Effect of probenecid on fluorescein transport in the central nervous system using in vitro and in vivo models

Pharmaceutical Research

Volumn 18, Issue 11, 2001, Pages 1542-1549

  Sun, Haiying ^a   Miller, Donald W ^a   Elmquist, William F ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Blood brain barrier; Blood CSF barrier; Fluorescein; Microdialysis; Multidrug resistance associated protein; Probenecid

Indexed keywords

ANION; CARRIER PROTEIN; FLUORESCEIN; FLUORESCENT DYE; GLYCOPROTEIN P; INDOMETACIN; LY 329146; MULTIDRUG RESISTANCE PROTEIN; PROBENECID; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; ZOSUQUIDAR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG TRANSPORT; EXTRACELLULAR FLUID; IN VITRO STUDY; IN VIVO STUDY; MICRODIALYSIS; MODEL; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ALGORITHMS; ANIMALS; BLOOD-BRAIN BARRIER; CALIBRATION; CAPILLARIES; CATTLE; CELL SEPARATION; CENTRAL NERVOUS SYSTEM; ENDOTHELIUM, VASCULAR; FLUORESCEIN; FLUORESCENT DYES; MICRODIALYSIS; MODELS, BIOLOGICAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROBENECID; RATS; URICOSURIC AGENTS;

EID: 0034747783     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013074229576     Document Type: Article

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