Permeability - In vitro assays for assessing drug transporter activity

Current Drug Metabolism

Volumn 9, Issue 9, 2008, Pages 911-920

  Jin, Hong ^a   Di, Li ^a  

^a PFIZER INC   (United States)

Author keywords

ABC transport; Drug drug interaction; Efflux; In vitro assay; Induction; Permeability; Solute carrier transporter; Uptake

Indexed keywords

ACICLOVIR; ADENOSINE TRIPHOSPHATASE; AMANTADINE; AMOXICILLIN; AMPICILLIN; CIMETIDINE; CISPLATIN; DAUNORUBICIN; DIGOXIN; ETOPOSIDE; INDINAVIR; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 4; OCTAMER TRANSCRIPTION FACTOR 1; OCTAMER TRANSCRIPTION FACTOR 2; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; PACLITAXEL; PRAVASTATIN; QUINIDINE; RIFAMPICIN; ROSUVASTATIN; SALAZOSULFAPYRIDINE; TOPOTECAN; UNINDEXED DRUG; VALACICLOVIR; VERAPAMIL; VINBLASTINE; VINCRISTINE; CARRIER PROTEIN; DRUG; GLYCOPROTEIN P;

CELL ASSAY; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG PENETRATION; DRUG TRANSPORT; ELECTRIC RESISTANCE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SPECIFICITY; HUMAN; IN VITRO STUDY; NONHUMAN; PASSIVE TRANSPORT; PROTEIN FUNCTION; REVIEW; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE; CULTURE TECHNIQUE; GENETICS; LIVER CELL; METABOLISM; PERMEABILITY;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CARRIER PROTEINS; CELL CULTURE TECHNIQUES; CELL LINE; CELL MEMBRANE; HEPATOCYTES; HUMANS; P-GLYCOPROTEIN; PERMEABILITY; PHARMACEUTICAL PREPARATIONS;

EID: 60749089233     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920008786485056     Document Type: Review

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