Wong, Y.C.6
  • 65
    • 0035126519 scopus 로고    scopus 로고
    • Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-κB activation
    • N Ide BH Lau 2001 Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-kappa B activation J Nutr 131 1020S 1026S (Pubitemid 32195001)
    • (2001) Journal of Nutrition , vol.131 , Issue.SUPPL.
    • Ide, N.1    Lau, B.H.S.2
  • 66
    • 33751439570 scopus 로고    scopus 로고
    • A scent of therapy: Pharmacological implications of natural products containing redox-active sulfur atoms
    • 10.1039/b609523m
    • C Jacob 2006 A scent of therapy: pharmacological implications of natural products containing redox-active sulfur atoms Nat Prod Rep 23 851 863 10.1039/b609523m
    • (2006) Nat Prod Rep , vol.23 , pp. 851-863
    • Jacob, C.1
  • 67
    • 45249120583 scopus 로고    scopus 로고
    • The chemistry behind redox regulation with a focus on sulphur redox systems
    • 10.1111/j.1399-3054.2008.01080.x
    • C Jacob A Anwar 2008 The chemistry behind redox regulation with a focus on sulphur redox systems Physiol Plant 133 469 480 10.1111/j.1399-3054.2008. 01080.x
    • (2008) Physiol Plant , vol.133 , pp. 469-480
    • Jacob, C.1    Anwar, A.2
  • 68
    • 0042314356 scopus 로고    scopus 로고
    • Sulfur and selenium: The role of oxidation state in protein structure and function
    • 10.1002/anie.200300573
    • C Jacob GI Giles NM Giles H Sies 2003 Sulfur and selenium: the role of oxidation state in protein structure and function Angew Chem Int Ed Engl 42 4742 4758 10.1002/anie.200300573
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 4742-4758
    • Jacob, C.1    Giles, G.I.2    Giles, N.M.3    Sies, H.4
  • 69
    • 33750604604 scopus 로고    scopus 로고
    • Aspects of the biological redox chemistry of cysteine: From simple redox responses to sophisticated signalling pathways
    • 10.1515/BC.2006.174
    • C Jacob I Knight PG Winyard 2006 Aspects of the biological redox chemistry of cysteine: from simple redox responses to sophisticated signalling pathways Biol Chem 387 1385 1397 10.1515/BC.2006.174
    • (2006) Biol Chem , vol.387 , pp. 1385-1397
    • Jacob, C.1    Knight, I.2    Winyard, P.G.3
  • 70
    • 34547133997 scopus 로고    scopus 로고
    • The bioactivity of processed garlic (Allium sativum L.) as shown in vitro and in vivo studies on rats
    • 10.1016/j.fct.2007.02.028
    • Z Jastrzebski H Leontowicz M Leontowicz 2007 The bioactivity of processed garlic (Allium sativum L.) as shown in vitro and in vivo studies on rats Food Chem Toxicol 45 1626 1633 10.1016/j.fct.2007.02.028
    • (2007) Food Chem Toxicol , vol.45 , pp. 1626-1633
    • Jastrzebski, Z.1    Leontowicz, H.2    Leontowicz, M.3
  • 71
    • 33947174588 scopus 로고    scopus 로고
    • Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells
    • 10.1007/s10495-006-0024-x
    • S Karmakar NL Banik SJ Patel SK Ray 2007 Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells Apoptosis 12 671 684 10.1007/s10495-006-0024-x
    • (2007) Apoptosis , vol.12 , pp. 671-684
    • Karmakar, S.1    Banik, N.L.2    Patel, S.J.3    Ray, S.K.4
  • 72
    • 10944248830 scopus 로고    scopus 로고
    • Endogenous formation of novel halogenated 2′-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation
    • 10.1074/jbc.M408210200
    • Y Kawai H Morinaga H Kondo 2004 Endogenous formation of novel halogenated 2′-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation J Biol Chem 279 51241 51249 10.1074/jbc.M408210200
    • (2004) J Biol Chem , vol.279 , pp. 51241-51249
    • Kawai, Y.1    Morinaga, H.2    Kondo, H.3
  • 74
    • 34250721692 scopus 로고    scopus 로고
    • Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak
    • 10.1158/1535-7163.MCT-06-0754
    • YA Kim D Xiao H Xiao 2007 Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak Mol Cancer Ther 6 1599 1609 10.1158/1535-7163.MCT-06-0754
    • (2007) Mol Cancer Ther , vol.6 , pp. 1599-1609
    • Kim, Y.A.1    Xiao, D.2    Xiao, H.3
  • 75
    • 1342344820 scopus 로고    scopus 로고
    • The role of oxidative stress in carcinogenesis
    • 10.1146/annurev.pharmtox.44.101802.121851
    • JE Klaunig LM Kamendulis 2004 The role of oxidative stress in carcinogenesis Annu Rev Pharmacol Toxicol 44 239 267 10.1146/annurev.pharmtox. 44.101802.121851
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 239-267
    • Klaunig, J.E.1    Kamendulis, L.M.2
  • 77
    • 0036149375 scopus 로고    scopus 로고
    • Induction of apoptosis by diallyl disulfide through activation of caspase-3 in human leukemia HL-60 cells
    • 10.1016/S0006-2952(01)00860-7
    • KB Kwon SJ Yoo DG Ryu 2002 Induction of apoptosis by diallyl disulfide through activation of caspase-3 in human leukemia HL-60 cells Biochem Pharmacol 63 41 47 10.1016/S0006-2952(01)00860-7
    • (2002) Biochem Pharmacol , vol.63 , pp. 41-47
    • Kwon, K.B.1    Yoo, S.J.2    Ryu, D.G.3
  • 78
    • 28644434661 scopus 로고    scopus 로고
    • Bioactive saponins from Allium and Aster plants
    • 10.1007/s11101-005-1254-1
    • V Lanzotti 2005 Bioactive saponins from Allium and Aster plants Phytochem Rev 4 95 110 10.1007/s11101-005-1254-1
    • (2005) Phytochem Rev , vol.4 , pp. 95-110
    • Lanzotti, V.1
  • 79
    • 33645829809 scopus 로고    scopus 로고
    • The analysis of onion and garlic
    • 10.1016/j.chroma.2005.12.016
    • V Lanzotti 2006 The analysis of onion and garlic J Chromatogr A 1112 3 22 10.1016/j.chroma.2005.12.016
    • (2006) J Chromatogr A , vol.1112 , pp. 3-22
    • Lanzotti, V.1
  • 81
    • 44949179401 scopus 로고    scopus 로고
    • Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?
    • 10.1093/jnci/djn148
    • BD Lawenda KM Kelly EJ Ladas SM Sagar A Vickers JB Blumberg 2008 Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? J Natl Cancer Inst 100 773 783 10.1093/jnci/djn148
    • (2008) J Natl Cancer Inst , vol.100 , pp. 773-783
    • Lawenda, B.D.1    Kelly, K.M.2    Ladas, E.J.3    Sagar, S.M.4    Vickers, A.5    Blumberg, J.B.6
  • 84
    • 33947404836 scopus 로고    scopus 로고
    • Garlic oil prevents tributyltin-induced oxidative damage in vivo and in vitro
    • HG Liu LH Xu 2007 Garlic oil prevents tributyltin-induced oxidative damage in vivo and in vitro J Food Prot 70 716 721
    • (2007) J Food Prot , vol.70 , pp. 716-721
    • Liu, H.G.1    Xu, L.H.2
  • 85
    • 33744459527 scopus 로고    scopus 로고
    • DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kappaB activation in RAW 264.7 macrophages
    • 10.1021/jf060043k
    • KL Liu HW Chen RY Wang YP Lei LY Sheen CK Lii 2006 DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kappaB activation in RAW 264.7 macrophages J Agric Food Chem 54 3472 3478 10.1021/jf060043k
    • (2006) J Agric Food Chem , vol.54 , pp. 3472-3478
    • Liu, K.L.1    Chen, H.W.2    Wang, R.Y.3    Lei, Y.P.4    Sheen, L.Y.5    Lii, C.K.6
  • 86
    • 0029886786 scopus 로고    scopus 로고
    • Cancer risk and oxidative DNA damage in man
    • DOI 10.1007/s001090050031
    • S Loft HE Poulsen 1996 Cancer risk and oxidative DNA damage in man J Mol Med 74 297 312 10.1007/BF00207507 (Pubitemid 26195901)
    • (1996) Journal of Molecular Medicine , vol.74 , Issue.6 , pp. 297-312
    • Loft, S.1    Poulsen, H.E.2
  • 87
    • 4043133743 scopus 로고    scopus 로고
    • Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells
    • 10.1016/j.fct.2003.06.001
    • HF Lu CC Sue CS Yu SC Chen GW Chen JG Chung 2004 Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells Food Chem Toxicol 42 1543 1552 10.1016/j.fct.2003.06.001
    • (2004) Food Chem Toxicol , vol.42 , pp. 1543-1552
    • Lu, H.F.1    Sue, C.C.2    Yu, C.S.3    Chen, S.C.4    Chen, G.W.5    Chung, J.G.6
  • 91
    • 0033973286 scopus 로고    scopus 로고
    • The mode of action of allicin: Its ready permeability through phospholipid membranes may contribute to its biological activity
    • 10.1016/S0005-2736(99)00174-1
    • T Miron A Rabinkov D Mirelman M Wilchek L Weiner 2000 The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity Biochim Biophys Acta 1463 20 30 10.1016/S0005- 2736(99)00174-1
    • (2000) Biochim Biophys Acta , vol.1463 , pp. 20-30
    • Miron, T.1    Rabinkov, A.2    Mirelman, D.3    Wilchek, M.4    Weiner, L.5
  • 92
    • 2342611976 scopus 로고    scopus 로고
    • Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: Role of reoxygenation, free radicals, and stress granules
    • 10.1016/S1535-6108(04)00115-1
    • BJ Moeller Y Cao CY Li MW Dewhirst 2004 Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules Cancer Cell 5 429 441 10.1016/S1535-6108(04)00115- 1
    • (2004) Cancer Cell , vol.5 , pp. 429-441
    • Moeller, B.J.1    Cao, Y.2    Li, C.Y.3    Dewhirst, M.W.4
  • 93
    • 34250747473 scopus 로고    scopus 로고
    • Polysulfides as biologically active ingredients of garlic
    • 10.1039/b703832a
    • U Munchberg A Anwar S Mecklenburg C Jacob 2007 Polysulfides as biologically active ingredients of garlic Org Biomol Chem 5 1505 1518 10.1039/b703832a
    • (2007) Org Biomol Chem , vol.5 , pp. 1505-1518
    • Munchberg, U.1    Anwar, A.2    Mecklenburg, S.3    Jacob, C.4
  • 94
    • 0037403325 scopus 로고    scopus 로고
    • Comparative effects of mono-, di-, tri-, and tetrasulfides derived from plants of the Allium family: Redox cycling in vitro and hemolytic activity and Phase 2 enzyme induction in vivo
    • 10.1016/S0891-5849(03)00144-8
    • R Munday JS Munday CM Munday 2003 Comparative effects of mono-, di-, tri-, and tetrasulfides derived from plants of the Allium family: redox cycling in vitro and hemolytic activity and Phase 2 enzyme induction in vivo Free Radic Biol Med 34 1200 1211 10.1016/S0891-5849(03)00144-8
    • (2003) Free Radic Biol Med , vol.34 , pp. 1200-1211
    • Munday, R.1    Munday, J.S.2    Munday, C.M.3
  • 95
    • 34249901047 scopus 로고    scopus 로고
    • Diallyl tetrasulfide modulates the cadmium-induced impairment of membrane bound enzymes in rats
    • P Murugavel L Pari 2007 Diallyl tetrasulfide modulates the cadmium-induced impairment of membrane bound enzymes in rats J Basic Clin Physiol Pharmacol 18 37 48 (Pubitemid 46867342)
    • (2007) Journal of Basic and Clinical Physiology and Pharmacology , vol.18 , Issue.1 , pp. 37-48
    • Murugavel, P.1    Pari, L.2
  • 96
    • 34249876524 scopus 로고    scopus 로고
    • Effects of diallyl tetrasulfide on cadmium-induced oxidative damage in the liver of rats
    • 10.1177/0960327107073810
    • P Murugavel L Pari 2007 Effects of diallyl tetrasulfide on cadmium-induced oxidative damage in the liver of rats Hum Exp Toxicol 26 527 534 10.1177/0960327107073810
    • (2007) Hum Exp Toxicol , vol.26 , pp. 527-534
    • Murugavel, P.1    Pari, L.2
  • 97
    • 0033031295 scopus 로고    scopus 로고
    • Induction of reactive oxygen intermediates in human monocytes by tumour cells and their role in spontaneous monocyte cytotoxicity
    • 10.1038/sj.bjc.6690118
    • B Mytar M Siedlar M Woloszyn I Ruggiero J Pryjma M Zembala 1999 Induction of reactive oxygen intermediates in human monocytes by tumour cells and their role in spontaneous monocyte cytotoxicity Br J Cancer 79 737 743 10.1038/sj.bjc.6690118
    • (1999) Br J Cancer , vol.79 , pp. 737-743
    • Mytar, B.1    Siedlar, M.2    Woloszyn, M.3    Ruggiero, I.4    Pryjma, J.5    Zembala, M.6
  • 99
    • 34948883590 scopus 로고    scopus 로고
    • Does garlic reduce risk of colorectal cancer? A systematic review
    • SN Ngo DB Williams L Cobiac RJ Head 2007 Does garlic reduce risk of colorectal cancer? A systematic review J Nutr 137 2264 2269 (Pubitemid 47529588)
    • (2007) Journal of Nutrition , vol.137 , Issue.10 , pp. 2264-2269
    • Ngo, S.N.T.1    Williams, D.B.2    Cobiac, L.3    Head, R.J.4
  • 100
    • 44449142812 scopus 로고    scopus 로고
    • Reactive oxygen species in tumor metastasis
    • 10.1016/j.canlet.2008.02.031
    • M Nishikawa 2008 Reactive oxygen species in tumor metastasis Cancer Lett 266 53 59 10.1016/j.canlet.2008.02.031
    • (2008) Cancer Lett , vol.266 , pp. 53-59
    • Nishikawa, M.1
  • 101
    • 33745532525 scopus 로고    scopus 로고
    • Antioxidative activity and ameliorative effects of memory impairment of sulfur-containing compounds in Allium species
    • H Nishimura O Higuchi K Tateshita K Tomobe Y Okuma Y Nomura 2006 Antioxidative activity and ameliorative effects of memory impairment of sulfur-containing compounds in Allium species Biofactors 26 135 146 10.1002/biof.5520260204 (Pubitemid 43979365)
    • (2006) BioFactors , vol.26 , Issue.2 , pp. 135-146
    • Nishimura, H.1    Higuchi, O.2    Tateshita, K.3    Tomobe, K.4    Okuma, Y.5    Nomura, Y.6
  • 102
    • 1642456598 scopus 로고    scopus 로고
    • Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells
    • 10.1016/j.ejphar.2003.11.059
    • S Oommen RJ Anto G Srinivas D Karunagaran 2004 Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells Eur J Pharmacol 485 97 103 10.1016/j.ejphar.2003.11.059
    • (2004) Eur J Pharmacol , vol.485 , pp. 97-103
    • Oommen, S.1    Anto, R.J.2    Srinivas, G.3    Karunagaran, D.4
  • 103
    • 44449126104 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) in multistage carcinogenesis
    • 10.1016/j.canlet.2008.02.027
    • M Panayiotidis 2008 Reactive oxygen species (ROS) in multistage carcinogenesis Cancer Lett 266 3 5 10.1016/j.canlet.2008.02.027
    • (2008) Cancer Lett , vol.266 , pp. 3-5
    • Panayiotidis, M.1
  • 104
    • 0037205963 scopus 로고    scopus 로고
    • Role of Ca(2+) in diallyl disulfide-induced apoptotic cell death of HCT-15 cells
    • EK Park KB Kwon KI Park BH Park EC Jhee 2002 Role of Ca(2+) in diallyl disulfide-induced apoptotic cell death of HCT-15 cells Exp Mol Med 34 250 257
    • (2002) Exp Mol Med , vol.34 , pp. 250-257
    • Park, E.K.1    Kwon, K.B.2    Park, K.I.3    Park, B.H.4    Jhee, E.C.5
  • 105
    • 1842848678 scopus 로고    scopus 로고
    • Anticarcinogenic effect and modification of cytochrome P450 2E1 by dietary garlic powder in diethylnitrosamine-initiated rat hepatocarcinogenesis
    • KA Park S Kweon H Choi 2002 Anticarcinogenic effect and modification of cytochrome P450 2E1 by dietary garlic powder in diethylnitrosamine-initiated rat hepatocarcinogenesis J Biochem Mol Biol 35 615 622 (Pubitemid 43142920)
    • (2002) Journal of Biochemistry and Molecular Biology , vol.35 , Issue.6 , pp. 615-622
    • Park, K.-A.1    Kweon, S.2    Choi, H.3
  • 106
    • 19344369098 scopus 로고    scopus 로고
    • Caspase-independent cell death by allicin in human epithelial carcinoma cells: Involvement of PKA
    • DOI 10.1016/j.canlet.2004.10.009, PII S0304383504008043
    • SY Park SJ Cho HC Kwon KR Lee DK Rhee S Pyo 2005 Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA Cancer Lett 224 123 132 (Pubitemid 40720373)
    • (2005) Cancer Letters , vol.224 , Issue.1 , pp. 123-132
    • Park, S.-Y.1    Cho, S.-J.2    Kwon, H.-C.3    Lee, K.-R.4    Rhee, D.-K.5    Pyo, S.6
  • 107
    • 1042269473 scopus 로고    scopus 로고
    • Allicin stimulates lymphocytes and elicits an antitumor effect: A possible role of p21ras
    • 10.1093/intimm/dxh038
    • M Patya MA Zahalka A Vanichkin 2004 Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras Int Immunol 16 275 281 10.1093/intimm/dxh038
    • (2004) Int Immunol , vol.16 , pp. 275-281
    • Patya, M.1    Zahalka, M.A.2    Vanichkin, A.3
  • 108
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • 10.1016/j.drup.2004.01.004
    • H Pelicano D Carney P Huang 2004 ROS stress in cancer cells and therapeutic implications Drug Resist Updat 7 97 110 10.1016/j.drup.2004.01.004
    • (2004) Drug Resist Updat , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 109
    • 0032986046 scopus 로고    scopus 로고
    • High doses of multiple antioxidant vitamins: Essential ingredients in improving the efficacy of standard cancer therapy
    • KN Prasad A Kumar V Kochupillai WC Cole 1999 High doses of multiple antioxidant vitamins: essential ingredients in improving the efficacy of standard cancer therapy J Am Coll Nutr 18 13 25 (Pubitemid 29088681)
    • (1999) Journal of the American College of Nutrition , vol.18 , Issue.1 , pp. 13-25
    • Prasad, K.N.1    Kumar, A.2    Kochupillai, V.3    Cole, W.C.4
  • 110
    • 44849119311 scopus 로고    scopus 로고
    • Regulation of oxidative stress-mediated apoptosis by diallyl sulfide in DMBA-exposed Swiss mice
    • 10.1177/0960327108088978
    • S Prasad N Kalra S Srivastava Y Shukla 2008 Regulation of oxidative stress-mediated apoptosis by diallyl sulfide in DMBA-exposed Swiss mice Hum Exp Toxicol 27 55 63 10.1177/0960327108088978
    • (2008) Hum Exp Toxicol , vol.27 , pp. 55-63
    • Prasad, S.1    Kalra, N.2    Srivastava, S.3    Shukla, Y.4
  • 111
    • 33745600868 scopus 로고    scopus 로고
    • Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective
    • 10.1016/j.jconrel.2006.04.015
    • DV Ratnam DD Ankola V Bhardwaj DK Sahana MN Kumar 2006 Role of antioxidants in prophylaxis and therapy: a pharmaceutical perspective J Control Release 113 189 207 10.1016/j.jconrel.2006.04.015
    • (2006) J Control Release , vol.113 , pp. 189-207
    • Ratnam, D.V.1    Ankola, D.D.2    Bhardwaj, V.3    Sahana, D.K.4    Kumar, M.N.5
  • 112
    • 0034903749 scopus 로고    scopus 로고
    • Effects of the garlic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cells: Evidence of sensitive and resistant sub-populations
    • V Robert B Mouille C Mayeur M Michaud F Blachier 2001 Effects of the garlic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cells: evidence of sensitive and resistant sub-populations Carcinogenesis 22 1155 1161 10.1093/carcin/22.8.1155 (Pubitemid 32737329)
    • (2001) Carcinogenesis , vol.22 , Issue.8 , pp. 1155-1161
    • Robert, V.1    Mouille, B.2    Mayeur, C.3    Michaud, M.4    Blachier, F.5
  • 113
    • 34447284774 scopus 로고    scopus 로고
    • Allium sativum constituents: Effect on free radical generation from rat neutrophils
    • DOI 10.1170/T819
    • A Sankaranarayanan T Narender S Kumar M Dikshit 2007 Allium sativum constituents: effect on free radical generation from rat neutrophils Cell Mol Biol (Noisy-le-grand) 53 63 67 (Pubitemid 350164306)
    • (2007) Cellular and Molecular Biology , vol.53 , Issue.5 , pp. 63-67
    • Sankaranarayanan, A.1    Narender, T.2    Kumar, S.3    Dikshit, M.4
  • 114
    • 0034634761 scopus 로고    scopus 로고
    • Garlic and onion oils inhibit proliferation and induce differentiation of HL-60 cells
    • 10.1016/S0304-3835(00)00552-8
    • T Seki K Tsuji Y Hayato T Moritomo T Ariga 2000 Garlic and onion oils inhibit proliferation and induce differentiation of HL-60 cells Cancer Lett 160 29 35 10.1016/S0304-3835(00)00552-8
    • (2000) Cancer Lett , vol.160 , pp. 29-35
    • Seki, T.1    Tsuji, K.2    Hayato, Y.3    Moritomo, T.4    Ariga, T.5
  • 115
    • 0032961434 scopus 로고    scopus 로고
    • Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration
    • 10.1016/S0005-2728(99)00011-0
    • J Serrano CM Palmeira DW Kuehl KB Wallace 1999 Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration Biochim Biophys Acta 1411 201 205 10.1016/S0005-2728(99)00011-0
    • (1999) Biochim Biophys Acta , vol.1411 , pp. 201-205
    • Serrano, J.1    Palmeira, C.M.2    Kuehl, D.W.3    Wallace, K.B.4
  • 117
    • 0035964441 scopus 로고    scopus 로고
    • Carbon tetrachloride-induced changes in the activity of phase II drug-metabolizing enzyme in the liver of male rats: Role of antioxidants
    • 10.1016/S0300-483X(01)00429-2
    • SA Sheweita M Abd El-Gabar M Bastawy 2001 Carbon tetrachloride-induced changes in the activity of phase II drug-metabolizing enzyme in the liver of male rats: role of antioxidants Toxicology 165 217 224 10.1016/S0300-483X(01) 00429-2
    • (2001) Toxicology , vol.165 , pp. 217-224
    • Sheweita, S.A.1    Abd El-Gabar, M.2    Bastawy, M.3
  • 118
    • 33846931878 scopus 로고    scopus 로고
    • Cancer chemoprevention with garlic and its constituents
    • 10.1016/j.canlet.2006.05.009
    • Y Shukla N Kalra 2007 Cancer chemoprevention with garlic and its constituents Cancer Lett 247 167 181 10.1016/j.canlet.2006.05.009
    • (2007) Cancer Lett , vol.247 , pp. 167-181
    • Shukla, Y.1    Kalra, N.2
  • 119
    • 0033093866 scopus 로고    scopus 로고
    • Effects of garlic preparations on superoxide production by phorbol ester activated granulocytes
    • CP Siegers A Robke R Pentz 1999 Effects of garlic preparations on superoxide production by phorbol ester activated granulocytes Phytomedicine 6 13 16 (Pubitemid 129632488)
    • (1999) Phytomedicine , vol.6 , Issue.1 , pp. 13-16
    • Siegers, C.-P.1    Robke, A.2    Pentz, R.3
  • 120
    • 0002549698 scopus 로고
    • Oxidative stress: Introductory remarks
    • Academic Press New York
    • Sies H (1985) Oxidative stress: introductory remarks. In: Sies H (ed) Oxidative stress. Academic Press, pp 1-8
    • (1985) Oxidative Stress , pp. 1-8
    • Sies, H.1    Sies, H.2
  • 121
    • 0031057489 scopus 로고    scopus 로고
    • S-allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines
    • G Sigounas J Hooker A Anagnostou M Steiner 1997 S-allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines Nutr Cancer 27 186 191 (Pubitemid 27089694)
    • (1997) Nutrition and Cancer , vol.27 , Issue.2 , pp. 186-191
    • Sigounas, G.1    Hooker, J.2    Anagnostou, A.3    Steiner, M.4
  • 122
    • 0030826223 scopus 로고    scopus 로고
    • S-allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines
    • G Sigounas JL Hooker W Li A Anagnostou M Steiner 1997 S-allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines Nutr Cancer 28 153 159 (Pubitemid 27396203)
    • (1997) Nutrition and Cancer , vol.28 , Issue.2 , pp. 153-159
    • Sigounas, G.1    Hooker, J.L.2    Li, W.3    Anagnostou, A.4    Steiner, M.5
  • 123
    • 0035125669 scopus 로고    scopus 로고
    • Impact of garlic organosulfides on p21(H-ras) processing
    • SV Singh 2001 Impact of garlic organosulfides on p21(H-ras) processing J Nutr 131 1046S 1048S
    • (2001) J Nutr , vol.131
    • Singh, S.V.1
  • 124
    • 0030583242 scopus 로고    scopus 로고
    • Novel anti-carcinogenic activity of an organosulfide from garlic: Inhibition of H-RAS oncogene transformed tumor growth in vivo by diallyl disulfide is associated with inhibition of p21H-ras processing
    • 10.1006/bbrc.1996.1226
    • SV Singh RR Mohan R Agarwal 1996 Novel anti-carcinogenic activity of an organosulfide from garlic: inhibition of H-RAS oncogene transformed tumor growth in vivo by diallyl disulfide is associated with inhibition of p21H-ras processing Biochem Biophys Res Commun 225 660 665 10.1006/bbrc.1996.1226
    • (1996) Biochem Biophys Res Commun , vol.225 , pp. 660-665
    • Singh, S.V.1    Mohan, R.R.2    Agarwal, R.3
  • 125
    • 33749655260 scopus 로고    scopus 로고
    • Inhibition of ICAM-1 expression by garlic component, allicin, in gamma-irradiated human vascular endothelial cells via downregulation of the JNK signaling pathway
    • 10.1016/j.intimp.2006.07.021
    • EW Son SJ Mo DK Rhee S Pyo 2006 Inhibition of ICAM-1 expression by garlic component, allicin, in gamma-irradiated human vascular endothelial cells via downregulation of the JNK signaling pathway Int Immunopharmacol 6 1788 1795 10.1016/j.intimp.2006.07.021
    • (2006) Int Immunopharmacol , vol.6 , pp. 1788-1795
    • Son, E.W.1    Mo, S.J.2    Rhee, D.K.3    Pyo, S.4
  • 126
    • 41349115251 scopus 로고    scopus 로고
    • Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: Involvement of caspase-3, NF-kappaB, and ERK-2
    • 10.1007/s11010-008-9706-8
    • N Sriram S Kalayarasan P Ashokkumar A Sureshkumar G Sudhandiran 2008 Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-kappaB, and ERK-2 Mol Cell Biochem 311 157 165 10.1007/s11010-008-9706-8
    • (2008) Mol Cell Biochem , vol.311 , pp. 157-165
    • Sriram, N.1    Kalayarasan, S.2    Ashokkumar, P.3    Sureshkumar, A.4    Sudhandiran, G.5
  • 128
    • 39949085057 scopus 로고    scopus 로고
    • Prevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by S-allylcysteine
    • 10.1007/s11010-007-9682-4
    • S Sundaresan P Subramanian 2008 Prevention of N-nitrosodiethylamine- induced hepatocarcinogenesis by S-allylcysteine Mol Cell Biochem 310 209 214 10.1007/s11010-007-9682-4
    • (2008) Mol Cell Biochem , vol.310 , pp. 209-214
    • Sundaresan, S.1    Subramanian, P.2
  • 129
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • TP Szatrowski CF Nathan 1991 Production of large amounts of hydrogen peroxide by human tumor cells Cancer Res 51 794 798
    • (1991) Cancer Res , vol.51 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 132
    • 1842785712 scopus 로고    scopus 로고
    • Organosulfur compounds from Alliaceae in the prevention of human pathologies
    • 10.1016/j.biopha.2004.01.004
    • H Tapiero DM Townsend KD Tew 2004 Organosulfur compounds from Alliaceae in the prevention of human pathologies Biomed Pharmacother 58 183 193 10.1016/j.biopha.2004.01.004
    • (2004) Biomed Pharmacother , vol.58 , pp. 183-193
    • Tapiero, H.1    Townsend, D.M.2    Tew, K.D.3
  • 133
    • 0036900284 scopus 로고    scopus 로고
    • Diallyl disulfide increases rat H-ferritin, L-ferritin and transferrin receptor genes in vitro in hepatic cells and in vivo in liver
    • M Thomas P Zhang ML Noordine P Vaugelade C Chaumontet PH Duee 2002 Diallyl disulfide increases rat H-ferritin, L-ferritin and transferrin receptor genes in vitro in hepatic cells and in vivo in liver J Nutr 132 3638 3641 (Pubitemid 35435040)
    • (2002) Journal of Nutrition , vol.132 , Issue.12 , pp. 3638-3641
    • Thomas, M.1    Zhang, P.2    Noordine, M.-L.3    Vaugelade, P.4    Chaumontet, C.5    Duee, P.-H.6
  • 134
    • 0042659566 scopus 로고    scopus 로고
    • The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis
    • 10.1007/s00403-003-0404-9
    • CM Tilli AJ Stavast-Kooy JD Vuerstaek 2003 The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis Arch Dermatol Res 295 117 123 10.1007/s00403-003-0404-9
    • (2003) Arch Dermatol Res , vol.295 , pp. 117-123
    • Tilli, C.M.1    Stavast-Kooy, A.J.2    Vuerstaek, J.D.3
  • 135
    • 34247855058 scopus 로고    scopus 로고
    • Diallyl disulfide and diallyl trisulfide up-regulate the expression of the pi class of glutathione S-transferase via an AP-1-dependent pathway
    • 10.1021/jf061874t
    • CW Tsai HW Chen JJ Yang LY Sheen CK Lii 2007 Diallyl disulfide and diallyl trisulfide up-regulate the expression of the pi class of glutathione S-transferase via an AP-1-dependent pathway J Agric Food Chem 55 1019 1026 10.1021/jf061874t
    • (2007) J Agric Food Chem , vol.55 , pp. 1019-1026
    • Tsai, C.W.1    Chen, H.W.2    Yang, J.J.3    Sheen, L.Y.4    Lii, C.K.5
  • 136
    • 44449125132 scopus 로고    scopus 로고
    • Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy
    • 10.1016/j.canlet.2008.02.044
    • M Ushio-Fukai Y Nakamura 2008 Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy Cancer Lett 266 37 52 10.1016/j.canlet.2008.02.044
    • (2008) Cancer Lett , vol.266 , pp. 37-52
    • Ushio-Fukai, M.1    Nakamura, Y.2
  • 137
    • 2942547684 scopus 로고    scopus 로고
    • Enhancement of diallyl disulfide-induced apoptosis by inhibitors of MAPKs in human HepG2 hepatoma cells
    • 10.1016/j.bcp.2004.03.027
    • J Wen Y Zhang X Chen L Shen GC Li M Xu 2004 Enhancement of diallyl disulfide-induced apoptosis by inhibitors of MAPKs in human HepG2 hepatoma cells Biochem Pharmacol 68 323 331 10.1016/j.bcp.2004.03.027
    • (2004) Biochem Pharmacol , vol.68 , pp. 323-331
    • Wen, J.1    Zhang, Y.2    Chen, X.3    Shen, L.4    Li, G.C.5    Xu, M.6
  • 138
    • 0028904871 scopus 로고
    • Transient adaptation of oxidative stress in mammalian cells
    • 10.1006/abbi.1995.1225
    • AG Wiese RE Pacifici KJ Davies 1995 Transient adaptation of oxidative stress in mammalian cells Arch Biochem Biophys 318 231 240 10.1006/abbi.1995. 1225
    • (1995) Arch Biochem Biophys , vol.318 , pp. 231-240
    • Wiese, A.G.1    Pacifici, R.E.2    Davies, K.J.3
  • 139
    • 22744441812 scopus 로고    scopus 로고
    • Oxidative activation of antioxidant defence
    • 10.1016/j.tibs.2005.06.001
    • PG Winyard CJ Moody C Jacob 2005 Oxidative activation of antioxidant defence Trends Biochem Sci 30 453 461 10.1016/j.tibs.2005.06.001
    • (2005) Trends Biochem Sci , vol.30 , pp. 453-461
    • Winyard, P.G.1    Moody, C.J.2    Jacob, C.3
  • 140
    • 0037116438 scopus 로고    scopus 로고
    • Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats
    • 10.1021/jf010937z
    • CC Wu LY Sheen HW Chen WW Kuo SJ Tsai CK Lii 2002 Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats J Agric Food Chem 50 378 383 10.1021/jf010937z
    • (2002) J Agric Food Chem , vol.50 , pp. 378-383
    • Wu, C.C.1    Sheen, L.Y.2    Chen, H.W.3    Kuo, W.W.4    Tsai, S.J.5    Lii, C.K.6
  • 141
    • 7044263002 scopus 로고    scopus 로고
    • Differential effects of allyl sulfides from garlic essential oil on cell cycle regulation in human liver tumor cells
    • 10.1016/j.fct.2004.07.008
    • CC Wu JG Chung SJ Tsai JH Yang LY Sheen 2004 Differential effects of allyl sulfides from garlic essential oil on cell cycle regulation in human liver tumor cells Food Chem Toxicol 42 1937 1947 10.1016/j.fct.2004.07.008
    • (2004) Food Chem Toxicol , vol.42 , pp. 1937-1947
    • Wu, C.C.1    Chung, J.G.2    Tsai, S.J.3    Yang, J.H.4    Sheen, L.Y.5
  • 142
    • 15944377864 scopus 로고    scopus 로고
    • Induction of apoptosis in tumor cells by naturally occurring sulfur-containing compounds
    • 10.1016/j.mrrev.2004.11.001
    • X Wu F Kassie V Mersch-Sundermann 2005 Induction of apoptosis in tumor cells by naturally occurring sulfur-containing compounds Mutat Res 589 81 102 10.1016/j.mrrev.2004.11.001
    • (2005) Mutat Res , vol.589 , pp. 81-102
    • Wu, X.1    Kassie, F.2    Mersch-Sundermann, V.3
  • 143
    • 33644869135 scopus 로고    scopus 로고
    • Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells
    • 10.1093/carcin/bgi228
    • D Xiao SV Singh 2006 Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells Carcinogenesis 27 533 540 10.1093/carcin/bgi228
    • (2006) Carcinogenesis , vol.27 , pp. 533-540
    • Xiao, D.1    Singh, S.V.2
  • 145
    • 3342895063 scopus 로고    scopus 로고
    • Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2
    • 10.1038/sj.onc.1207747
    • D Xiao S Choi DE Johnson 2004 Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2 Oncogene 23 5594 5606 10.1038/sj.onc.1207747
    • (2004) Oncogene , vol.23 , pp. 5594-5606
    • Xiao, D.1    Choi, S.2    Johnson, D.E.3
  • 146
    • 33644666598 scopus 로고    scopus 로고
    • Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells
    • 10.1158/1535-7163.MCT-05-0152
    • D Xiao JT Pinto GG Gundersen IB Weinstein 2005 Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells Mol Cancer Ther 4 1388 1398 10.1158/1535-7163.MCT-05-0152
    • (2005) Mol Cancer Ther , vol.4 , pp. 1388-1398
    • Xiao, D.1    Pinto, J.T.2    Gundersen, G.G.3    Weinstein, I.B.4
  • 147
    • 28044435379 scopus 로고    scopus 로고
    • Diallyl trisulfide-induced G(2)-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc 25 C
    • 10.1038/sj.onc.1208759
    • D Xiao A Herman-Antosiewicz J Antosiewicz 2005 Diallyl trisulfide-induced G(2)-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc 25 C Oncogene 24 6256 6268 10.1038/sj.onc.1208759
    • (2005) Oncogene , vol.24 , pp. 6256-6268
    • Xiao, D.1    Herman-Antosiewicz, A.2    Antosiewicz, J.3
  • 148
    • 33749183133 scopus 로고    scopus 로고
    • Diallyl trisulfide inhibits angiogenic features of human umbilical vein endothelial cells by causing Akt inactivation and down-regulation of VEGF and VEGF-R2
    • 10.1207/s15327914nc5501-12
    • D Xiao M Li A Herman-Antosiewicz 2006 Diallyl trisulfide inhibits angiogenic features of human umbilical vein endothelial cells by causing Akt inactivation and down-regulation of VEGF and VEGF-R2 Nutr Cancer 55 94 107 10.1207/s15327914nc5501-12
    • (2006) Nutr Cancer , vol.55 , pp. 94-107
    • Xiao, D.1    Li, M.2    Herman-Antosiewicz, A.3
  • 149
    • 0035126521 scopus 로고    scopus 로고
    • Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic
    • CS Yang SK Chhabra JY Hong TJ Smith 2001 Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic J Nutr 131 1041S 1045S (Pubitemid 32195003)
    • (2001) Journal of Nutrition , vol.131 , Issue.SUPPL.
    • Yang, C.S.1    Chhabra, S.K.2    Hong, J.-Y.3    Smith, T.J.4


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