A seven-transmembrane RGS protein that modulates plant cell proliferation

Science

Volumn 301, Issue 5640, 2003, Pages 1728-1731

  Chen, Jin Gui ^a   Willard, Francis S ^b   Huang, Jirong ^a   Liang, Jiansheng ^a,c   Chasse, Scott A ^b   Jones, Alan M ^a   Siderovski, David P ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c YANGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; PROTEINS;

PROTEIN-COUPLED RECEPTORS;

PLANT CELL CULTURE;

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; MUTANT PROTEIN; PROTEIN SUBUNIT; PYROPHOSPHATE; RGS PROTEIN;

BIOLOGY; PLANT; PROTEIN;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARTICLE; CELL ELONGATION; CELL MEMBRANE; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; LIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHYTOCHEMISTRY; PLANT CELL; PLANT GROWTH; PLANT ROOT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; ROOT GROWTH; SIGNAL TRANSDUCTION; YEAST;

ALLELES; AMINO ACID SEQUENCE; ARABIDOPSIS; ARABIDOPSIS PROTEINS; CELL DIFFERENTIATION; CELL DIVISION; CELL MEMBRANE; GTP-BINDING PROTEIN ALPHA SUBUNITS; HETEROTRIMERIC GTP-BINDING PROTEINS; MERISTEM; MITOSIS; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; PHENOTYPE; PLANT ROOTS; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RGS PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSGENES;

ARABIDOPSIS;

EID: 0141431978     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1087790     Document Type: Article

References (21)

1. H. E. Hamm, J. Biol. Chem. 273, 669 (1998).
2. R. R. Neubig, D. P. Siderovski. Nature Rev. Drug Discov. 1, 187 (2002).
3. A. M. Jones, Curr. Opin. Plant Biol. 5, 402 (2002).
4. S. M. Assmann, Plant Cell Suppl. 14, 5355 (2002).
5. H. Ullah et al., Science 292, 2066 (2001).
6. H. Ullah et al., Plant Cell 15, 393 (2003).
7. Materials and methods are provided as supplemental materials on Science Online.
8. -1 as described by A. Bateman et al. [Nucleic Acids Res. 30, 276 (2002)].
9. U. Gether, Endocrine Rev. 21, 90 (2000).
10. J. J. Tesmer, D. M. Berman, A. G. Gilman, S. R. Sprang, Cell 89, 251 (1997).
11. H. G. Dohlman, J. Song, D. Ma, W. E. Courchesne, J. Thorner, Mol. Biol. Cell 16, 5194 (1996).
12. I. Stagljar, C. Korostensky, N. Johnsson, S. te Heesen, Proc. Natl. Acad. Sci. U.S.A. 95, 5187 (1998).
13. H. Huang, C. Weiss, H. Ma, Int. J. Plant Sci. 155, 3 (1994).
14. A. M. Jones, J. R. Ecker, J. G. Chen, Plant Physiol. 131, 1623 (2003).
15. A. Krogh, B. Larsson, G. von Heijne, E. L. L. Sonnhammer, J. Mol. Biol. 305, 567 (2001).
16. J. D. Thompson, T. J. Gibson, F. Plewniak, F. Jeanmougin, D. G. Higgins, Nucleic Acids Res. 24, 4876 (1997).
17. E. de Alba, L. De Vries, M. G. Farquhar, N. Tjandra, J. Mol. Biol. 291, 927 (1999).
18. L. J. McGuffin, K. Bryson, D. T. Jones, Bioinformatics 16, 404 (1999).
19. R. J. Kimple et al., Comb. Chem. High Throughput Screen. 6, 399 (2003).
20. M. C. Kim et al., Nature 416, 447 (2002).
21. We thank H. G. Dohlman for comments on the manuscript, R. Panstruga (Max Planck Institüt Köln), C. Koncz (Max-Planck Institüt für Züchtungsforschung-Köln), and N.-H. Chua (Rockefeller University) for materials and technical assistance. Work in A.M.J.'s lab is supported by the National Institute of General Medical Sciences (GM65989) and NSF (0209711). D.P.S. is supported by a Year 2000 Neuroscience Scholarship from the EJLB Foundation, a Burroughs-Wellcome Fund New Investigator Award in the Pharmacological Sciences, and grants from NIGMS (GM62338 and GM65533). S.C. is supported by a grant from the NIH (GM055316) to H. Dohlman. J.L. is supported, in part, by the Chinese Key National Basic Research and Development Program.