Ajoene-induced cell death in human promyeloleukemic cells does not require JNK but is amplified by the inhibition of ERK

Oncogene

Volumn 22, Issue 4, 2003, Pages 582-589

  Antlsperger, Dorothee S M ^a   Dirsch, Verena M ^a,c   Ferreira, Dulce ^a   Su, Jen Liang ^b   Kuo, Ming Liang ^b   Vollmar, Angelika M ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c Center of Drug Research   (Germany)

Author keywords

Ajoene; Apoptosis; C Jun NH2 terminal kinase; Extracellular signal regulated kinases; Mitogen activated protein kinase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AJOENE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; ETOPOSIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WORTMANNIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

APOPTOSIS; BLOTTING, WESTERN; DISULFIDES; ENZYME ACTIVATION; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEUKEMIA, PROMYELOCYTIC, ACUTE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS;

EID: 0037473080     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206161     Document Type: Article

References (44)

1. Agarwal KC. (1996). Med. Res. Rev., 16, 111-124.
2. Bamford M, Walkinshaw G and Brown R. (2000). Exp. Cell Res., 256, 1-11.
3. Bennett BB, Sasaki DT, Brion WM, Eoin COL, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y, Bhagwat SS, Manning AM and Anderson DW. (2001). Proc. Natl. Acad. Sci. USA, 98, 13681-13686.
4. Bradford MM. (1976). Anal. Biochem., 72, 248-254.
5. Butterfield L, Storey B, Maas L and Heasley LE. (1997). J. Biol. Chem., 272, 10110-10116.
6. Chang L and Karin M. (2001). Nature, 410, 37-40.
7. Chen YR, Wang W, Kong AN and Tan TH. (1998). J. Biol. Chem., 273, 1769-1775.
8. Chen YR, Wang X, Templeton D, Davis RJ and Tan TH. (1996). J. Biol. Chem., 271, 31929-31936.
9. Chen YR, Zhou G and Tan TH. (1999). Mol. Pharmacol., 56, 1271-1279.
10. Datta SR, Brunet A and Greenberg ME. (1999). Genes Dev., 13, 2905-2927.
11. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y and Greenberg ME. (1997). Cell, 91, 231-241.
12. del Peso L, Gonzalez-Garcia M, Page C, Herrera R and Nunez G. (1997). Science, 278, 687-689.
13. Dirsch VM, Antlsperger DSM, Hentze H and Vollmar AM. (2002). Leukemia, 16, 74-83.
14. Dirsch VM, Gerbes AL and Vollmar AM. (1998). Mol. Pharmacol., 53, 402-407.
15. Dirsch VM, Stuppner H and Vollmar AM. (2001). Cancer Res., 61, 5817-5823.
16. Eichhorst ST, Muller M, Li-Weber M, Schulze-Bergkamen H, Angel P and Krammer PH. (2000). Mol. Cell Biol., 20, 7826-7837.
17. Eilers A, Whitfield J, Shah B, Spadoni C, Desmond H and Ham J. (2001). J. Neurochem., 76, 1439-1454.
18. Galan A, Garcia-Bermejo ML, Troyano A, Vilaboa NE, de Blas E, Kazanietz MG and Aller P. (2000). J. Biol. Chem., 275, 11418-11424.
19. Gupta K, Kshirsagar S, Li W, Gui L, Ramakrishnan S, Gupta P, Law PY and Hebbel RP. (1999). Exp. Cell Res., 247, 495-504.
20. Hancock JT, Desikan R and Neill SJ. (2001). Biochem. Soc. Trans., 29, 345-350.
21. Herr I and Debatin KM. (2001). Blood, 98, 2603-2614.
22. Ibrado AM, Huang Y, Fang G, Liu L and Bhalla K. (1996). Cancer Res., 56, 4743-4748.
23. Jarvis WD, Johnson CR, Fornari FA, Park JS, Dent P and Grant S. (1999). J. Pharmacol. Exp. Ther., 290, 1384-1392.
24. Kennedy SG, Kandel ES, Cross TK and Hay N. (1999). Mol. Cell Biol., 19, 5800-5810.
25. Kummer JL, Rao PK and Heidenreich KA. (1997). J. Biol. Chem., 272, 20490-20494.
26. Lali FV, Hunt AE, Turner SJ and Foxwell BM. (2000). J. Biol. Chem., 275, 7395-7402.
27. MacFarlane M, Cohen GM and Dickens M. (2000). Biochem. J., 348, 93-101.
28. Mackay K and Mochly-Rosen D. (1999). J. Biol. Chem., 274, 6272-6279.
29. MacKeigan JP, Collins TS and Ting JP. (2000). J. Biol. Chem., 275, 38953-38956.
30. Mandlekar S, Yu R, Tan TH and Kong AN. (2000). Cancer Res., 60, 5995-6000.
31. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F and Riccardi C. (1991). J. Immunol. Methods, 139, 271-279.
32. Oh-hashi K, Maruyama W, Yi H, Takahashi T, Naoi M and Isobe K. (1999). Biochem. Biophys. Res. Commun., 263, 504-509.
33. Sanchez-Perez I, Martinez-Gomariz M, Williams D, Keyse SM and Perona R. (2000). Oncogene, 19, 5142-5152.
34. Shiah SG, Chuang SE, Chau YP, Shen SC and Kuo ML. (1999). Cancer Res., 59, 391-398.
35. Shiah SG, Chuang SE and Kuo ML. (2001). Mol. Pharmacol., 59, 254-262.
36. Tang D, Okada H, Ruland J, Liu L, Stambolic V, Mak TW and Ingram AJ. (2001). J. Biol. Chem., 276, 30461-30466.
37. Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, Jones SN, Flavell RA and Davis RJ. (2000). Science, 288, 870-874.
38. Wang TH, Wang HS and Soong YK. (2000). Cancer, 88, 2619-2628.
39. Watabe M, Kakeya H and Osada H. (1999). Oncogene, 18, 5211-5220.
40. Xia Z, Dickens M, Raingeaud J, Davis RJ and Greenberg ME. (1995). Science, 270, 1326-1331.
41. Yen A, Robertson MS, Varvayanis S and Lee AT. (1998). Cancer Res., 58, 3163-3172.
42. Zanke BW, Boudreau K, Rubie E, Winnett E, Tibbles LA, Zon L, Kyriakis J, Liu FF and Woodgett JR. (1996). Curr. Biol., 6, 606-613.
43. Zechner D, Craig R, Hanford DS, McDonough PM, Sabbadini RA and Glembotski CC. (1998). J. Biol. Chem., 273, 8232-8239.
44. Zhuang S, Demirs JT and Kochevar IE. (2000). J. Biol. Chem., 275, 25939-25948.