Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells

Carcinogenesis

Volumn 27, Issue 3, 2006, Pages 533-540

  Xiao, Dong ^a   Singh, Shivendra V ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; DIALLYL TRISULFIDE; GARLIC EXTRACT; PROTEIN 14 3 3; PROTEIN BAD; PROTEIN KINASE B; SERINE; SOMATOMEDIN C RECEPTOR; THREONINE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHOSPHORYLATION; CANCER CELL CULTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MITOCHONDRION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE;

ALLYL COMPOUNDS; ANTIOXIDANTS; APOPTOSIS; CASPASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GARLIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRIA; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SULFIDES; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 33644869135     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi228     Document Type: Article

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