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Volumn 2, Issue 7, 2003, Pages 795-807

Nucleolytic processing of a protein-bound DNA end by the E. coli SbcCD (MR) complex

Author keywords

ABC ATPase; DNA end terminus; Double strand break; Mre11 Rad50; SbcCD; Topoisomerase

Indexed keywords

DOUBLE STRANDED DNA; PROTEIN;

EID: 0037757543     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(03)00063-6     Document Type: Article
Times cited : (86)

References (45)
  • 1
    • 0035695023 scopus 로고    scopus 로고
    • Recombination at double-strand breaks and DNA ends: Conserved mechanisms from phage to humans
    • Cromie G.A., Connelly J.C., Leach D.R.F. Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans. Mol. Cell. 8:2001;1163-1174.
    • (2001) Mol. Cell , vol.8 , pp. 1163-1174
    • Cromie, G.A.1    Connelly, J.C.2    Leach, D.R.F.3
  • 2
    • 0026019344 scopus 로고
    • Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site
    • Sun H., Treco D., Szostak J.W. Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site. Cell. 64:1991;1155-1161.
    • (1991) Cell , vol.64 , pp. 1155-1161
    • Sun, H.1    Treco, D.2    Szostak, J.W.3
  • 3
    • 0026530911 scopus 로고
    • Characterization of double-strand break-induced recombination: Homology requirements and single-stranded DNA formation
    • Sugawara N., Haber J.E. Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol. Cell. Biol. 2:1992;563-575.
    • (1992) Mol. Cell. Biol. , vol.2 , pp. 563-575
    • Sugawara, N.1    Haber, J.E.2
  • 4
    • 0028212415 scopus 로고
    • Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae
    • Ivanov E.L., Sugawara N., White C.I., Fabre F., Haber J.E. Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol. Cell. Biol. 5:1994;3414-3425.
    • (1994) Mol. Cell. Biol. , vol.5 , pp. 3414-3425
    • Ivanov, E.L.1    Sugawara, N.2    White, C.I.3    Fabre, F.4    Haber, J.E.5
  • 5
    • 0029976325 scopus 로고    scopus 로고
    • Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
    • Moore J.K., Haber J.E. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:1996;2164-2173.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2164-2173
    • Moore, J.K.1    Haber, J.E.2
  • 6
    • 0028246091 scopus 로고
    • Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae
    • Schiestl R.H., Zhu J., Petes T.D. Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:1994;4493-5000.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4493-5000
    • Schiestl, R.H.1    Zhu, J.2    Petes, T.D.3
  • 7
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton S.J., Jackson S.P. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17:1998;1819-1828.
    • (1998) EMBO J. , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 8
    • 0032085295 scopus 로고    scopus 로고
    • The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks
    • Paull T.T., Gellert M. The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks. Mol. Cell. 1:1998;969-979.
    • (1998) Mol. Cell , vol.1 , pp. 969-979
    • Paull, T.T.1    Gellert, M.2
  • 9
    • 0034612307 scopus 로고    scopus 로고
    • A mechanistic basis for Mre11-directed DNA joining at microhomologies
    • Paull T.T., Gellert M. A mechanistic basis for Mre11-directed DNA joining at microhomologies. Proc. Natl. Acad. Sci. U.S.A. 97:2000;6409-6414.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 6409-6414
    • Paull, T.T.1    Gellert, M.2
  • 10
    • 0032721091 scopus 로고    scopus 로고
    • The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae
    • Bressan D.A., Baxter B.K., Petrini J.H. The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:1999;7681-7687.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7681-7687
    • Bressan, D.A.1    Baxter, B.K.2    Petrini, J.H.3
  • 11
    • 0035930342 scopus 로고    scopus 로고
    • Promotion of Dnl4-catalysed DNA end joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes
    • Chen L., Trujillo K., Ramos W., Sung P., Tomkinson A.E. Promotion of Dnl4-catalysed DNA end joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol. Cell. 8:2001;1105-1115.
    • (2001) Mol. Cell , vol.8 , pp. 1105-1115
    • Chen, L.1    Trujillo, K.2    Ramos, W.3    Sung, P.4    Tomkinson, A.E.5
  • 13
    • 0036464515 scopus 로고    scopus 로고
    • Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction
    • Huang J., Dynan W.S. Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction. Nucleic Acids Res. 30:2002;667-674.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 667-674
    • Huang, J.1    Dynan, W.S.2
  • 14
    • 0036682830 scopus 로고    scopus 로고
    • Tethering on the brink: The evolutionarily conserved Mre11-Rad50 complex
    • Connelly J.C., Leach D.R. Tethering on the brink: the evolutionarily conserved Mre11-Rad50 complex. Trends Biochem. Sci. 27:2002;410-418.
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 410-418
    • Connelly, J.C.1    Leach, D.R.2
  • 15
    • 0036276388 scopus 로고    scopus 로고
    • The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
    • D'Amours D., Jackson S.P. The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat. Rev. Mol. Cell. Biol. 3:2002;317-327.
    • (2002) Nat. Rev. Mol. Cell. Biol. , vol.3 , pp. 317-327
    • D'Amours, D.1    Jackson, S.P.2
  • 16
    • 0028857690 scopus 로고
    • Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast
    • Sharples G.J., Leach D.R. Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast. Mol. Microbiol. 17:1995;1215-1217.
    • (1995) Mol. Microbiol. , vol.17 , pp. 1215-1217
    • Sharples, G.J.1    Leach, D.R.2
  • 18
    • 0030089480 scopus 로고    scopus 로고
    • The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination
    • Connelly J.C., Leach D.R. The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination. Genes Cells. 1:1996;285-291.
    • (1996) Genes Cells , vol.1 , pp. 285-291
    • Connelly, J.C.1    Leach, D.R.2
  • 19
    • 0032476658 scopus 로고    scopus 로고
    • Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination
    • Furuse M., Nagase Y., Tsubouchi H., Murakami-Murofushi K., Shibata T., Ohta K. Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J. 17:1998;6412-6425.
    • (1998) EMBO J. , vol.17 , pp. 6412-6425
    • Furuse, M.1    Nagase, Y.2    Tsubouchi, H.3    Murakami-Murofushi, K.4    Shibata, T.5    Ohta, K.6
  • 20
    • 0030756165 scopus 로고    scopus 로고
    • Overexpression, purification, and characterisation of the SbcCD protein from Escherichia coli
    • Connelly J.C., de Leau E.S., Okely E.A., Leach D.R.F. Overexpression, purification, and characterisation of the SbcCD protein from Escherichia coli. J. Biol. Chem. 272:1997;19819-19826.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19819-19826
    • Connelly, J.C.1    De Leau, E.S.2    Okely, E.A.3    Leach, D.R.F.4
  • 21
    • 0032076248 scopus 로고    scopus 로고
    • The hMre11/Rad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
    • Carney J.P., Maser R.S., Olivares H., Davis E.M., Le Beau M., Yates J.R. III, Hays L., Morgan W., Petrini J.H. The hMre11/Rad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell. 93:1998;477-486.
    • (1998) Cell , vol.93 , pp. 477-486
    • Carney, J.P.1    Maser, R.S.2    Olivares, H.3    Davis, E.M.4    Le Beau, M.5    Yates J.R. III6    Hays, L.7    Morgan, W.8    Petrini, J.H.9
  • 22
    • 0035906860 scopus 로고    scopus 로고
    • Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
    • Hopfner K.P., Karcher A., Craig L., Woo T.W., Carney J.P., Tainer J.A. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell. 105:2001;473-485.
    • (2001) Cell , vol.105 , pp. 473-485
    • Hopfner, K.P.1    Karcher, A.2    Craig, L.3    Woo, T.W.4    Carney, J.P.5    Tainer, J.A.6
  • 23
    • 0032493294 scopus 로고    scopus 로고
    • The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA
    • Connelly J.C., Kirkham L.A., Leach D.R. The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA. Proc. Natl. Acad. Sci. U.S.A. 95:1998;7969-7974.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 7969-7974
    • Connelly, J.C.1    Kirkham, L.A.2    Leach, D.R.3
  • 24
    • 0033557344 scopus 로고    scopus 로고
    • DNA cleavage and degradation by the SbcCD protein complex from Escherichia coli
    • Connelly J.C., de Leau E.S., Leach D.R.F. DNA cleavage and degradation by the SbcCD protein complex from Escherichia coli. Nucleic Acids Res. 27:1999;1039-11046.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1039-11046
    • Connelly, J.C.1    De Leau, E.S.2    Leach, D.R.F.3
  • 25
    • 0033563229 scopus 로고    scopus 로고
    • Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex
    • Paull T.T., Gellert M. Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev. 13:1999;1276-1288.
    • (1999) Genes Dev. , vol.13 , pp. 1276-1288
    • Paull, T.T.1    Gellert, M.2
  • 26
    • 0033759543 scopus 로고    scopus 로고
    • Mre11 and Rad50 from Pyrococcus furiosus: Cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine
    • Hopfner K.P., Karcher A., Shin D., Fairley C., Tainer J.A., Carney J.P. Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine. J. Bacteriol. 182:2000;6036-6041.
    • (2000) J. Bacteriol. , vol.182 , pp. 6036-6041
    • Hopfner, K.P.1    Karcher, A.2    Shin, D.3    Fairley, C.4    Tainer, J.A.5    Carney, J.P.6
  • 27
    • 0035929667 scopus 로고    scopus 로고
    • DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50/Mre11 complex
    • Trujillo K.M., Sung P. DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50/Mre11 complex. J. Biol. Chem. 276:2001;35458-35464.
    • (2001) J. Biol. Chem. , vol.276 , pp. 35458-35464
    • Trujillo, K.M.1    Sung, P.2
  • 28
    • 0030714064 scopus 로고    scopus 로고
    • Repair by recombination of DNA containing a palindromic sequence
    • Leach D.R., Okely E.A., Pinder D.J. Repair by recombination of DNA containing a palindromic sequence. Mol. Microbiol. 26:1997;597-606.
    • (1997) Mol. Microbiol. , vol.26 , pp. 597-606
    • Leach, D.R.1    Okely, E.A.2    Pinder, D.J.3
  • 29
    • 0036265864 scopus 로고    scopus 로고
    • A 160-bp palindrome is a Rad50/Rad32-dependent mitotic recombination hotspot in Schizosaccharomyces pombe
    • Farah J.A., Hartsuiker E., Mizuno K., Ohta K., Smith G.R. A 160-bp palindrome is a Rad50/Rad32-dependent mitotic recombination hotspot in Schizosaccharomyces pombe. Genetics. 161:2002;461-468.
    • (2002) Genetics , vol.161 , pp. 461-468
    • Farah, J.A.1    Hartsuiker, E.2    Mizuno, K.3    Ohta, K.4    Smith, G.R.5
  • 30
    • 0037169325 scopus 로고    scopus 로고
    • The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
    • Lobachev K.S., Gordenin D.A., Resnick M.A. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell. 108:2002;183-193.
    • (2002) Cell , vol.108 , pp. 183-193
    • Lobachev, K.S.1    Gordenin, D.A.2    Resnick, M.A.3
  • 31
    • 0034192363 scopus 로고    scopus 로고
    • Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres
    • Lombard D.B., Guarente L. Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res. 60:2000;2331-2334.
    • (2000) Cancer Res. , vol.60 , pp. 2331-2334
    • Lombard, D.B.1    Guarente, L.2
  • 32
    • 0342561644 scopus 로고    scopus 로고
    • Cell-cycle-regulated association of RAD50/MRE11/NBS1 with trf2 and human telomeres
    • Zhu X.D., Kuster B., Mann M., Petrini J.H., Lange T. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with trf2 and human telomeres. Nat. Genet. 25:2000;347-352.
    • (2000) Nat. Genet. , vol.25 , pp. 347-352
    • Zhu, X.D.1    Kuster, B.2    Mann, M.3    Petrini, J.H.4    Lange, T.5
  • 33
    • 0037130170 scopus 로고    scopus 로고
    • Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
    • Stracker T.H., Carson C.T., Weitzman M.D. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature. 418:2002;348-352.
    • (2002) Nature , vol.418 , pp. 348-352
    • Stracker, T.H.1    Carson, C.T.2    Weitzman, M.D.3
  • 34
    • 0030011434 scopus 로고    scopus 로고
    • Role of recombinational repair in sensitivity to an antitumour agent that inhibits bacteriophage T4 type II DNA topoisomerase
    • Neece S.H., Carles-Kinch K., Tomso D.J., Kreuzer K.N. Role of recombinational repair in sensitivity to an antitumour agent that inhibits bacteriophage T4 type II DNA topoisomerase. Mol. Microbiol. 20:1996;1145-1154.
    • (1996) Mol. Microbiol. , vol.20 , pp. 1145-1154
    • Neece, S.H.1    Carles-Kinch, K.2    Tomso, D.J.3    Kreuzer, K.N.4
  • 35
    • 0029888199 scopus 로고    scopus 로고
    • Bacteriophage T4 mutants hypersensitive to an antitumor agent that induces topoisomerase-DNA cleavage complexes
    • Woodworth D.L., Kreuzer K.N. Bacteriophage T4 mutants hypersensitive to an antitumor agent that induces topoisomerase-DNA cleavage complexes. Genetics. 143:1996;1081-1090.
    • (1996) Genetics , vol.143 , pp. 1081-1090
    • Woodworth, D.L.1    Kreuzer, K.N.2
  • 36
    • 0036211833 scopus 로고    scopus 로고
    • Induction of biphasic DNA double-strand breaks and activation of multiple repair protein complexes by DNA topoisomerase I drug 7-ethyl-10-hydroxy-camptothecin
    • Wu J., Yin M., Hapke G., Toth K., Rustum Y.M. Induction of biphasic DNA double-strand breaks and activation of multiple repair protein complexes by DNA topoisomerase I drug 7-ethyl-10-hydroxy-camptothecin. Mol. Pharmacol. 61:2002;742-748.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 742-748
    • Wu, J.1    Yin, M.2    Hapke, G.3    Toth, K.4    Rustum, Y.M.5
  • 37
    • 0024669753 scopus 로고
    • The yeast RAD50 gene encodes a predicted 153-kDa protein containing a purine nucleotide-binding domain and two large heptad-repeat regions
    • Alani E., Subbiah S., Kleckner N. The yeast RAD50 gene encodes a predicted 153-kDa protein containing a purine nucleotide-binding domain and two large heptad-repeat regions. Genetics. 122:1989;47-57.
    • (1989) Genetics , vol.122 , pp. 47-57
    • Alani, E.1    Subbiah, S.2    Kleckner, N.3
  • 38
    • 0030893115 scopus 로고    scopus 로고
    • Meiosis-specific DNA double-strand breaks are catalysed by Spo11, a member of a widely conserved protein family
    • Keeney S., Giroux C.N., Kleckner N. Meiosis-specific DNA double-strand breaks are catalysed by Spo11, a member of a widely conserved protein family. Cell. 88:1997;375-384.
    • (1997) Cell , vol.88 , pp. 375-384
    • Keeney, S.1    Giroux, C.N.2    Kleckner, N.3
  • 40
    • 0018874853 scopus 로고
    • Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion
    • Shalloway D., Kleinberger T., Livingston D.M. Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion. Cell. 20:1980;411-422.
    • (1980) Cell , vol.20 , pp. 411-422
    • Shalloway, D.1    Kleinberger, T.2    Livingston, D.M.3
  • 42
    • 0025334351 scopus 로고
    • Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapses and recombination
    • Alani E., Padmore R., Kleckner N. Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapses and recombination. Cell. 61:1990;419-436.
    • (1990) Cell , vol.61 , pp. 419-436
    • Alani, E.1    Padmore, R.2    Kleckner, N.3
  • 44
    • 0034437341 scopus 로고    scopus 로고
    • Envisioning the fourth dimension of the genetic code: The structural biology of macromolecular recognition and conformational switching in DNA repair
    • Hopfner K.P., Parikh S.S., Tainer J.A. Envisioning the fourth dimension of the genetic code: the structural biology of macromolecular recognition and conformational switching in DNA repair. Cold Spring Harb. Symp. Quant. Biol. 65:2000;113-126.
    • (2000) Cold Spring Harb. Symp. Quant. Biol. , vol.65 , pp. 113-126
    • Hopfner, K.P.1    Parikh, S.S.2    Tainer, J.A.3
  • 45
    • 0033522512 scopus 로고    scopus 로고
    • DNA translocation blockage, a general mechanism of cleavage site selection by type I restriction enzymes
    • Janscak P., MacWilliams M.P., Sandmeier U., Nagaraja V., Bickle T.A. DNA translocation blockage, a general mechanism of cleavage site selection by type I restriction enzymes. EMBO J. 18:1999;2638-2647.
    • (1999) EMBO J. , vol.18 , pp. 2638-2647
    • Janscak, P.1    MacWilliams, M.P.2    Sandmeier, U.3    Nagaraja, V.4    Bickle, T.A.5


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