-
1
-
-
0033598354
-
P53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: P21WAF1/CIP1 repression in UV induced apoptosis
-
Allan L.A., Fried M. p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells. p21WAF1/CIP1 repression in UV induced apoptosis Oncogene. 18:1999;5403-5412
-
(1999)
Oncogene
, vol.18
, pp. 5403-5412
-
-
Allan, L.A.1
Fried, M.2
-
2
-
-
0028171096
-
Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells
-
Andreassen P.R., Margolis R.L. Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells. J. Cell Biol. 127:1994;789-802
-
(1994)
J. Cell Biol.
, vol.127
, pp. 789-802
-
-
Andreassen, P.R.1
Margolis, R.L.2
-
3
-
-
0031022257
-
Chromosomes with two intact axial cores are induced by G2 checkpoint override: Evidence that DNA decatenation is not required to template the chromosome structure
-
Andreassen P.R., Lacroix F.B., Margolis R.L. Chromosomes with two intact axial cores are induced by G2 checkpoint override. evidence that DNA decatenation is not required to template the chromosome structure J. Cell Biol. 136:1997;29-43
-
(1997)
J. Cell Biol.
, vol.136
, pp. 29-43
-
-
Andreassen, P.R.1
Lacroix, F.B.2
Margolis, R.L.3
-
4
-
-
0035886017
-
Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells
-
Andreassen P.R., Lacroix F.B., Lohez O.D., Margolis R.L. Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells. Cancer Res. 61:2001;7660-7668
-
(2001)
Cancer Res.
, vol.61
, pp. 7660-7668
-
-
Andreassen, P.R.1
Lacroix, F.B.2
Lohez, O.D.3
Margolis, R.L.4
-
5
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F., Dutriaux A., Lengauer C., Waldman T., Zhou S., Brown J.P., Sedivy J.M., Kinzler K.W., Vogelstein B. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science. 282:1998;1497-1501
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
6
-
-
0035063690
-
Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase
-
Campbell M.S., Chan G.K., Yen T.J. Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase. J. Cell Sci. 114:2001;953-963
-
(2001)
J. Cell Sci.
, vol.114
, pp. 953-963
-
-
Campbell, M.S.1
Chan, G.K.2
Yen, T.J.3
-
7
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A., Petersen S., Romanienko P.J., Fernandez-Capetillo O., Chen H.T., Sedelnikova O.A., Reina-San-Martin B., Coppola V., Meffre E., Difilippantonio M.J., et al. Genomic instability in mice lacking histone H2AX. Science. 296:2002;922-927
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
-
8
-
-
0027381810
-
When good enzymes go bad: Conversion of topoisomerase II to a cellular toxin by antineoplastic drugs
-
Corbett A.H., Osheroff N. When good enzymes go bad. conversion of topoisomerase II to a cellular toxin by antineoplastic drugs Chem. Res. Toxicol. 6:1993;585-597
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 585-597
-
-
Corbett, A.H.1
Osheroff, N.2
-
9
-
-
0029315510
-
Tumour suppressors, kinases and clamps: How p53 regulates the cell cycle in response to DNA damage
-
Cox L.S., Lane D.P. Tumour suppressors, kinases and clamps. how p53 regulates the cell cycle in response to DNA damage Bioessays. 17:1995;501-508
-
(1995)
Bioessays
, vol.17
, pp. 501-508
-
-
Cox, L.S.1
Lane, D.P.2
-
11
-
-
0035834003
-
The human decatenation checkpoint
-
Deming P.B., Cistulli C.A., Zhao H., Graves P.R., Piwnica-Worms H., Paules R.S., Downes C.S., Kaufmann W.K. The human decatenation checkpoint. Proc. Natl. Acad. Sci. USA. 98:2001;12044-12049
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12044-12049
-
-
Deming, P.B.1
Cistulli, C.A.2
Zhao, H.3
Graves, P.R.4
Piwnica-Worms, H.5
Paules, R.S.6
Downes, C.S.7
Kaufmann, W.K.8
-
12
-
-
0028139092
-
A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells
-
Downes C.S., Clarke D.J., Mullinger A.M., Gimenez-Abian J.F., Creighton A.M., Johnson R.T. A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells. Nature. 372:1994;467-470
-
(1994)
Nature
, vol.372
, pp. 467-470
-
-
Downes, C.S.1
Clarke, D.J.2
Mullinger, A.M.3
Gimenez-Abian, J.F.4
Creighton, A.M.5
Johnson, R.T.6
-
13
-
-
0029144134
-
Topoisomerase poisons: Harnessing the dark side of enzyme mechanism
-
Froelich-Ammon S.J., Osheroff N. Topoisomerase poisons. harnessing the dark side of enzyme mechanism J. Biol. Chem. 270:1995;21429-21432
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21429-21432
-
-
Froelich-Ammon, S.J.1
Osheroff, N.2
-
14
-
-
0035902920
-
Cohesin cleavage by separase required for anaphase and cytokinesis in human cells
-
Hauf S., Waizenegger I.C., Peters J.M. Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science. 293:2001;1320-1323
-
(2001)
Science
, vol.293
, pp. 1320-1323
-
-
Hauf, S.1
Waizenegger, I.C.2
Peters, J.M.3
-
15
-
-
0033790431
-
Chromosome cohesion, condensation, and separation
-
Hirano T. Chromosome cohesion, condensation, and separation. Annu. Rev. Biochem. 69:2000;115-144
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 115-144
-
-
Hirano, T.1
-
16
-
-
0028240044
-
Coming undone: How to untangle a chromosome
-
Holm C. Coming undone. how to untangle a chromosome Cell. 77:1994;955-957
-
(1994)
Cell
, vol.77
, pp. 955-957
-
-
Holm, C.1
-
17
-
-
0024499711
-
DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage
-
Holm C., Stearns T., Botstein D. DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage. Mol. Cell. Biol. 9:1989;159-168
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 159-168
-
-
Holm, C.1
Stearns, T.2
Botstein, D.3
-
19
-
-
10244251532
-
Identification of a human mitotic checkpoint gene: HsMAD2
-
Li Y., Benezra R. Identification of a human mitotic checkpoint gene. hsMAD2 Science. 274:1996;246-248
-
(1996)
Science
, vol.274
, pp. 246-248
-
-
Li, Y.1
Benezra, R.2
-
20
-
-
0030730855
-
MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity
-
Li Y., Gorbea C., Mahaffey D., Rechsteiner M., Benezra R. MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Proc. Natl. Acad. Sci. USA. 94:1997;12431-12436
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12431-12436
-
-
Li, Y.1
Gorbea, C.2
Mahaffey, D.3
Rechsteiner, M.4
Benezra, R.5
-
21
-
-
0037385783
-
Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis
-
Liu S.T., Hittle J.C., Jablonski S.A., Campbell M.S., Yoda K., Yen T.J. Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. Nat. Cell Biol. 5:2003;341-345
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 341-345
-
-
Liu, S.T.1
Hittle, J.C.2
Jablonski, S.A.3
Campbell, M.S.4
Yoda, K.5
Yen, T.J.6
-
22
-
-
0037183886
-
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2
-
Martin-Lluesma S., Stucke V.M., Nigg E.A. Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science. 297:2002;2267-2270
-
(2002)
Science
, vol.297
, pp. 2267-2270
-
-
Martin-Lluesma, S.1
Stucke, V.M.2
Nigg, E.A.3
-
23
-
-
0031037714
-
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5
-
Meijer L., Borgne A., Mulner O., Chong J.P., Blow J.J., Inagaki N., Inagaki M., Delcros J.G., Moulinoux J.P. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur. J. Biochem. 243:1997;527-536
-
(1997)
Eur. J. Biochem.
, vol.243
, pp. 527-536
-
-
Meijer, L.1
Borgne, A.2
Mulner, O.3
Chong, J.P.4
Blow, J.J.5
Inagaki, N.6
Inagaki, M.7
Delcros, J.G.8
Moulinoux, J.P.9
-
24
-
-
0037195281
-
DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
-
Mikhailov A., Cole R.W., Rieder C.L. DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint. Curr. Biol. 12:2002;1797-1806
-
(2002)
Curr. Biol.
, vol.12
, pp. 1797-1806
-
-
Mikhailov, A.1
Cole, R.W.2
Rieder, C.L.3
-
25
-
-
0037178719
-
Segregating sister genomes: The molecular biology of chromosome separation
-
Nasmyth K. Segregating sister genomes. the molecular biology of chromosome separation Science. 297:2002;559-565
-
(2002)
Science
, vol.297
, pp. 559-565
-
-
Nasmyth, K.1
-
26
-
-
0034717297
-
Splitting the chromosome: Cutting the ties that bind sister chromatids
-
Nasmyth K., Peters J.M., Uhlmann F. Splitting the chromosome. cutting the ties that bind sister chromatids Science. 288:2000;1379-1385
-
(2000)
Science
, vol.288
, pp. 1379-1385
-
-
Nasmyth, K.1
Peters, J.M.2
Uhlmann, F.3
-
27
-
-
0030611095
-
Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
-
Peng C.Y., Graves P.R., Thoma R.S., Wu Z., Shaw A.S., Piwnica-Worms H. Mitotic and G2 checkpoint control. regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216 Science. 277:1997;1501-1505
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
28
-
-
0036284778
-
The anaphase-promoting complex: Proteolysis in mitosis and beyond
-
Peters J.M. The anaphase-promoting complex. proteolysis in mitosis and beyond Mol. Cell. 9:2002;931-943
-
(2002)
Mol. Cell
, vol.9
, pp. 931-943
-
-
Peters, J.M.1
-
29
-
-
0028345406
-
Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp
-
Roca J., Ishida R., Berger J.M., Andoh T., Wang J.C. Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. Proc. Natl. Acad. Sci. USA. 91:1994;1781-1785
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1781-1785
-
-
Roca, J.1
Ishida, R.2
Berger, J.M.3
Andoh, T.4
Wang, J.C.5
-
30
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273:1998;5858-5868
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
31
-
-
0036797033
-
Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension
-
Shannon K.B., Canman J.C., Salmon E.D. Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension. Mol. Biol. Cell. 13:2002;3706-3719
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3706-3719
-
-
Shannon, K.B.1
Canman, J.C.2
Salmon, E.D.3
-
32
-
-
0035836655
-
Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints
-
Skoufias D.A., Andreassen P.R., Lacroix F.B., Wilson L., Margolis R.L. Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints. Proc. Natl. Acad. Sci. USA. 98:2001;4492-4497
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4492-4497
-
-
Skoufias, D.A.1
Andreassen, P.R.2
Lacroix, F.B.3
Wilson, L.4
Margolis, R.L.5
-
33
-
-
0034282252
-
Polo-like kinase-1 is a target of the DNA damage checkpoint
-
Smits V.A., Klompmaker R., Arnaud L., Rijksen G., Nigg E.A., Medema R.H. Polo-like kinase-1 is a target of the DNA damage checkpoint. Nat. Cell Biol. 2:2000;672-676
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 672-676
-
-
Smits, V.A.1
Klompmaker, R.2
Arnaud, L.3
Rijksen, G.4
Nigg, E.A.5
Medema, R.H.6
-
34
-
-
0030687987
-
Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
-
Taylor S.S., McKeon F. Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage. Cell. 89:1997;727-735
-
(1997)
Cell
, vol.89
, pp. 727-735
-
-
Taylor, S.S.1
McKeon, F.2
-
35
-
-
0023651332
-
DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe
-
Uemura T., Ohkura H., Adachi Y., Morino K., Shiozaki K., Yanagida M. DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe. Cell. 50:1987;917-925
-
(1987)
Cell
, vol.50
, pp. 917-925
-
-
Uemura, T.1
Ohkura, H.2
Adachi, Y.3
Morino, K.4
Shiozaki, K.5
Yanagida, M.6
-
36
-
-
1542566719
-
Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores
-
Vagnarelli P., Morrison C., Dodson H., Sonoda E., Takeda S., Earnshaw W.C. Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores. EMBO Rep. 5:2004;167-171
-
(2004)
EMBO Rep.
, vol.5
, pp. 167-171
-
-
Vagnarelli, P.1
Morrison, C.2
Dodson, H.3
Sonoda, E.4
Takeda, S.5
Earnshaw, W.C.6
-
37
-
-
0034721656
-
Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase
-
Waizenegger I.C., Hauf S., Meinke A., Peters J.M. Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell. 103:2000;399-410
-
(2000)
Cell
, vol.103
, pp. 399-410
-
-
Waizenegger, I.C.1
Hauf, S.2
Meinke, A.3
Peters, J.M.4
-
39
-
-
0028849274
-
P21 is necessary for the p53-mediated G1 arrest in human cancer cells
-
Waldman T., Kinzler K.W., Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55:1995;5187-5190
-
(1995)
Cancer Res.
, vol.55
, pp. 5187-5190
-
-
Waldman, T.1
Kinzler, K.W.2
Vogelstein, B.3
-
40
-
-
0037452830
-
The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway
-
Xiao H., Mao Y., Desai S.D., Zhou N., Ting C.Y., Hwang J., Liu L.F. The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway. Proc. Natl. Acad. Sci. USA. 100:2003;3239-3244
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3239-3244
-
-
Xiao, H.1
Mao, Y.2
Desai, S.D.3
Zhou, N.4
Ting, C.Y.5
Hwang, J.6
Liu, L.F.7
-
41
-
-
0037106616
-
Attachment and tension in the spindle assembly checkpoint
-
Zhou J., Yao J., Joshi H.C. Attachment and tension in the spindle assembly checkpoint. J. Cell Sci. 115:2002;3547-3555
-
(2002)
J. Cell Sci.
, vol.115
, pp. 3547-3555
-
-
Zhou, J.1
Yao, J.2
Joshi, H.C.3
-
42
-
-
0035865138
-
Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis
-
Zur A., Brandeis M. Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis. EMBO J. 20:2001;792-801
-
(2001)
EMBO J.
, vol.20
, pp. 792-801
-
-
Zur, A.1
Brandeis, M.2
|