-
1
-
-
0030949485
-
Markedly reduced activity of mutant calcium-sensing receptor with an inserted Alu element from a kindred with familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
-
Bai, M., N. Janicic, S. Trivedi, S. J. Quinn, D. E. Cole, E. M. Brown, and G. N. Hendy. 1997. Markedly reduced activity of mutant calcium-sensing receptor with an inserted Alu element from a kindred with familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. J. Clin. Investig. 99:1917-1925.
-
(1997)
J. Clin. Investig.
, vol.99
, pp. 1917-1925
-
-
Bai, M.1
Janicic, N.2
Trivedi, S.3
Quinn, S.J.4
Cole, D.E.5
Brown, E.M.6
Hendy, G.N.7
-
2
-
-
0027506471
-
The probable arrangement of the helices in G protein-coupled receptors
-
Baldwin, J. M. 1993, The probable arrangement of the helices in G protein-coupled receptors. EMBO J. 12:1693-1703.
-
(1993)
EMBO J.
, vol.12
, pp. 1693-1703
-
-
Baldwin, J.M.1
-
3
-
-
12044260162
-
Mutations that alter the third cytoplasmic loop of the a-factor receptor lead to a constitutive and hypersensitive phenotype
-
Boone, C., N. G. Davis, and G. F. Sprague, Jr. 1993. Mutations that alter the third cytoplasmic loop of the a-factor receptor lead to a constitutive and hypersensitive phenotype. Proc. Natl. Acad. Sci. USA 90:9921-9925.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9921-9925
-
-
Boone, C.1
Davis, N.G.2
Sprague Jr., G.F.3
-
4
-
-
0030987069
-
How receptors talk to trimeric G proteins
-
Bourne, H. R. 1997. How receptors talk to trimeric G proteins. Curr. Opin. Cell Biol. 9:134-142.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 134-142
-
-
Bourne, H.R.1
-
5
-
-
0022422406
-
The yeast α-factor receptor:structural properties deduced from the sequence of the STE2 gene
-
Burkholder, A. C., and L. H. Hartwell. 1985. The yeast α-factor receptor:structural properties deduced from the sequence of the STE2 gene. Nucleic Acids Res. 13:8463-8475.
-
(1985)
Nucleic Acids Res.
, vol.13
, pp. 8463-8475
-
-
Burkholder, A.C.1
Hartwell, L.H.2
-
6
-
-
0029656276
-
Regulation of the G-protein-coupled α-factor pheromone receptor by phosphorylation
-
Chen, Q., and J. B. Konopka. 1996. Regulation of the G-protein-coupled α-factor pheromone receptor by phosphorylation. Mol. Cell. Biol. 16:247-257.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 247-257
-
-
Chen, Q.1
Konopka, J.B.2
-
7
-
-
0028286250
-
Systematic mutagenesis of the yeast mating pheromone receptor third intracellular loop
-
Clark, C. D., T. Palzkill, and D. Botstein. 1994. Systematic mutagenesis of the yeast mating pheromone receptor third intracellular loop. J. Biol. Chem. 269:8831-8841.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8831-8841
-
-
Clark, C.D.1
Palzkill, T.2
Botstein, D.3
-
8
-
-
0028230817
-
Expanding horizons for receptors coupled to G proteins:diversity and disease
-
Coughlin, S. 1994. Expanding horizons for receptors coupled to G proteins:diversity and disease. Curr. Opin. Cell Biol. 6:191-197.
-
(1994)
Curr. Opin. Cell Biol.
, vol.6
, pp. 191-197
-
-
Coughlin, S.1
-
9
-
-
0029894423
-
1 arrest response in cells expressing an inappropriate pheromone receptor
-
1 arrest response in cells expressing an inappropriate pheromone receptor. Mol. Cell. Biol. 16:4478-4485.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4478-4485
-
-
Couve, A.1
Hirsch, J.P.2
-
10
-
-
0025812324
-
Model systems for the study of 7-transmembrane-segment receptors
-
Dohlman, H. G., J. Thorner, M. G. Caron, and R. J. Lefkowitz. 1991. Model systems for the study of 7-transmembrane-segment receptors. Annu. Rev. Biochem. 60:653-688.
-
(1991)
Annu. Rev. Biochem.
, vol.60
, pp. 653-688
-
-
Dohlman, H.G.1
Thorner, J.2
Caron, M.G.3
Lefkowitz, R.J.4
-
11
-
-
0028800729
-
Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor
-
Elling, C. E., S. M. Nielsen, and T. W. Schwartz. 1995. Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor. Nature 374:74-77.
-
(1995)
Nature
, vol.374
, pp. 74-77
-
-
Elling, C.E.1
Nielsen, S.M.2
Schwartz, T.W.3
-
12
-
-
0024266139
-
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
-
Gietz, R. D., and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534.
-
(1988)
Gene
, vol.74
, pp. 527-534
-
-
Gietz, R.D.1
Sugino, A.2
-
13
-
-
0031446639
-
Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor
-
Grosse, R., T. Schoneberg, G. Schultz, and T. Gudermann. 1997. Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor. Mol. Endocrinol. 11:1305-1318.
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 1305-1318
-
-
Grosse, R.1
Schoneberg, T.2
Schultz, G.3
Gudermann, T.4
-
14
-
-
0022730595
-
Multiple regulation of STE2, a mating-type-specific gene of Saccharomyces cerevisiae
-
Hartig, A., J. Holly, G. Saari, and V. L. MacKay. 1986. Multiple regulation of STE2, a mating-type-specific gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 6:2106-2114.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 2106-2114
-
-
Hartig, A.1
Holly, J.2
Saari, G.3
MacKay, V.L.4
-
17
-
-
0030054178
-
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis
-
Hicke, L., and H. Riezman. 1996. Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84:277-287.
-
(1996)
Cell
, vol.84
, pp. 277-287
-
-
Hicke, L.1
Riezman, A.H.2
-
18
-
-
0026058365
-
A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization
-
Kashles, O., Y. Yarden, R. Fischer, A. Ullrich, and J. Schlessinger. 1991. A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization. Mol. Cell. Biol. 11:1454-1463.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1454-1463
-
-
Kashles, O.1
Yarden, Y.2
Fischer, R.3
Ullrich, A.4
Schlessinger, J.5
-
20
-
-
0026178033
-
Genetic fine-structural analysis of the Saccharomyces cerevisiae α-pheromone receptor
-
Konopka, J. B., and D. D. Jenness. 1991. Genetic fine-structural analysis of the Saccharomyces cerevisiae α-pheromone receptor. Cell Regul. 2:439-452.
-
(1991)
Cell Regul.
, vol.2
, pp. 439-452
-
-
Konopka, J.B.1
Jenness, D.D.2
-
21
-
-
0023724429
-
The C terminus of the Saccharomyces cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
-
Konopka, J. B., D. D. Jenness, and L. H. Hartwell. 1988. The C terminus of the Saccharomyces cerevisiae α-pheromone receptor mediates an adaptive response to pheromone. Cell 54:609-620.
-
(1988)
Cell
, vol.54
, pp. 609-620
-
-
Konopka, J.B.1
Jenness, D.D.2
Hartwell, L.H.3
-
22
-
-
0029900790
-
Mutation of pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled α-factor receptor
-
Konopka, J. B., M. Margarit, and P. Dube. 1996. Mutation of pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled α-factor receptor. Proc. Natl. Acad. Sci. USA 93:6764-6769.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6764-6769
-
-
Konopka, J.B.1
Margarit, M.2
Dube, P.3
-
23
-
-
0026073301
-
Classical mutagenesis techniques
-
Lawrence, C. W. 1991. Classical mutagenesis techniques. Methods Enzymol. 194:273-281.
-
(1991)
Methods Enzymol.
, vol.194
, pp. 273-281
-
-
Lawrence, C.W.1
-
25
-
-
0027494368
-
Turned on to ill effect
-
Lefkowitz, R. J. 1993. Turned on to ill effect. Nature 365:603-604.
-
(1993)
Nature
, vol.365
, pp. 603-604
-
-
Lefkowitz, R.J.1
-
26
-
-
0027297275
-
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
-
Lefkowitz, R. J., S. Cotecchia, P. Samama, and T. Costa. 1993. Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol. Sci. 14:303-307.
-
(1993)
Trends Pharmacol. Sci.
, vol.14
, pp. 303-307
-
-
Lefkowitz, R.J.1
Cotecchia, S.2
Samama, P.3
Costa, T.4
-
27
-
-
0027533276
-
Reconstitution of functional muscarinic receptors by co-expression of amino- and carboxyl-terminal receptor fragments
-
Maggio, R., Z. Vogel, and J. Wess. 1993. Reconstitution of functional muscarinic receptors by co-expression of amino- and carboxyl-terminal receptor fragments. FEBS Lett. 319:195-200.
-
(1993)
FEBS Lett.
, vol.319
, pp. 195-200
-
-
Maggio, R.1
Vogel, Z.2
Wess, J.3
-
28
-
-
0028860268
-
Heterotrimeric G proteins:organizers of transmembrane signals
-
Neer, E. J. 1995. Heterotrimeric G proteins:organizers of transmembrane signals. Cell 80:249-257.
-
(1995)
Cell
, vol.80
, pp. 249-257
-
-
Neer, E.J.1
-
29
-
-
0028840683
-
Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway
-
Price, L. A., E. M. Kajkowski, J. R. Hadcock, B. A. Ozenberger, and M. H. Pausen. 1995. Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. Mol. Cell. Biol. 15:6188-6195.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6188-6195
-
-
Price, L.A.1
Kajkowski, E.M.2
Hadcock, J.R.3
Ozenberger, B.A.4
Pausen, M.H.5
-
31
-
-
0027455339
-
End3 and end4:two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae
-
Raths, S., J. Rohrer, F. Crausaz, and H. Riezman. 1993. end3 and end4:two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae. J. Cell Biol. 120:55-65.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 55-65
-
-
Raths, S.1
Rohrer, J.2
Crausaz, F.3
Riezman, H.4
-
32
-
-
0024294018
-
The carboxyl terminal domain α-factor receptor is a regulatory domain
-
Reneke, J. E., K. J. Blumer, W. E. Courchesne, and J. Thorner. 1988. The carboxyl terminal domain α-factor receptor is a regulatory domain. Cell 55:221-234.
-
(1988)
Cell
, vol.55
, pp. 221-234
-
-
Reneke, J.E.1
Blumer, K.J.2
Courchesne, W.E.3
Thorner, J.4
-
33
-
-
0030600396
-
Follitropin signal transduction:alternative splicing of the FSH receptor gene produces a domainant negative form of receptor which inhibits hormone action
-
Sairam, M. R., L. G. Jiang, T. A. Yarney, and H. Khan. 1996. Follitropin signal transduction:alternative splicing of the FSH receptor gene produces a domainant negative form of receptor which inhibits hormone action. Biochem. Biophys. Res. Commun. 226:717-722.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.226
, pp. 717-722
-
-
Sairam, M.R.1
Jiang, L.G.2
Yarney, T.A.3
Khan, H.4
-
34
-
-
0027943713
-
Direct evidence for ligand-induced internalization of the yeast α-factor pheromone receptor
-
Schandel, K. A., and D. D. Jenness. 1994. Direct evidence for ligand-induced internalization of the yeast α-factor pheromone receptor. Mol. Cell. Biol. 14:7245-7255.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7245-7255
-
-
Schandel, K.A.1
Jenness, D.D.2
-
35
-
-
0029898348
-
Is there a 'lock' for all agonist 'keys' in 7TM receptors?
-
Schwartz, T. W., and M. M. Rosenkilde. 1996. Is there a 'lock' for all agonist 'keys' in 7TM receptors? Trends Pharmacol. Sci. 17:213-216.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, pp. 213-216
-
-
Schwartz, T.W.1
Rosenkilde, M.M.2
-
36
-
-
0028174038
-
Noncontiguous domains of the α-factor receptor of yeasts confer ligand specificity
-
Sen, M., and L. Marsh. 1994. Noncontiguous domains of the α-factor receptor of yeasts confer ligand specificity. J. Biol. Chem. 269:968-973.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 968-973
-
-
Sen, M.1
Marsh, L.2
-
37
-
-
0030902912
-
Two types of α-factor receptor determinants for pheromone specificity in the mating-incompatible yeasts S. cerevisiae and S. kluyveri
-
Sen, M., A. Shah, and L. Marsh. 1997. Two types of α-factor receptor determinants for pheromone specificity in the mating-incompatible yeasts S. cerevisiae and S. kluyveri. Curr. Genet. 31:235-240.
-
(1997)
Curr. Genet.
, vol.31
, pp. 235-240
-
-
Sen, M.1
Shah, A.2
Marsh, L.3
-
38
-
-
0030568847
-
Role of SST2 in modulating G protein-coupled receptor signaling
-
Shah, A., and L. Marsh. 1996. Role of SST2 in modulating G protein-coupled receptor signaling. Biochem. Biophys. Res. Commun. 226:242-246.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.226
, pp. 242-246
-
-
Shah, A.1
Marsh, L.2
-
39
-
-
0029778268
-
Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F
-
Sheikh, S. P., T. A. Zvyaga, O. Lichtarge, T. P. Sakmar, and H. R. Bourne. 1996. Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F. Nature 383:347-350.
-
(1996)
Nature
, vol.383
, pp. 347-350
-
-
Sheikh, S.P.1
Zvyaga, T.A.2
Lichtarge, O.3
Sakmar, T.P.4
Bourne, H.R.5
-
40
-
-
0025978949
-
Getting started with yeast
-
Sherman, F. 1991. Getting started with yeast. Methods Enzymol. 194:3-21.
-
(1991)
Methods Enzymol.
, vol.194
, pp. 3-21
-
-
Sherman, F.1
-
41
-
-
0031588691
-
Genetic interactions among the transmembrane domains of the G protein-coupled receptor encoded by the yeast STE2 gene
-
Sommers, C. M., and M. E. Dumont. 1997. Genetic interactions among the transmembrane domains of the G protein-coupled receptor encoded by the yeast STE2 gene. J. Mol. Biol. 266:559-575.
-
(1997)
J. Mol. Biol.
, vol.266
, pp. 559-575
-
-
Sommers, C.M.1
Dumont, M.E.2
-
42
-
-
0029963793
-
Defects in G protein-coupled signal transduction in human disease
-
Spiegel, A. M. 1995. Defects in G protein-coupled signal transduction in human disease. Annu. Rev. Physiol. 58:143-170.
-
(1995)
Annu. Rev. Physiol.
, vol.58
, pp. 143-170
-
-
Spiegel, A.M.1
-
43
-
-
0029941917
-
Mutations in G proteins and G protein-coupled receptors in endocrine disease
-
Spiegel, A. M. 1996. Mutations in G proteins and G protein-coupled receptors in endocrine disease. J. Clin. Endocrinol. Metab. 81:2434-2442.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 2434-2442
-
-
Spiegel, A.M.1
-
44
-
-
0028273467
-
The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization
-
Stefan, C. J., and K. J. Blumer. 1994. The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization. Mol. Cell. Biol. 14:3339-3349.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3339-3349
-
-
Stefan, C.J.1
Blumer, K.J.2
-
45
-
-
0031941108
-
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors
-
Stefan, C. J., M. C. Overton, and K. J. Blumer. 1998. Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors. Mol. Biol. Cell 9:885-899.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 885-899
-
-
Stefan, C.J.1
Overton, M.C.2
Blumer, K.J.3
-
46
-
-
0023376280
-
Two genes required for cell fusion during yeast conjugation:evidence for a pheromone-induced surface protein
-
Trueheart, J., J. D. Boeke, and G. R. Fink. 1987. Two genes required for cell fusion during yeast conjugation:evidence for a pheromone-induced surface protein. Mol. Cell. Biol. 7:2316-2328.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2316-2328
-
-
Trueheart, J.1
Boeke, J.D.2
Fink, G.R.3
-
47
-
-
0030775615
-
Arrangement of rhodopsin transmembrane α-helices
-
Unger, V. M., P. A. Hargrave, J. M. Baldwin, and G. F. Schertler. 1997. Arrangement of rhodopsin transmembrane α-helices. Nature 389:203-206.
-
(1997)
Nature
, vol.389
, pp. 203-206
-
-
Unger, V.M.1
Hargrave, P.A.2
Baldwin, J.M.3
Schertler, G.F.4
-
48
-
-
0003965352
-
-
Academic Press, Ltd., London, England
-
Watson, S., and S. Arkinstall. 1994. The G-protein linked receptor facts-book. Academic Press, Ltd., London, England.
-
(1994)
The G-protein Linked Receptor Facts-book
-
-
Watson, S.1
Arkinstall, S.2
-
49
-
-
0030938936
-
G-protein-coupled receptors:molecular mechanisms involved in receptor activation and selectivity of G-protein recognition
-
Wess, J. 1997. G-protein-coupled receptors:molecular mechanisms involved in receptor activation and selectivity of G-protein recognition. FASEB J. 11:346-354.
-
(1997)
FASEB J.
, vol.11
, pp. 346-354
-
-
Wess, J.1
-
50
-
-
0021455017
-
The structure of an antigenic determinant in a protein
-
Wilson, I. A., H. L. Niman, R. A. Houghten, A. R. Cherenson, M. L. Connolly, and R. A. Lerner. 1984. The structure of an antigenic determinant in a protein. Cell 37:767-778.
-
(1984)
Cell
, vol.37
, pp. 767-778
-
-
Wilson, I.A.1
Niman, H.L.2
Houghten, R.A.3
Cherenson, A.R.4
Connolly, M.L.5
Lerner, R.A.6
-
51
-
-
0029738872
-
Experimentally determined hydrophobicity scale for proteins at membrane interfaces
-
Wimley, W. C., and S. H. White. 1996. Experimentally determined hydrophobicity scale for proteins at membrane interfaces. Nat. Struct. Biol. 10:842-848.
-
(1996)
Nat. Struct. Biol.
, vol.10
, pp. 842-848
-
-
Wimley, W.C.1
White, S.H.2
|