메뉴 건너뛰기




Volumn 32, Issue 6, 2008, Pages 1010-1032

Magnificent seven: Roles of G protein-coupled receptors in extracellular sensing in fungi

Author keywords

Extracellular sensing; Fungus; G protein; G protein coupled receptor

Indexed keywords

AMINO ACID; FATTY ACID; G PROTEIN COUPLED RECEPTOR; GLUCOSE; MEMBRANE PROTEIN; OPSIN; PHEROMONE; PROTEIN STM1; UNCLASSIFIED DRUG;

EID: 53749087941     PISSN: 01686445     EISSN: 15746976     Source Type: Journal    
DOI: 10.1111/j.1574-6976.2008.00131.x     Document Type: Review
Times cited : (153)

References (212)
  • 2
    • 3342900058 scopus 로고    scopus 로고
    • Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes
    • Andersson J, Simpson DM, Qi M, Wang Y Elion EA (2004) Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J 23 : 2564 2576.
    • (2004) EMBO J , vol.23 , pp. 2564-2576
    • Andersson, J.1    Simpson, D.M.2    Qi, M.3    Wang, Y.4    Elion, E.A.5
  • 3
    • 0032492722 scopus 로고    scopus 로고
    • Sst2 is a GTPase-activating protein for Gpa1: Purification and characterization of a cognate RGS-Galpha protein pair in yeast
    • Apanovitch DM, Slep KC, Sigler PB Dohlman HG (1998) Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast. Biochemistry 37 : 4815 4822.
    • (1998) Biochemistry , vol.37 , pp. 4815-4822
    • Apanovitch, D.M.1    Slep, K.C.2    Sigler, P.B.3    Dohlman, H.G.4
  • 4
    • 0028174033 scopus 로고
    • Fingerprinting G-protein-coupled receptors
    • Attwood TK Findlay JB (1994) Fingerprinting G-protein-coupled receptors. Protein Eng 7 : 195 203.
    • (1994) Protein Eng , vol.7 , pp. 195-203
    • Attwood, T.K.1    Findlay, J.B.2
  • 6
    • 0242572132 scopus 로고    scopus 로고
    • Dimerization of G-protein-coupled receptors: Roles in signal transduction
    • Bai M (2004) Dimerization of G-protein-coupled receptors: roles in signal transduction. Cell Signal 16 : 175 186.
    • (2004) Cell Signal , vol.16 , pp. 175-186
    • Bai, M.1
  • 8
    • 4544300880 scopus 로고    scopus 로고
    • A walk-through of the yeast mating pheromone response pathway
    • Bardwell L (2004) A walk-through of the yeast mating pheromone response pathway. Peptides 25 : 1465 1476.
    • (2004) Peptides , vol.25 , pp. 1465-1476
    • Bardwell, L.1
  • 9
    • 0028556727 scopus 로고
    • Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae
    • Bardwell L, Cook JG, Inouye CJ Thorner J (1994) Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Dev Biol 166 : 363 379.
    • (1994) Dev Biol , vol.166 , pp. 363-379
    • Bardwell, L.1    Cook, J.G.2    Inouye, C.J.3    Thorner, J.4
  • 10
    • 0037442660 scopus 로고    scopus 로고
    • Krh1p and Krh2p act downstream of the Gpa2p G(alpha) subunit to negatively regulate haploid invasive growth
    • Batlle M, Lu A, Green DA, Xue Y Hirsch JP (2003) Krh1p and Krh2p act downstream of the Gpa2p G(alpha) subunit to negatively regulate haploid invasive growth. J Cell Sci 116 : 701 710.
    • (2003) J Cell Sci , vol.116 , pp. 701-710
    • Batlle, M.1    Lu, A.2    Green, D.A.3    Xue, Y.4    Hirsch, J.P.5
  • 11
    • 27144497790 scopus 로고    scopus 로고
    • Mating in Candida albicans and the search for a sexual cycle
    • Bennett RJ Johnson AD (2005) Mating in Candida albicans and the search for a sexual cycle. Annu Rev Microbiol 59 : 233 255.
    • (2005) Annu Rev Microbiol , vol.59 , pp. 233-255
    • Bennett, R.J.1    Johnson, A.D.2
  • 13
    • 0033529279 scopus 로고    scopus 로고
    • The nop-1 gene of Neurospora crassa encodes a seven transmembrane helix retinal-binding protein homologous to archaeal rhodopsins
    • Bieszke JA, Braun EL, Bean LE, Kang S, Natvig DO Borkovich KA (1999a) The nop-1 gene of Neurospora crassa encodes a seven transmembrane helix retinal-binding protein homologous to archaeal rhodopsins. Proc Natl Acad Sci USA 96 : 8034 8039.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8034-8039
    • Bieszke, J.A.1    Braun, E.L.2    Bean, L.E.3    Kang, S.4    Natvig, D.O.5    Borkovich, K.A.6
  • 14
    • 0033607149 scopus 로고    scopus 로고
    • A eukaryotic protein, NOP-1, binds retinal to form an archaeal rhodopsin-like photochemically reactive pigment
    • Bieszke JA, Spudich EN, Scott KL, Borkovich KA Spudich JL (1999b) A eukaryotic protein, NOP-1, binds retinal to form an archaeal rhodopsin-like photochemically reactive pigment. Biochemistry 38 : 14138 14145.
    • (1999) Biochemistry , vol.38 , pp. 14138-14145
    • Bieszke, J.A.1    Spudich, E.N.2    Scott, K.L.3    Borkovich, K.A.4    Spudich, J.L.5
  • 15
    • 34548329143 scopus 로고    scopus 로고
    • The fungal opsin gene nop-1 is negatively-regulated by a component of the blue light sensing pathway and influences conidiation-specific gene expression in Neurospora crassa
    • Bieszke JA, Li L Borkovich KA (2007) The fungal opsin gene nop-1 is negatively-regulated by a component of the blue light sensing pathway and influences conidiation-specific gene expression in Neurospora crassa. Curr Genet 52 : 149 157.
    • (2007) Curr Genet , vol.52 , pp. 149-157
    • Bieszke, J.A.1    Li, L.2    Borkovich, K.A.3
  • 16
    • 33847781275 scopus 로고    scopus 로고
    • Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling
    • Blumer JB, Smrcka AV Lanier SM (2007) Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling. Pharmacol Ther 113 : 488 506.
    • (2007) Pharmacol Ther , vol.113 , pp. 488-506
    • Blumer, J.B.1    Smrcka, A.V.2    Lanier, S.M.3
  • 17
    • 0026500677 scopus 로고
    • The a mating type locus of U. maydis specifies cell signaling components
    • Bolker M, Urban M Kahmann R (1992) The a mating type locus of U. maydis specifies cell signaling components. Cell 68 : 441 450.
    • (1992) Cell , vol.68 , pp. 441-450
    • Bolker, M.1    Urban, M.2    Kahmann, R.3
  • 18
    • 12144287318 scopus 로고    scopus 로고
    • Lessons from the genome sequence of Neurospora crassa: Tracing the path from genomic blueprint to multicellular organism
    • Borkovich KA, Alex LA, Yarden O et al 2004) Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol Mol Biol Rev 68 : 1 108.
    • (2004) Microbiol Mol Biol Rev , vol.68 , pp. 1-108
    • Borkovich, K.A.1    Alex, L.A.2    Yarden, O.3    Al, E.4
  • 19
    • 33748920925 scopus 로고    scopus 로고
    • The structure and synthesis of the fungal cell wall
    • Bowman SM Free SJ (2006) The structure and synthesis of the fungal cell wall. Bioessays 28 : 799 808.
    • (2006) Bioessays , vol.28 , pp. 799-808
    • Bowman, S.M.1    Free, S.J.2
  • 20
    • 0034650702 scopus 로고    scopus 로고
    • Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha-subunit chimeras
    • Brown AJ, Dyos SL, Whiteway MS et al 2000) Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha-subunit chimeras. Yeast 16 : 11 22.
    • (2000) Yeast , vol.16 , pp. 11-22
    • Brown, A.J.1    Dyos, S.L.2    Whiteway, M.S.3    Al, E.4
  • 21
    • 0038363378 scopus 로고    scopus 로고
    • The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
    • Brown AJ, Goldsworthy SM, Barnes AA et al 2003) The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278 : 11312 11319.
    • (2003) J Biol Chem , vol.278 , pp. 11312-11319
    • Brown, A.J.1    Goldsworthy, S.M.2    Barnes, A.A.3    Al, E.4
  • 22
    • 11844275233 scopus 로고    scopus 로고
    • A family of fatty acid binding receptors
    • Brown AJ, Jupe S Briscoe CP (2005) A family of fatty acid binding receptors. DNA Cell Biol 24 : 54 61.
    • (2005) DNA Cell Biol , vol.24 , pp. 54-61
    • Brown, A.J.1    Jupe, S.2    Briscoe, C.P.3
  • 23
  • 24
    • 0022422406 scopus 로고
    • The yeast alpha-factor receptor: Structural properties deduced from the sequence of the STE2 gene
    • Burkholder AC Hartwell LH (1985) The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene. Nucleic Acids Res 13 : 8463 8475.
    • (1985) Nucleic Acids Res , vol.13 , pp. 8463-8475
    • Burkholder, A.C.1    Hartwell, L.H.2
  • 25
    • 40149090884 scopus 로고    scopus 로고
    • The evolution of MAT: The ascomycetes
    • Heitman, J., Kronstad, J.W., Taylor, J.W. Casselton, L.A., eds), pp. ASM Press, Washington, DC.
    • Butler G (2007) The evolution of MAT: the ascomycetes. Sex in Fungi (Heitman J, Kronstad JW, Taylor JW Casselton LA, eds), pp. 3 18. ASM Press, Washington, DC.
    • (2007) Sex in Fungi , pp. 3-18
    • Butler, G.1
  • 27
    • 22744437852 scopus 로고    scopus 로고
    • Candida glabrata Ste11 is involved in adaptation to hypertonic stress, maintenance of wild-type levels of filamentation and plays a role in virulence
    • Calcagno AM, Bignell E, Rogers TR, Jones MD, Muhlschlegel FA Haynes K (2005) Candida glabrata Ste11 is involved in adaptation to hypertonic stress, maintenance of wild-type levels of filamentation and plays a role in virulence. Med Mycol 43 : 355 364.
    • (2005) Med Mycol , vol.43 , pp. 355-364
    • Calcagno, A.M.1    Bignell, E.2    Rogers, T.R.3    Jones, M.D.4    Muhlschlegel, F.A.5    Haynes, K.6
  • 28
    • 85047686020 scopus 로고    scopus 로고
    • Mate recognition in fungi
    • Casselton LA (2002) Mate recognition in fungi. Heredity 88 : 142 147.
    • (2002) Heredity , vol.88 , pp. 142-147
    • Casselton, L.A.1
  • 29
    • 0031888793 scopus 로고    scopus 로고
    • Molecular genetics of mating recognition in basidiomycete fungi
    • Casselton LA Olesnicky NS (1998) Molecular genetics of mating recognition in basidiomycete fungi. Microbiol Mol Biol Rev 62 : 55 70.
    • (1998) Microbiol Mol Biol Rev , vol.62 , pp. 55-70
    • Casselton, L.A.1    Olesnicky, N.S.2
  • 30
    • 0021193681 scopus 로고
    • The mammalian beta 2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system
    • Cerione RA, Codina J, Benovic JL, Lefkowitz RJ, Birnbaumer L Caron MG (1984) The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system. Biochemistry 23 : 4519 4525.
    • (1984) Biochemistry , vol.23 , pp. 4519-4525
    • Cerione, R.A.1    Codina, J.2    Benovic, J.L.3    Lefkowitz, R.J.4    Birnbaumer, L.5    Caron, M.G.6
  • 31
    • 0021873142 scopus 로고
    • Molecular cloning and characterization of the STE7 and STE11 genes of Saccharomyces cerevisiae
    • Chaleff DT Tatchell K (1985) Molecular cloning and characterization of the STE7 and STE11 genes of Saccharomyces cerevisiae. Mol Cell Biol 5 : 1878 1886.
    • (1985) Mol Cell Biol , vol.5 , pp. 1878-1886
    • Chaleff, D.T.1    Tatchell, K.2
  • 33
    • 0042825487 scopus 로고    scopus 로고
    • Importance of a developmentally regulated pheromone receptor of Cryptococcus neoformans for virulence
    • Chang YC, Miller GF Kwon-Chung KJ (2003) Importance of a developmentally regulated pheromone receptor of Cryptococcus neoformans for virulence. Infect Immun 71 : 4953 4960.
    • (2003) Infect Immun , vol.71 , pp. 4953-4960
    • Chang, Y.C.1    Miller, G.F.2    Kwon-Chung, K.J.3
  • 34
    • 32944462411 scopus 로고    scopus 로고
    • Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae
    • Chasse SA, Flanary P, Parnell SC, Hao N, Cha JY, Siderovski DP Dohlman HG (2006) Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae. Eukaryot Cell 5 : 330 346.
    • (2006) Eukaryot Cell , vol.5 , pp. 330-346
    • Chasse, S.A.1    Flanary, P.2    Parnell, S.C.3    Hao, N.4    Cha, J.Y.5    Siderovski, D.P.6    Dohlman, H.G.7
  • 36
    • 0031055072 scopus 로고    scopus 로고
    • Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor
    • Chen P, Sapperstein SK, Choi JD Michaelis S (1997) Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor. J Cell Biol 136 : 251 269.
    • (1997) J Cell Biol , vol.136 , pp. 251-269
    • Chen, P.1    Sapperstein, S.K.2    Choi, J.D.3    Michaelis, S.4
  • 37
    • 0029656276 scopus 로고    scopus 로고
    • Regulation of the G-protein-coupled alpha-factor pheromone receptor by phosphorylation
    • Chen Q Konopka JB (1996) Regulation of the G-protein-coupled alpha-factor pheromone receptor by phosphorylation. Mol Cell Biol 16 : 247 257.
    • (1996) Mol Cell Biol , vol.16 , pp. 247-257
    • Chen, Q.1    Konopka, J.B.2
  • 38
    • 0035955625 scopus 로고    scopus 로고
    • Isolation of a novel gene from Schizosaccharomyces pombe: Stm1+ encoding a seven-transmembrane loop protein that may couple with the heterotrimeric Galpha 2 protein, Gpa2
    • Chung KS, Won M, Lee SB, Jang YJ, Hoe KL, Kim DU, Lee JW, Kim KW Yoo HS (2001) Isolation of a novel gene from Schizosaccharomyces pombe: stm1+ encoding a seven-transmembrane loop protein that may couple with the heterotrimeric Galpha 2 protein, Gpa2. J Biol Chem 276 : 40190 40201.
    • (2001) J Biol Chem , vol.276 , pp. 40190-40201
    • Chung, K.S.1    Won, M.2    Lee, S.B.3    Jang, Y.J.4    Hoe, K.L.5    Kim, D.U.6    Lee, J.W.7    Kim, K.W.8    Yoo, H.S.9
  • 39
    • 0037296932 scopus 로고    scopus 로고
    • Functional over-expression of the Stm1 protein, a G-protein-coupled receptor, in Schizosaccharomyces pombe
    • Chung KS, Kim DU, Ryoo SW et al 2003) Functional over-expression of the Stm1 protein, a G-protein-coupled receptor, in Schizosaccharomyces pombe. Biotechnol Lett 25 : 267 272.
    • (2003) Biotechnol Lett , vol.25 , pp. 267-272
    • Chung, K.S.1    Kim, D.U.2    Ryoo, S.W.3    Al, E.4
  • 40
    • 34147142000 scopus 로고    scopus 로고
    • Yeast-based screening to identify modulators of G-protein signaling using uncontrolled cell division cycle by overexpression of Stm1
    • Chung KS, Won M, Lee JJ, Ahn J, Hoe KL, Kim DU, Song KB Yoo HS (2007) Yeast-based screening to identify modulators of G-protein signaling using uncontrolled cell division cycle by overexpression of Stm1. J Biotechnol 129 : 547 554.
    • (2007) J Biotechnol , vol.129 , pp. 547-554
    • Chung, K.S.1    Won, M.2    Lee, J.J.3    Ahn, J.4    Hoe, K.L.5    Kim, D.U.6    Song, K.B.7    Yoo, H.S.8
  • 41
    • 0036616588 scopus 로고    scopus 로고
    • Molecular analysis of CPRalpha, a MATalpha-specific pheromone receptor gene of Cryptococcus neoformans
    • Chung S, Karos M, Chang YC, Lukszo J, Wickes BL Kwon-Chung KJ (2002) Molecular analysis of CPRalpha, a MATalpha-specific pheromone receptor gene of Cryptococcus neoformans. Eukaryot Cell 1 : 432 439.
    • (2002) Eukaryot Cell , vol.1 , pp. 432-439
    • Chung, S.1    Karos, M.2    Chang, Y.C.3    Lukszo, J.4    Wickes, B.L.5    Kwon-Chung, K.J.6
  • 42
    • 6344256284 scopus 로고    scopus 로고
    • Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae
    • Colombo S, Ronchetti D, Thevelein JM, Winderickx J Martegani E (2004) Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae. J Biol Chem 279 : 46715 46722.
    • (2004) J Biol Chem , vol.279 , pp. 46715-46722
    • Colombo, S.1    Ronchetti, D.2    Thevelein, J.M.3    Winderickx, J.4    Martegani, E.5
  • 43
    • 33751191884 scopus 로고    scopus 로고
    • Broad-spectrum l-amino acid sensing by class 3 G-protein-coupled receptors
    • Conigrave AD Hampson DR (2006) Broad-spectrum l-amino acid sensing by class 3 G-protein-coupled receptors. Trends Endocrinol Metab 17 : 398 407.
    • (2006) Trends Endocrinol Metab , vol.17 , pp. 398-407
    • Conigrave, A.D.1    Hampson, D.R.2
  • 44
    • 0037487244 scopus 로고    scopus 로고
    • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans
    • Davidson RC, Nichols CB, Cox GM, Perfect JR Heitman J (2003) A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. Mol Microbiol 49 : 469 485.
    • (2003) Mol Microbiol , vol.49 , pp. 469-485
    • Davidson, R.C.1    Nichols, C.B.2    Cox, G.M.3    Perfect, J.R.4    Heitman, J.5
  • 45
    • 0031912253 scopus 로고    scopus 로고
    • Afr1p regulates the Saccharomyces cerevisiae alpha-factor receptor by a mechanism that is distinct from receptor phosphorylation and endocytosis
    • Davis C, Dube P Konopka JB (1998) Afr1p regulates the Saccharomyces cerevisiae alpha-factor receptor by a mechanism that is distinct from receptor phosphorylation and endocytosis. Genetics 148 : 625 635.
    • (1998) Genetics , vol.148 , pp. 625-635
    • Davis, C.1    Dube, P.2    Konopka, J.B.3
  • 46
    • 30944435422 scopus 로고    scopus 로고
    • SST2, a regulator of G-protein signaling for the Candida albicans mating response pathway
    • Dignard D Whiteway M (2006) SST2, a regulator of G-protein signaling for the Candida albicans mating response pathway. Eukaryot Cell 5 : 192 202.
    • (2006) Eukaryot Cell , vol.5 , pp. 192-202
    • Dignard, D.1    Whiteway, M.2
  • 47
    • 41549156037 scopus 로고    scopus 로고
    • Signaling of human frizzled receptors to the mating pathway in yeast
    • Dirnberger D Seuwen K (2007) Signaling of human frizzled receptors to the mating pathway in yeast. PLoS One 2 : e954.
    • (2007) PLoS One , vol.2
    • Dirnberger, D.1    Seuwen, K.2
  • 48
    • 0034923514 scopus 로고    scopus 로고
    • Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
    • Dohlman HG Thorner JW (2001) Regulation of G protein-initiated signal transduction in yeast: paradigms and principles. Annu Rev Biochem 70 : 703 754.
    • (2001) Annu Rev Biochem , vol.70 , pp. 703-754
    • Dohlman, H.G.1    Thorner, J.W.2
  • 49
    • 33947601883 scopus 로고    scopus 로고
    • Pheromone signaling pathways in yeast
    • cm6.
    • Dohlman HG Slessareva JE (2006) Pheromone signaling pathways in yeast. Sci STKE 364 : cm6.
    • (2006) Sci STKE , vol.364
    • Dohlman, H.G.1    Slessareva, J.E.2
  • 50
    • 0029767982 scopus 로고    scopus 로고
    • Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: Expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit)
    • Dohlman HG, Song J, Ma D, Courchesne WE Thorner J (1996) Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol Cell Biol 16 : 5194 5209.
    • (1996) Mol Cell Biol , vol.16 , pp. 5194-5209
    • Dohlman, H.G.1    Song, J.2    Ma, D.3    Courchesne, W.E.4    Thorner, J.5
  • 51
    • 0031705403 scopus 로고    scopus 로고
    • Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments
    • Dosil M, Giot L, Davis C Konopka JB (1998) Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments. Mol Cell Biol 18 : 5981 5991.
    • (1998) Mol Cell Biol , vol.18 , pp. 5981-5991
    • Dosil, M.1    Giot, L.2    Davis, C.3    Konopka, J.B.4
  • 53
    • 0031915430 scopus 로고    scopus 로고
    • Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid
    • Erickson JR, Wu JJ, Goddard JG, Tigyi G, Kawanishi K, Tomei LD Kiefer MC (1998) Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid. J Biol Chem 273 : 1506 1510.
    • (1998) J Biol Chem , vol.273 , pp. 1506-1510
    • Erickson, J.R.1    Wu, J.J.2    Goddard, J.G.3    Tigyi, G.4    Kawanishi, K.5    Tomei, L.D.6    Kiefer, M.C.7
  • 54
    • 0034998457 scopus 로고    scopus 로고
    • Functional expression of M(1), M(3) and M(5) muscarinic acetylcholine receptors in yeast
    • Erlenbach I, Kostenis E, Schmidt C, Hamdan FF, Pausch MH Wess J (2001a) Functional expression of M(1), M(3) and M(5) muscarinic acetylcholine receptors in yeast. J Neurochem 77 : 1327 1337.
    • (2001) J Neurochem , vol.77 , pp. 1327-1337
    • Erlenbach, I.1    Kostenis, E.2    Schmidt, C.3    Hamdan, F.F.4    Pausch, M.H.5    Wess, J.6
  • 55
    • 0035800798 scopus 로고    scopus 로고
    • Single amino acid substitutions and deletions that alter the G protein coupling properties of the V2 vasopressin receptor identified in yeast by receptor random mutagenesis
    • Erlenbach I, Kostenis E, Schmidt C, Serradeil-Le Gal C, Raufaste D, Dumont ME, Pausch MH Wess J (2001b) Single amino acid substitutions and deletions that alter the G protein coupling properties of the V2 vasopressin receptor identified in yeast by receptor random mutagenesis. J Biol Chem 276 : 29382 29392.
    • (2001) J Biol Chem , vol.276 , pp. 29382-29392
    • Erlenbach, I.1    Kostenis, E.2    Schmidt, C.3    Serradeil-Le Gal, C.4    Raufaste, D.5    Dumont, M.E.6    Pausch, M.H.7    Wess, J.8
  • 56
    • 34547434085 scopus 로고    scopus 로고
    • Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit
    • Ernst OP, Gramse V, Kolbe M, Hofman KP Heck M (2007) Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit. Proc Natl Acad Sci USA 104 : 10859 10864.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 10859-10864
    • Ernst, O.P.1    Gramse, V.2    Kolbe, M.3    Hofman, K.P.4    Heck, M.5
  • 57
    • 34247219242 scopus 로고    scopus 로고
    • A regulator of a G protein signalling (RGS) gene, cag8, from the insect-pathogenic fungus Metarhizium anisopliae is involved in conidiation, virulence and hydrophobin synthesis
    • Fang W, Pei Y Bidochka MJ (2007) A regulator of a G protein signalling (RGS) gene, cag8, from the insect-pathogenic fungus Metarhizium anisopliae is involved in conidiation, virulence and hydrophobin synthesis. Microbiology 153 : 1017 1025.
    • (2007) Microbiology , vol.153 , pp. 1017-1025
    • Fang, W.1    Pei, Y.2    Bidochka, M.J.3
  • 58
    • 0041315583 scopus 로고    scopus 로고
    • C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast
    • Floyd DH, Geva A, Bruinsma SP, Overton MC, Blumer KJ Baranski TJ (2003) C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast. J Biol Chem 278 : 35354 35361.
    • (2003) J Biol Chem , vol.278 , pp. 35354-35361
    • Floyd, D.H.1    Geva, A.2    Bruinsma, S.P.3    Overton, M.C.4    Blumer, K.J.5    Baranski, T.J.6
  • 59
    • 0034528821 scopus 로고    scopus 로고
    • Scooter, a new active transposon in Schizophyllum commune, has disrupted two genes regulating signal transduction
    • Fowler TJ Mitton MF (2000) Scooter, a new active transposon in Schizophyllum commune, has disrupted two genes regulating signal transduction. Genetics 156 : 1585 1594.
    • (2000) Genetics , vol.156 , pp. 1585-1594
    • Fowler, T.J.1    Mitton, M.F.2
  • 60
    • 0032784390 scopus 로고    scopus 로고
    • Multiple sex pheromones and receptors of a mushroom-producing fungus elicit mating in yeast
    • Fowler TJ, DeSimone SM, Mitton MF, Kurjan J Raper CA (1999) Multiple sex pheromones and receptors of a mushroom-producing fungus elicit mating in yeast. Mol Biol Cell 10 : 2559 2572.
    • (1999) Mol Biol Cell , vol.10 , pp. 2559-2572
    • Fowler, T.J.1    Desimone, S.M.2    Mitton, M.F.3    Kurjan, J.4    Raper, C.A.5
  • 62
    • 40149100691 scopus 로고    scopus 로고
    • Evolution of the mating-type locus: The Basidiomycetes
    • Heitman, J., Kronstad, J.W., Taylor, J.W. Casselton, L.A., eds), pp. ASM Press, Washington, DC.
    • Fraser JA, Hsueh YP, Findley KM Heitman J (2007) Evolution of the mating-type locus: the Basidiomycetes. Sex in Fungi (Heitman J, Kronstad JW, Taylor JW Casselton LA, eds), pp. 19 34. ASM Press, Washington, DC.
    • (2007) Sex in Fungi , pp. 19-34
    • Fraser, J.A.1    Hsueh, Y.P.2    Findley, K.M.3    Heitman, J.4
  • 63
    • 33746339971 scopus 로고    scopus 로고
    • Oligomerization of the yeast alpha-factor receptor: Implications for dominant negative effects of mutant receptors
    • Gehret AU, Bajaj A, Naider F Dumont ME (2006) Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors. J Biol Chem 281 : 20698 20714.
    • (2006) J Biol Chem , vol.281 , pp. 20698-20714
    • Gehret, A.U.1    Bajaj, A.2    Naider, F.3    Dumont, M.E.4
  • 64
    • 0036780743 scopus 로고    scopus 로고
    • G-protein-coupled receptor oligomerization and its potential for drug discovery
    • George SR, O'Dowd BF Lee SP (2002) G-protein-coupled receptor oligomerization and its potential for drug discovery. Nat Rev Drug Discov 1 : 808 820.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 808-820
    • George, S.R.1    O'Dowd, B.F.2    Lee, S.P.3
  • 66
    • 0009447741 scopus 로고
    • Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: Gene sequence and implications for the structure of the presumed receptor
    • Hagen DC, McCaffrey G Sprague GF Jr. (1986) Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor. Proc Natl Acad Sci USA 83 : 1418 1422.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 1418-1422
    • Hagen, D.C.1    McCaffrey, G.2    Sprague Jr., G.F.3
  • 67
    • 1542407107 scopus 로고    scopus 로고
    • A putative G protein-coupled receptor negatively controls sexual development in Aspergillus nidulans
    • Han KH, Seo JA Yu JH (2004a) A putative G protein-coupled receptor negatively controls sexual development in Aspergillus nidulans. Mol Microbiol 51 : 1333 1345.
    • (2004) Mol Microbiol , vol.51 , pp. 1333-1345
    • Han, K.H.1    Seo, J.A.2    Yu, J.H.3
  • 68
    • 3242880573 scopus 로고    scopus 로고
    • Regulators of G-protein signalling in Aspergillus nidulans: RgsA downregulates stress response and stimulates asexual sporulation through attenuation of GanB (Galpha) signalling
    • Han KH, Seo JA Yu JH (2004b) Regulators of G-protein signalling in Aspergillus nidulans: RgsA downregulates stress response and stimulates asexual sporulation through attenuation of GanB (Galpha) signalling. Mol Microbiol 53 : 529 540.
    • (2004) Mol Microbiol , vol.53 , pp. 529-540
    • Han, K.H.1    Seo, J.A.2    Yu, J.H.3
  • 69
    • 41149090339 scopus 로고    scopus 로고
    • Regulation of GPCRs by endocytic membrane trafficking and its potential implications
    • Hanyaloglu AC von Zastrow M (2008) Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu Rev Pharmacol Toxicol 48 : 537 568.
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 537-568
    • Hanyaloglu, A.C.1    Von Zastrow, M.2
  • 70
    • 0035984604 scopus 로고    scopus 로고
    • The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits
    • Harashima T Heitman J (2002) The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. Mol Cell 10 : 163 173.
    • (2002) Mol Cell , vol.10 , pp. 163-173
    • Harashima, T.1    Heitman, J.2
  • 71
    • 26244457444 scopus 로고    scopus 로고
    • Galpha subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiae
    • Harashima T Heitman J (2005) Galpha subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiae. Mol Biol Cell 16 : 4557 4571.
    • (2005) Mol Biol Cell , vol.16 , pp. 4557-4571
    • Harashima, T.1    Heitman, J.2
  • 72
    • 33745199375 scopus 로고    scopus 로고
    • The kelch proteins Gpb1 and Gpb2 inhibit Ras activity via association with the yeast RasGAP neurofibromin homologs Ira1 and Ira2
    • Harashima T, Anderson S, Yates JR III. Heitman J (2006) The kelch proteins Gpb1 and Gpb2 inhibit Ras activity via association with the yeast RasGAP neurofibromin homologs Ira1 and Ira2. Mol Cell 22 : 819 830.
    • (2006) Mol Cell , vol.22 , pp. 819-830
    • Harashima, T.1    Anderson, S.2    Yates Iii., J.R.3    Heitman, J.4
  • 73
    • 0018928567 scopus 로고
    • Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone
    • Hartwell LH (1980) Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone. J Cell Biol 85 : 811 822.
    • (1980) J Cell Biol , vol.85 , pp. 811-822
    • Hartwell, L.H.1
  • 75
    • 0028985079 scopus 로고
    • MAP kinase pathways in yeast: For mating and more
    • Herskowitz I (1995) MAP kinase pathways in yeast: for mating and more. Cell 80 : 187 197.
    • (1995) Cell , vol.80 , pp. 187-197
    • Herskowitz, I.1
  • 76
    • 0030054178 scopus 로고    scopus 로고
    • Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis
    • Hicke L Riezman H (1996) Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84 : 277 287.
    • (1996) Cell , vol.84 , pp. 277-287
    • Hicke, L.1    Riezman, H.2
  • 77
    • 0032550179 scopus 로고    scopus 로고
    • Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization
    • Hicke L, Zanolari B Riezman H (1998) Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization. J Cell Biol 141 : 349 358.
    • (1998) J Cell Biol , vol.141 , pp. 349-358
    • Hicke, L.1    Zanolari, B.2    Riezman, H.3
  • 78
    • 0030839254 scopus 로고    scopus 로고
    • Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway
    • Hicks JK, Yu JH, Keller NP Adams TH (1997) Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway. EMBO J 16 : 4916 4923.
    • (1997) EMBO J , vol.16 , pp. 4916-4923
    • Hicks, J.K.1    Yu, J.H.2    Keller, N.P.3    Adams, T.H.4
  • 79
    • 40949097281 scopus 로고    scopus 로고
    • Eighty years after its discovery, Fleming's Penicillium strain discloses the secret of its sex
    • Hoff B, Poggeler S Kuck U (2008) Eighty years after its discovery, Fleming's Penicillium strain discloses the secret of its sex. Eukaryot Cell 7 : 465 470.
    • (2008) Eukaryot Cell , vol.7 , pp. 465-470
    • Hoff, B.1    Poggeler, S.2    Kuck, U.3
  • 80
    • 14644435106 scopus 로고    scopus 로고
    • Glucose sensing via the protein kinase a pathway in Schizosaccharomyces pombe
    • Hoffman CS (2005) Glucose sensing via the protein kinase A pathway in Schizosaccharomyces pombe. Biochem Soc Trans 33 : 257 260.
    • (2005) Biochem Soc Trans , vol.33 , pp. 257-260
    • Hoffman, C.S.1
  • 81
    • 34548478560 scopus 로고    scopus 로고
    • G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans
    • Hsueh YP, Xue C Heitman J (2007) G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans. Mol Biol Cell 18 : 3237 3249.
    • (2007) Mol Biol Cell , vol.18 , pp. 3237-3249
    • Hsueh, Y.P.1    Xue, C.2    Heitman, J.3
  • 82
    • 0036948447 scopus 로고    scopus 로고
    • Genetics of Cryptococcus neoformans
    • Hull CM Heitman J (2002) Genetics of Cryptococcus neoformans. Annu Rev Genet 36 : 557 615.
    • (2002) Annu Rev Genet , vol.36 , pp. 557-615
    • Hull, C.M.1    Heitman, J.2
  • 83
    • 17844395528 scopus 로고    scopus 로고
    • Light controls growth and development via a conserved pathway in the fungal kingdom
    • Idnurm A Heitman J (2005) Light controls growth and development via a conserved pathway in the fungal kingdom. PLoS Biol 3 : e95.
    • (2005) PLoS Biol , vol.3
    • Idnurm, A.1    Heitman, J.2
  • 84
    • 0035058358 scopus 로고    scopus 로고
    • Characterization of an opsin gene from the ascomycete Leptosphaeria maculans
    • Idnurm A Howlett BJ (2001) Characterization of an opsin gene from the ascomycete Leptosphaeria maculans. Genome 44 : 167 171.
    • (2001) Genome , vol.44 , pp. 167-171
    • Idnurm, A.1    Howlett, B.J.2
  • 85
    • 0037434991 scopus 로고    scopus 로고
    • Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40
    • Itoh Y, Kawamata Y, Harada M et al 2003) Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 422 : 173 176.
    • (2003) Nature , vol.422 , pp. 173-176
    • Itoh, Y.1    Kawamata, Y.2    Harada, M.3    Al, E.4
  • 86
    • 33645217329 scopus 로고    scopus 로고
    • Evolution of the bipolar mating system of the mushroom Coprinellus disseminatus from its tetrapolar ancestors involves loss of mating-type-specific pheromone receptor function
    • James TY, Srivilai P, Kues U Vilgalys R (2006) Evolution of the bipolar mating system of the mushroom Coprinellus disseminatus from its tetrapolar ancestors involves loss of mating-type-specific pheromone receptor function. Genetics 172 : 1877 1891.
    • (2006) Genetics , vol.172 , pp. 1877-1891
    • James, T.Y.1    Srivilai, P.2    Kues, U.3    Vilgalys, R.4
  • 87
    • 33748508863 scopus 로고    scopus 로고
    • Regulatory mechanisms involved in modulating RGS function
    • Jean-Baptiste G, Yang Z Greenwood MT (2006) Regulatory mechanisms involved in modulating RGS function. Cell Mol Life Sci 63 : 1969 1985.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 1969-1985
    • Jean-Baptiste, G.1    Yang, Z.2    Greenwood, M.T.3
  • 88
    • 53749090478 scopus 로고    scopus 로고
    • Mating in the smut fungi: From a to b to the downstream cascades
    • Heitman, J., Kronstad, J.W., Taylor, J.W. Casselton, L.A., eds), pp. ASM Press, Washington, DC.
    • Kahmann R Schirrawski J (2007) Mating in the smut fungi: from a to b to the downstream cascades. Sex in Fungi (Heitman J, Kronstad JW, Taylor JW Casselton LA, eds), pp. 377 387. ASM Press, Washington, DC.
    • (2007) Sex in Fungi , pp. 377-387
    • Kahmann, R.1    Schirrawski, J.2
  • 89
    • 0031036423 scopus 로고    scopus 로고
    • Investigation of growth hormone releasing hormone receptor structure and activity using yeast expression technologies
    • Kajkowski EM, Price LA, Pausch MH, Young KH Ozenberger BA (1997) Investigation of growth hormone releasing hormone receptor structure and activity using yeast expression technologies. J Recept Signal Transduct Res 17 : 293 303.
    • (1997) J Recept Signal Transduct Res , vol.17 , pp. 293-303
    • Kajkowski, E.M.1    Price, L.A.2    Pausch, M.H.3    Young, K.H.4    Ozenberger, B.A.5
  • 90
    • 36949092394 scopus 로고
    • Pheromones: A new term for a class of biologically active substances
    • Karlson P Luscher M (1959) Pheromones: a new term for a class of biologically active substances. Nature 183 : 55 56.
    • (1959) Nature , vol.183 , pp. 55-56
    • Karlson, P.1    Luscher, M.2
  • 91
    • 18744394931 scopus 로고    scopus 로고
    • New eyes to see texture in ligand efficacy
    • Kenakin TP (2005) New eyes to see texture in ligand efficacy. Nat Methods 2 : 163 164.
    • (2005) Nat Methods , vol.2 , pp. 163-164
    • Kenakin, T.P.1
  • 92
    • 3042590310 scopus 로고    scopus 로고
    • A pheromone receptor gene, pre-1, is essential for mating type-specific directional growth and fusion of trichogynes and female fertility in Neurospora crassa
    • Kim H Borkovich KA (2004) A pheromone receptor gene, pre-1, is essential for mating type-specific directional growth and fusion of trichogynes and female fertility in Neurospora crassa. Mol Microbiol 52 : 1781 1798.
    • (2004) Mol Microbiol , vol.52 , pp. 1781-1798
    • Kim, H.1    Borkovich, K.A.2
  • 93
    • 33645056427 scopus 로고    scopus 로고
    • Pheromones are essential for male fertility and sufficient to direct chemotropic polarized growth of trichogynes during mating in Neurospora crassa
    • Kim H Borkovich KA (2006) Pheromones are essential for male fertility and sufficient to direct chemotropic polarized growth of trichogynes during mating in Neurospora crassa. Eukaryot Cell 5 : 544 554.
    • (2006) Eukaryot Cell , vol.5 , pp. 544-554
    • Kim, H.1    Borkovich, K.A.2
  • 94
    • 0025153120 scopus 로고
    • Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit
    • King K, Dohlman HG, Thorner J, Caron MG Lefkowitz RJ (1990) Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. Science 250 : 121 123.
    • (1990) Science , vol.250 , pp. 121-123
    • King, K.1    Dohlman, H.G.2    Thorner, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 95
    • 0025943077 scopus 로고
    • The Schizosaccharomyces pombe mam2 gene encodes a putative pheromone receptor which has a significant homology with the Saccharomyces cerevisiae Ste2 protein
    • Kitamura K Shimoda C (1991) The Schizosaccharomyces pombe mam2 gene encodes a putative pheromone receptor which has a significant homology with the Saccharomyces cerevisiae Ste2 protein. EMBO J 10 : 3743 3751.
    • (1991) EMBO J , vol.10 , pp. 3743-3751
    • Kitamura, K.1    Shimoda, C.2
  • 97
    • 33745685058 scopus 로고    scopus 로고
    • Heterotrimeric G protein signaling: Getting inside the cell
    • Koelle MR (2006) Heterotrimeric G protein signaling: getting inside the cell. Cell 126 : 25 27.
    • (2006) Cell , vol.126 , pp. 25-27
    • Koelle, M.R.1
  • 98
    • 0032547154 scopus 로고    scopus 로고
    • Mutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor function
    • Kokkola T, Watson MA, White J, Dowell S, Foord SM Laitinen JT (1998) Mutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor function. Biochem Biophys Res Commun 249 : 531 536.
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 531-536
    • Kokkola, T.1    Watson, M.A.2    White, J.3    Dowell, S.4    Foord, S.M.5    Laitinen, J.T.6
  • 99
    • 0028338534 scopus 로고
    • GCRDb: A G-protein-coupled receptor database
    • Kolakowski LF Jr. (1994) GCRDb: a G-protein-coupled receptor database. Receptors Channels 2 : 1 7.
    • (1994) Receptors Channels , vol.2 , pp. 1-7
    • Kolakowski Jr., L.F.1
  • 100
    • 0030990397 scopus 로고    scopus 로고
    • A novel system that reports the G-proteins linked to a given receptor: A study of type 3 somatostatin receptor
    • Komatsuzaki K, Murayama Y, Giambarella U, Ogata E, Seino S Nishimoto I (1997) A novel system that reports the G-proteins linked to a given receptor: a study of type 3 somatostatin receptor. FEBS Lett 406 : 165 170.
    • (1997) FEBS Lett , vol.406 , pp. 165-170
    • Komatsuzaki, K.1    Murayama, Y.2    Giambarella, U.3    Ogata, E.4    Seino, S.5    Nishimoto, I.6
  • 101
    • 0027494567 scopus 로고
    • AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation
    • Konopka JB (1993) AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation. Mol Cell Biol 13 : 6876 6888.
    • (1993) Mol Cell Biol , vol.13 , pp. 6876-6888
    • Konopka, J.B.1
  • 102
    • 0029900790 scopus 로고    scopus 로고
    • Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor
    • Konopka JB, Margarit SM Dube P (1996) Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor. Proc Natl Acad Sci USA 93 : 6764 6769.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6764-6769
    • Konopka, J.B.1    Margarit, S.M.2    Dube, P.3
  • 103
    • 0020353195 scopus 로고
    • Modulation of sodium-sensitive GTPase by partial opiate agonists. An explanation for the dual requirement for Na+and GTP in inhibitory regulation of adenylate cyclase
    • Koski G, Streaty RA Klee WA (1982) Modulation of sodium-sensitive GTPase by partial opiate agonists. An explanation for the dual requirement for Na+and GTP in inhibitory regulation of adenylate cyclase. J Biol Chem 257 : 14035 14040.
    • (1982) J Biol Chem , vol.257 , pp. 14035-14040
    • Koski, G.1    Streaty, R.A.2    Klee, W.A.3
  • 104
    • 3042856569 scopus 로고    scopus 로고
    • A glance at G-protein-coupled receptors for lipid mediators: A growing receptor family with remarkably diverse ligands
    • Kostenis E (2004) A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands. Pharmacol Ther 102 : 243 257.
    • (2004) Pharmacol Ther , vol.102 , pp. 243-257
    • Kostenis, E.1
  • 105
    • 0030879688 scopus 로고    scopus 로고
    • Genetic analysis of receptor-Galphaq coupling selectivity
    • Kostenis E, Gomeza J, Lerche C Wess J (1997) Genetic analysis of receptor-Galphaq coupling selectivity. J Biol Chem 272 : 23675 23681.
    • (1997) J Biol Chem , vol.272 , pp. 23675-23681
    • Kostenis, E.1    Gomeza, J.2    Lerche, C.3    Wess, J.4
  • 106
    • 0032986914 scopus 로고    scopus 로고
    • A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose
    • Kraakman L, Lemaire K, Ma P, Teunissen AW, Donaton MC, Van Dijck P, Winderickx J, de Winde JH Thevelein JM (1999) A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose. Mol Microbiol 32 : 1002 1012.
    • (1999) Mol Microbiol , vol.32 , pp. 1002-1012
    • Kraakman, L.1    Lemaire, K.2    Ma, P.3    Teunissen, A.W.4    Donaton, M.C.5    Van Dijck, P.6    Winderickx, J.7    De Winde, J.H.8    Thevelein, J.M.9
  • 107
    • 0031453252 scopus 로고    scopus 로고
    • Mating type in filamentous fungi
    • Kronstad JW Staben C (1997) Mating type in filamentous fungi. Annu Rev Genet 31 : 245 276.
    • (1997) Annu Rev Genet , vol.31 , pp. 245-276
    • Kronstad, J.W.1    Staben, C.2
  • 108
    • 0024833061 scopus 로고
    • Saccharomyces cerevisiae STE6 gene product: A novel pathway for protein export in eukaryotic cells
    • Kuchler K, Sterne RE Thorner J (1989) Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J 8 : 3973 3984.
    • (1989) EMBO J , vol.8 , pp. 3973-3984
    • Kuchler, K.1    Sterne, R.E.2    Thorner, J.3
  • 109
    • 27944509040 scopus 로고    scopus 로고
    • Novel G-protein-coupled receptor-like proteins in the plant pathogenic fungus Magnaporthe grisea
    • Kulkarni RD, Thon MR, Pan H Dean RA (2005) Novel G-protein-coupled receptor-like proteins in the plant pathogenic fungus Magnaporthe grisea. Genome Biol 6 : R24.
    • (2005) Genome Biol , vol.6
    • Kulkarni, R.D.1    Thon, M.R.2    Pan, H.3    Dean, R.A.4
  • 110
    • 13144265744 scopus 로고    scopus 로고
    • A constitutively active GPCR retains its G protein specificity and the ability to form dimers
    • Ladds G, Davis K, Das A Davey J (2005) A constitutively active GPCR retains its G protein specificity and the ability to form dimers. Mol Microbiol 55 : 482 497.
    • (2005) Mol Microbiol , vol.55 , pp. 482-497
    • Ladds, G.1    Davis, K.2    Das, A.3    Davey, J.4
  • 111
    • 26444568777 scopus 로고    scopus 로고
    • The heterotrimeric G-protein GanB(alpha)-SfaD(beta)-GpgA(gamma) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans
    • Lafon A, Seo JA, Han KH, Yu JH d'Enfert C (2005) The heterotrimeric G-protein GanB(alpha)-SfaD(beta)-GpgA(gamma) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans. Genetics 171 : 71 80.
    • (2005) Genetics , vol.171 , pp. 71-80
    • Lafon, A.1    Seo, J.A.2    Han, K.H.3    Yu, J.H.4    D'Enfert, C.5
  • 112
    • 33646730081 scopus 로고    scopus 로고
    • G-protein and cAMP-mediated signaling in aspergilli: A genomic perspective
    • Lafon A, Han KH, Seo JA, Yu JH d'Enfert C (2006) G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective. Fungal Genet Biol 43 : 490 502.
    • (2006) Fungal Genet Biol , vol.43 , pp. 490-502
    • Lafon, A.1    Han, K.H.2    Seo, J.A.3    Yu, J.H.4    D'Enfert, C.5
  • 113
    • 0032788711 scopus 로고    scopus 로고
    • Dominant negative mutations in the alpha-factor receptor, a G protein-coupled receptor encoded by the STE2 gene of the yeast Saccharomyces cerevisiae
    • Leavitt LM, Macaluso CR, Kim KS, Martin NP Dumont ME (1999) Dominant negative mutations in the alpha-factor receptor, a G protein-coupled receptor encoded by the STE2 gene of the yeast Saccharomyces cerevisiae. Mol Gen Genet 261 : 917 932.
    • (1999) Mol Gen Genet , vol.261 , pp. 917-932
    • Leavitt, L.M.1    MacAluso, C.R.2    Kim, K.S.3    Martin, N.P.4    Dumont, M.E.5
  • 114
    • 38849206178 scopus 로고    scopus 로고
    • Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor
    • Lee MJ Dohlman HG (2008) Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor. Curr Biol 18 : 211 215.
    • (2008) Curr Biol , vol.18 , pp. 211-215
    • Lee, M.J.1    Dohlman, H.G.2
  • 115
    • 0032495478 scopus 로고    scopus 로고
    • Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases
    • Leeuw T, Wu C, Schrag JD, Whiteway M, Thomas DY Leberer E (1998) Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases. Nature 391 : 191 195.
    • (1998) Nature , vol.391 , pp. 191-195
    • Leeuw, T.1    Wu, C.2    Schrag, J.D.3    Whiteway, M.4    Thomas, D.Y.5    Leberer, E.6
  • 116
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz RJ Shenoy SK (2005) Transduction of receptor signals by beta-arrestins. Science 308 : 512 517.
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 117
    • 6344280942 scopus 로고    scopus 로고
    • Glucose and sucrose act as agonist and mannose as antagonist ligands of the G protein-coupled receptor Gpr1 in the yeast Saccharomyces cerevisiae
    • Lemaire K, Van de Velde S, Van Dijck P Thevelein JM (2004) Glucose and sucrose act as agonist and mannose as antagonist ligands of the G protein-coupled receptor Gpr1 in the yeast Saccharomyces cerevisiae. Mol Cell 16 : 293 299.
    • (2004) Mol Cell , vol.16 , pp. 293-299
    • Lemaire, K.1    Van De Velde, S.2    Van Dijck, P.3    Thevelein, J.M.4
  • 120
    • 0034796384 scopus 로고    scopus 로고
    • Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor
    • Leplatois P, Josse A, Guillemot M, Febvre M, Vita N, Ferrara P Loison G (2001) Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor. Eur J Biochem 268 : 4860 4867.
    • (2001) Eur J Biochem , vol.268 , pp. 4860-4867
    • Leplatois, P.1    Josse, A.2    Guillemot, M.3    Febvre, M.4    Vita, N.5    Ferrara, P.6    Loison, G.7
  • 121
    • 33747346748 scopus 로고    scopus 로고
    • GPR-4 is a predicted G-protein-coupled receptor required for carbon source-dependent asexual growth and development in Neurospora crassa
    • Li L Borkovich KA (2006) GPR-4 is a predicted G-protein-coupled receptor required for carbon source-dependent asexual growth and development in Neurospora crassa. Eukaryot Cell 5 : 1287 1300.
    • (2006) Eukaryot Cell , vol.5 , pp. 1287-1300
    • Li, L.1    Borkovich, K.A.2
  • 122
    • 35948947869 scopus 로고    scopus 로고
    • Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans
    • Li L, Shen G, Zhang ZG, Wang YL, Thompson JK Wang P (2007a) Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans. Mol Biol Cell 18 : 4201 4209.
    • (2007) Mol Biol Cell , vol.18 , pp. 4201-4209
    • Li, L.1    Shen, G.2    Zhang, Z.G.3    Wang, Y.L.4    Thompson, J.K.5    Wang, P.6
  • 124
    • 33846943303 scopus 로고    scopus 로고
    • Rgs1 regulates multiple Galpha subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism
    • Liu H, Suresh A, Willard FS, Siderovski DP, Lu S Naqvi NI (2007) Rgs1 regulates multiple Galpha subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism. EMBO J 26 : 690 700.
    • (2007) EMBO J , vol.26 , pp. 690-700
    • Liu, H.1    Suresh, A.2    Willard, F.S.3    Siderovski, D.P.4    Lu, S.5    Naqvi, N.I.6
  • 126
    • 0033967762 scopus 로고    scopus 로고
    • The G protein-coupled receptor Gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae
    • Lorenz MC, Pan X, Harashima T, Cardenas ME, Xue Y, Hirsch JP Heitman J (2000) The G protein-coupled receptor Gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Genetics 154 : 609 622.
    • (2000) Genetics , vol.154 , pp. 609-622
    • Lorenz, M.C.1    Pan, X.2    Harashima, T.3    Cardenas, M.E.4    Xue, Y.5    Hirsch, J.P.6    Heitman, J.7
  • 127
    • 0015959499 scopus 로고
    • Mutations affecting sexual conjugation and related processes in Saccharomyces cerevisiae. I. Isolation and phenotypic characterization of nonmating mutants
    • Mackay V Manney TR (1974) Mutations affecting sexual conjugation and related processes in Saccharomyces cerevisiae. I. Isolation and phenotypic characterization of nonmating mutants. Genetics 76 : 255 271.
    • (1974) Genetics , vol.76 , pp. 255-271
    • MacKay, V.1    Manney, T.R.2
  • 128
    • 16344394213 scopus 로고    scopus 로고
    • The G protein-coupled receptor Gpr1 and the G{alpha} protein Gpa2 act through the cAMP-protein kinase a pathway to induce morphogenesis in Candida albicans
    • Maidan MM, De Rop L, Serneels J, Exler S, Rupp S, Tournu H, Thevelein JM Van Dijck P (2005a) The G protein-coupled receptor Gpr1 and the G{alpha} protein Gpa2 act through the cAMP-protein kinase A pathway to induce morphogenesis in Candida albicans. Mol Biol Cell 16 : 1971 1986.
    • (2005) Mol Biol Cell , vol.16 , pp. 1971-1986
    • Maidan, M.M.1    De Rop, L.2    Serneels, J.3    Exler, S.4    Rupp, S.5    Tournu, H.6    Thevelein, J.M.7    Van Dijck, P.8
  • 129
    • 14644415945 scopus 로고    scopus 로고
    • Carbon source induced yeast-to-hypha transition in Candida albicans is dependent on the presence of amino acids and on the G-protein-coupled receptor Gpr1
    • Maidan MM, Thevelein JM Van Dijck P (2005b) Carbon source induced yeast-to-hypha transition in Candida albicans is dependent on the presence of amino acids and on the G-protein-coupled receptor Gpr1. Biochem Soc Trans 33 : 291 293.
    • (2005) Biochem Soc Trans , vol.33 , pp. 291-293
    • Maidan, M.M.1    Thevelein, J.M.2    Van Dijck, P.3
  • 130
    • 42149193288 scopus 로고    scopus 로고
    • Combined inactivation of the Candida albicans GPR1 and TPS2 genes results in avirulence in a mouse model for systemic infection
    • Maidan MM, De Rop L, Relloso M, Diez-Orejas R, Thevelein JM Van Dijck P (2008) Combined inactivation of the Candida albicans GPR1 and TPS2 genes results in avirulence in a mouse model for systemic infection. Infect Immun 76 : 1686 1694.
    • (2008) Infect Immun , vol.76 , pp. 1686-1694
    • Maidan, M.M.1    De Rop, L.2    Relloso, M.3    Diez-Orejas, R.4    Thevelein, J.M.5    Van Dijck, P.6
  • 131
    • 0037980255 scopus 로고    scopus 로고
    • Signal transduction. Fishing at the cell surface
    • Maller JL (2003) Signal transduction. Fishing at the cell surface. Science 300 : 594 595.
    • (2003) Science , vol.300 , pp. 594-595
    • Maller, J.L.1
  • 132
    • 33645221485 scopus 로고    scopus 로고
    • Pheromones and pheromone receptors are required for proper sexual development in the homothallic ascomycete Sordaria macrospora
    • Mayrhofer S, Weber JM Poggeler S (2006) Pheromones and pheromone receptors are required for proper sexual development in the homothallic ascomycete Sordaria macrospora. Genetics 172 : 1521 1533.
    • (2006) Genetics , vol.172 , pp. 1521-1533
    • Mayrhofer, S.1    Weber, J.M.2    Poggeler, S.3
  • 133
    • 0035719181 scopus 로고    scopus 로고
    • Functional assays for mammalian G-protein-coupled receptors in yeast
    • Mentesana PE, Dosil M Konopka JB (2002) Functional assays for mammalian G-protein-coupled receptors in yeast. Methods Enzymol 344 : 92 111.
    • (2002) Methods Enzymol , vol.344 , pp. 92-111
    • Mentesana, P.E.1    Dosil, M.2    Konopka, J.B.3
  • 134
    • 33144473025 scopus 로고    scopus 로고
    • FRET imaging reveals that functional neurokinin-1 receptors are monomeric and reside in membrane microdomains of live cells
    • Meyer BH, Segura JM, Martinez KL, Hovius R, George N, Johnsson K Vogel H (2006) FRET imaging reveals that functional neurokinin-1 receptors are monomeric and reside in membrane microdomains of live cells. Proc Natl Acad Sci USA 103 : 2138 2143.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2138-2143
    • Meyer, B.H.1    Segura, J.M.2    Martinez, K.L.3    Hovius, R.4    George, N.5    Johnsson, K.6    Vogel, H.7
  • 135
    • 3042663287 scopus 로고    scopus 로고
    • G protein-coupled receptor dimerization: Function and ligand pharmacology
    • Milligan G (2004) G protein-coupled receptor dimerization: function and ligand pharmacology. Mol Pharmacol 66 : 1 7.
    • (2004) Mol Pharmacol , vol.66 , pp. 1-7
    • Milligan, G.1
  • 136
    • 33646526069 scopus 로고    scopus 로고
    • G-protein-coupled receptor heterodimers: Pharmacology, function and relevance to drug discovery
    • Milligan G (2006) G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery. Drug Discov Today 11 : 541 549.
    • (2006) Drug Discov Today , vol.11 , pp. 541-549
    • Milligan, G.1
  • 137
    • 12544250956 scopus 로고    scopus 로고
    • Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening
    • Minic J, Persuy MA, Godel E, Aioun J, Connerton I, Salesse R Pajot-Augy E (2005a) Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening. FEBS J 272 : 524 537.
    • (2005) FEBS J , vol.272 , pp. 524-537
    • Minic, J.1    Persuy, M.A.2    Godel, E.3    Aioun, J.4    Connerton, I.5    Salesse, R.6    Pajot-Augy, E.7
  • 138
    • 15944366921 scopus 로고    scopus 로고
    • Yeast system as a screening tool for pharmacological assessment of G protein coupled receptors
    • Minic J, Sautel M, Salesse R Pajot-Augy E (2005b) Yeast system as a screening tool for pharmacological assessment of G protein coupled receptors. Curr Med Chem 12 : 961 969.
    • (2005) Curr Med Chem , vol.12 , pp. 961-969
    • Minic, J.1    Sautel, M.2    Salesse, R.3    Pajot-Augy, E.4
  • 139
    • 0036510377 scopus 로고    scopus 로고
    • Functional expression of heteromeric calcitonin gene-related peptide and adrenomedullin receptors in yeast
    • Miret JJ, Rakhilina L, Silverman L Oehlen B (2002) Functional expression of heteromeric calcitonin gene-related peptide and adrenomedullin receptors in yeast. J Biol Chem 277 : 6881 6887.
    • (2002) J Biol Chem , vol.277 , pp. 6881-6887
    • Miret, J.J.1    Rakhilina, L.2    Silverman, L.3    Oehlen, B.4
  • 140
    • 4143137516 scopus 로고    scopus 로고
    • Gpr1, a putative G-protein-coupled receptor, regulates morphogenesis and hypha formation in the pathogenic fungus Candida albicans
    • Miwa T, Takagi Y, Shinozaki M, Yun CW, Schell WA, Perfect JR, Kumagai H Tamaki H (2004) Gpr1, a putative G-protein-coupled receptor, regulates morphogenesis and hypha formation in the pathogenic fungus Candida albicans. Eukaryot Cell 3 : 919 931.
    • (2004) Eukaryot Cell , vol.3 , pp. 919-931
    • Miwa, T.1    Takagi, Y.2    Shinozaki, M.3    Yun, C.W.4    Schell, W.A.5    Perfect, J.R.6    Kumagai, H.7    Tamaki, H.8
  • 141
    • 47049120414 scopus 로고    scopus 로고
    • The asexual yeast Candida glabrata maintains distinct a and alpha haploid mating types
    • Muller H, Hennequin C, Gallaud J, Dujon B Fairhead C (2008) The asexual yeast Candida glabrata maintains distinct a and alpha haploid mating types. Eukaryot Cell 7 : 848 858.
    • (2008) Eukaryot Cell , vol.7 , pp. 848-858
    • Muller, H.1    Hennequin, C.2    Gallaud, J.3    Dujon, B.4    Fairhead, C.5
  • 145
    • 0041971075 scopus 로고    scopus 로고
    • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates
    • Nielsen K, Cox GM, Wang P, Toffaletti DL, Perfect JR Heitman J (2003) Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. Infect Immun 71 : 4831 4841.
    • (2003) Infect Immun , vol.71 , pp. 4831-4841
    • Nielsen, K.1    Cox, G.M.2    Wang, P.3    Toffaletti, D.L.4    Perfect, J.R.5    Heitman, J.6
  • 146
    • 0029283796 scopus 로고
    • Pheromone communication in the fission yeast Schizosaccharomyces pombe
    • Nielsen O Davey J (1995) Pheromone communication in the fission yeast Schizosaccharomyces pombe. Semin Cell Biol 6 : 95 104.
    • (1995) Semin Cell Biol , vol.6 , pp. 95-104
    • Nielsen, O.1    Davey, J.2
  • 147
    • 0035055325 scopus 로고    scopus 로고
    • Pathogenic yeasts Cryptococcus neoformans and Candida albicans produce immunomodulatory prostaglandins
    • Noverr MC, Phare SM, Toews GB, Coffey MJ Huffnagle GB (2001) Pathogenic yeasts Cryptococcus neoformans and Candida albicans produce immunomodulatory prostaglandins. Infect Immun 69 : 2957 2963.
    • (2001) Infect Immun , vol.69 , pp. 2957-2963
    • Noverr, M.C.1    Phare, S.M.2    Toews, G.B.3    Coffey, M.J.4    Huffnagle, G.B.5
  • 149
    • 0034704906 scopus 로고    scopus 로고
    • G-protein-coupled receptors function as oligomers in vivo
    • Overton MC Blumer KJ (2000) G-protein-coupled receptors function as oligomers in vivo. Curr Biol 10 : 341 344.
    • (2000) Curr Biol , vol.10 , pp. 341-344
    • Overton, M.C.1    Blumer, K.J.2
  • 150
    • 1542467519 scopus 로고    scopus 로고
    • Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor
    • Overton MC, Chinault SL Blumer KJ (2003) Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor. J Biol Chem 278 : 49369 49377.
    • (2003) J Biol Chem , vol.278 , pp. 49369-49377
    • Overton, M.C.1    Chinault, S.L.2    Blumer, K.J.3
  • 151
    • 29144466481 scopus 로고    scopus 로고
    • Oligomerization of G-protein-coupled receptors: Lessons from the yeast Saccharomyces cerevisiae
    • Overton MC, Chinault SL Blumer KJ (2005) Oligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae. Eukaryot Cell 4 : 1963 1970.
    • (2005) Eukaryot Cell , vol.4 , pp. 1963-1970
    • Overton, M.C.1    Chinault, S.L.2    Blumer, K.J.3
  • 153
    • 0034604451 scopus 로고    scopus 로고
    • Crystal structure of rhodopsin: A G protein-coupled receptor
    • Palczewski K, Kumasaka T, Hori T et al 2000) Crystal structure of rhodopsin: a G protein-coupled receptor. Science 289 : 739 745.
    • (2000) Science , vol.289 , pp. 739-745
    • Palczewski, K.1    Kumasaka, T.2    Hori, T.3    Al, E.4
  • 154
    • 33845936006 scopus 로고    scopus 로고
    • Gib2, a novel Gbeta-like/RACK1 homolog, functions as a Gbeta subunit in cAMP signaling and is essential in Cryptococcus neoformans
    • Palmer DA, Thompson JK, Li L, Prat A Wang P (2006) Gib2, a novel Gbeta-like/RACK1 homolog, functions as a Gbeta subunit in cAMP signaling and is essential in Cryptococcus neoformans. J Biol Chem 281 : 32596 32605.
    • (2006) J Biol Chem , vol.281 , pp. 32596-32605
    • Palmer, D.A.1    Thompson, J.K.2    Li, L.3    Prat, A.4    Wang, P.5
  • 157
    • 10844255797 scopus 로고    scopus 로고
    • Oligomerization of G protein-coupled receptors: Past, present, and future
    • Park PS, Filipek S, Wells JW Palczewski K (2004) Oligomerization of G protein-coupled receptors: past, present, and future. Biochemistry 43 : 15643 15656.
    • (2004) Biochemistry , vol.43 , pp. 15643-15656
    • Park, P.S.1    Filipek, S.2    Wells, J.W.3    Palczewski, K.4
  • 158
    • 33748368267 scopus 로고    scopus 로고
    • Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase a in yeast
    • Peeters T, Louwet W, Gelade R, Nauwelaers D, Thevelein JM Versele M (2006) Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast. Proc Natl Acad Sci USA 103 : 13034 13039.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13034-13039
    • Peeters, T.1    Louwet, W.2    Gelade, R.3    Nauwelaers, D.4    Thevelein, J.M.5    Versele, M.6
  • 159
    • 34447105864 scopus 로고    scopus 로고
    • Resistance to echinocandin-class antifungal drugs
    • Perlin DS (2007) Resistance to echinocandin-class antifungal drugs. Drug Resist Updat 10 : 121 130.
    • (2007) Drug Resist Updat , vol.10 , pp. 121-130
    • Perlin, D.S.1
  • 160
    • 0035660374 scopus 로고    scopus 로고
    • Identification of transcriptionally expressed pheromone receptor genes in filamentous ascomycetes
    • Poggeler S Kuck U (2001) Identification of transcriptionally expressed pheromone receptor genes in filamentous ascomycetes. Gene 280 : 9 17.
    • (2001) Gene , vol.280 , pp. 9-17
    • Poggeler, S.1    Kuck, U.2
  • 161
    • 0028840683 scopus 로고
    • Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway
    • Price LA, Kajkowski EM, Hadcock JR, Ozenberger BA Pausch MH (1995) Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. Mol Cell Biol 15 : 6188 6195.
    • (1995) Mol Cell Biol , vol.15 , pp. 6188-6195
    • Price, L.A.1    Kajkowski, E.M.2    Hadcock, J.R.3    Ozenberger, B.A.4    Pausch, M.H.5
  • 162
    • 0029862555 scopus 로고    scopus 로고
    • Pharmacological characterization of the rat A2a adenosine receptor functionally coupled to the yeast pheromone response pathway
    • Price LA, Strnad J, Pausch MH Hadcock JR (1996) Pharmacological characterization of the rat A2a adenosine receptor functionally coupled to the yeast pheromone response pathway. Mol Pharmacol 50 : 829 837.
    • (1996) Mol Pharmacol , vol.50 , pp. 829-837
    • Price, L.A.1    Strnad, J.2    Pausch, M.H.3    Hadcock, J.R.4
  • 163
    • 0032168881 scopus 로고    scopus 로고
    • Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway
    • Pryciak PM Huntress FA (1998) Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway. Genes Dev 12 : 2684 2697.
    • (1998) Genes Dev , vol.12 , pp. 2684-2697
    • Pryciak, P.M.1    Huntress, F.A.2
  • 164
    • 0742269682 scopus 로고    scopus 로고
    • Cyclic AMP signaling in Cryptococcus neoformans
    • Pukkila-Worley R Alspaugh JA (2004) Cyclic AMP signaling in Cryptococcus neoformans. FEMS Yeast Res 4 : 361 367.
    • (2004) FEMS Yeast Res , vol.4 , pp. 361-367
    • Pukkila-Worley, R.1    Alspaugh, J.A.2
  • 166
    • 36248970132 scopus 로고    scopus 로고
    • Crystal structure of the human beta2 adrenergic G-protein-coupled receptor
    • Rasmussen SG, Choi HJ, Rosenbaum DM et al 2007) Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature 450 : 383 387.
    • (2007) Nature , vol.450 , pp. 383-387
    • Rasmussen, S.G.1    Choi, H.J.2    Rosenbaum, D.M.3    Al, E.4
  • 168
    • 0024294018 scopus 로고
    • The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain
    • Reneke JE, Blumer KJ, Courchesne WE Thorner J (1988) The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain. Cell 55 : 221 234.
    • (1988) Cell , vol.55 , pp. 221-234
    • Reneke, J.E.1    Blumer, K.J.2    Courchesne, W.E.3    Thorner, J.4
  • 169
    • 23344434987 scopus 로고    scopus 로고
    • The origin of multiple B mating specificities in Coprinus cinereus
    • Riquelme M, Challen MP, Casselton LA Brown AJ (2005) The origin of multiple B mating specificities in Coprinus cinereus. Genetics 170 : 1105 1119.
    • (2005) Genetics , vol.170 , pp. 1105-1119
    • Riquelme, M.1    Challen, M.P.2    Casselton, L.A.3    Brown, A.J.4
  • 170
    • 0344254753 scopus 로고    scopus 로고
    • Autocrine activation of the pheromone response pathway in matalpha2- cells is attenuated by SST2- and ASG7-dependent mechanisms
    • Rivers DM Sprague GF Jr. (2003) Autocrine activation of the pheromone response pathway in matalpha2- cells is attenuated by SST2- and ASG7-dependent mechanisms. Mol Genet Genomics 270 : 225 233.
    • (2003) Mol Genet Genomics , vol.270 , pp. 225-233
    • Rivers, D.M.1    Sprague Jr., G.F.2
  • 172
    • 0027943713 scopus 로고
    • Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor
    • Schandel KA Jenness DD (1994) Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor. Mol Cell Biol 14 : 7245 7255.
    • (1994) Mol Cell Biol , vol.14 , pp. 7245-7255
    • Schandel, K.A.1    Jenness, D.D.2
  • 173
    • 11144336583 scopus 로고    scopus 로고
    • Evidence for a role of the regulator of G-protein signaling protein CPRGS-1 in Galpha subunit CPG-1-mediated regulation of fungal virulence, conidiation, and hydrophobin synthesis in the chestnut blight fungus Cryphonectria parasitica
    • Segers GC, Regier JC Nuss DL (2004) Evidence for a role of the regulator of G-protein signaling protein CPRGS-1 in Galpha subunit CPG-1-mediated regulation of fungal virulence, conidiation, and hydrophobin synthesis in the chestnut blight fungus Cryphonectria parasitica. Eukaryot Cell 3 : 1454 1463.
    • (2004) Eukaryot Cell , vol.3 , pp. 1454-1463
    • Segers, G.C.1    Regier, J.C.2    Nuss, D.L.3
  • 174
    • 0036033424 scopus 로고    scopus 로고
    • Constitutive activity of G-protein-coupled receptors: Cause of disease and common property of wild-type receptors
    • Seifert R Wenzel-Seifert K (2002) Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors. Naunyn Schmiedebergs Arch Pharmacol 366 : 381 416.
    • (2002) Naunyn Schmiedebergs Arch Pharmacol , vol.366 , pp. 381-416
    • Seifert, R.1    Wenzel-Seifert, K.2
  • 175
    • 4644295583 scopus 로고    scopus 로고
    • The gprA and gprB genes encode putative G protein-coupled receptors required for self-fertilization in Aspergillus nidulans
    • Seo JA, Han KH Yu JH (2004) The gprA and gprB genes encode putative G protein-coupled receptors required for self-fertilization in Aspergillus
    • (2004) Mol Microbiol , vol.53 , pp. 1611-1623
    • Seo, J.A.1    Han, K.H.2    Yu, J.H.3
  • 176
    • 51649109166 scopus 로고    scopus 로고
    • The RGS protein Crg2 regulates pheromone and cAMP signaling in Cryptococcus neoformans
    • DOI:.
    • Shen G, Wang YL, Whittington A, Li L Wang P (2008) The RGS protein Crg2 regulates pheromone and cAMP signaling in Cryptococcus neoformans. Eukaryot Cell. DOI :.
    • (2008) Eukaryot Cell.
    • Shen, G.1    Wang, Y.L.2    Whittington, A.3    Li, L.4    Wang, P.5
  • 177
    • 35448979122 scopus 로고    scopus 로고
    • Rod1, an arrestin-related protein, is phosphorylated by Snf1-kinase in Saccharomyces cerevisiae
    • Shinoda J Kikuchi Y (2007) Rod1, an arrestin-related protein, is phosphorylated by Snf1-kinase in Saccharomyces cerevisiae. Biochem Biophys Res Commun 364 : 258 263.
    • (2007) Biochem Biophys Res Commun , vol.364 , pp. 258-263
    • Shinoda, J.1    Kikuchi, Y.2
  • 178
    • 25444528729 scopus 로고    scopus 로고
    • The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
    • Siderovski DP Willard FS (2005) The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits. Int J Biol Sci 1 : 51 66.
    • (2005) Int J Biol Sci , vol.1 , pp. 51-66
    • Siderovski, D.P.1    Willard, F.S.2
  • 179
    • 33745685061 scopus 로고    scopus 로고
    • Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome
    • Slessareva JE, Routt SM, Temple B, Bankaitis VA Dohlman HG (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126 : 191 203.
    • (2006) Cell , vol.126 , pp. 191-203
    • Slessareva, J.E.1    Routt, S.M.2    Temple, B.3    Bankaitis, V.A.4    Dohlman, H.G.5
  • 180
    • 0038058808 scopus 로고    scopus 로고
    • Three mating type-like loci in Candida glabrata
    • Srikantha T, Lachke SA Soll DR (2003) Three mating type-like loci in Candida glabrata. Eukaryot Cell 2 : 328 340.
    • (2003) Eukaryot Cell , vol.2 , pp. 328-340
    • Srikantha, T.1    Lachke, S.A.2    Soll, D.R.3
  • 181
    • 0031941108 scopus 로고    scopus 로고
    • Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors
    • Stefan CJ, Overton MC Blumer KJ (1998) Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors. Mol Biol Cell 9 : 885 899.
    • (1998) Mol Biol Cell , vol.9 , pp. 885-899
    • Stefan, C.J.1    Overton, M.C.2    Blumer, K.J.3
  • 182
    • 0027391510 scopus 로고
    • Schizosaccharomyces pombe map3+ encodes the putative M-factor receptor
    • Tanaka K, Davey J, Imai Y Yamamoto M (1993) Schizosaccharomyces pombe map3+ encodes the putative M-factor receptor. Mol Cell Biol 13 : 80 88.
    • (1993) Mol Cell Biol , vol.13 , pp. 80-88
    • Tanaka, K.1    Davey, J.2    Imai, Y.3    Yamamoto, M.4
  • 184
    • 0031603760 scopus 로고    scopus 로고
    • A function for monoubiquitination in the internalization of a G protein-coupled receptor
    • Terrell J, Shih S, Dunn R Hicke L (1998) A function for monoubiquitination in the internalization of a G protein-coupled receptor. Mol Cell 1 : 193 202.
    • (1998) Mol Cell , vol.1 , pp. 193-202
    • Terrell, J.1    Shih, S.2    Dunn, R.3    Hicke, L.4
  • 185
    • 0030982264 scopus 로고    scopus 로고
    • Structure of RGS4 bound to AlF4-activated G(i alpha1): Stabilization of the transition state for GTP hydrolysis
    • Tesmer JJ, Berman DM, Gilman AG Sprang SR (1997) Structure of RGS4 bound to AlF4-activated G(i alpha1): stabilization of the transition state for GTP hydrolysis. Cell 89 : 251 261.
    • (1997) Cell , vol.89 , pp. 251-261
    • Tesmer, J.J.1    Berman, D.M.2    Gilman, A.G.3    Sprang, S.R.4
  • 186
    • 33645084249 scopus 로고    scopus 로고
    • Oxylipins act as determinants of natural product biosynthesis and seed colonization in Aspergillus nidulans
    • Tsitsigiannis DI Keller NP (2006) Oxylipins act as determinants of natural product biosynthesis and seed colonization in Aspergillus nidulans. Mol Microbiol 59 : 882 892.
    • (2006) Mol Microbiol , vol.59 , pp. 882-892
    • Tsitsigiannis, D.I.1    Keller, N.P.2
  • 187
    • 33847639239 scopus 로고    scopus 로고
    • Oxylipins as developmental and host-fungal communication signals
    • Tsitsigiannis DI Keller NP (2007) Oxylipins as developmental and host-fungal communication signals. Trends Microbiol 15 : 109 118.
    • (2007) Trends Microbiol , vol.15 , pp. 109-118
    • Tsitsigiannis, D.I.1    Keller, N.P.2
  • 188
    • 23344437309 scopus 로고    scopus 로고
    • Aspergillus cyclooxygenase-like enzymes are associated with prostaglandin production and virulence
    • Tsitsigiannis DI, Bok JW, Andes D, Nielsen KF, Frisvad JC Keller NP (2005a) Aspergillus cyclooxygenase-like enzymes are associated with prostaglandin production and virulence. Infect Immun 73 : 4548 4559.
    • (2005) Infect Immun , vol.73 , pp. 4548-4559
    • Tsitsigiannis, D.I.1    Bok, J.W.2    Andes, D.3    Nielsen, K.F.4    Frisvad, J.C.5    Keller, N.P.6
  • 189
    • 21344467963 scopus 로고    scopus 로고
    • Three putative oxylipin biosynthetic genes integrate sexual and asexual development in Aspergillus nidulans
    • Tsitsigiannis DI, Kowieski TM, Zarnowski R Keller NP (2005b) Three putative oxylipin biosynthetic genes integrate sexual and asexual development in Aspergillus nidulans. Microbiology 151 : 1809 1821.
    • (2005) Microbiology , vol.151 , pp. 1809-1821
    • Tsitsigiannis, D.I.1    Kowieski, T.M.2    Zarnowski, R.3    Keller, N.P.4
  • 191
    • 0033569790 scopus 로고    scopus 로고
    • A novel regulator of G protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2
    • Versele M, de Winde JH Thevelein JM (1999) A novel regulator of G protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2. EMBO J 18 : 5577 5591.
    • (1999) EMBO J , vol.18 , pp. 5577-5591
    • Versele, M.1    De Winde, J.H.2    Thevelein, J.M.3
  • 192
    • 0034894495 scopus 로고    scopus 로고
    • Sex and sugar in yeast: Two distinct GPCR systems
    • Versele M, Lemaire K Thevelein JM (2001) Sex and sugar in yeast: two distinct GPCR systems. EMBO Rep 2 : 574 579.
    • (2001) EMBO Rep , vol.2 , pp. 574-579
    • Versele, M.1    Lemaire, K.2    Thevelein, J.M.3
  • 193
    • 0033178303 scopus 로고    scopus 로고
    • Signal transduction cascades regulating mating, filamentation, and virulence in Cryptococcus neoformans
    • Wang P Heitman J (1999) Signal transduction cascades regulating mating, filamentation, and virulence in Cryptococcus neoformans. Curr Opin Microbiol 2 : 358 362.
    • (1999) Curr Opin Microbiol , vol.2 , pp. 358-362
    • Wang, P.1    Heitman, J.2
  • 194
    • 4143110145 scopus 로고    scopus 로고
    • Mutation of the regulator of G protein signaling Crg1 increases virulence in Cryptococcus neoformans
    • Wang P, Cutler J, King J Palmer D (2004) Mutation of the regulator of G protein signaling Crg1 increases virulence in Cryptococcus neoformans. Eukaryot Cell 3 : 1028 1035.
    • (2004) Eukaryot Cell , vol.3 , pp. 1028-1035
    • Wang, P.1    Cutler, J.2    King, J.3    Palmer, D.4
  • 195
    • 18744369621 scopus 로고    scopus 로고
    • Leptosphaeria rhodopsin: Bacteriorhodopsin-like proton pump from a eukaryote
    • Waschuk SA, Bezerra AG Jr., Shi L Brown LS (2005) Leptosphaeria rhodopsin: bacteriorhodopsin-like proton pump from a eukaryote. Proc Natl Acad Sci USA 102 : 6879 6883.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 6879-6883
    • Waschuk, S.A.1    Bezerra Jr., A.G.2    Shi, L.3    Brown, L.S.4
  • 196
    • 0033786755 scopus 로고    scopus 로고
    • Glucose monitoring in fission yeast via the Gpa2 Galpha, the Git5 Gbeta and the Git3 putative glucose receptor
    • Welton RM Hoffman CS (2000) Glucose monitoring in fission yeast via the Gpa2 Galpha, the Git5 Gbeta and the Git3 putative glucose receptor. Genetics 156 : 513 521.
    • (2000) Genetics , vol.156 , pp. 513-521
    • Welton, R.M.1    Hoffman, C.S.2
  • 197
    • 0024966029 scopus 로고
    • The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein
    • Whiteway M, Hougan L, Dignard D, Thomas DY, Bell L, Saari GC, Grant FJ, O'Hara P MacKay VL (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56 : 467 477.
    • (1989) Cell , vol.56 , pp. 467-477
    • Whiteway, M.1    Hougan, L.2    Dignard, D.3    Thomas, D.Y.4    Bell, L.5    Saari, G.C.6    Grant, F.J.7    O'Hara, P.8    MacKay, V.L.9
  • 198
  • 199
    • 33947119230 scopus 로고    scopus 로고
    • Regulators of G protein signalling: A spotlight on emerging functions in the cardiovascular system
    • Wieland T, Lutz S Chidiac P (2007) Regulators of G protein signalling: a spotlight on emerging functions in the cardiovascular system. Curr Opin Pharmacol 7 : 201 207.
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 201-207
    • Wieland, T.1    Lutz, S.2    Chidiac, P.3
  • 200
    • 0031437841 scopus 로고    scopus 로고
    • Measurement of agonist efficacy using an alpha2A-adrenoceptor-Gi1alpha fusion protein
    • Wise A, Carr IC, Groarke DA Milligan G (1997) Measurement of agonist efficacy using an alpha2A-adrenoceptor-Gi1alpha fusion protein. FEBS Lett 419 : 141 146.
    • (1997) FEBS Lett , vol.419 , pp. 141-146
    • Wise, A.1    Carr, I.C.2    Groarke, D.A.3    Milligan, G.4
  • 202
    • 0029846423 scopus 로고    scopus 로고
    • MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea
    • Xu JR Hamer JE (1996) MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes Dev 10 : 2696 2706.
    • (1996) Genes Dev , vol.10 , pp. 2696-2706
    • Xu, J.R.1    Hamer, J.E.2
  • 203
    • 31944437746 scopus 로고    scopus 로고
    • G protein-coupled receptor Gpr4 senses amino acids and activates the cAMP-PKA pathway in Cryptococcus neoformans
    • Xue C, Bahn YS, Cox GM Heitman J (2006) G protein-coupled receptor Gpr4 senses amino acids and activates the cAMP-PKA pathway in Cryptococcus neoformans. Mol Biol Cell 17 : 667 679.
    • (2006) Mol Biol Cell , vol.17 , pp. 667-679
    • Xue, C.1    Bahn, Y.S.2    Cox, G.M.3    Heitman, J.4
  • 204
    • 34249882487 scopus 로고    scopus 로고
    • The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants
    • Xue C, Tada Y, Dong X Heitman J (2007) The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants. Cell Host Microbe 1 : 263 273.
    • (2007) Cell Host Microbe , vol.1 , pp. 263-273
    • Xue, C.1    Tada, Y.2    Dong, X.3    Heitman, J.4
  • 205
    • 52649135641 scopus 로고    scopus 로고
    • The RGS protein Crg2 coordinates pheromone and cAMP signaling in Cryptococcus neoformans
    • DOI:.
    • Xue C, Hsueh Y, Chen L Heitman J (2008) The RGS protein Crg2 coordinates pheromone and cAMP signaling in Cryptococcus neoformans. Mol Microbiol DOI :.
    • (2008) Mol Microbiol
    • Xue, C.1    Hsueh, Y.2    Chen, L.3    Heitman, J.4
  • 206
    • 0032055105 scopus 로고    scopus 로고
    • GPR1 encodes a putative G protein-coupled receptor that associates with the Gpa2p Galpha subunit and functions in a Ras-independent pathway
    • Xue Y, Batlle M Hirsch JP (1998) GPR1 encodes a putative G protein-coupled receptor that associates with the Gpa2p Galpha subunit and functions in a Ras-independent pathway. EMBO J 17 : 1996 2007.
    • (1998) EMBO J , vol.17 , pp. 1996-2007
    • Xue, Y.1    Batlle, M.2    Hirsch, J.P.3
  • 207
    • 0034492374 scopus 로고    scopus 로고
    • Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis
    • Yesilaltay A Jenness DD (2000) Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis. Mol Biol Cell 11 : 2873 2884.
    • (2000) Mol Biol Cell , vol.11 , pp. 2873-2884
    • Yesilaltay, A.1    Jenness, D.D.2
  • 208
    • 41649086736 scopus 로고    scopus 로고
    • The same receptor, G Protein, and mitogen-activated protein kinase pathway activate different downstream regulators in the alternative white and opaque pheromone responses of Candida albicans
    • Yi S, Sahni N, Daniels KJ, Pujol C, Srikantha T Soll DR (2008) The same receptor, G Protein, and mitogen-activated protein kinase pathway activate different downstream regulators in the alternative white and opaque pheromone responses of Candida albicans. Mol Biol Cell 19 : 957 970.
    • (2008) Mol Biol Cell , vol.19 , pp. 957-970
    • Yi, S.1    Sahni, N.2    Daniels, K.J.3    Pujol, C.4    Srikantha, T.5    Soll, D.R.6
  • 209
    • 2442716363 scopus 로고    scopus 로고
    • Probing receptor structure/function with chimeric G-protein-coupled receptors
    • Yin D, Gavi S, Wang HY Malbon CC (2004) Probing receptor structure/function with chimeric G-protein-coupled receptors. Mol Pharmacol 65 : 1323 1332.
    • (2004) Mol Pharmacol , vol.65 , pp. 1323-1332
    • Yin, D.1    Gavi, S.2    Wang, H.Y.3    Malbon, C.C.4
  • 210
    • 33745766927 scopus 로고    scopus 로고
    • Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans
    • Yu JH (2006) Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans. J Microbiol 44 : 145 154.
    • (2006) J Microbiol , vol.44 , pp. 145-154
    • Yu, J.H.1
  • 211
    • 0029790622 scopus 로고    scopus 로고
    • The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development
    • Yu JH, Wieser J Adams TH (1996) The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development. EMBO J 15 : 5184 5190.
    • (1996) EMBO J , vol.15 , pp. 5184-5190
    • Yu, J.H.1    Wieser, J.2    Adams, T.H.3
  • 212
    • 0026493590 scopus 로고
    • Yeast pheromone receptor endocytosis and hyperphosphorylation are independent of G protein-mediated signal transduction
    • Zanolari B, Raths S, Singer-Kruger B Riezman H (1992) Yeast pheromone receptor endocytosis and hyperphosphorylation are independent of G protein-mediated signal transduction. Cell 71 : 755 763.
    • (1992) Cell , vol.71 , pp. 755-763
    • Zanolari, B.1    Raths, S.2    Singer-Kruger, B.3    Riezman, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.