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Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1361, Issue 2, 1997, Pages 159-168

Structure-activity relationships of P-glycoprotein interacting drugs: Kinetic characterization of their effects on ATPase activity

(4) Litman, Thomas a,b Zeuthen, Thomas b Skovsgaard, Torben a Stein, Wilfred D c

a UNIVERSITY OF COPENHAGEN (Denmark)

b UNIVERSITY OF COPENHAGEN (Denmark)

c HEBREW UNIVERSITY OF JERUSALEM (Israel)

Author keywords

ATPase; Kinetic parameter; Multidrug resistance; P glycoprotein; Structure activity relationship

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMIODARONE; CALMODULIN INHIBITOR; CHLORPROMAZINE; COLCHICINE; CYCLOSPORIN A; DIPYRIDAMOLE; FLUPHENAZINE; FUSIDATE SODIUM; GLYCOPROTEIN P; GRAMICIDIN S; MEFLOQUINE; METHOTREXATE; PIMOZIDE; PROGESTERONE; PROMETHAZINE; PROPAFENONE; QUINIDINE; RESERPINE; SPIRONOLACTONE; STEROID; TAMOXIFEN; TERFENADINE; TRIFLUOPERAZINE; TRIFLUPROMAZINE; VALINOMYCIN; VALSPODAR; VERAPAMIL;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL LINE; CELL MEMBRANE; CHO CELL; CONTROLLED STUDY; EHRLICH ASCITES TUMOR CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; MULTIDRUG RESISTANCE; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTHRACYCLINES; CHO CELLS; CRICETINAE; DRUG RESISTANCE, MULTIPLE; ENZYME ACTIVATION; KINETICS; MICROSOMES; P-GLYCOPROTEIN; PEPTIDES; PHARMACEUTICAL PREPARATIONS; PHENOTHIAZINES; QUINOLINES; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; VINCA ALKALOIDS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0030791978 PISSN: 09254439 EISSN: None Source Type: Journal
DOI: 10.1016/S0925-4439(97)00026-4 Document Type: Article

Times cited : (179)

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