Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal

Aging Cell

Volumn 4, Issue 5, 2005, Pages 257-271

  Ayyadevara, Srinivas ^a,b   Engle, Mark R ^a   Singh, Sharda P ^a   Dandapat, Abhijit ^a   Lichti, Cheryl F ^a   Beneš, Helen ^a   Shmookler Reis, Robert J ^a,b,c   Liebau, Eva ^d   Zimniak, Piotr ^a,c  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^d BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

4 hydroxynonenal; Aging; C. elegans; Longevity regulation; Molecular biology of aging; Oxidative stress; Stress resistance; Transgenes

Indexed keywords

4 HYDROXYNONENAL; COMPLEMENTARY DNA; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; PARAQUAT; 4-HYDROXY-2-NONENAL; ALDEHYDE; CAENORHABDITIS ELEGANS PROTEIN; GROWTH INHIBITOR; HYBRID PROTEIN; ISOENZYME;

AGING; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CELL LYSATE; CONTROLLED STUDY; DNA FLANKING REGION; GENE LOCATION; GENETIC STRAIN; HEAT SHOCK; LIFESPAN; LIPID PEROXIDATION; METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; STRESS; TRANSGENIC ANIMAL; ULTRAVIOLET RADIATION; ANIMAL; ANIMAL MODEL; GENETICS; LONGEVITY; OXIDATIVE STRESS; PHYSIOLOGY;

ANIMALIA; CAENORHABDITIS ELEGANS; MURINAE;

ALDEHYDES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; GLUTATHIONE TRANSFERASE; GROWTH INHIBITORS; ISOENZYMES; LIPID PEROXIDATION; LONGEVITY; MODELS, ANIMAL; OXIDATIVE STRESS; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS;

EID: 27744580715     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2005.00168.x     Document Type: Article

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