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Volumn 48, Issue 2, 2005, Pages 95-100

An overview of the antifungal properties of allicin and its breakdown products - The possibility of a safe and effective antifungal prophylactic

Author keywords

Allicin; Allitridium; Antifungal; Garlic

Indexed keywords

ALLICIN; AMINO ACID; AMPHOTERICIN B; DIALLYL TRISULFIDE; GARLIC EXTRACT; GLUTATHIONE; PROTEIN; SULFUR;

EID: 15444378850     PISSN: 09337407     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1439-0507.2004.01076.x     Document Type: Review
Times cited : (89)

References (40)
  • 1
    • 0029801915 scopus 로고    scopus 로고
    • Enhanced diallyl trisulfide has in vitro synergy with amphotericin B against Cryptococcus neoformans
    • Shen JK, Davis LE, Wallace JM, Cai Y, Lawson LD. Enhanced diallyl trisulfide has in vitro synergy with amphotericin B against Cryptococcus neoformans. Planta Medica 1996; 62: 415-8.
    • (1996) Planta Medica , vol.62 , pp. 415-418
    • Shen, J.K.1    Davis, L.E.2    Wallace, J.M.3    Cai, Y.4    Lawson, L.D.5
  • 2
    • 0025327152 scopus 로고
    • Antifungal activity in human cerebrospinal fluid and plasma after intravenous administration of Allium sativum Antimicrob
    • Davis LE, Shen JK, Cai Y. Antifungal activity in human cerebrospinal fluid and plasma after intravenous administration of Allium sativum Antimicrob. Agents Chemother 1990; 4: 651-3.
    • (1990) Agents Chemother , vol.4 , pp. 651-653
    • Davis, L.E.1    Shen, J.K.2    Cai, Y.3
  • 3
    • 0037340430 scopus 로고    scopus 로고
    • The in-vitro susceptibility of Scedosporium prolificans to ajoene, allitridium, and a raw extract of garlic (Allium sativum)
    • Davis SR, Perrie R. The in-vitro susceptibility of Scedosporium prolificans to ajoene, allitridium, and a raw extract of garlic (Allium sativum). J Antimicrob Chemother 2003; 51: 593-7.
    • (2003) J Antimicrob Chemother , vol.51 , pp. 593-597
    • Davis, S.R.1    Perrie, R.2
  • 4
    • 15444371029 scopus 로고    scopus 로고
    • The in-vitro susceptibility of Cryptococcus neoformans to allitridium
    • San Antonio, TX, USA, May 25-29, (abstract 113)
    • Davis SR, Perrie R, The in-vitro susceptibility of Cryptococcus neoformans to allitridium. In: Program and Abstracts of the 15th Congress of ISHAM. San Antonio, TX, USA, May 25-29, 2003 (abstract 113).
    • (2003) Program and Abstracts of the 15th Congress of ISHAM
    • Davis, S.R.1    Perrie, R.2
  • 5
    • 15444363159 scopus 로고    scopus 로고
    • Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in-vitro and in a murine model of disseminated aspergillosis
    • Chicago, IL, USA. September 14-17, [abstract 99(M)]
    • Osherov N, Shemesh E, Mirelman D et al. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in-vitro and in a murine model of disseminated aspergillosis. In: 43rd ICAAC Abstracts. Chicago, IL, USA. September 14-17, 2003 [abstract 99(M)].
    • (2003) 43rd ICAAC Abstracts
    • Osherov, N.1    Shemesh, E.2    Mirelman, D.3
  • 6
    • 0022039421 scopus 로고
    • The chemistry of garlic and onions
    • Block E. The chemistry of garlic and onions. Sci Am 1985; 252: 114-9.
    • (1985) Sci Am , vol.252 , pp. 114-119
    • Block, E.1
  • 7
    • 0028948426 scopus 로고
    • Antifungal effects of Allium sativum (garlic) extract against the Aspergillus species involved in otomycosis
    • Pai ST, Platt MW. Antifungal effects of Allium sativum (garlic) extract against the Aspergillus species involved in otomycosis. Lett Appl Microbiol 1995; 20: 14-8.
    • (1995) Lett Appl Microbiol , vol.20 , pp. 14-18
    • Pai, S.T.1    Platt, M.W.2
  • 9
    • 0002466403 scopus 로고
    • Antimicrobial properties of spices and their essential oils
    • Dillon VM, Board RG (eds), Oxon, UK: Cab international
    • Beuchat LR. Antimicrobial properties of spices and their essential oils. In: Dillon VM, Board RG (eds), Natural Antimicrobial Systems and Food Preservation. Oxon, UK: Cab international, 1994: 99-131.
    • (1994) Natural Antimicrobial Systems and Food Preservation , pp. 99-131
    • Beuchat, L.R.1
  • 10
    • 0033744198 scopus 로고    scopus 로고
    • Efficacy of ajoene in the treatment of tinea pedis: A double blind and comparative study with terbinafine
    • Ledezma E, Marcano K, Jorquera A et al. Efficacy of ajoene in the treatment of tinea pedis: a double blind and comparative study with terbinafine. J Am Acad Dermatol 2000; 43: 829-32.
    • (2000) J Am Acad Dermatol , vol.43 , pp. 829-832
    • Ledezma, E.1    Marcano, K.2    Jorquera, A.3
  • 11
    • 0346786772 scopus 로고    scopus 로고
    • Garlic: A review of its medicinal effects and indicated active compounds
    • Lawson LD, Bauer R (eds), Washington, DC, USA: American Chemical Society
    • Lawson LD. Garlic: a review of its medicinal effects and indicated active compounds. In: Lawson LD, Bauer R (eds), Phytomedicines of Europe: Chemistry and Biological Activity, ACS Symposium Series no. 691. Washington, DC, USA: American Chemical Society. 1998: 176-209.
    • (1998) Phytomedicines of Europe: Chemistry and Biological Activity, ACS Symposium Series No. 691 , pp. 176-209
    • Lawson, L.D.1
  • 12
    • 0027950628 scopus 로고
    • Alliin lyase localization in bundle sheaths of garlic clove (Allium sativum)
    • Ellmore G, Feldberg R. Alliin lyase localization in bundle sheaths of garlic clove (Allium sativum). Am J Bot 1994; 81: 89-95.
    • (1994) Am J Bot , vol.81 , pp. 89-95
    • Ellmore, G.1    Feldberg, R.2
  • 13
    • 0000817158 scopus 로고
    • Garlic chemistry: Stability of S-(2-propenyl)-2-propene-1-sulfinothionate (allicin) in blood, solvents, and simulated physiological fluids
    • Freeman F, Kodera Y. Garlic chemistry: stability of S-(2-propenyl)-2- propene-1-sulfinothionate (allicin) in blood, solvents, and simulated physiological fluids. J Agric Food Chem 1995; 43: 2332-8.
    • (1995) J Agric Food Chem , vol.43 , pp. 2332-2338
    • Freeman, F.1    Kodera, Y.2
  • 14
    • 0033064615 scopus 로고    scopus 로고
    • Metabolism of diallyl disulfide by human liver microsomal cytochromes P 450 and flavin-containing monooxygenases
    • Teyssier C, Guenot L, Suschetet M, Siess MH. Metabolism of diallyl disulfide by human liver microsomal cytochromes P 450 and flavin-containing monooxygenases. Drug Metab Dispos 1999; 27: 835-41.
    • (1999) Drug Metab Dispos , vol.27 , pp. 835-841
    • Teyssier, C.1    Guenot, L.2    Suschetet, M.3    Siess, M.H.4
  • 15
    • 0032715514 scopus 로고    scopus 로고
    • Antimicrobial properties of allicin from garlic
    • Ankri S, Mirelman D. Antimicrobial properties of allicin from garlic. Microbes Infect 1999; 2: 125-9.
    • (1999) Microbes Infect , vol.2 , pp. 125-129
    • Ankri, S.1    Mirelman, D.2
  • 16
    • 0031445546 scopus 로고    scopus 로고
    • Allyl sulfides from garlic suppress the in vitro proliferation of human A549 lung tumor cells
    • Sakamoto K, Lawson LD, Milner JA. Allyl sulfides from garlic suppress the in vitro proliferation of human A549 lung tumor cells. Nutr Cancer 1997; 29: 152-6.
    • (1997) Nutr Cancer , vol.29 , pp. 152-156
    • Sakamoto, K.1    Lawson, L.D.2    Milner, J.A.3
  • 17
    • 0034687099 scopus 로고    scopus 로고
    • Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trials
    • Stevinson C, Pittler MH, Ernst E. Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trials. Ann Intern Med 2000; 133: 420-9.
    • (2000) Ann Intern Med , vol.133 , pp. 420-429
    • Stevinson, C.1    Pittler, M.H.2    Ernst, E.3
  • 18
    • 0035172897 scopus 로고    scopus 로고
    • Antimicrobial properties of garlic oil against human enteric bacteria: Evaluation of methodologies and comparisons with garlic oil sulfides and garlic powder
    • Ross ZM, O'Gara EA, Hill DJ, Sleightholme HV, Maslin DJ. Antimicrobial properties of garlic oil against human enteric bacteria: evaluation of methodologies and comparisons with garlic oil sulfides and garlic powder. Appl Environ Microbiol 2001; 67: 475-80.
    • (2001) Appl Environ Microbiol , vol.67 , pp. 475-480
    • Ross, Z.M.1    O'Gara, E.A.2    Hill, D.J.3    Sleightholme, H.V.4    Maslin, D.J.5
  • 20
    • 0034948918 scopus 로고    scopus 로고
    • In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils
    • Tsao SM, Yin MC. In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils. J Med Microbiol 2001; 50: 646-9.
    • (2001) J Med Microbiol , vol.50 , pp. 646-649
    • Tsao, S.M.1    Yin, M.C.2
  • 21
    • 0033973286 scopus 로고    scopus 로고
    • The mode of action of allicin: Its ready permeability through phospholipid membranes may contribute to its biological activity
    • Miron T, Rabinkov A, Mirelman D, Wilchek M, Weiner L. The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity. Biochim Biophys Acta 2000; 1463: 20-30.
    • (2000) Biochim Biophys Acta , vol.1463 , pp. 20-30
    • Miron, T.1    Rabinkov, A.2    Mirelman, D.3    Wilchek, M.4    Weiner, L.5
  • 22
    • 0001502075 scopus 로고
    • Tumor inhibition by a sulphydryl-blocking agent related to an active principle of garlic (Allium sativum)
    • Weisberger AS, Pensky J. Tumor inhibition by a sulphydryl-blocking agent related to an active principle of garlic (Allium sativum). Cancer Res 1958; 18: 1301-6.
    • (1958) Cancer Res , vol.18 , pp. 1301-1306
    • Weisberger, A.S.1    Pensky, J.2
  • 23
    • 4344625883 scopus 로고    scopus 로고
    • A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells
    • Friesen C, Kiess Y, Debatin KM. A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells. Cell Death Differ 2004; 11(Suppl. 1): S73-85.
    • (2004) Cell Death Differ , vol.11 , Issue.SUPPL. 1
    • Friesen, C.1    Kiess, Y.2    Debatin, K.M.3
  • 24
    • 0034639280 scopus 로고    scopus 로고
    • Allylmercaptoglutathione: The reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties
    • Rabinkov A, Miron T, Mirelman D et al. Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties. Biochim Biophys Acta 2000; 1499: 144-53.
    • (2000) Biochim Biophys Acta , vol.1499 , pp. 144-153
    • Rabinkov, A.1    Miron, T.2    Mirelman, D.3
  • 25
    • 0022539320 scopus 로고
    • Allium sativum (garlic) inhibits lipid synthesis by Candida albicans
    • Adetumbi M, Javor GT, Lau BH. Allium sativum (garlic) inhibits lipid synthesis by Candida albicans. Antimicrob Agents Chemother 1986; 30: 499-501.
    • (1986) Antimicrob Agents Chemother , vol.30 , pp. 499-501
    • Adetumbi, M.1    Javor, G.T.2    Lau, B.H.3
  • 26
    • 0034989513 scopus 로고    scopus 로고
    • Garlic and garlic-derived compounds inhibit human squalene monooxygenase
    • Gupta N, Porter TD. Garlic and garlic-derived compounds inhibit human squalene monooxygenase. J Nutr 2001; 131: 1662-7.
    • (2001) J Nutr , vol.131 , pp. 1662-1667
    • Gupta, N.1    Porter, T.D.2
  • 29
    • 0035126669 scopus 로고    scopus 로고
    • Enhanced immunocompetence by garlic: Role in bladder cancer and other malignancies
    • Lamm DL, Riggs DR. Enhanced immunocompetence by garlic: role in bladder cancer and other malignancies. J Nutr 2001; 131: 1067S-70S.
    • (2001) J Nutr , vol.131
    • Lamm, D.L.1    Riggs, D.R.2
  • 30
    • 0019126725 scopus 로고
    • Effect of garlic on serum lipids and lipoproteins in patients suffering from hyperlipoproteinemia
    • Sucur M. Effect of garlic on serum lipids and lipoproteins in patients suffering from hyperlipoproteinemia. Diabetol Croat 1980; 9: 323-38.
    • (1980) Diabetol Croat , vol.9 , pp. 323-338
    • Sucur, M.1
  • 31
    • 0026184926 scopus 로고
    • Effect of ingestion of raw garlic on serum cholesterol level, clotting time and fibrinolytic activity in normal subjects
    • Gadkari JV, Joshi VD. Effect of ingestion of raw garlic on serum cholesterol level, clotting time and fibrinolytic activity in normal subjects. J Postgrad Med 1991; 37: 128-31.
    • (1991) J Postgrad Med , vol.37 , pp. 128-131
    • Gadkari, J.V.1    Joshi, V.D.2
  • 32
    • 0025312180 scopus 로고
    • Spontaneous spinal epidural hematoma with associated platelet dysfunction from excessive garlic ingestion: A case report
    • Rose KD, Croissant PD, Parliament CF, Levin MB. Spontaneous spinal epidural hematoma with associated platelet dysfunction from excessive garlic ingestion: a case report. Neurosurgery 1990; 26: 880-2.
    • (1990) Neurosurgery , vol.26 , pp. 880-882
    • Rose, K.D.1    Croissant, P.D.2    Parliament, C.F.3    Levin, M.B.4
  • 33
    • 0001048658 scopus 로고
    • Warfarin and garlic
    • Sunter W. Warfarin and garlic. Pharm J 1991; 246: 72.
    • (1991) Pharm J , vol.246 , pp. 72
    • Sunter, W.1
  • 35
    • 0033067816 scopus 로고    scopus 로고
    • Garlic-related dermatoses: Case report and review of the literature
    • Jappe U, Bonnekoh B, Hausen BM, Gollnick H. Garlic-related dermatoses: case report and review of the literature. Am J Contact Dermat 1999; 10: 37-9.
    • (1999) Am J Contact Dermat , vol.10 , pp. 37-39
    • Jappe, U.1    Bonnekoh, B.2    Hausen, B.M.3    Gollnick, H.4
  • 37
    • 0033757929 scopus 로고    scopus 로고
    • Hematologic changes associated with the appearance of eccentrocytes after intragastric administration of garlic extract to dogs
    • Lee KW, Yamato O, Tajima M, Kuraoka M, Omae S, Maede Y. Hematologic changes associated with the appearance of eccentrocytes after intragastric administration of garlic extract to dogs. Am J Vet Res 2000; 61: 1446-50.
    • (2000) Am J Vet Res , vol.61 , pp. 1446-1450
    • Lee, K.W.1    Yamato, O.2    Tajima, M.3    Kuraoka, M.4    Omae, S.5    Maede, Y.6
  • 38
    • 0035026083 scopus 로고    scopus 로고
    • Alternative medicine: Herbal drugs and their critical appraisal
    • Kaul PN, Joshi BS. Alternative medicine: herbal drugs and their critical appraisal. Prog Drug Res 2001; 57: 1-75.
    • (2001) Prog Drug Res , vol.57 , pp. 1-75
    • Kaul, P.N.1    Joshi, B.S.2
  • 39
    • 33947445717 scopus 로고
    • Allicin, the antibacterial principle of Allium sativum. 1. Isolation, physical properties, and antibacterial action
    • Cavallito CJ, Bailey JH, Buck J. Allicin, the antibacterial principle of Allium sativum. 1. Isolation, physical properties, and antibacterial action. J Am Chem Soc 1944; 66: 1950.
    • (1944) J Am Chem Soc , vol.66 , pp. 1950
    • Cavallito, C.J.1    Bailey, J.H.2    Buck, J.3
  • 40
    • 0003089632 scopus 로고    scopus 로고
    • The composition and chemistry of garlic cloves and processed garlic
    • Koch HP, Lawson LD (eds), Baltimore, MD, USA: Williams & Wilkins
    • Lawson LD. The composition and chemistry of garlic cloves and processed garlic. In: Koch HP, Lawson LD (eds), Garlic: The Science and Therapeutic Application of Allium sativum L. and Related Species. Baltimore, MD, USA: Williams & Wilkins, 1996: 37-107.
    • (1996) Garlic: The Science and Therapeutic Application of Allium Sativum L. and Related Species , pp. 37-107
    • Lawson, L.D.1


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