The return of the INGs, histone mark sensors and phospholipid signaling effectors

Current Drug Targets

Volumn 10, Issue 5, 2009, Pages 418-431

  Bua, Dennis J ^a   Binda, Olivier ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Chromatin; H3K4me3; ING; PHD finger; Phosphoinositide; PtdIns(5)P; Tumor suppressor

Indexed keywords

HISTONE H3; HISTONE H3 TRIMETHYLATED AT LYSINE 4; HOMEODOMAIN PROTEIN; INHIBITOR OF GROWTH PROTEIN; INHIBITOR OF GROWTH PROTEIN 1; INHIBITOR OF GROWTH PROTEIN 2; INHIBITOR OF GROWTH PROTEIN 3; INHIBITOR OF GROWTH PROTEIN 4; INHIBITOR OF GROWTH PROTEIN 5; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; PHOSPHOLIPID; PLANT HOMEODOMAIN PROTEIN; REGULATOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; HISTONE; PHOSPHATIDYLINOSITOL 5-PHOSPHATE; POLYPHOSPHOINOSITIDE;

AUTOIMMUNE DISEASE; CELL FUNCTION; CELL GROWTH; CELLULAR STRESS RESPONSE; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; IMMUNE DEFICIENCY; NEOPLASM; NEUROLOGIC DISEASE; NONHUMAN; PHOSPHOLIPID METABOLISM; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; CELL PROLIFERATION; CHROMATIN; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL PROLIFERATION; CHROMATIN; GENE EXPRESSION REGULATION; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; PHOSPHATIDYLINOSITOL PHOSPHATES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 67650610077     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945009788185112     Document Type: Review

References (174)

1. Luger, K.; Mader, A.W.; Richmond, R.K.; Sargent, D.F. and Richmond, T.J. (1997) Nature, 389(6648), 251-260.
2. Thoma, F. and Koller, T. (1977) Cell, 12(1), 101-107.
3. Strahl, B.D. and Allis, C.D. (2000) Nature, 403(6765), 41-45.
4. Turner, B.M. (2007) Nat. Cell Biol., 9(1), 2-6.
5. Ruthenburg, A.J.; Li, H.; Patel, D.J. and David Allis, C. (2007) Nat. Rev. Mol. Cell Biol., 8(12), 983-994.
6. Taverna, S.D.; Li, H.; Ruthenburg, A.J.; Allis, C.D. and Patel, D.J. (2007) Nat. Struct. Mol. Biol., 14(11), 1025-1040.
7. Liang, G.; Lin, J.C.Y.; Wei, V.; Yoo, C.; Cheng, J.C.; Nguyen, C.T.; Weisenberger, D.J.; Egger, G.; Takai, D.; Gonzales, F.A. and Jones, P.A. (2004) Proc. Natl. Acad. Sci., 101(19), 7357-7362.
8. Roh, T.-Y.; Cuddapah, S. and Zhao, K. (2005) Gene Dev., 19(5), 542-552.
9. Anderson, J.D.; Lowary, P.T. and Widom, J. (2001) J. Mol. Biol., 307(4), 977-985.
10. Hong, L.; Schroth, G.; Matthews, H.; Yau, P. and Bradbury, E. (1993) J. Biol. Chem., 268(1), 305-314.
11. Lee, D.Y.; Hayes, J.J.; Pruss, D. and Wolffe, A.P. (1993) Cell, 72(1), 73-84.
12. Wolffe, A.P. and Hayes, J.J. (1999) Nucl. Acids Res., 27(3), 711-720.
13. Dhalluin, C.; Carlson, J.E.; Zeng, L.; He, C.; Aggarwal, A.K. and Zhou, M.-M. (1999) Nature, 399(6735), 491-496.
14. Jacobson, R.H.; Ladurner, A.G.; King, D.S. and Tjian, R. (2000) Science, 288(5470), 1422-1425.
15. Durrin, L.K.; Mann, R.K.; Kayne, P.S. and Grunstein, M. (1991) Cell, 65(6), 1023-1031.
16. Taunton, J.; Hassig, C.A. and Schreiber, S.L. (1996) Science, 272(5260), 408-411.
17. Kuo, M.-H.; Brownell, J.E.; Sobel, R.E.; Ranalli, T.A.; Cook, R.G.; Edmondson, D.G.; Roth, S.Y. and Allis, C.D. (1996) Nature, 383(6597), 269-272.
18. Noma, K.-I.; Allis, C.D.; and Grewal, S.I.S. (2001) Science, 293(5532), 1150-1155.
19. Rea, S.; Eisenhaber, F.; O'Carroll, D.; Strahl, B.D.; Sun, Z.-W.; Schmid, M.; Opravil, S.; Mechtler, K.; Ponting, C.P.; Allis, C.D. and Jenuwein, T. (2000) Nature, 406(6796), 593-599.
20. Bannister, A.J.; Zegerman, P.; Partridge, J.F.; Miska, E.A.; Thomas, J.O.; Allshire, R.C. and Kouzarides, T. (2001) Nature, 410(6824), 120-124.
21. Barski, A.; Cuddapah, S.; Cui, K.; Roh, T.-Y.; Schones, D.E.; Wang, Z.; Wei, G.; Chepelev, I. and Zhao, K. (2007) Cell, 129(4), 823-837.
22. Schneider, R.; Bannister, A.J.; Myers, F.A.; Thorne, A.W.; Crane-Robinson, C. and Kouzarides, T. (2004) Nat. Cell Biol., 6(1), 73-77.
23. Santos-Rosa, H.; Schneider, R.; Bannister, A.J.; Sherriff, J.; Bernstein, B.E.; Emre, N.C.T.; Schreiber, S.L.; Mellor, J. and Kouzarides, T. (2002) Nature, 419(6905), 407-411.
24. Jenuwein, T. and Allis, C.D. (2001) Science, 293(5532), 1074-1080.
25. Wysocka, J.; Swigut, T.; Xiao, H.; Milne, T.A.; Kwon, S.Y.; Landry, J.; Kauer, M.; Tackett, A.J.; Chait, B.T.; Badenhorst, P.; Wu, C. and Allis, C.D. (2006) Nature, 442(7098), 86-90.
26. Shi, X.; Hong, T.; Walter, K.L.; Ewalt, M.; Michishita, E.; Hung, T.; Carney, D.; Peña, P.; Lan, F.; Kaadige, M.R.; Lacoste, N.; Cayrou, C.; Davrazou, F.; Saha, A.; Cairns, B.R.; Ayer, D.E.; Kutateladze, T.G.; Shi, Y.; Côté, J.; Chua, K.F. and Gozani, O. (2006) Nature, 442(7098), 96-99.
27. Matthews, A.G.W.; Kuo, A.J.; Ramon-Maiques, S.; Han, S.; Champagne, K.S.; Ivanov, D.; Gallardo, M.; Carney, D.; Cheung, P.; Ciccone, D.N.; Walter, K.L.; Utz, P.J.; Shi, Y.; Kutateladze, T.G.; Yang, W.; Gozani, O. and3 Oettinger, M.A. (2007) Nature, 450(7172), 1106-1110.
28. Ramón-Maiques, S.; Kuo, A.J.; Carney, D.; Matthews, A.G.W.; Oettinger, M.A.; Gozani, O. and Yang, W. (2007) Proc. Natl. Acad. Sci., 104(48), 18993-18998.
29. Shi, X.; Kachirskaia, I.; Walter, K.L.; Kuo, J.-H.A.; Lake, A.; Davrazou, F.; Chan, S.M.; Martin, D.G.E.; Fingerman, I.M.; Briggs, S.D.; Howe, L.; Utz, P.J.; Kutateladze, T.G.; Lugovskoy, A.A.; Bedford, M.T. and Gozani, O. (2007) J. Biol. Chem., 282(4), 2450-2455.
30. Kim, J.; Daniel, J.; Espejo, A.; Lake, A.; Krishna, M.; Xia, L.; Zhang, Y. and Bedford, M.T. (2006) EMBO Reports, 7(4), 397-403.
31. Lachner, M.; O'Carroll, D.; Rea, S.; Mechtler, K. and Jenuwein, T. (2001) Nature, 410(6824), 116-120.
32. Min, J.; Allali-Hassani, A.; Nady, N.; Qi, C.; Ouyang, H.; Liu, Y.; MacKenzie, F.; Vedadi, M. and Arrowsmith, C.H. (2007) Nat. Struct. Mol. Biol., 14(12), 1229-1230.
33. Huyen, Y.; Zgheib, O.; DiTullio Jr, R.A.; Gorgoulis, V.G.; Zacharatos, P.; Petty, T.J.; Sheston, E.A.; Mellert, H.S.; Stavridi, E.S. and Halazonetis, T.D. (2004) Nature, 432(7015), 406-411.
34. Collins, R.E.; Northrop, J.P.; Horton, J.R.; Lee, D.Y.; Zhang, X.; Stallcup, M.R. and Cheng, X. (2008) Nat. Struct. Mol. Biol., 15(3), 245-250.
35. Saksouk, N.; Avvakumov, N.; Champagne, K.S.; Hung, T.; Doyon, Y.; Cayrou, C.; Paquet, E.; Ullah, M.; Landry, A.-J.; Côté, V.; Yang, X.-J.; Gozani, O.; Kutateladze, T.G. and Côté, J. (2009) Mol. Cell, 33(2), 257-265.
36. Hung, T.; Binda, O.; Champagne, K.; Kuo, A.; Johnson, K.; Chang, H.; Simon, M.; Kutateladze, T. and Gozani, O. (2008) Mol. Cell.
37. He, G.H.Y.; Helbing, C.C.; Wagner, M.J.; Sensen, C.W. and Riabowol, K. (2005) Mol. Biol. Evol., 22(1), 104-116.
38. Saksouk, N.; Avvakumov, N. and Côté, J. (2008) Cell Mol. Life Sci., 65(7-8), 1013-1008.
39. Peña, P.V.; Hom, R.A.; Hung, T.; Lin, H.; Kuo, A.J.; Wong, R.P.C.; Subach, O.M.; Champagne, K.S.; Zhao, R.; Verkhusha, V.V.; Li, G.; Gozani, O. and Kutateladze, T.G. (2008) J. Mol. Biol., 380(2), 303-312.
40. Champagne, K.S.; Saksouk, N.; Peña, P.V.; Johnson, K.; Ullah, M.; Yang, X.-J.; Côté, J. and Kutateladze, T.G. (2008) Proteins, Structure, Function Bioinform, 72(4), 1371-1376.
41. Gozani, O.; Karuman, P.; Jones, D.R.; Ivanov, D.; Cha, J.; Lugovskoy, A.A.; Baird, C.L.; Zhu, H.; Field, S.J.; Lessnick, S.L.; Villasenor, J.; Mehrotra, B.; Chen, J.; Rao, V.R.; Brugge, J.S.; Ferguson, C.G.; Payrastre, B.; Myszka, D.G.; Cantley, L.C.; Wagner, G.; Divecha, N.; Prestwich, G.D. and Yuan, J. (2003) Cell, 114(1), 99-111.
42. Kaadige, M.R. and Ayer, D.E. (2006) J. Biol. Chem., 281(39), 28831-28836.
43. Doyon, Y.; Cayrou, C.; Ullah, M.; Landry, A.-J.; Côté, V.; Selleck, W.; Lane, W.S.; Tan, S.; Yang, X.-J. and Côté, J. (2006) Mol. Cell, 21(1), 51-64.
44. Skowyra, D.; Zeremski, M.; Neznanov, N.; Li, M.; Choi, Y.; Uesugi, M.; Hauser, C.A.; Gu, W.; Gudkov, A.V. and Qin, J. (2001) J. Biol. Chem., 276(12), 8734-8739.
45. Binda, O.; Nassif, C. and Branton, P.E. (2008) Oncogene, 27(24), 3384-3392.
46. Han, X.; Feng, X.; Rattner, J.B.; Smith, H.; Bose, P.; Suzuki, K.; Soliman, M.A.; Scott, M.S.; Burke, B.E. and Riabowol, K. (2008) Nat. Cell Biol., 10(11), 1333-1340.
47. Dechat, T.; Pfleghaar, K.; Sengupta, K.; Shimi, T.; Shumaker, D.K.; Solimando, L. and Goldman, R.D. (2008) Genes Dev., 22(7), 832-853.
48. Scott, M.; Bonnefin, P.; Vieyra, D.; Boisvert, F.-M.; Young, D.; Bazett-Jones, D.P. and Riabowol, K. (2001) J. Cell Sci., 114(19), 3455-3462.
49. Shi, X. and Gozani, O. (2005) J. Cell. Biochem., 96(6), 1127-1136.
50. Kuzmichev, A.; Zhang, Y.; Erdjument-Bromage, H.; Tempst, P. and Reinberg, D. (2002) Mol. Cell. Biol., 22(3), 835-848.
51. Doyon, Y.; Selleck, W.; Lane, W.S.; Tan, S. and Côté, J. (2004) Mol. Cell Biol., 24(5), 1884-1896.
52. Ythier, D.; Larrieu, D.; Brambilla, C.; Brambilla, E. and Pedeux, R. (2008) Inter. J. Cancer, 123(7), 1483-1490.
53. Cengiz, B.; Gunduz, M.; Nagatsuka, H.; Beder, L.; Gunduz, E.; Tamamura, R.; Mahmut, N.; Fukushima, K.; Ali, M.A.S.; Naomoto, Y.; Shimizu, K. and Nagai, N. (2007) Oral oncology, 43(3), 241-247.
54. Baker, L.A.; Allis, C.D. and Wang, G.G. (2008) Mutation Research/ Fundamental Mol. Mech. Mutagenesis, 647(1-2), 3-12.
55. Liu, Y.; Subrahmanyam, R.; Chakraborty, T.; Sen, R. and Desiderio, S. (2007) Immunity, 27(4), 561-571.
56. Iberg, A.N.; Espejo, A.; Cheng, D.; Kim, D.; Michaud-Lévesque, J.; Richard, S. and Bedford, M.T. (2008) J. Biol. Chem., 283(6), 3006-3010.
57. Koh, A.S.; Kuo, A.J.; Park, S.Y.; Cheung, P.; Abramson, J.; Bua, D.; Carney, D.; Shoelson, S.E.; Gozani, O.; Kingston, R.E.; Benoist, C. and Mathis, D. (2008) Proc. Natl. Acad. Sci., 105(41), 15878-15883.
58. Org, T.; Chignola, F.; Hetényi, C.; Gaetani, M.; Rebane, A.; Liiv, I.; Maran, U.; Mollica, L.; Bottomley, M.J.; Musco, G. and Peterson, P. (2008) EMBO Reports, 9(4), 370-376.
59. Garkavtsev, I.; Kazarov, A.; Gudkov, A. and Riabowol, K. (1996) Nat. Genet., 14(4), 415-420.
60. Vieyra, D.; Loewith, R.; Scott, M.; Bonnefin, P.; Boisvert, F.-M.; Cheema, P.; Pastyryeva, S.; Meijer, M.; Johnston, R.N.; Bazett-Jones, D.P.; McMahon, S.; Cole, M.D.; Young, D. and Riabowol, K. (2002) J. Biol. Chem., 277(33), 29832-29839.
61. Gunduz, M.; Ouchida, M.; Fukushima, K.; Hanafusa, H.; Etani, T.; Nishioka, S.; Nishizaki, K. and Shimizu, K. (2000) Cancer Res., 60(12), 3143-3146.
62. Chen, L.; Matsubara, N.; Yoshino, T.; Nagasaka, T.; Hoshizima, N.; Shirakawa, Y.; Naomoto, Y.; Isozaki, H.; Riabowol, K. and Tanaka, N. (2001) Cancer Res., 61(11), 4345-4349.
63. Garkavtsev, I.; Grigorian, I.A.; Ossovskaya, V.S.; Chernov, M.V.; Chumakov, P.M. and Gudkov, A.V. (1998) Nature, 391(6664), 295-298.
64. Garkavtsev, I. and Riabowol, K. (1997) Mol. Cell Biol., 17(4), 2014-2019.
65. Kichina, J.V.; Zeremski, M.; Aris, L.; Gurova, K.V.; Walker, E.; Franks, R.; Nikitin, A.Y.; Kiyokawa, H. and Gudkov, A.V. (2005) Oncogene, 25(6), 857-866.
66. Coles, A.H.; Liang, H.; Zhu, Z.; Marfella, C.G.A.; Kang, J.; Imbalzano, A.N. and Jones, S.N. (2007) Cancer Res., 67(5), 2054-2061.
67. Unoki, M.; Kumamoto, K.; Robles, A.I.; Shen, J.C.; Zheng, Z.-M. and Harris, C.C. (2008) FEBS lett., 582(28), 3868-3874.
68. Backsch, C.; Rudolph, B.; Kühne-Heid, R.; Kalscheuer, V.; Bartsch, O.; Jansen, L.; Beer, K.; Meyer, B.; Schneider, A. and Dürst, M. (2005) Genes Chromosomes Cancer, 43(3), 260-272.
69. Cetin, E.; Cengiz, B.; Gunduz, E.; Gunduz, M.; Nagatsuka, H.; Bekir-Beder, L.; Fukushima, K.; Pehlivan, D.; N, M.; Nishizaki, K.; Shimizu, K. and Nagai, N. (2008) Neoplasma, 55(4), 299-304.
70. Sironi, E.; Cerri, A.; Tomasini, D.; Sirchia, S.M.; Porta, G.; Rossella, F.; Grati, F.R. and Simoni, G. (2004) J. Cutaneous Path., 31(4), 318-322.
71. Zhanga, H.-k.; Pana, K.; Wanga, H.; Wenga, D.-s.; Songa, H.-f.; Zhoua, J.; Huanga, W.; Lia, J.-j.; Chenb, M.-s. and Xia, J.-c. (2008) Cancer Lett., 261(2), 183-192.
72. Lu, F.; Dai, D.; Martinka, M.; Ho, V. and Li, G. (2006) Br. J. Cancer, 95(1), 80-86.
73. Pedeux, R.; Sengupta, S.; Shen, J.C.; Demidov, O.N.; Saito, S.i.; Onogi, H.; Kumamoto, K.; Wincovitch, S.; Garfield, S.H.; McMenamin, M.; Nagashima, M.; Grossman, S.R.; Appella, E. and Harris, C.C. (2005) Mol. Cell. Biol., 25(15), 6639-6648.
74. Colina, A.R. and Young, D. (2005) J. Biol. Chem., 280(52), 42552-42556.
75. Carrozza, M.J.; Florens, L.; Swanson, S.K.; Shia, W.-J.; Anderson, S.; Yates, J.; Washburn, M.P. and Workman, J.L. (2005) Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1731(2), 77-87.
76. Loewith, R.; Smith, J.S.; Meijer, M.; Williams, T.J.; Bachman, N.; Boeke, J.D. and Young, D. (2001) J. Biol. Chem., 276(26), 24068-24074.
77. Nourani, A.; Howe, L.; Pray-Grant, M.G.; Workman, J.L.; Grant, P.A. and Côté, J. (2003) J. Biol. Chem., 278(21), 19171-19175.
78. Goeman, F.; Otto, K.; Kyrylenko, S.; Schmidt, O.; and Baniahmad, A. (2008) Biochim. Biophys. Acta (BBA) - Mol. Cell Res., 1783(10), 1673-1680.
79. Nagashima, M.; Shiseki, M.; Pedeux, R.M.; Miura, K.; Kitahama-Shiseki, M.; Miura, K.; Yokota, J. and Harris, C.C. (2003) Oncogene, 22(3), 343-350.
80. Gunduz, M.; Ouchida, M.; Fukushima, K.; Ito, S.; Jitsumori, Y.; Nakashima, T.; Nagai, N.; Nishizaki, K. and Shimizu, K. (2002) Oncogene, 21(28), 4462-4470.
81. Wang, Y. and Li, G. (2006) J. Biol. Chem., 281(17), 11887-11893.
82. Shiseki, M.; Nagashima, M.; Pedeux, R.M.; Kitahama-Shiseki, M.; Miura, K.; Okamura, S.; Onogi, H.; Higashimoto, Y.; Appella, E.; Yokota, J. and Harris, C.C. (2003) Cancer Res., 63(10), 2373-2378.
83. Gunduz, M.; Nagatsuka, H.; Demircan, K.; Gunduz, E.; Cengiz, B.; Ouchida, M.; Tsujigiwa, H.; Yamachika, E.; Fukushima, K.; Beder, L.; Hirohata, S.; Ninomiya, Y.; Nishizaki, K.; Shimizu, K. and Nagai, N. (2005) Gene, 356, 109-117.
84. Foy, R.L.; Song, I.Y.; Chitalia, V.C.; Cohen, H.T.; Saksouk, N.; Cayrou, C.; Vaziri, C.; Côté, J. and Panchenko, M.V. (2008) J. Biol. Chem., 283(43), 28817-28826.
85. Kim, S.; Chin, K.; Gray, J.W. and Bishop, J.M. (2004) Proc. Natl. Acad. Sci., 101(46), 16251-16256.
86. Nagashima, M.; Shiseki, M.; Miura, K.; Hagiwara, K.; Linke, S.P.; Pedeux, R.; Wang, X.W.; Yokota, J.; Riabowol, K. and Harris, C.C. (2001) Proc. Natl. Acad. Sci., 98(17), 9671-9676.
87. Shi, X.; Kachirskaia, I.; Yamaguchi, H.; West, L.E.; Wen, H.; Wang, E.W.; Dutta, S.; Appella, E. and Gozani, O. (2007) Mol. Cell, 27(4), 636-646.
88. Peña, P.V.; Musselman, C.A.; Kuo, A.J.; Gozani, O. and Kutateladze, T.G. (2009) Magnetic Resonance in Chemistry, DOI, 10.1002/ mrc.2390(Epub ahead of print).
89. Langley, E.; Pearson, M.; Faretta, M.; Bauer, U.-M.; Frye, R.A.; Minucci, S.; Pelicci, P.G. and Kouzarides, T. (2002) EMBO J., 21(10), 2383-2396.
90. Vaziri, H.; Dessain, S.K.; Eaton, E.N.; Imai, S.-I.; Frye, R.A.; Pandita, T.K.; Guarente, L. and Weinberg, R.A. (2001) Cell, 107(2), 149-159.
91. Furukawa, A.; Tada-Oikawa, S.; Kawanishi, S. and Oikawa, S. (2007) Cell Physiol. Biochem., 20(1-4), 045-054.
92. Sasaki, T.; Maier, B.; Bartke, A.; and Scrable, H. (2006) Aging Cell, 5(5), 413-422.
93. Sommer, M.; Poliak, N.; Upadhyay, S.; Ratovitski, E.; Nelkin, B.; Donehower, L. and Sidransky, D. (2006) Cell Cycle, 5(17), 2005-2011.
94. Huang, J.; Gan, Q.; Han, L.; Li, J.; Zhang, H.; Sun, Y.; Zhang, Z. and Tong, T. (2008) PLoS ONE, 3(3), e1710.
95. Kumamoto, K.; Spillare, E.A.; Fujita, K.; Horikawa, I.; Yamashita, T.; Appella, E.; Nagashima, M.; Takenoshita, S.; Yokota, J. and Harris, C.C. (2008) Cancer Res., 68(9), 3193-3203.
96. Hung, T.; Binda, O.; Champagne, K.S.; Kuo, A.J.; Johnson, K.; Chang, H.Y.; Simon, M.D.; Kutateladze, T.G. and Gozani, O. (2009) Mol. Cell, 33(2), 248-256.
97. Murphy, M.; Ahn, J.; Walker, K.K.; Hoffman, W.H.; Evans, R.M.; Levine, A.J. and George, D.L. (1999) Genes Dev., 13(19), 2490-2501.
98. Zilfou, J.T.; Hoffman, W.H.; Sank, M.; George, D.L. and Murphy, M. (2001) Mol. Cell Biol., 21(12), 3974-3985.
99. Leung, K.M.; Po, L.S.; Tsang, F.C.; Siu, W.Y.; Lau, A.; Ho, H.T.B. and Poon, R.Y.C. (2002) Cancer Res., 62(17), 4890-4893.
100. Peã, P.V.; Davrazou, F.; Shi, X.; Walter, K.L.; Verkhusha, V.V.; Gozani, O.; Zhao, R. and Kutateladze, T.G. (2006) Nature, 442(7098), 100-103.
101. Palacios, A.; Muñoz, I.G.; Pantoja-Uceda, D.; Marcaida, M.J.; Torres, D.; Martín-García, J.M.; Luque, I.; Montoya, G. and Blanco, F.J. (2008) J. Biol. Chem., 283(23), 15956-15964.
102. Li, H.; Ilin, S.; Wang, W.; Duncan, E.M.; Wysocka, J.; Allis, C.D. and Patel, D.J. (2006) Nature, 442(7098), 91-95.
103. van Ingen, H.; van Schaik, F.M.A.; Wienk, H.; Ballering, J.; Rehmann, H.; Dechesne, A.C.; Kruijzer, J.A.W.; Liskamp, R.M.J.; Timmers, H.T.M. and Boelens, R. (2008) Structure, 16(8), 1245-1256.
104. Flanagan, J.F.; Mi, L.-Z.; Chruszcz, M.; Cymborowski, M.; Clines, K.L.; Kim, Y.; Minor, W.; Rastinejad, F. and Khorasanizadeh, S. (2005) Nature, 438(7071), 1181-1185.
105. Lan, F.; Collins, R.E.; De Cegli, R.; Alpatov, R.; Horton, J.R.; Shi, X.; Gozani, O.; Cheng, X. and Shi, Y. (2007) Nature, 448(7154), 718-722.
106. Martin, D.G.E.; Baetz, K.; Shi, X.; Walter, K.L.; MacDonald, V.E.; Wlodarski, M.J.; Gozani, O.; Hieter, P. and Howe, L. (2006) Mol. Cell Biol., 26(21), 7871-7879.
107. Aparicio, J.G.; Viggiani, C.J.; Gibson, D.G. and Aparicio, O.M. (2004) Mol. Cell Biol., 24(11), 4769-4780.
108. David, G.; Dannenberg, J.H.; Simpson, N.; Finnerty, P.M.; Miao, L.; Turner, G.M.; Ding, Z.; Carrasco, R. and DePinho, R.A. (2006) Oncogene.
109. David, G.; Turner, G.M.; Yao, Y.; Protopopov, A. and DePinho, R.A. (2003) Genes Dev., 17(19), 2396-2405.
110. Dannenberg, J.-H.; David, G.; Zhong, S.; van der Torre, J.; Wong, W.H. and DePinho, R.A. (2005) Genes Dev., 19(13), 1581-1595.
111. Garkavtsev, I.; Kozin, S.V.; Chernova, O.; Xu, L.; Winkler, F.; Brown, E.; Barnett, G.H. and Jain, R.K. (2004) Nature, 428(6980), 328-332.
112. Rankin, E.B. and Giaccia, A.J. (2008) Cell Death Diff., 15(4), 678-685.
113. Colla, S.; Tagliaferri, S.; Morandi, F.; Lunghi, P.; Donofrio, G.; Martorana, D.; Mancini, C.; Lazzaretti, M.; Mazzera, L.; Ravanetti, L.; Bonomini, S.; Ferrari, L.; Miranda, C.; Ladetto, M.; Neri, T.M.; Neri, A.; Greco, A.; Mangoni, M.; Bonati, A.; Rizzoli, V. and Giuliani, N. (2007) Blood, 110(13), 4464-4475.
114. Ozer, A. and Bruick, R.K. (2005) Cell Cycle, 4(9), 1153-1156.
115. Ozer, A.; Wu, L.C. and Bruick, R.K. (2005) Proc. Natl. Acad. Sci., 102(21), 7481-7486.
116. Kaelin Jr, W.G. (2008) Nat. Rev. Cancer, 8(11), 865-873.
117. Kim, W. and Kaelin Jr, W.G. (2003) Curr. Opi. Genet. Dev., 13(1), 55-60.
118. Zhang, X.; Xu, L.-S.; Wang, Z.-Q.; Wang, K.-S.; Li, N.; Cheng, Z.H.; Huang, S.-Z.; Wei, D.-Z. and Han, Z.-G. (2004) FEBS lett., 570(1), 7-12.
119. Kim, S. (2005) Cell Cycle, 4(4), 516-517.
120. Gozani, O.; Field, S.J.; Ferguson, C.G.; Ewalt, M.; Mahlke, C.; Cantley, L.C.; Prestwich, G.D. and Yuan, J. (2005) Adv. Enzyme Reg., 45(1), 171-185.
121. Clarke, J.H. (2003) Curr. Biol., 13(20), R815-R817.
122. Jones, D.R. and Divecha, N. (2004) Cur. Opi. Genet. Dev., 14(2), 196-202.
123. Bunce, M.W.; Gonzales, M.L. and Anderson, R.A. (2006) Sci. STKE, 2006(360), pe46.
124. Irvine, R.F. (2002) Sci. STKE, 2002(150), re13.
125. D'Santos, C.S.; Clarke, J.H. and Divecha, N. (1998) Biochim. Biophys. Acta (BBA) - Mol. Cell Biol. Lipids, 1436(1-2), 201-232.
126. Huang, W.; Zhang, H.; Davrazou, F.; Kutateladze, T.G.; Shi, X.; Gozani, O. and Prestwich, G.D. (2007) J. Am. Chem. Society, 129(20), 6498-6506.
127. Smith, C.D. and Wells, W.W. (1983) J. Biol. Chem., 258(15), 9368-9373.
128. Cocco, L.; Gilmour, R.; Ognibene, A.; Letcher, A.; Manzoli, F. and Irvine, R. (1987) Biochem. J., 248(3), 765-770.
129. Vann, L.R.; Wooding, F.B.; Irvine, R.F. and Divecha, N. (1997) Biochem. J., 327(2), 569-576.
130. D'Santos, C.S.; Clarke, J.H.; Irvine, R.F. and Divecha, N. (1999) Curr. Biol., 9(8), 437-440.
131. Asano, M.; Tamiya-Koizumi, K.; Homma, Y.; Takenawa, T.; Nimura, Y.; Kojima, K. and Yoshida, S. (1994) J. Biol. Chem., 269(16), 12360-12366.
132. Liu, N.; Fukami, K.; Yu, H. and Takenawa, T. (1996) J. Biol. Chem., 271(1), 355-360.
133. Hunt, A.N.; Clark, G.T.; Attard, G.S. and Postle, A.D. (2001) J. Biol. Chem., 276(11), 8492-8499.
134. Zhao, K.; Wang, W.; Rando, O.J.; Xue, Y.; Swiderek, K.; Kuo, A. and Crabtree, G.R. (1998) Cell, 95(5), 625-636.
135. Rando, O.J.; Zhao, K.; Janmey, P. and Crabtree, G.R. (2002) Proc. Natl. Acad. Sci., 99(5), 2824-2829.
136. Janmey, P.A. (1994) Ann. Rev.Physiol., 56(1), 169-191.
137. Yu, H.; Fukami, K.; Watanabe, Y.; Ozaki, C. and Takenawa, T. (1998) Eur. J. Biochem., 251(1-2), 281-287.
138. Steger, D.J.; Haswell, E.S.; Miller, A.L.; Wente, S.R. and O'Shea, E.K. (2003) Science, 299(5603), 114-116.
139. Shen, X.; Xiao, H.; Ranallo, R.; Wu, W.-H. and Wu, C. (2003) Science, 299(5603), 112-114.
140. Jones, D.R.; Bultsma, Y.; Keune, W.-J.; Halstead, J.R.; Elouarrat, D.; Mohammed, S.; Heck, A.J.; D'Santos, C.S. and Divecha, N. (2006) Mol. Cell, 23(5), 685-695.
141. Rameh, L.E.; Tolias, K.F.; Duckworth, B.C. and Cantley, L.C. (1997) Nature, 390(6656), 192-196.
142. Richardson, J.P.; Wang, M.; Clarke, J.H.; Patel, K.J. and Irvine, R.F. (2007) Cell Signal., 19(6), 1309-1314.
143. Nair, R.; Carter, P. and Rost, B. (2003) Nucl. Acids Res., 31(1), 397-399.
144. Bahk, Y.Y.; Lee, Y.H.; Lee, T.G.; Seo, J.; Ryu, S.H. and Suh, P.G. (1994) J. Biol. Chem., 269(11), 8240-8245.
145. Sbrissa, D.; Ikonomov, O.C. and Shisheva, A. (1999) J. Biol. Chem., 274(31), 21589-21597.
146. Shisheva, A.; Rusin, B.; Ikonomov, O.C.; DeMarco, C. and Sbrissa, D. (2001) J. Biol. Chem., 276(15), 11859-11869.
147. Cabezas, A.; Pattni, K. and Stenmark, H. (2006) Gene, 371(1), 34-41.
148. Bankaitis, V.A.; Phillips, S.; Yanagisawa, L.; Li, X.; Routt, S.M. and Xie, Z. (2005) Adv. Enzyme Reg., 45(1), 155-170.
149. Phillips, S.E.; Vincent, P.; Rizzieri, K.E.; Schaaf, G.; Bankaitis, V.A. and Gaucher, E.A. (2006) Crit. Rev. Biochem. Mol. Biol., 41(1), 21-49.
150. Hunt, A.N.; Alb, J.G.; Koster, G.; Postle, A.D. and Bankaitis, V.A. (2004) Biochem. Soc. Trans., 32(Pt 6), 1063-1065.
151. Routt, S.M. and Bankaitis, V.A. (2004) Biochem. Cell Biol., 82(1), 254-262.
152. Nakai, K. and Horton, P. (1999) Trends Biochem. Sci., 24(1), 34-35.
153. la Cour, T.; Kiemer, L.; Molgaard, A.; Gupta, R.; Skriver, K. and Brunak, S. (2004) Protein Eng., Design Selection, 17(6), 527-536.
154. Clague, M.J. and Lorenzo, O. (2005) Traffic, 6(12), 1063-1069.
155. Laporte, J.; Hu, L.J.; Kretz, C.; Mandel, J.-L.; Kioschis, P.; Coy, J.F.; Klauck, S.M.; Poustka, A. and Dahl, N. (1996) Nat. Genet., 13(2), 175-182.
156. Bolino, A.; Muglia, M.; Conforti, F.L.; LeGuern, E.; Salih, M.A.M.; Georgiou, D.-M.; Christodoulou, K.; Hausmanowa- Petrusewicz, I.; Mandich, P.; Schenone, A.; Gambardella, A.; Bono, F.; Quattrone, A.; Devoto, M. and Monaco, A.P. (2000) Nat. Genet., 25(1), 17-19.
157. Azzedine, H.; Bolino, A.; Taïeb, T.; Birouk, N.; Di Duca, M.; Bouhouche, A.; Benamou, S.; Mrabet, A.; Hammadouche, T.; Chkili, T.; Gouider, R.; Ravazzolo, R.; Brice, A.; Laporte, J. and LeGuern, E. (2003) Am. J. Human Genet., 72(5), 1141-1153.
158. MacKeigan, J.P.; Murphy, L.O. and Blenis, J. (2005) Nat. Cell Biol., 7(6), 591-600.
159. Kim, S.-A.; Vacratsis, P.O.; Firestein, R.; Cleary, M.L. and Dixon, J.E. (2003) Proc. Natl. Acad. Sci., 100(8), 4492-4497.
160. De Matteis, M.A. and Godi, A. (2004) Nat. Cell Biol., 6(6), 487-492.
161. Narayan, K. and Lemmon, M.A. (2006) Methods, 39(2), 122-133.
162. Mortier, E.; Wuytens, G.; Leenaerts, I.; Hannes, F.; Heung, M.Y.; Degeest, G.; David, G. and Zimmermann, P. (2005) EMBO J., 24(14), 2556-2565.
163. Papayannopoulos, V.; Co, C.; Prehoda, K.E.; Snapper, S.; Taunton, J. and Lim, W.A. (2005) Mol. Cell, 17(2), 181-191.
164. Heo, W.D.; Inoue, T.; Park, W.S.; Kim, M.L.; Park, B.O.; Wandless, T.J. and Meyer, T. (2006) Science, 314(5804), 1458-1461.
165. Viiri, K.M.; Janis, J.; Siggers, T.; Heinonen, T.Y.K.; Valjakka, J.; Bulyk, M.L.; Maki, M. and Lohi, O. (2008) Mol. Cell Biol., MCB.01213-08.
166. Elkin, S.K.; Ivanov, D.; Ewalt, M.; Ferguson, C.G.; Hyberts, S.G.; Sun, Z.-Y.J.; Prestwich, G.D.; Yuan, J.; Wagner, G.; Oettinger, M.A. and Gozani, O.P. (2005) J. Biol. Chem., 280(31), 28701-28710.
167. Russell, M.W.; Soliman, M.A.; Schriemer, D. and Riabowol, K. (2008) Biochem. Biophys. Res. Commun., 374(3), 490-495.
168. Pendaries, C.; Tronchère, H.; Arbibe, L.; Mounier, J.; Gozani, O.; Cantley, L.; Fry, M.J.; Gaits-Iacovoni, F.; Sansonetti, P.J. and Payrastre, B. (2006) EMBO J., 25(5), 1024-1034.
169. Zou, J.; Marjanovic, J.; Kisseleva, M.V.; Wilson, M.; and Majerus, P.W. (2007) Proc. Natl. Acad. Sci., 104(43), 16834-16839.
170. Ungewickell, A.; Hugge, C.; Kisseleva, M.; Chang, S.-C.; Zou, J.; Feng, Y.; Galyov, E.E.; Wilson, M. and Majerus, P.W. (2005) Proc. Natl. Acad. Sci., 102(52), 18854-18859.
171. Pagliarini, D.J.; Worby, C.A. and Dixon, J.E. (2004) J. Biol. Chem., 279(37), 38590-38596.
172. Wilcox, A. and Hinchliffe, K.A. (2008) FEBS Lett., 582(9), 1391-1394.
173. York, J.D. and Majerus, P.W. (1994) J. Biol. Chem., 269(11), 7847-7850.
174. Clarke, J.H.; Letcher, A.J.; D'Santos C, S.; Halstead, J.R.; Irvine, R.F. and Divecha, N. (2001) Biochem. J., 357(Pt 3), 905-910.