-
1
-
-
0028861418
-
The PHD finger: Implications for chromatin-mediated transcriptional regulation
-
Aasland, R., T. J. Gibson, and A. F. Stewart. 1995. The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem. Sci. 20:56-59.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 56-59
-
-
Aasland, R.1
Gibson, T.J.2
Stewart, A.F.3
-
2
-
-
0034818446
-
Post-translational modifications and activation of p53 by genotoxic stresses
-
Appella, E., and C. W. Anderson. 2001. Post-translational modifications and activation of p53 by genotoxic stresses. Eur. J. Biochem. 268:2764-2772.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2764-2772
-
-
Appella, E.1
Anderson, C.W.2
-
3
-
-
0029111404
-
Increased activity of p53 in senescing fibroblasts
-
Atadja, P., H. Wong, I. Garkavtsev, C. Veillette, and K. Riabowol. 1995. Increased activity of p53 in senescing fibroblasts. Proc. Natl. Acad. Sci. USA 92:8348-8352.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8348-8352
-
-
Atadja, P.1
Wong, H.2
Garkavtsev, I.3
Veillette, C.4
Riabowol, K.5
-
4
-
-
2542536710
-
Disappearance of the telomere dysfunction-induced stress response in fully senescent cells
-
Bakkenist, C. J., R. Drissi, J. Wu, M. B. Kastan, and J. S. Dome. 2004. Disappearance of the telomere dysfunction-induced stress response in fully senescent cells. Cancer Res. 64:3748-3752.
-
(2004)
Cancer Res.
, vol.64
, pp. 3748-3752
-
-
Bakkenist, C.J.1
Drissi, R.2
Wu, J.3
Kastan, M.B.4
Dome, J.S.5
-
5
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
Beausejour, C. M., A. Krtolica, F. Galimi, M. Narita, S. W. Lowe, P. Yaswen, and J. Campisi. 2003. Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J. 22:4212-4222.
-
(2003)
EMBO J.
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yaswen, P.6
Campisi, J.7
-
6
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar, A. G., M. Ouellette, M. Frolkis, S. E. Holt, C. P. Chiu, G. B. Morin, C. B. Harley, J. W. Shay, S. Lichtsteiner, and W. E. Wright. 1998. Extension of life-span by introduction of telomerase into normal human cells. Science 279:349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
7
-
-
0029841549
-
Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence
-
Bond, J, M. Haughton, J. Blaydes, V. Gire, D. Wynford-Thomas, and F. Wyllie. 1996. Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence. Oncogene 13:2097-2104.
-
(1996)
Oncogene
, vol.13
, pp. 2097-2104
-
-
Bond, J.1
Haughton, M.2
Blaydes, J.3
Gire, V.4
Wynford-Thomas, D.5
Wyllie, F.6
-
8
-
-
0029024691
-
Mutant p53 rescues human diploid cells from senescence without inhibiting the induction of SDI1/WAF1
-
Bond, J. A., J. P. Blaydes, J. Rowson, M. F. Haughton, J. R. Smith, D. Wynford-Thomas, and F. S. Wyllie. 1995. Mutant p53 rescues human diploid cells from senescence without inhibiting the induction of SDI1/WAF1. Cancer Res. 55:2404-2409.
-
(1995)
Cancer Res.
, vol.55
, pp. 2404-2409
-
-
Bond, J.A.1
Blaydes, J.P.2
Rowson, J.3
Haughton, M.F.4
Smith, J.R.5
Wynford-Thomas, D.6
Wyllie, F.S.7
-
9
-
-
0032912802
-
Control of replicative life span in human cells: Barriers to clonal expansion intermediate between M1 senescence and M2 crisis
-
Bond, J. A., M. F. Haughton, J. M. Rowson, P. J. Smith, V. Gire, D. Wynford-Thomas, and F. S. Wyllie. 1999. Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis. Mol. Cell. Biol. 19:3103-3114.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3103-3114
-
-
Bond, J.A.1
Haughton, M.F.2
Rowson, J.M.3
Smith, P.J.4
Gire, V.5
Wynford-Thomas, D.6
Wyllie, F.S.7
-
10
-
-
0037377060
-
Ubiquitination, phosphorylation and acetylation: The molecular basis for p53 regulation
-
Brooks, C. L., and W. Gu. 2003. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr. Opin. Cell Biol. 15: 164-171.
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 164-171
-
-
Brooks, C.L.1
Gu, W.2
-
11
-
-
4644235697
-
Monoubiquitination: The signal for p53 nuclear export?
-
Brooks, C. L., M. Li, and W. Gu. 2004. Monoubiquitination: the signal for p53 nuclear export? Cell Cycle 3:436-438.
-
(2004)
Cell Cycle
, vol.3
, pp. 436-438
-
-
Brooks, C.L.1
Li, M.2
Gu, W.3
-
12
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T. R., R. Bernards, and R. Agami. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
13
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna, F., P. M. Reaper, L. Clay-Farrace, H. Fiegler, P. Carr, T. von Zglinicki, G. Saretzki, N. P. Carter, and S. P. Jackson. 2003. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426: 194-198.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
D'Adda Di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
14
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri, G. P., X. Lee, G. Basile, M. Acosta, G. Scott, C. Roskelley, E. E. Medrano, M. Linskens, I. Rubelj, O. Pereira-Smith, M. Peacocke, and J. Campisi. 1995. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 92:9363-9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
Peacocke, M.11
Campisi, J.12
-
15
-
-
0033572746
-
Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
-
Dumaz, N., and D. W. Meek. 1999. Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2. EMBO J. 18:7002-7010.
-
(1999)
EMBO J.
, vol.18
, pp. 7002-7010
-
-
Dumaz, N.1
Meek, D.W.2
-
16
-
-
0036850549
-
Different HATS of the ING1 gene family
-
Feng, X., Y. Hara, and K. Riabowol. 2002. Different HATS of the ING1 gene family. Trends Cell Biol. 12:532-538.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 532-538
-
-
Feng, X.1
Hara, Y.2
Riabowol, K.3
-
17
-
-
0034663873
-
PML is induced by oncogenic ras and promotes premature senescence
-
Ferbeyre, G., E. de Stanchina, E. Querido, N. Baptiste, C. Prives, and S. W. Lowe. 2000. PML is induced by oncogenic ras and promotes premature senescence. Genes Dev. 14:2015-2027.
-
(2000)
Genes Dev.
, vol.14
, pp. 2015-2027
-
-
Ferbeyre, G.1
De Stanchina, E.2
Querido, E.3
Baptiste, N.4
Prives, C.5
Lowe, S.W.6
-
18
-
-
0032518510
-
The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control
-
Garkavtsev, I., I. A. Grigorian, V. S. Ossovskaya, M. V. Chernov, P. M. Chumakov, and A. V. Gudkov. 1998. The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control. Nature 391:295-298.
-
(1998)
Nature
, vol.391
, pp. 295-298
-
-
Garkavtsev, I.1
Grigorian, I.A.2
Ossovskaya, V.S.3
Chernov, M.V.4
Chumakov, P.M.5
Gudkov, A.V.6
-
19
-
-
1642586297
-
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
-
Garkavtsev, I., S. V. Kozin, O. Chernova, L. Xu, F. Winkler, E. Brown, G. H. Barnett, and R. K. Jain. 2004. The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature 428:328-332.
-
(2004)
Nature
, vol.428
, pp. 328-332
-
-
Garkavtsev, I.1
Kozin, S.V.2
Chernova, O.3
Xu, L.4
Winkler, F.5
Brown, E.6
Barnett, G.H.7
Jain, R.K.8
-
20
-
-
0030900592
-
Extension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressor
-
Garkavtsev, I., and K. Riabowol. 1997. Extension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressor. Mol. Cell. Biol. 17:2014-2019.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2014-2019
-
-
Garkavtsev, I.1
Riabowol, K.2
-
21
-
-
3342929538
-
DNA damage checkpoint kinase Chk2 triggers replicative senescence
-
Gire, V., P. Roux, D. Wynford-Thomas, J. M. Brondello, and V. Dulic. 2004. DNA damage checkpoint kinase Chk2 triggers replicative senescence. EMBO J. 23:2554-2563.
-
(2004)
EMBO J.
, vol.23
, pp. 2554-2563
-
-
Gire, V.1
Roux, P.2
Wynford-Thomas, D.3
Brondello, J.M.4
Dulic, V.5
-
22
-
-
0031935827
-
Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies
-
Gire, V., and D. Wynford-Thomas. 1998. Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies. Mol. Cell. Biol. 18:1611-1621.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1611-1621
-
-
Gire, V.1
Wynford-Thomas, D.2
-
23
-
-
0038784526
-
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor
-
Gozani, O., P. Karuman, D. R. Jones, D. Ivanov, J. Cha, A. A. Lugovskoy, C. L. Baird, H. Zhu, S. J. Field, S. L. Lessnick, J. Villasenor, B. Mehrotra, J. Chen, V. R. Rao, J. S. Brugge, C. G. Ferguson, B, Payrastre, D. G. Myszka, L. C. Cantley, G. Wagner, N. Divecha, G. D. Prestwich, and J. Yuan. 2003. The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell 114:99-111.
-
(2003)
Cell
, vol.114
, pp. 99-111
-
-
Gozani, O.1
Karuman, P.2
Jones, D.R.3
Ivanov, D.4
Cha, J.5
Lugovskoy, A.A.6
Baird, C.L.7
Zhu, H.8
Field, S.J.9
Lessnick, S.L.10
Villasenor, J.11
Mehrotra, B.12
Chen, J.13
Rao, V.R.14
Brugge, J.S.15
Ferguson, C.G.16
Payrastre, B.17
Myszka, D.G.18
Cantley, L.C.19
Wagner, G.20
Divecha, N.21
Prestwich, G.D.22
Yuan, J.23
more..
-
24
-
-
0034824495
-
p300/CBP/p53 interaction and regulation of the p53 response
-
Grossman, S. R. 2001. p300/CBP/p53 interaction and regulation of the p53 response. Eur. J. Biochem. 268:2773-2778.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2773-2778
-
-
Grossman, S.R.1
-
25
-
-
0037432773
-
Polyubiquitination of p53 by a ubiquitin ligase activity of p300
-
Grossman, S. R., M. E. Deato, C. Brignone, H. M. Chan, A. L. Kung, H. Tagami, Y. Nakatani, and D. M. Livingston. 2003. Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science 300:342-344.
-
(2003)
Science
, vol.300
, pp. 342-344
-
-
Grossman, S.R.1
Deato, M.E.2
Brignone, C.3
Chan, H.M.4
Kung, A.L.5
Tagami, H.6
Nakatani, Y.7
Livingston, D.M.8
-
26
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
Gu, W., and R. G. Roeder. 1997. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90:595-606.
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
27
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley, C. B., A. B. Futcher, and C. W. Greider. 1990. Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
28
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick, L. 1965. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37:614-636.
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
29
-
-
2442511752
-
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21 (CIP1), but not p16(INK4a)
-
Herbig, U., W. A. Jobling, B. P. Chen, D. J. Chen, and J. M. Sedivy. 2004. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21 (CIP1), but not p16(INK4a). Mol. Cell 14:501-513.
-
(2004)
Mol. Cell
, vol.14
, pp. 501-513
-
-
Herbig, U.1
Jobling, W.A.2
Chen, B.P.3
Chen, D.J.4
Sedivy, J.M.5
-
30
-
-
2442548716
-
p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels
-
Iyer, N. G., S. F. Chin, H. Ozdag, Y. Daigo, D. E. Hu, M. Cariati, K. Brindle, S. Aparicio, and C. Caldas. 2004. p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels. Proc. Natl. Acad. Sci. USA 101:7386-7391.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7386-7391
-
-
Iyer, N.G.1
Chin, S.F.2
Ozdag, H.3
Daigo, Y.4
Hu, D.E.5
Cariati, M.6
Brindle, K.7
Aparicio, S.8
Caldas, C.9
-
31
-
-
2542584623
-
Promoter-specific p53-dependent histone acetylation following DNA damage
-
Kaeser, M. D., and R. D. Iggo. 2004. Promoter-specific p53-dependent histone acetylation following DNA damage. Oncogene 23:4007-4013.
-
(2004)
Oncogene
, vol.23
, pp. 4007-4013
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
32
-
-
0141731318
-
ING1 represses transcription by direct DNA binding and through effects on p53
-
Kataoka, H., P. Bonnefin, D. Vieyra, X. Feng, Y. Hara, Y. Miura, T. Joh, H. Nakabayashi, H. Vaziri, C. C. Harris, and K. Riabowol. 2003. ING1 represses transcription by direct DNA binding and through effects on p53. Cancer Res. 63:5785-5792.
-
(2003)
Cancer Res.
, vol.63
, pp. 5785-5792
-
-
Kataoka, H.1
Bonnefin, P.2
Vieyra, D.3
Feng, X.4
Hara, Y.5
Miura, Y.6
Joh, T.7
Nakabayashi, H.8
Vaziri, H.9
Harris, C.C.10
Riabowol, K.11
-
33
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
Lambert, P. F., F. Kashanchi, M. F. Radonovich, R. Shiekhattar, and J. N. Brady. 1998. Phosphorylation of p53 serine 15 increases interaction with CBP. J. Biol. Chem. 273:33048-33053.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
34
-
-
1442330508
-
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo
-
Luo, J., M. Li, Y. Tang, M. Laszkowska, R. G. Roeder, and W. Gu. 2004. Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo. Proc. Natl. Acad. Sci. USA 101:2259-2264.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2259-2264
-
-
Luo, J.1
Li, M.2
Tang, Y.3
Laszkowska, M.4
Roeder, R.G.5
Gu, W.6
-
35
-
-
0035859926
-
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53
-
Nagashima, M., M. Shiseki, K. Miura, K. Hagiwara, S. P. Linke, R. Pedeux, X. W. Wang, J. Yokota, K. Riabowol, and C. C. Harris. 2001. DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53. Proc. Natl. Acad. Sci. USA 98:9671-9676.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9671-9676
-
-
Nagashima, M.1
Shiseki, M.2
Miura, K.3
Hagiwara, K.4
Linke, S.P.5
Pedeux, R.6
Wang, X.W.7
Yokota, J.8
Riabowol, K.9
Harris, C.C.10
-
36
-
-
0037461897
-
A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis
-
Nagashima, M., M. Shiseki, R. M. Pedeux, S. Okamura, M. Kitahama-Shiseki, K. Miura, J. Yokota, and C. C. Harris. 2003. A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis. Oncogene 22:343-350.
-
(2003)
Oncogene
, vol.22
, pp. 343-350
-
-
Nagashima, M.1
Shiseki, M.2
Pedeux, R.M.3
Okamura, S.4
Kitahama-Shiseki, M.5
Miura, K.6
Yokota, J.7
Harris, C.C.8
-
37
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita, M., S. Nunez, E. Heard, M. Narita, A. W. Lin, S. A. Hearn, D. L. Spector, G. J. Hannon, and S. W. Lowe. 2003. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113:703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
38
-
-
0029955714
-
The pCL vector system: Rapid production of helper-free, high-titer, recombinant retroviruses
-
Naviaux, R. K., E. Costanzi, M. Haas, and I. M. Verma. 1996. The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J. Virol. 70:5701-5705.
-
(1996)
J. Virol.
, vol.70
, pp. 5701-5705
-
-
Naviaux, R.K.1
Costanzi, E.2
Haas, M.3
Verma, I.M.4
-
39
-
-
0038006271
-
The role of the tumour suppressor p33 ING1b in human neoplasia
-
Nouman, G. S., J. J. Anderson, J. Lunec, and B. Angus. 2003. The role of the tumour suppressor p33 ING1b in human neoplasia. J. Clin. Pathol. 56:491-496.
-
(2003)
J. Clin. Pathol.
, vol.56
, pp. 491-496
-
-
Nouman, G.S.1
Anderson, J.J.2
Lunec, J.3
Angus, B.4
-
40
-
-
0034780285
-
Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex
-
Nourani, A., Y. Doyon, R. T. Utley, S. Allard, W. S. Lane, and J. Cote. 2001. Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex. Mol. Cell. Biol. 21:7629-7640.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7629-7640
-
-
Nourani, A.1
Doyon, Y.2
Utley, R.T.3
Allard, S.4
Lane, W.S.5
Cote, J.6
-
41
-
-
0034644274
-
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
-
Pearson, M., R. Carbone, C. Sebastiani, M. Cioce, M. Fagioli, S. Saito, Y. Higashimoto, E. Appella, S. Minucci, P. P. Pandolfi, and P. G. Pelicci. 2000. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature 406:207-210.
-
(2000)
Nature
, vol.406
, pp. 207-210
-
-
Pearson, M.1
Carbone, R.2
Sebastiani, C.3
Cioce, M.4
Fagioli, M.5
Saito, S.6
Higashimoto, Y.7
Appella, E.8
Minucci, S.9
Pandolfi, P.P.10
Pelicci, P.G.11
-
42
-
-
0035966316
-
Why is p53 acetylated?
-
Prives, C., and J. L. Manley. 2001. Why is p53 acetylated? Cell 107:815-818.
-
(2001)
Cell
, vol.107
, pp. 815-818
-
-
Prives, C.1
Manley, J.L.2
-
43
-
-
1642602686
-
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
-
Sedelnikova, O. A., I. Horikawa, D. B. Zimonjic, N. C. Popescu, W. M. Bonner, and J. C. Barrett. 2004. Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks. Nat. Cell Biol. 6:168-170.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 168-170
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Zimonjic, D.B.3
Popescu, N.C.4
Bonner, W.M.5
Barrett, J.C.6
-
44
-
-
0037416149
-
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
-
Sengupta, S., S. P. Linke, R. Pedeux, Q. Yang, J. Farnsworth, S. H. Garfield, K. Valerie, J. W. Shay, N. A. Ellis, B. Wasylyk, and C. C. Harris. 2003. BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J. 22:1210-1222.
-
(2003)
EMBO J.
, vol.22
, pp. 1210-1222
-
-
Sengupta, S.1
Linke, S.P.2
Pedeux, R.3
Yang, Q.4
Farnsworth, J.5
Garfield, S.H.6
Valerie, K.7
Shay, J.W.8
Ellis, N.A.9
Wasylyk, B.10
Harris, C.C.11
-
45
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano, M., A. W. Lin, M. E. McCurrach, D. Beach, and S. W. Lowe. 1997. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
46
-
-
2342570379
-
Hallmarks of senescence in carcinogenesis and cancer therapy
-
Shay, J. W., and I. B. Roninson. 2004. Hallmarks of senescence in carcinogenesis and cancer therapy. Oncogene 23:2919-2933.
-
(2004)
Oncogene
, vol.23
, pp. 2919-2933
-
-
Shay, J.W.1
Roninson, I.B.2
-
47
-
-
0038520190
-
p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity
-
Shiseki, M., M. Nagashima, R. M. Pedeux, M. Kitahama-Shiseki, K. Miura, S. Okamura, H. Onogi, Y. Higashimoto, E. Appella, J. Yokota, and C. C. Harris. 2003. p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. Cancer Res. 63:2373-2378.
-
(2003)
Cancer Res.
, vol.63
, pp. 2373-2378
-
-
Shiseki, M.1
Nagashima, M.2
Pedeux, R.M.3
Kitahama-Shiseki, M.4
Miura, K.5
Okamura, S.6
Onogi, H.7
Higashimoto, Y.8
Appella, E.9
Yokota, J.10
Harris, C.C.11
-
48
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
Takai, H., A. Smogorzewska, and T. de Lange. 2003. DNA damage foci at dysfunctional telomeres. Curr. Biol. 13:1549-1556.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
De Lange, T.3
-
49
-
-
1342309544
-
No ING1 mutations in human brain tumours but reduced expression in high malignancy grades of astrocytoma
-
Tallen, G., I. Kaiser, S. Krabbe, U. Lass, C. Hartmann, G. Henze, K. Riabowol, and A. von Dehnung. 2004. No ING1 mutations in human brain tumours but reduced expression in high malignancy grades of astrocytoma. Int. J. Cancer 109:476-479.
-
(2004)
Int. J. Cancer
, vol.109
, pp. 476-479
-
-
Tallen, G.1
Kaiser, I.2
Krabbe, S.3
Lass, U.4
Hartmann, C.5
Henze, G.6
Riabowol, K.7
Von Dehnung, A.8
-
50
-
-
0030761351
-
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
-
Vaziri, H., M. D. West, R. C. Allsopp, T. S. Davison, Y. S. Wu, C. H. Arrowsmith, G. G. Poirier, and S. Benchimol. 1997. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J. 16:6018-6033.
-
(1997)
EMBO J.
, vol.16
, pp. 6018-6033
-
-
Vaziri, H.1
West, M.D.2
Allsopp, R.C.3
Davison, T.S.4
Wu, Y.S.5
Arrowsmith, C.H.6
Poirier, G.G.7
Benchimol, S.8
-
51
-
-
19044396946
-
Human ING1 proteins differentially regulate histone acetylation
-
Vieyra, D., R. Loewith, M. Scott, P. Bonnefin, F. M. Boisvert, P. Cheema, S. Pastyryeva, M. Meijer, R. N. Johnston, D. P. Bazett-Jones, S. McMahon, M. D. Cole, D. Young, and K. Riabowol. 2002. Human ING1 proteins differentially regulate histone acetylation. J. Biol. Chem. 277:29832-29839.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29832-29839
-
-
Vieyra, D.1
Loewith, R.2
Scott, M.3
Bonnefin, P.4
Boisvert, F.M.5
Cheema, P.6
Pastyryeva, S.7
Meijer, M.8
Johnston, R.N.9
Bazett-Jones, D.P.10
McMahon, S.11
Cole, M.D.12
Young, D.13
Riabowol, K.14
-
52
-
-
0142258073
-
The tumor-suppressive functions of the human INK4A locus
-
Voorhoeve, P. M., and R. Agami. 2003. The tumor-suppressive functions of the human INK4A locus. Cancer Cell 4:311-319.
-
(2003)
Cancer Cell
, vol.4
, pp. 311-319
-
-
Voorhoeve, P.M.1
Agami, R.2
-
53
-
-
0034114544
-
Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage
-
Webley, K., J. A. Bond, C. J. Jones, J. P. Blaydes, A. Craig, T. Hupp, and D. Wynford-Thomas. 2000. Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage. Mol. Cell. Biol. 20:2803-2808.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2803-2808
-
-
Webley, K.1
Bond, J.A.2
Jones, C.J.3
Blaydes, J.P.4
Craig, A.5
Hupp, T.6
Wynford-Thomas, D.7
-
54
-
-
3042801241
-
Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses
-
Yu, J., I. de Belle, H. Liang, and E. D. Adamson. 2004. Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. Mol. Cell 15:83-94.
-
(2004)
Mol. Cell
, vol.15
, pp. 83-94
-
-
Yu, J.1
De Belle, I.2
Liang, H.3
Adamson, E.D.4
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