The impact of mitochondrial DNA on human lifespan: A view from studies on centenarians

Biotechnology Journal

Volumn 3, Issue 6, 2008, Pages 740-749

  Salvioli, Stefano ^a,b   Capri, Miriam ^a   Santoro, Aurelia ^a   Raule, Nicola ^a   Sevini, Federica ^a   Lukas, Stella ^a   Lanzarini, Catia ^a   Monti, Daniela ^c   Passarino, Giuseppe ^d   Rose, Giuseppina ^d   De Benedictis, Giovanna ^d   Franceschi, Claudio ^a,b,e  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b ER GenTech Laboratory   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d UNIVERSITY OF CALABRIA   (Italy)

^e INRCA   (Italy)

Author keywords

Aging; Centenarians; Longevity; Mitochondrial DNA

Indexed keywords

AGE-RELATED; ANIMAL MODELS; CELL TYPES; GENETIC VARIABILITY; HIGH-THROUGHPUT TECHNOLOGIES; INDIVIDUAL (PSS 544-7); LABORATORY EXPERIMENTS; LIFE SPANS; MITOCHONDRIAL DNA (MTDNA); SINGLE CELL LEVEL;

DNA; GENES; HEALTH; MITOCHONDRIA; NUCLEIC ACIDS; ORGANIC ACIDS; SUGAR (SUCROSE);

ANIMAL CELL CULTURE;

CYTOSINE; MITOCHONDRIAL DNA; THYMINE;

CELL TYPE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GERM LINE; HETEROPLASMY; HIGH THROUGHPUT SCREENING; HUMAN; LIFESPAN; LONGEVITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SOMATIC MUTATION; AGED; BIOLOGICAL MODEL; GENETICS; MUTATION;

ANIMALIA;

AGED, 80 AND OVER; DNA, MITOCHONDRIAL; HUMANS; LONGEVITY; MODELS, GENETIC; MUTATION;

EID: 48949119164     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.200800046     Document Type: Review

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