Single Amino Acid Substitutions and Deletions That Alter the G Protein Coupling Properties of the V2 Vasopressin Receptor Identified in Yeast by Receptor Random Mutagenesis

Journal of Biological Chemistry

Volumn 276, Issue 31, 2001, Pages 29382-29392

  Erlenbach, Isolde ^a   Kostenis, Evi ^a   Schmidt, Clarice ^a   Serradeil Le Gal, Claudine ^b   Raufaste, Danielle ^b   Dumont, Mark E ^c   Pausch, Mark H ^d   Wess, Jürgen ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b SANOFI   (France)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CELLS; MUTAGENESIS; YEAST;

MUTANTS;

PROTEINS;

AMINO ACID; ARGININE; G PROTEIN COUPLED RECEPTOR; METHIONINE; PROTEIN SUBUNIT; VASOPRESSIN RECEPTOR; ARGIPRESSIN; GPA1 PROTEIN, S CEREVISIAE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; OLIGODEOXYRIBONUCLEOTIDE; PRIMER DNA; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; HUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; YEAST; ANIMAL; CATTLE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENE DELETION; GENE LIBRARY; GENETICS; GROWTH, DEVELOPMENT AND AGING; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ARGININE VASOPRESSIN; BASE SEQUENCE; CATTLE; CELL MEMBRANE; CLONING, MOLECULAR; DNA PRIMERS; GENE LIBRARY; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; RECEPTORS, VASOPRESSIN; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035800798     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103203200     Document Type: Article

References (52)

1. Dohlman, H. G., Thorner, J., Caron, M. G., and Lefkowitz, R. J. (1991) Annu. Rev. Biochem. 60, 653-688
2. Strader, C. D., Fong, T. M., Tota, M. R., Underwood, D., and Dixon, R. A. F. (1994) Annu. Rev. Biochem. 63, 101-132
3. Gudermann, T., Kalkbrenner, F., and Schultz, G. (1996) Annu. Rev. Pharmacol. Toxicol. 36, 429-459
4. Wess, J. (1998) Pharmacol. Ther. 80, 231-264
5. Wess, J. (1997) FASEB J. 11, 346-354
6. Pausch, M. H., Price, L. A., Kajkowski, E. M., Strnad, J., dela Cruz, F., Heinrich, J., Ozenberger, B. A., and Hadcock, J. R. (1998) in Identification and Expression of G Protein-Coupled Receptors (Lynch, K. R., ed) pp. 196-212, Wiley-Liss, New York
7. King, K., Dohlman, H. G., Thorner, J., Caron, M. G., and Lefkowitz, R. J. (1990) Science 250, 121-123
8. Price, L. A., Kajkowski, E. M., Hadcock, J. R., Ozenberger, B. A., and Pausch, M. H. (1995) Mol. Cell. Biol. 15, 6188-6195
9. Price, L., Strnad, J., Pausch, M., and Hadcock, J. (1996) Mol. Pharmacol. 50, 829-937
10. Kajkowski, E. M., Price, L. A., Pausch, M. H., Young, K. H., and Ozenberger, B. A. (1997) J. Recept. Signal Transduct. Res. 17, 293-303
11. Erickson, J. R., Wu, J. J., Goddard, J. G., Tigyi, G., Kawanishi, K., Tomei, L. D., and Kiefer, M. C. (1998) J. Biol. Chem. 273, 1506-1510
12. Brown, A. J., Dyos, S. L., Whiteway, M. S., White, J. H., Watson, M. A., Marzioch, M., Clare, J. J., Cousens, D. J., Paddon, C., Plumpton, C., Romanos, M. A., and Dowell, S. J. (2000) Yeast 16, 11-22
13. Swift, S., Sheridan, P. J., Covic, L., and Kuliopulos, A. (2000) J. Biol. Chem. 275, 2627-2635
14. Baranski, T. J., Herzmark, P., Lichtarge, O., Gerber, B. O., Trueheart, J., Meng, E. C., Iiri, T., Sheikh, S. P., and Bourne, H. R. (1999) J. Biol. Chem. 274, 15757-15765
15. Geva, A., Lassere, T. B., Lichtarge, O., Pollitt, S. K., and Baranski, T. J. (2000) J. Biol. Chem. 275, 35393-35401
16. Erlenbach, I., Kostenis, E., Schmidt, C., Hamdan, F. F., Pausch, M. H., and Wess, J. (2001) J. Neurochem. 77, 1327-1337
17. Birnbaumer, M., Seibold, A., Gilbert, S., Ishido, M., Barberis, C., Antaramian, A., Brabet, P., and Rosenthal, W. (1992) Nature 357, 333-335
18. Lolait, S. J., O'Carroll, A.-M., McBride, O. W., Konig, M., Morel, A., and Brownstein, M. J. (1992) Nature 357, 336-339
19. Burbach, J. P. H., Adan, R. A. H., Lolait, S. J., van Leeuwen, F. W., Mezey, E., Palkovits, M., and Barberis, C. (1995) Cell. Mol. Neurobiol. 15, 573-595
20. Thibonnier, M., Berti-Mattera, L. N., Dulin, N., Conarty, D. M., and Mattera, R. (1998) Prog. Brain Res. 119, 147-161
21. Liu, J., and Wess, J. (1996) J. Biol. Chem. 270, 8772-8778
22. Erlenbach, I., and Wess, J. (1998) J. Biol. Chem. 273, 26549-26558
23. Serradeil-Le Gal, C., Lacour, C., Valette, G., Garcia, G., Foulon, L., Galindo, G., Bankir, L., Pouzet, B., Guillon, G., Barberis, C., Chicot, D., Jard, S., Vilain, P., Garcia, C., Marty, E., Raufaste, D., Brossard, G., Nisato, D., Maffrand, J. P., and Le Fur, G. (1996) J. Clin. Invest. 98, 2729-2738
24. Serradeil-Le Gal, C., Raufaste, D., Double-Cazanave, E., Guillon, G., Garcia, C., Pascal, M., and Maffrand, J. P. (2000) Kidney Int. 58, 1613-1622
25. Schöneberg, T., Yun, J., Wenkert, D., and Wess, J. (1996) EMBO J. 15, 1283-1291
26. Mumberg, D., Müller, R., and Funk, M. (1995) Gene 156, 119-122
27. Christianson, T. W., Sikorski, R. S., Dante, M., Shero, J. H., and Hieter, P. (1992) Gene 110, 119-122
28. Gietz, R. D., and Woods, R. A. (1994) in Molecular Genetics of Yeast: Practical Approaches (Johnston, J. A., ed) pp. 124-134, Oxford University Press, Oxford
29. Muhlrad, D., Hunter, R., and Parker, R. (1992) Yeast 8, 79-82
30. Staples, R. R., and Dieckmann, C. L. (1993) Genetics 135, 981-991
31. Sommers, C. M., and Dumont, M. E. (1997) J. Mol. Biol. 266, 559-575
32. Sommers, C. M., and Dumont, M. E. (1999) in Structure-Function Analysis of G Protein-Coupled Receptors (Wess, J., ed) pp. 141-166, Wiley-Liss, New York
33. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
34. Munson, P. J., and Rodbard, D. (1980) Anal. Biochem. 107, 220-239
35. Zhu, X., and Wess, J. (1998) Biochemistry 37, 15773-15784
36. Innamorati, G., Sadeghi, H., and Birnbaumer, M. (1996) Mol. Pharmacol. 50, 467-473
37. Romanos, M. A., Scorer, C. A., and Clare, J. J. (1992) Yeast 8, 423-488
38. Yun, J., Schöneberg, T., Liu, J., Schulz, A., Ecelbarger, C. A., Promeneur, D., Nielsen, S., Sheng, H., Grinberg, A., Deng, C., and Wess, J. (2000) J. Clin. Invest. 106, 1361-1371
39. Conklin, B. R., Farfel, Z., Lustig, K. D., Julius, D., and Bourne, H. R. (1993) Nature 363, 274-276
40. Liu, J., Conklin, B. R., Blin, N., Yun., J., and Wess, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11642-11646
41. Conklin, B. R., and Bourne, H. R. (1993) Cell 73, 631-641
42. Rens-Domiano, S., and Hamm, H. (1995) FASEB J. 9, 1059-1066
43. Kostenis, E., Gomeza, J., Lerche, C., and Wess, J. (1997) J. Biol. Chem. 272, 23675-23681
44. Kostenis, E., Conklin, B. R., and Wess, J. (1997) Biochemistry 36, 1487-1495
45. Acharya, S., Saad, Y., and Karnik, S. S. (1997) J. Biol. Chem. 272, 6519-6524
46. Moro, O., Lameh, J., Högger, P., and Sadée, W. (1993) J. Biol. Chem. 268, 22273-22276
47. Watson, S., and Arkinstall, S. (1994) in The G-Protein Linked Receptor-Facts Book (Watson, S., and Arkinstall, S., eds) pp. 1-291, Academic Press, London
48. Arora, K. K., Sakai, A., and Catt, K. J. (1995) J. Biol. Chem. 270, 22820-22826
49. Smit, M. J., Roovers, E., Timmerman, H., van de Vrede, Y., Alewijnse, A. E., and Leurs, R. (1996) J. Biol. Chem. 271, 7574-7582
50. Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., Yamamoto, M., Miyano, M. (2000) Science 289, 739-745
51. Nathans, J., and Hogness, D. S. (1983) Cell 34, 807-814
52. Morel, A., O'Carroll, A.-M., Brownstein, M. J., and Lolait, S. J. (1992) Nature 356, 523-526