Possibility of selection against mtDNA mutations in tumors

Molecular Cancer

Volumn 4, Issue , 2005, Pages

  Khaidakov, M ^a   Reis, R J Shmookler ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

CANCER CELL; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL DIVISION; CLONAL VARIATION; DATA ANALYSIS; GENE LOCATION; GENETIC SUSCEPTIBILITY; HOMOPLASY; HUMAN; INCIDENCE; PUBLISHING; REVIEW; SOMATIC MUTATION; GENETIC SELECTION; GENETICS; MUTATION; NEOPLASM;

DNA, MITOCHONDRIAL; HUMANS; MUTATION; NEOPLASMS; SELECTION, GENETIC;

EID: 26844522359     PISSN: 14764598     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-4-36     Document Type: Review

References (28)

1. Attardi G: MtDNA mutations in aging and apoptosis. Biochem Biophys Res Commun 2003, 304:519-529.
2. Wei YH, Lee HC: Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp Biol Med (Maywood) 2002, 227:671-682.
3. Sherer TB, Betarbet R, Greenamyre JT: Environment, mitochondria, and Parkinson's disease. Neuroscientist 2002, 8:192-197.
4. Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, et al.: Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res 2002, 70:357-360.
5. Sudoyo H, Suryadi H, Sitorus N, Soegondo S, Pranoto A, Marzuki S: Mitochondrial genome and susceptibility to diabetes mellitus. Adv Exp Med Biol 2003, 531:19-36.
6. Carew JS, Huang P: Mitochondrial defects in cancer. Mol Cancer 2002, 1:9.
7. Chun-Yang F: personal communication.
8. Fliss MS, Usadel H, Caballero OL, Wu L, Buta MR, Eleff SM, et al.: Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 2000, 287:2017-2019.
9. He L, Luo L, Proctor SJ, Middleton PG, Blakely EL, Taylor RW, et al.: Somatic mitochondrial DNA mutations in adult-onset leukaemia. Leukemia 2003, 17:2487-2491.
10. Liu VW, Shi HH, Cheung AN, Chiu PM, Leung TW, Nagley P, et al.: High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas. Cancer Res 2001, 61:5998-6001.
11. Nagy A, Wilhelm M, Sukosd F, Ljungberg B, Kovacs G: Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas. Genes Chromosomes Cancer 2002, 35:256-260.
12. Parrella P, Xiao Y, Fliss M, Sanchez-Cespedes M, Mazzarelli P, Rinaldi M, et al.: Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. Cancer Res 2001, 61:7623-7626.
13. Tan DJ, Bai RK, Wong LJ: Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res 2002, 62:972-976.
14. Tan DJ, Chang J, Chen WL, Agress LJ, Yeh KT, Wang B, et al.: Somatic mitochondrial DNA mutations in oral cancer of betel quid chewers. Ann N Y Acad Sci 2004, 1011:310-316.
15. Wong LJ, Lueth M, Li XN, Lau CC, Vogel H: Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients. Cancer Res 2003, 63:3866-3871.
16. Hibi K, Nakayama H, Yamazaki T, Takase T, Taguchi M, Kasai Y, et al.: Detection of mitochondrial DNA alterations in primary tumors and corresponding serum of colorectal cancer patients. Int J Cancer 2001, 94:429-431.
17. Hibi K, Nakayama H, Yamazaki T, Takase T, Taguchi M, Kasai Y, et al.: Mitochondrial DNA alteration in esophageal cancer. Int J Cancer 2001, 92:319-321.
18. Miyazono F, Schneider PM, Metzger R, Warnecke-Eberz U, Baldus SE, Dienes HP, et al.: Mutations in the mitochondrial DNA D-Loop region occur frequently in adenocarcinoma in Barrett's esophagus. Oncogene 2002, 21:3780-3783.
19. Tamura G, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Sakata K, et al.: Mutations in mitochondrial control region DNA in gastric tumours of Japanese patients. Eur J Cancer 1999, 35:316-319.
20. Okochi O, Hibi K, Uemura T, Inoue S, Takeda S, Kaneko T, et al.: Detection of mitochondrial DNA alterations in the serum of hepatocellular carcinoma patients. Clin Cancer Res 2002, 8:2875-2878.
21. Polyak K, Li Y, Zhu H, Lengauer C, Willson JK, et al.: Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat Genet 1998, 20:291-293.
22. Michels JJ, Marnay J, Delozier T, Denoux Y, Chasle J: Proliferative activity in primary breast carcinomas is a salient prognostic factor. Cancer 2004, 100:455-464.
23. Coller HA, Bodyak ND, Khrapko K: Frequent intracellular clonal expansions of somatic mtDNA mutations. Ann NY Acad Sci 2002, 959:434-447.
24. Nekhaeva E, Bodyak ND, Kraytsberg Y, McGrath SB, Van Orsouw NJ: Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues. Proc Natl Acad Sci USA 2002, 99:5521-5526.
25. Coller HA, Khrapko K, Bodyak ND, Nekhaeva E, Herrero-Jimenez P, Thilly WG: High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat Genet 2001, 28:147-150.
26. Taylor RW, Barron MJ, Borthwick GM, Gospel A, Chinnery PF, Samuels DC, et al.: Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Invest 2003, 112:1351-1360.
27. Shin MG, Kajigaya S, Tarnowka M, McCoy JP Jr, Levin BC, Young NS: Mitochondrial DNA sequence heterogeneity in circulating normal human CD34 cells and granulocytes. Blood 2004, 103:4466-4477.
28. Bach SP, Renehan AG, Potten CS: Stem cells; the intestinal stem cell as a paradigm. Carcinogenesis 2000, 21:469-476.