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Volumn 79, Issue 3, 2006, Pages 469-480

Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA; PROSTAGLANDIN SYNTHASE; SUCCINATE DEHYDROGENASE;

EID: 33748643416     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/507132     Document Type: Article
Times cited : (359)

References (44)
  • 1
    • 0030968884 scopus 로고    scopus 로고
    • Sarcopenia: Origins and clinical relevance
    • Rosenberg IH (1997) Sarcopenia: origins and clinical relevance. J Nutr 127:9905-9915
    • (1997) J Nutr , vol.127 , pp. 9905-9915
    • Rosenberg, I.H.1
  • 2
    • 0023856536 scopus 로고
    • What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men
    • Lexell J, Taylor CC, Sjostrom M (1988) What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. J Neurol Sci 84:275-294
    • (1988) J Neurol Sci , vol.84 , pp. 275-294
    • Lexell, J.1    Taylor, C.C.2    Sjostrom, M.3
  • 3
    • 0032522560 scopus 로고    scopus 로고
    • Epidemiology of sarcopenia among the elderly in New Mexico
    • Baumgartner RN, Koehler KM, Gallanger D (1998) Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 147:755-763
    • (1998) Am J Epidemiol , vol.147 , pp. 755-763
    • Baumgartner, R.N.1    Koehler, K.M.2    Gallanger, D.3
  • 4
    • 0035127889 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting and oxidative damage in sarcopenia
    • Wanagat J, Cao Z, Pathare P, Aiken JM (2001) Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting and oxidative damage in sarcopenia. FASEB J 15:322-332
    • (2001) FASEB J , vol.15 , pp. 322-332
    • Wanagat, J.1    Cao, Z.2    Pathare, P.3    Aiken, J.M.4
  • 5
    • 0032528481 scopus 로고    scopus 로고
    • Age-related muscle atrophy does not affect all muscles and can partly be compensated by physical activity: An ultrasound study
    • Reimers CD, Harder T, Saxe H (1998) Age-related muscle atrophy does not affect all muscles and can partly be compensated by physical activity: an ultrasound study. J Neurol Sci 159:60-66
    • (1998) J Neurol Sci , vol.159 , pp. 60-66
    • Reimers, C.D.1    Harder, T.2    Saxe, H.3
  • 6
  • 7
    • 0026453491 scopus 로고
    • Thigh composition in young and elderly men determined by computed tomography
    • Overend TJ, Cunningham DA, Paterson DH, Lefcoe MS (1992) Thigh composition in young and elderly men determined by computed tomography. Clin Physiol 12:629-640
    • (1992) Clin Physiol , vol.12 , pp. 629-640
    • Overend, T.J.1    Cunningham, D.A.2    Paterson, D.H.3    Lefcoe, M.S.4
  • 8
    • 0023521471 scopus 로고
    • Effects of ageing on the total number of muscle fibers and motoneurons of the tibialis anterior and soleus muscles in the rat
    • Ishihara A, Naitoh H, Katsuta S (1987) Effects of ageing on the total number of muscle fibers and motoneurons of the tibialis anterior and soleus muscles in the rat. Brain Res 435:355-358
    • (1987) Brain Res , vol.435 , pp. 355-358
    • Ishihara, A.1    Naitoh, H.2    Katsuta, S.3
  • 9
    • 0029865510 scopus 로고    scopus 로고
    • Growth hormone supplementation increases skeletal muscle mass of old male Fischer 344/Brown Norway rats
    • Cartee GD, Bohn EE, Gibson BT, Farrar RP (1996) Growth hormone supplementation increases skeletal muscle mass of old male Fischer 344/Brown Norway rats. J Gerontol A Biol Sci Med Sci 51:B214-B219
    • (1996) J Gerontol A Biol Sci Med Sci , vol.51
    • Cartee, G.D.1    Bohn, E.E.2    Gibson, B.T.3    Farrar, R.P.4
  • 10
    • 0036089622 scopus 로고    scopus 로고
    • Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia
    • Bua EA, McKiernan SH, Wanagat J, McKenzie D, Aiken JM (2002) Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia. J Appl Physiol 92:2617-2624
    • (2002) J Appl Physiol , vol.92 , pp. 2617-2624
    • Bua, E.A.1    McKiernan, S.H.2    Wanagat, J.3    McKenzie, D.4    Aiken, J.M.5
  • 11
    • 2442711771 scopus 로고    scopus 로고
    • Early-onset caloric restriction conserves fiber number in aging skeletal muscle
    • McKiernan SH, Bua E, McGorray J, Aiken JM (2004) Early-onset caloric restriction conserves fiber number in aging skeletal muscle. FASEB J 18:580-581
    • (2004) FASEB J , vol.18 , pp. 580-581
    • McKiernan, S.H.1    Bua, E.2    McGorray, J.3    Aiken, J.M.4
  • 12
    • 0034691680 scopus 로고    scopus 로고
    • Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys
    • Lopez ME, VanZeeland NL, Dahl DB, Weindruch R, Aiken JM (2000) Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys. Mutation Res 452:123-138
    • (2000) Mutation Res , vol.452 , pp. 123-138
    • Lopez, M.E.1    VanZeeland, N.L.2    Dahl, D.B.3    Weindruch, R.4    Aiken, J.M.5
  • 13
    • 0026732706 scopus 로고
    • Pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
    • Cortopassi GA, Shibata D, Soong NW, Arnheim NA (1992) Pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc Natl Acad Sci USA 89:7370-7374
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7370-7374
    • Cortopassi, G.A.1    Shibata, D.2    Soong, N.W.3    Arnheim, N.A.4
  • 14
    • 0026532722 scopus 로고
    • Multiple mitochondrial DNA deletions in the elderly human individual
    • Zhang C, Baumer A, Maxwell RJ, Linnane AW, Nagley P (1992) Multiple mitochondrial DNA deletions in the elderly human individual. FEBS Lett 297:34-38
    • (1992) FEBS Lett , vol.297 , pp. 34-38
    • Zhang, C.1    Baumer, A.2    Maxwell, R.J.3    Linnane, A.W.4    Nagley, P.5
  • 15
    • 33646351299 scopus 로고    scopus 로고
    • Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
    • Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K (2006) Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet 38:518-520
    • (2006) Nat Genet , vol.38 , pp. 518-520
    • Kraytsberg, Y.1    Kudryavtseva, E.2    McKee, A.C.3    Geula, C.4    Kowall, N.W.5    Khrapko, K.6
  • 17
    • 0025674177 scopus 로고
    • Detection of specific mitochondrial DNA deletion in tissues of older humans
    • Cortopassi GA, Arnheim N (1990) Detection of specific mitochondrial DNA deletion in tissues of older humans. Nucleic Acids Res 18:6927-6933
    • (1990) Nucleic Acids Res , vol.18 , pp. 6927-6933
    • Cortopassi, G.A.1    Arnheim, N.2
  • 18
    • 0028787717 scopus 로고
    • Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle
    • Melov S, Shoffner JM, Kaufman A, Wallace DC (1995) Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle. Nucleic Acids Res 23:4122-4126
    • (1995) Nucleic Acids Res , vol.23 , pp. 4122-4126
    • Melov, S.1    Shoffner, J.M.2    Kaufman, A.3    Wallace, D.C.4
  • 19
    • 0026469073 scopus 로고
    • Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of aging
    • Cooper JM, Mann VM, Schapira AHV (1992) Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of aging. J Neurol Sci 113:91-98
    • (1992) J Neurol Sci , vol.113 , pp. 91-98
    • Cooper, J.M.1    Mann, V.M.2    Schapira, A.H.V.3
  • 20
    • 0021033860 scopus 로고
    • Focal deficiency of cytochrome-c-oxidase in skeletal muscle of patients with progressive external ophthalmoplegia: Cytochemical-fine-structural study
    • Müller-Höcker J, Pongratz D, Hubner G (1983) Focal deficiency of cytochrome-c-oxidase in skeletal muscle of patients with progressive external ophthalmoplegia: cytochemical-fine-structural study. Virchows Arch A Pathol Anat Histopathol 402:61-71
    • (1983) Virchows Arch A Pathol Anat Histopathol , vol.402 , pp. 61-71
    • Müller-Höcker, J.1    Pongratz, D.2    Hubner, G.3
  • 21
    • 0035504933 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: Analysis by laser-capture microdissection
    • Cao Z, Wanagat J, McKiernan SH, Aiken JM (2001) Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection. Nucleic Acids Res 29:4502-4508
    • (2001) Nucleic Acids Res , vol.29 , pp. 4502-4508
    • Cao, Z.1    Wanagat, J.2    McKiernan, S.H.3    Aiken, J.M.4
  • 23
    • 0025276996 scopus 로고
    • Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease
    • Shoubridge EA, Karpati G, Hastings KE (1990) Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease. Cell 62:43-49
    • (1990) Cell , vol.62 , pp. 43-49
    • Shoubridge, E.A.1    Karpati, G.2    Hastings, K.E.3
  • 24
    • 0026728212 scopus 로고
    • Progressive loss of cytochrome c oxidase in the human extraocular muscles in ageing - A cytochemical-immunohistochemical study
    • Müller-Höcker J, Schneiderbanger K, Stefani FH, Kadenbach B (1992) Progressive loss of cytochrome c oxidase in the human extraocular muscles in ageing-a cytochemical-immunohistochemical study. Mutat Res 275:115-124
    • (1992) Mutat Res , vol.275 , pp. 115-124
    • Müller-Höcker, J.1    Schneiderbanger, K.2    Stefani, F.H.3    Kadenbach, B.4
  • 25
    • 0027525966 scopus 로고
    • Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly
    • Müller-Höcker J, Seibel P, Schneiderbanger K, Kadenbach B (1993) Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly. Virchows Arch A Pathol Anat Histopathol 422:7-15
    • (1993) Virchows Arch A Pathol Anat Histopathol , vol.422 , pp. 7-15
    • Müller-Höcker, J.1    Seibel, P.2    Schneiderbanger, K.3    Kadenbach, B.4
  • 26
    • 0028936222 scopus 로고
    • Ragged red fibers in normal aging and inflammatory myopathy
    • Rifai Z, Welle S, Kamp C, Thornton C (1995) Ragged red fibers in normal aging and inflammatory myopathy. Ann Neurol 37:24-29
    • (1995) Ann Neurol , vol.37 , pp. 24-29
    • Rifai, Z.1    Welle, S.2    Kamp, C.3    Thornton, C.4
  • 27
    • 2442714255 scopus 로고    scopus 로고
    • Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle
    • Bua E, McKiernan SH, Aiken JM (2004) Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle. FASEB J 18:582-584
    • (2004) FASEB J , vol.18 , pp. 582-584
    • Bua, E.1    McKiernan, S.H.2    Aiken, J.M.3
  • 28
    • 0014311556 scopus 로고
    • Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB)
    • Seligman AM, Karnovsky MJ, Wasserkrug HL, Hanker JS (1968) Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB). J Cell Biol 38:1-14
    • (1968) J Cell Biol , vol.38 , pp. 1-14
    • Seligman, A.M.1    Karnovsky, M.J.2    Wasserkrug, H.L.3    Hanker, J.S.4
  • 30
    • 0032533691 scopus 로고    scopus 로고
    • Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy
    • Lee CM, Lopez ME, Weindruch R, Aiken JM (1998) Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radic Biol Med 25:964-972
    • (1998) Free Radic Biol Med , vol.25 , pp. 964-972
    • Lee, C.M.1    Lopez, M.E.2    Weindruch, R.3    Aiken, J.M.4
  • 31
    • 13844282117 scopus 로고    scopus 로고
    • Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys
    • Gokey NG, Cao Z, Pak JW, Lee D, McKiernan SH, McKenzie D, Weindruch R, Aiken JM (2004) Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys. Aging Cell 3:319-326
    • (2004) Aging Cell , vol.3 , pp. 319-326
    • Gokey, N.G.1    Cao, Z.2    Pak, J.W.3    Lee, D.4    McKiernan, S.H.5    McKenzie, D.6    Weindruch, R.7    Aiken, J.M.8
  • 34
    • 0036258718 scopus 로고    scopus 로고
    • Ageing muscle: Clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function
    • Fayet G, Jansson M, Sternberg D, Moslemi AR, Blondy P, Lombes A, Fardeau M, Oldfors A (2002) Ageing muscle: clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function. Neuromuscul Disord 12:484-493
    • (2002) Neuromuscul Disord , vol.12 , pp. 484-493
    • Fayet, G.1    Jansson, M.2    Sternberg, D.3    Moslemi, A.R.4    Blondy, P.5    Lombes, A.6    Fardeau, M.7    Oldfors, A.8
  • 35
    • 0033804530 scopus 로고    scopus 로고
    • Hypervariable sites in the mtDNA control region are mutational hotspots
    • Stoneking M (2000) Hypervariable sites in the mtDNA control region are mutational hotspots. Am J Hum Genet 67:1029-1032
    • (2000) Am J Hum Genet , vol.67 , pp. 1029-1032
    • Stoneking, M.1
  • 37
    • 0031885843 scopus 로고    scopus 로고
    • Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle
    • Brierley EJ, Johnson MA, Lightowlers RN, James OF, Turnbull DM (1998) Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle. Ann Neurol 43:217-223
    • (1998) Ann Neurol , vol.43 , pp. 217-223
    • Brierley, E.J.1    Johnson, M.A.2    Lightowlers, R.N.3    James, O.F.4    Turnbull, D.M.5
  • 38
    • 0028227936 scopus 로고
    • Mitochondrial encephalomyopathies: Clinical and molecular analysis
    • Schon EA, Hirano M, DiMauro S (1994) Mitochondrial encephalomyopathies: clinical and molecular analysis. J Bioenerg Biomembr 26:291-299
    • (1994) J Bioenerg Biomembr , vol.26 , pp. 291-299
    • Schon, E.A.1    Hirano, M.2    DiMauro, S.3
  • 40
    • 0028673946 scopus 로고
    • Multiple age-associated mitochondrial DNA deletions in skeletal muscle of mice
    • Chung SS, Weindruch R, Schwarze SR, McKenzie D, Aiken JM (1994) Multiple age-associated mitochondrial DNA deletions in skeletal muscle of mice. Aging 6:193-200
    • (1994) Aging , vol.6 , pp. 193-200
    • Chung, S.S.1    Weindruch, R.2    Schwarze, S.R.3    McKenzie, D.4    Aiken, J.M.5
  • 41
    • 0042388279 scopus 로고    scopus 로고
    • Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders
    • Copeland WC, Ponamarev MV, Nguyen D, Kunkel TA, Longley MJ (2003) Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders. Acta Biochim Pol 50:155-167
    • (2003) Acta Biochim Pol , vol.50 , pp. 155-167
    • Copeland, W.C.1    Ponamarev, M.V.2    Nguyen, D.3    Kunkel, T.A.4    Longley, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.