메뉴 건너뛰기




Volumn 67, Issue 5, 2007, Pages 2054-2061

Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH INHIBITOR; HOMEODOMAIN PROTEIN; PROTEIN BAX; PROTEIN ING1; PROTEIN P37; PROTEIN P53; UNCLASSIFIED DRUG; ING1 PROTEIN, MOUSE; MDM2 PROTEIN, MOUSE; NUCLEAR PROTEIN; PROTEIN MDM2; SIGNAL PEPTIDE; TUMOR SUPPRESSOR PROTEIN;

EID: 33947194047     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-3558     Document Type: Article
Times cited : (77)

References (38)
  • 1
    • 0029851765 scopus 로고    scopus 로고
    • Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
    • Garkavtsev I, Kazarov A, Gudkov A, Riabowol K. Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation. Nat Genet 1996;14:415-20.
    • (1996) Nat Genet , vol.14 , pp. 415-420
    • Garkavtsev, I.1    Kazarov, A.2    Gudkov, A.3    Riabowol, K.4
  • 2
    • 9744270782 scopus 로고    scopus 로고
    • Biological functions of the ING family tumor suppressors
    • Campos EI, Chin MY, Kuo WH, Li G. Biological functions of the ING family tumor suppressors. Cell Mol Life Sci 2004;61:2597-613.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2597-2613
    • Campos, E.I.1    Chin, M.Y.2    Kuo, W.H.3    Li, G.4
  • 3
    • 11144278644 scopus 로고    scopus 로고
    • Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: Involvement of two silencing domains and effect of Ras
    • Goeman F, Thormeyer D, Abad M, et al. Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras. Mol Cell Biol 2005;25:422-31.
    • (2005) Mol Cell Biol , vol.25 , pp. 422-431
    • Goeman, F.1    Thormeyer, D.2    Abad, M.3
  • 4
    • 1842288569 scopus 로고    scopus 로고
    • A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis
    • Helbing CC, Veillette C, Riabowol K, Johnston RN, Garkavtsev I. A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis. Cancer Res 1997;57:1255-8.
    • (1997) Cancer Res , vol.57 , pp. 1255-1258
    • Helbing, C.C.1    Veillette, C.2    Riabowol, K.3    Johnston, R.N.4    Garkavtsev, I.5
  • 5
    • 0033527542 scopus 로고    scopus 로고
    • Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function
    • Zeremski M, Hill JE, Kwek SS, et al. Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function. J Biol Chem 1999;274:32172-81.
    • (1999) J Biol Chem , vol.274 , pp. 32172-32181
    • Zeremski, M.1    Hill, J.E.2    Kwek, S.S.3
  • 6
    • 0032518510 scopus 로고    scopus 로고
    • The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control
    • Garkavtsev I, Grigorian IA, Ossovskaya VS, et al. The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control. Nature 1998;391:295-8.
    • (1998) Nature , vol.391 , pp. 295-298
    • Garkavtsev, I.1    Grigorian, I.A.2    Ossovskaya, V.S.3
  • 7
    • 0141731318 scopus 로고    scopus 로고
    • ING1 represses transcription by direct DNA binding and through effects on p53
    • Kataoka H, Bonnefin P, Vieyra D, et al. ING1 represses transcription by direct DNA binding and through effects on p53. Cancer Res 2003;63:5785-92.
    • (2003) Cancer Res , vol.63 , pp. 5785-5792
    • Kataoka, H.1    Bonnefin, P.2    Vieyra, D.3
  • 8
    • 0036733697 scopus 로고    scopus 로고
    • The candidate tumor suppressor ING1b can stabilize p53 by disrupting the regulation of p53 by MDM2
    • Leung KM, Po LS, Tsang FC, et al. The candidate tumor suppressor ING1b can stabilize p53 by disrupting the regulation of p53 by MDM2. Cancer Res 2002;62:4890-3.
    • (2002) Cancer Res , vol.62 , pp. 4890-4893
    • Leung, K.M.1    Po, L.S.2    Tsang, F.C.3
  • 9
    • 0036405406 scopus 로고    scopus 로고
    • p33(ING1) enhances UVB-induced apoptosis in melanoma cells
    • Cheung KJ, Li G. p33(ING1) enhances UVB-induced apoptosis in melanoma cells. Exp Cell Res 2002;279:291-8.
    • (2002) Exp Cell Res , vol.279 , pp. 291-298
    • Cheung, K.J.1    Li, G.2
  • 10
    • 0038006271 scopus 로고    scopus 로고
    • The role of the tumour suppressor p33 ING1b in human neoplasia
    • Nouman GS, Anderson JJ, Lunec J, Angus B. The role of the tumour suppressor p33 ING1b in human neoplasia. J Clin Pathol 2003;56:491-6.
    • (2003) J Clin Pathol , vol.56 , pp. 491-496
    • Nouman, G.S.1    Anderson, J.J.2    Lunec, J.3    Angus, B.4
  • 11
    • 32544458369 scopus 로고    scopus 로고
    • Targeted disruption of the mouse ing1 locus results in reduced body size, hypersensitivity to radiation and elevated incidence of lymphomas
    • Kichina JV, Zeremski M, Aris L, et al. Targeted disruption of the mouse ing1 locus results in reduced body size, hypersensitivity to radiation and elevated incidence of lymphomas. Oncogene 2006;25:857-66.
    • (2006) Oncogene , vol.25 , pp. 857-866
    • Kichina, J.V.1    Zeremski, M.2    Aris, L.3
  • 12
    • 0026561121 scopus 로고
    • Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
    • Donehower LA, Harvey M, Slagle BL, et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 1992;356:215-21.
    • (1992) Nature , vol.356 , pp. 215-221
    • Donehower, L.A.1    Harvey, M.2    Slagle, B.L.3
  • 13
    • 0028834902 scopus 로고
    • Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
    • Jones SN, Roe A, Donehower LA, Bradley A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 1995;378:206-8.
    • (1995) Nature , vol.378 , pp. 206-208
    • Jones, S.N.1    Roe, A.2    Donehower, L.A.3    Bradley, A.4
  • 14
    • 84883840386 scopus 로고
    • Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
    • Todaro GJ, Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 1963;17:299-313.
    • (1963) J Cell Biol , vol.17 , pp. 299-313
    • Todaro, G.J.1    Green, H.2
  • 15
    • 0027179908 scopus 로고
    • In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice
    • Harvey M, Sands AT, Weiss RS, et al. In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice. Oncogene 1993;8:2457-67.
    • (1993) Oncogene , vol.8 , pp. 2457-2467
    • Harvey, M.1    Sands, A.T.2    Weiss, R.S.3
  • 16
    • 0036237039 scopus 로고    scopus 로고
    • Oncogenic ras and p53 cooperate to induce cellular senescence
    • Ferbeyre G, de Stanchina E, Lin AW, et al. Oncogenic ras and p53 cooperate to induce cellular senescence. Mol Cell Biol 2002;22:3497-508.
    • (2002) Mol Cell Biol , vol.22 , pp. 3497-3508
    • Ferbeyre, G.1    de Stanchina, E.2    Lin, A.W.3
  • 17
    • 28344454072 scopus 로고    scopus 로고
    • Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development
    • Steinman HA, Hoover KM, Keeler ML, Sands AT, Jones SN. Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development. Oncogene 2005;24:7935-40.
    • (2005) Oncogene , vol.24 , pp. 7935-7940
    • Steinman, H.A.1    Hoover, K.M.2    Keeler, M.L.3    Sands, A.T.4    Jones, S.N.5
  • 20
    • 0030463947 scopus 로고    scopus 로고
    • The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2
    • Jones SN, Sands AT, Hancock AR, et al. The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2. Proc Natl Acad Sci U S A 1996;93:14106-11.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14106-14111
    • Jones, S.N.1    Sands, A.T.2    Hancock, A.R.3
  • 21
    • 0034607702 scopus 로고    scopus 로고
    • Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
    • Tournier C, Hess P, Yang DD, et al. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 2000;288:870-4.
    • (2000) Science , vol.288 , pp. 870-874
    • Tournier, C.1    Hess, P.2    Yang, D.D.3
  • 22
    • 1342343921 scopus 로고    scopus 로고
    • 1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer
    • 1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer. Oncogene 2004;23:973-80.
    • (2004) Oncogene , vol.23 , pp. 973-980
    • Attardi, L.D.1    de Vries, A.2    Jacks, T.3
  • 23
    • 0035555650 scopus 로고    scopus 로고
    • Activation and activities of the p53 tumour suppressor protein. BJC
    • Balint EE, Vousden KH. Activation and activities of the p53 tumour suppressor protein. BJC 2001;85:1813-23.
    • (2001) , vol.85 , pp. 1813-1823
    • Balint, E.E.1    Vousden, K.H.2
  • 24
  • 26
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: Progress and puzzles
    • Lowe SW, Sherr CJ. Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Genet Dev 2003;13:77-83.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 27
    • 0027258466 scopus 로고
    • Thymocyte apoptosis induced by p53-dependent and independent pathways
    • Clarke AR, Purdie CA, Harrison DJ, et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993;362:849-52.
    • (1993) Nature , vol.362 , pp. 849-852
    • Clarke, A.R.1    Purdie, C.A.2    Harrison, D.J.3
  • 28
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993;362:847-9.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 29
    • 10744228800 scopus 로고    scopus 로고
    • Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
    • Jeffers JR, Parganas E, Lee Y, et al. Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell 2003;4:321-8.
    • (2003) Cancer Cell , vol.4 , pp. 321-328
    • Jeffers, J.R.1    Parganas, E.2    Lee, Y.3
  • 30
    • 0842278331 scopus 로고    scopus 로고
    • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    • Chipuk JE, Kuwana T, Bouchier-Hayes L, et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 2004;303:1010-4.
    • (2004) Science , vol.303 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3
  • 31
    • 0344925540 scopus 로고    scopus 로고
    • Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
    • Chipuk JE, Maurer U, Green DR, Schuler M. Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell 2003;4:371-81.
    • (2003) Cancer Cell , vol.4 , pp. 371-381
    • Chipuk, J.E.1    Maurer, U.2    Green, D.R.3    Schuler, M.4
  • 32
    • 29544444195 scopus 로고    scopus 로고
    • ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation
    • Doyon Y, Cayrou C, Ullah M, et al. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Mol Cell 2006;21:51-64.
    • (2006) Mol Cell , vol.21 , pp. 51-64
    • Doyon, Y.1    Cayrou, C.2    Ullah, M.3
  • 33
    • 0036850549 scopus 로고    scopus 로고
    • Different HATS of the ING1 gene family
    • Feng X, Hara Y, Riabowol K. Different HATS of the ING1 gene family. Trends Cell Biol 2002;12:532-8.
    • (2002) Trends Cell Biol , vol.12 , pp. 532-538
    • Feng, X.1    Hara, Y.2    Riabowol, K.3
  • 34
    • 0034780285 scopus 로고    scopus 로고
    • Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex
    • Nourani A, Doyon Y, Utley RT, Allard S, Lane WS, Cote J. Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex. Mol Cell Biol 2001;21:7629-40.
    • (2001) Mol Cell Biol , vol.21 , pp. 7629-7640
    • Nourani, A.1    Doyon, Y.2    Utley, R.T.3    Allard, S.4    Lane, W.S.5    Cote, J.6
  • 35
    • 0142169396 scopus 로고    scopus 로고
    • ING1b decreases cell proliferation through p53-dependent and -independent mechanisms
    • Tsang FC, Po LS, Leung KM, Lau A, Siu WY, Poon RY. ING1b decreases cell proliferation through p53-dependent and -independent mechanisms. FEBS Lett 2003;553:277-85.
    • (2003) FEBS Lett , vol.553 , pp. 277-285
    • Tsang, F.C.1    Po, L.S.2    Leung, K.M.3    Lau, A.4    Siu, W.Y.5    Poon, R.Y.6
  • 36
    • 0034757063 scopus 로고    scopus 로고
    • UV-induced binding of ING1 to PCNA regulates the induction of apoptosis
    • Scott M, Bonnefin P, Vieyra D, et al. UV-induced binding of ING1 to PCNA regulates the induction of apoptosis. J Cell Sci 2001;114:3455-62.
    • (2001) J Cell Sci , vol.114 , pp. 3455-3462
    • Scott, M.1    Bonnefin, P.2    Vieyra, D.3
  • 37
    • 0030449990 scopus 로고    scopus 로고
    • Baxα perturbs T cell development and affects cell cycle entry of T cells
    • Brady HJ, Gil-Gomez G, Kirberg J, Berns AJ. Baxα perturbs T cell development and affects cell cycle entry of T cells. EMBO J 1996;15:6991-7001.
    • (1996) EMBO J , vol.15 , pp. 6991-7001
    • Brady, H.J.1    Gil-Gomez, G.2    Kirberg, J.3    Berns, A.J.4
  • 38
    • 0032535140 scopus 로고    scopus 로고
    • A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis
    • Gil-Gomez G, Berns A, Brady HJ. A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis. EMBO J 1998;17:7209-18.
    • (1998) EMBO J , vol.17 , pp. 7209-7218
    • Gil-Gomez, G.1    Berns, A.2    Brady, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.