-
1
-
-
77049308856
-
Aging: Theory based on free radical and radiation chemistry
-
Harman D. Aging: Theory based on free radical and radiation chemistry. J Gerontol 11:298-300, 1956.
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
2
-
-
0015319592
-
The biological clock: The mitochondria?
-
Harman D. The biological clock: the mitochondria? J Am Geriatr Soc 20:145-147, 1972.
-
(1972)
J Am Geriatr Soc
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
3
-
-
0019644298
-
The aging process
-
Harman D. The aging process. Proc Natl Acad Sci USA 78:7124-7128, 1981.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 7124-7128
-
-
Harman, D.1
-
4
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 78:547-581, 1998.
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
6
-
-
0025864512
-
An integrated theory of aging as the result of mitochondrial DNA mutation in differentiated cells
-
Miquel J. An integrated theory of aging as the result of mitochondrial DNA mutation in differentiated cells. Arch Gerontol Geriatr 12:99-117, 1991.
-
(1991)
Arch Gerontol Geriatr
, vol.12
, pp. 99-117
-
-
Miquel, J.1
-
7
-
-
0024541837
-
Mitochondrial DNA mutations as an important contributor to ageing and degenerative disease
-
Linnane AW, Marzuki S, Ozawa T, Tanaka M. Mitochondrial DNA mutations as an important contributor to ageing and degenerative disease. Lancet i:642-645, 1989.
-
(1989)
Lancet
, vol.1
, pp. 642-645
-
-
Linnane, A.W.1
Marzuki, S.2
Ozawa, T.3
Tanaka, M.4
-
9
-
-
0032993576
-
Apoptosis in neurodegenerative diseases: The role of mitochondria
-
Tatton WG, Olanow CW. Apoptosis in neurodegenerative diseases: the role of mitochondria. Biochim Biophys Acta 1410:195-213, 1999.
-
(1999)
Biochim Biophys Acta
, vol.1410
, pp. 195-213
-
-
Tatton, W.G.1
Olanow, C.W.2
-
10
-
-
0024980878
-
Liver mitochondrial respiratory functions decline with age
-
Yen TC, Chen YS, King KL, Yeh SH, Wei YH. Liver mitochondrial respiratory functions decline with age. Biochem Biophys Res Commun 165:994-1003, 1989.
-
(1989)
Biochem Biophys Res Commun
, vol.165
, pp. 994-1003
-
-
Yen, T.C.1
Chen, Y.S.2
King, K.L.3
Yeh, S.H.4
Wei, Y.H.5
-
11
-
-
0026469073
-
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
-
Cooper JM, Mann VM, Schapira AH. Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing. J Neurol Sci 113:91-98, 1992.
-
(1992)
J Neurol Sci
, vol.113
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.3
-
12
-
-
2542505678
-
Oxidative stress and mitochondrial DNA mutations in human aging
-
Wei YH. Oxidative stress and mitochondrial DNA mutations in human aging. Proc Soc Exp Biol Med 217:53-63, 1998.
-
(1998)
Proc Soc Exp Biol Med
, vol.217
, pp. 53-63
-
-
Wei, Y.H.1
-
13
-
-
0032547237
-
Increase in intracellular hydrogen peroxide and upregulation of nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells
-
Suzuki H, Kumagai T, Goto A, Sugiura T. Increase in intracellular hydrogen peroxide and upregulation of nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells. Biochem Biophys Res Commun 249:542-545, 1998.
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 542-545
-
-
Suzuki, H.1
Kumagai, T.2
Goto, A.3
Sugiura, T.4
-
14
-
-
0033609069
-
Mitochondrial disease in mouse results in increased oxidative stress
-
Esposito LA, Melov S, Panov A, Cottrell BA, Wallace DC. Mitochondrial disease in mouse results in increased oxidative stress. Proc Natl Acad Sci USA 96:4820-4825, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4820-4825
-
-
Esposito, L.A.1
Melov, S.2
Panov, A.3
Cottrell, B.A.4
Wallace, D.C.5
-
15
-
-
0033525773
-
Mitochondrial disease in man and mouse
-
Wallace DC. Mitochondrial disease in man and mouse. Science 283:1482-1488, 1999.
-
(1999)
Science
, vol.283
, pp. 1482-1488
-
-
Wallace, D.C.1
-
16
-
-
0030859876
-
Mutation and oxidative damage of mitochondrial DNA and defective turnover of mitochondria in human aging
-
Lee HC, Wei YH. Mutation and oxidative damage of mitochondrial DNA and defective turnover of mitochondria in human aging. J Formos Med Assoc 96:770-778, 1997.
-
(1997)
J Formos Med Assoc
, vol.96
, pp. 770-778
-
-
Lee, H.C.1
Wei, Y.H.2
-
17
-
-
0028574053
-
Mitochondrial DNA sequence variation in human evolution and disease
-
Wallace DC. Mitochondrial DNA sequence variation in human evolution and disease. Proc Natl Acad Sci USA 91:8739-8746, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8739-8746
-
-
Wallace, D.C.1
-
18
-
-
0016327931
-
The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells
-
Bogenhagen D, Clayton DA. The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells. J Biol Chem 249:7991-7995, 1974.
-
(1974)
J Biol Chem
, vol.249
, pp. 7991-7995
-
-
Bogenhagen, D.1
Clayton, D.A.2
-
19
-
-
0026746336
-
Mitochondrial DNA alterations as ageing-associated molecular events
-
Wei YH. Mitochondrial DNA alterations as ageing-associated molecular events. Mutat Res 275:145-155, 1992.
-
(1992)
Mutat Res
, vol.275
, pp. 145-155
-
-
Wei, Y.H.1
-
20
-
-
0028574053
-
Mitochondrial DNA sequence variation in human evolution and disease
-
Wallace DC. Mitochondrial DNA sequence variation in human evolution and disease. Proc Natl Acad Sci USA 91:8739-8746, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8739-8746
-
-
Wallace, D.C.1
-
21
-
-
0025674177
-
Detection of a specific mitochondrial DNA deletion in tissues of older humans
-
Cortopassi GA, Arnheim N. Detection of a specific mitochondrial DNA deletion in tissues of older humans. Nucleic Acids Res 18:6927-6933, 1990.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 6927-6933
-
-
Cortopassi, G.A.1
Arnheim, N.2
-
22
-
-
0025758425
-
Age-dependent increase in deleted mitochondrial DNA in the human heart: Possible contributory factor to presbycardia
-
Hattori K, Tanaka M, Sugiyama S, Obayashi T, Ito T, Satake T, Hanaki Y, Asai J, Nagano M, Ozawa T. Age-dependent increase in deleted mitochondrial DNA in the human heart: possible contributory factor to presbycardia. Am Heart J 121:1735-1742, 1991.
-
(1991)
Am Heart J
, vol.121
, pp. 1735-1742
-
-
Hattori, K.1
Tanaka, M.2
Sugiyama, S.3
Obayashi, T.4
Ito, T.5
Satake, T.6
Hanaki, Y.7
Asai, J.8
Nagano, M.9
Ozawa, T.10
-
23
-
-
0026340875
-
Deleted mitochondrial DNA in the skeletal muscle of aged individuals
-
Katayama M, Tanaka M, Yamamoto H, Ohbayashi T, Nimura Y, Ozawa T. Deleted mitochondrial DNA in the skeletal muscle of aged individuals. Biochem Int 25:47-56, 1991.
-
(1991)
Biochem Int
, vol.25
, pp. 47-56
-
-
Katayama, M.1
Tanaka, M.2
Yamamoto, H.3
Ohbayashi, T.4
Nimura, Y.5
Ozawa, T.6
-
24
-
-
0025741445
-
Ageing-associated 5 kb deletion in human liver mitochondrial DNA
-
Yen TC, Su JH, King KL, Wei YH. Ageing-associated 5 kb deletion in human liver mitochondrial DNA. Biochem Biophys Res Commun 178:124-131, 1991.
-
(1991)
Biochem Biophys Res Commun
, vol.178
, pp. 124-131
-
-
Yen, T.C.1
Su, J.H.2
King, K.L.3
Wei, Y.H.4
-
25
-
-
0026860988
-
Ageing-associated deletions of human diaphragmatic mitochondrial DNA
-
Torii K, Sugiyama S, Tanaka M, Takagi K, Hanaki Y, Iida K, Matsuyama M, Hirabayashi N, Uno H, Ozawa T. Ageing-associated deletions of human diaphragmatic mitochondrial DNA. Am J Respir Cell Mol Biol 6:543-549, 1992.
-
(1992)
Am J Respir Cell Mol Biol
, vol.6
, pp. 543-549
-
-
Torii, K.1
Sugiyama, S.2
Tanaka, M.3
Takagi, K.4
Hanaki, Y.5
Iida, K.6
Matsuyama, M.7
Hirabayashi, N.8
Uno, H.9
Ozawa, T.10
-
26
-
-
0026532722
-
Multiple mitochondrial DNA deletions in an elderly human individual
-
Zhang C, Baumer A, Maxwell RJ, Linnane AW, Nagley P. Multiple mitochondrial DNA deletions in an elderly human individual. FEBS Lett 297:34-38, 1992.
-
(1992)
FEBS Lett
, vol.297
, pp. 34-38
-
-
Zhang, C.1
Baumer, A.2
Maxwell, R.J.3
Linnane, A.W.4
Nagley, P.5
-
27
-
-
0026553006
-
Age-dependent 6 kb deletion in human liver mitochondrial DNA
-
Yen TC, Pang CY, Hsieh JH, Su CH, King KL, Wei YH. Age-dependent 6 kb deletion in human liver mitochondrial DNA. Biochem Int 26:457-468, 1992.
-
(1992)
Biochem Int
, vol.26
, pp. 457-468
-
-
Yen, T.C.1
Pang, C.Y.2
Hsieh, J.H.3
Su, C.H.4
King, K.L.5
Wei, Y.H.6
-
28
-
-
0028349234
-
Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing
-
Lee HC, Pang CY, Hsu HS, Wei YH. Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing. Biochim Biophys Acta 1226:37-43, 1994.
-
(1994)
Biochim Biophys Acta
, vol.1226
, pp. 37-43
-
-
Lee, H.C.1
Pang, C.Y.2
Hsu, H.S.3
Wei, Y.H.4
-
29
-
-
0028061412
-
Ageing-associated tandem duplications in the D-loop of mitochondrial DNA of human muscle
-
Lee HC, Pang CY, Hsu HS, Wei YH. Ageing-associated tandem duplications in the D-loop of mitochondrial DNA of human muscle. FEBS Lett 354:79-83, 1994.
-
(1994)
FEBS Lett
, vol.354
, pp. 79-83
-
-
Lee, H.C.1
Pang, C.Y.2
Hsu, H.S.3
Wei, Y.H.4
-
30
-
-
0027963448
-
A specific 4,977 bp deletion of mitochondrial DNA in human ageing skin
-
Yang JH, Lee HC, Lin KJ, Wei YH. A specific 4,977 bp deletion of mitochondrial DNA in human ageing skin. Arch Dermatol Res 286:386-390, 1994.
-
(1994)
Arch Dermatol Res
, vol.286
, pp. 386-390
-
-
Yang, J.H.1
Lee, H.C.2
Lin, K.J.3
Wei, Y.H.4
-
31
-
-
0029121602
-
Photoageing-associated mitochondrial DNA length mutations in human skin
-
Yang JH, Lee HC, Wei YH. Photoageing-associated mitochondrial DNA length mutations in human skin. Arch Dermatol Res 287:641-648, 1995.
-
(1995)
Arch Dermatol Res
, vol.287
, pp. 641-648
-
-
Yang, J.H.1
Lee, H.C.2
Wei, Y.H.3
-
32
-
-
0029919382
-
Age-related 4,977 bp deletion in human lung mitochondrial DNA
-
Fahn HJ, Wang LS, Hsieh RH, Chang SC, Kao SH, Huang MH, Wei YH. Age-related 4,977 bp deletion in human lung mitochondrial DNA. Am J Respir Crit Care Med 154:1141-1145, 1996.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 1141-1145
-
-
Fahn, H.J.1
Wang, L.S.2
Hsieh, R.H.3
Chang, S.C.4
Kao, S.H.5
Huang, M.H.6
Wei, Y.H.7
-
33
-
-
0023883150
-
Deletions of mitochondrial DNA in patients with mitochondrial myopathies
-
Holt IJ, Harding AE, Morgan-Hughes JA. Deletions of mitochondrial DNA in patients with mitochondrial myopathies. Nature 331:717-719, 1988.
-
(1988)
Nature
, vol.331
, pp. 717-719
-
-
Holt, I.J.1
Harding, A.E.2
Morgan-Hughes, J.A.3
-
34
-
-
0024317560
-
Spontaneous Kearns-Sayre/chronic progressive external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: A slip-replication model and metabolic therapy
-
Shoffner JM, Lott MT, Voljavec AS, Soueidan SA, Costigan DA, Wallace DC. Spontaneous Kearns-Sayre/chronic progressive external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: A slip-replication model and metabolic therapy. Proc Natl Acad Sci USA 86:7952-7956, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7952-7956
-
-
Shoffner, J.M.1
Lott, M.T.2
Voljavec, A.S.3
Soueidan, S.A.4
Costigan, D.A.5
Wallace, D.C.6
-
35
-
-
0023813744
-
Deletions of mitochondrial DNA in Keams-Sayre syndrome
-
Zeviani M, Moraes CT, DiMauro S, Nakase H, Bonilla E, Schon EA, Rowland LP. Deletions of mitochondrial DNA in Keams-Sayre syndrome. Neurology 38:1339-1346, 1988.
-
(1988)
Neurology
, vol.38
, pp. 1339-1346
-
-
Zeviani, M.1
Moraes, C.T.2
DiMauro, S.3
Nakase, H.4
Bonilla, E.5
Schon, E.A.6
Rowland, L.P.7
-
36
-
-
0026624980
-
Diseases of the mitochondrial DNA
-
Wallace DC. Diseases of the mitochondrial DNA. Annu Rev Biochem 61:1175-1212, 1992.
-
(1992)
Annu Rev Biochem
, vol.61
, pp. 1175-1212
-
-
Wallace, D.C.1
-
37
-
-
0027476395
-
The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages
-
Münscher C, Rieger T, Müller-Höcker J, Kadenbach B. The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages. FEBS Lett 317:27-30, 1993.
-
(1993)
FEBS Lett
, vol.317
, pp. 27-30
-
-
Münscher, C.1
Rieger, T.2
Müller-Höcker, J.3
Kadenbach, B.4
-
38
-
-
0027198359
-
Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans
-
Zhang C, Linnane AW, Nagley P. Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans. Biochem Biophys Res Commun 195:1104-1110, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.195
, pp. 1104-1110
-
-
Zhang, C.1
Linnane, A.W.2
Nagley, P.3
-
39
-
-
0031594165
-
Independent occurrence of somatic mutations in mitochondrial DNA of human skin from subjects of various ages
-
Liu VWS, Zhang C, Pang CY, Lee HC, Lu CY, Wei YH, Nagley P. Independent occurrence of somatic mutations in mitochondrial DNA of human skin from subjects of various ages. Hum Mutat 11:191-196, 1998.
-
(1998)
Hum Mutat
, vol.11
, pp. 191-196
-
-
Liu, V.W.S.1
Zhang, C.2
Pang, C.Y.3
Lee, H.C.4
Lu, C.Y.5
Wei, Y.H.6
Nagley, P.7
-
40
-
-
0033595684
-
Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
-
Michikawa Y, Mazzucchelli F, Bresolin N, Scarlato G, Attardi G. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication. Science 286:774-779, 1999.
-
(1999)
Science
, vol.286
, pp. 774-779
-
-
Michikawa, Y.1
Mazzucchelli, F.2
Bresolin, N.3
Scarlato, G.4
Attardi, G.5
-
41
-
-
0029864498
-
Human brain contains high levels of heteroplasmy in the noncoding regions of mitochondrial DNA
-
Jazin EE, Cavelier L, Eriksson I, Oreland L, Gyllensten U. Human brain contains high levels of heteroplasmy in the noncoding regions of mitochondrial DNA. Proc Natl Acad Sci USA 93:12382-12387, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12382-12387
-
-
Jazin, E.E.1
Cavelier, L.2
Eriksson, I.3
Oreland, L.4
Gyllensten, U.5
-
42
-
-
0030582373
-
Age-related extensive fragmentation of mitochondrial DNA into minicircles
-
Hayakawa M, Katsumata K, Yoneda M, Tanaka M, Sugiyama S, Ozawa T. Age-related extensive fragmentation of mitochondrial DNA into minicircles. Biochem Biophys Res Commun 226:369-377, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.226
, pp. 369-377
-
-
Hayakawa, M.1
Katsumata, K.2
Yoneda, M.3
Tanaka, M.4
Sugiyama, S.5
Ozawa, T.6
-
43
-
-
0032401024
-
Ageing and mammalian mitochondrial genetics
-
Nagley P, Wei YH. Ageing and mammalian mitochondrial genetics. Trends Genet 14:513-517, 1998.
-
(1998)
Trends Genet
, vol.14
, pp. 513-517
-
-
Nagley, P.1
Wei, Y.H.2
-
44
-
-
0029029472
-
The universality of bioenergetic disease and amelioration with redox therapy
-
Linnane AW, Esposti MD, Generowicz M, Luff AR, Nagley P. The universality of bioenergetic disease and amelioration with redox therapy. Biochim Biophys Acta 1271:191-194, 1995.
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 191-194
-
-
Linnane, A.W.1
Esposti, M.D.2
Generowicz, M.3
Luff, A.R.4
Nagley, P.5
-
45
-
-
0031555864
-
Deltoid human muscle mtDNA is extensively rearranged in old age subjects
-
Kovalenko SA, Kopsidas G, Kelso JM, Linnane AW. Deltoid human muscle mtDNA is extensively rearranged in old age subjects. Biochem Biophys Res Commun 232:147-152, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.232
, pp. 147-152
-
-
Kovalenko, S.A.1
Kopsidas, G.2
Kelso, J.M.3
Linnane, A.W.4
-
46
-
-
0032511842
-
An age-associated correlation between cellular bioenergy decline and mtDNA rearrangements in human skeletal muscle
-
Kopsidas G, Kovalenko SA, Kelso JM, Linnane AW. An age-associated correlation between cellular bioenergy decline and mtDNA rearrangements in human skeletal muscle. Mutat Res 421:27-36, 1998.
-
(1998)
Mutat Res
, vol.421
, pp. 27-36
-
-
Kopsidas, G.1
Kovalenko, S.A.2
Kelso, J.M.3
Linnane, A.W.4
-
47
-
-
0029894544
-
Crosstalk between nuclear and mitochondrial genomes
-
Poyton RO, McEwen JE. Crosstalk between nuclear and mitochondrial genomes. Annu Rev Biochem 65:563-607, 1996.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 563-607
-
-
Poyton, R.O.1
McEwen, J.E.2
-
48
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Anderson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98:115-124, 1999.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Anderson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
-
49
-
-
0030835513
-
Nuclear control of respiratory chain expression in mammalian cells
-
Scarpulla RC. Nuclear control of respiratory chain expression in mammalian cells. J Bioenerg Biomembr 29:109-119, 1997.
-
(1997)
J Bioenerg Biomembr
, vol.29
, pp. 109-119
-
-
Scarpulla, R.C.1
-
50
-
-
0024366601
-
Cytochrome c oxidase deficient cardiomyocytes in the human heart-an age-related phenomenon: A histochemical ultracytochemical study
-
Müller-Höcker J. Cytochrome c oxidase deficient cardiomyocytes in the human heart-an age-related phenomenon: a histochemical ultracytochemical study. Am J Pathol 134:1167-1173, 1989.
-
(1989)
Am J Pathol
, vol.134
, pp. 1167-1173
-
-
Müller-Höcker, J.1
-
51
-
-
0025673968
-
Cytochrome c oxidase-deficient fibers in the limb muscle and diaphragm of man without muscular disease: An age-related alteration
-
Müller-Höcker J. Cytochrome c oxidase-deficient fibers in the limb muscle and diaphragm of man without muscular disease: an age-related alteration. J Neurol Sci 100:14-21, 1990.
-
(1990)
J Neurol Sci
, vol.100
, pp. 14-21
-
-
Müller-Höcker, J.1
-
52
-
-
0027525966
-
Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibers in the elderly
-
Müller-Höcker J, Seibel P, Schneiderbanger K, Kadenbach B. Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibers in the elderly. Virch Arch 422:7-15, 1993.
-
(1993)
Virch Arch
, vol.422
, pp. 7-15
-
-
Müller-Höcker, J.1
Seibel, P.2
Schneiderbanger, K.3
Kadenbach, B.4
-
53
-
-
0024580556
-
Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor in ageing
-
Trounce I, Byrne E, Marzuki S. Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing. Lancet i:637-639, 1989.
-
(1989)
Lancet
, vol.1
, pp. 637-639
-
-
Trounce, I.1
Byrne, E.2
Marzuki, S.3
-
54
-
-
0028235259
-
Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria
-
Hsieh RH, Hou JH, Hsu HS, Wei YH. Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria. Biochem Mol Biol Int 32:1009-1022, 1994.
-
(1994)
Biochem Mol Biol Int
, vol.32
, pp. 1009-1022
-
-
Hsieh, R.H.1
Hou, J.H.2
Hsu, H.S.3
Wei, Y.H.4
-
55
-
-
0030581498
-
Mitochondrial oxidative phosphorylation changes in the life span: Molecular aspects and physiopathological implications
-
Papa S. Mitochondrial oxidative phosphorylation changes in the life span: molecular aspects and physiopathological implications. Biochim Biophys Acta 1276:87-105, 1996.
-
(1996)
Biochim Biophys Acta
, vol.1276
, pp. 87-105
-
-
Papa, S.1
-
56
-
-
0027244097
-
Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced
-
Calleja M, Pena P, Ugalde C, Ferreiro C, Marco R, Garesse R. Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced. J Biol Chem 268:18891-18897, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 18891-18897
-
-
Calleja, M.1
Pena, P.2
Ugalde, C.3
Ferreiro, C.4
Marco, R.5
Garesse, R.6
-
57
-
-
0025115244
-
Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of L-carnitine
-
Gadaleta MN, Petruzzella V, Renis M, Fracasso F, Cantatore P. Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of L-carnitine. Eur J Biochem 187:501-506, 1990.
-
(1990)
Eur J Biochem
, vol.187
, pp. 501-506
-
-
Gadaleta, M.N.1
Petruzzella, V.2
Renis, M.3
Fracasso, F.4
Cantatore, P.5
-
58
-
-
0025777672
-
Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain
-
Fernandez-Silva SP, Petruzzela V, Fracasso F, Gadaleta MN, Cantatore P. Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain. Biochem Biophys Res Commun 176:645-653, 1991.
-
(1991)
Biochem Biophys Res Commun
, vol.176
, pp. 645-653
-
-
Fernandez-Silva, S.P.1
Petruzzela, V.2
Fracasso, F.3
Gadaleta, M.N.4
Cantatore, P.5
-
59
-
-
0031430744
-
Qualitative and quantitative changes in skeletal muscle mtDNA and expression of mitochondrial-encoded genes in the human aging process
-
Barrientos A, Casademont J, Cardellach F, Ardite E, Estivill X, Urbano-Marquez A, Fernandez-Checa JC, Nunes V. Qualitative and quantitative changes in skeletal muscle mtDNA and expression of mitochondrial-encoded genes in the human aging process. Biochem Mol Med 62:165-171, 1997.
-
(1997)
Biochem Mol Med
, vol.62
, pp. 165-171
-
-
Barrientos, A.1
Casademont, J.2
Cardellach, F.3
Ardite, E.4
Estivill, X.5
Urbano-Marquez, A.6
Fernandez-Checa, J.C.7
Nunes, V.8
-
60
-
-
0031574362
-
Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging
-
Barrientos A, Casademont J, Cardellach F, Estivill X, Urbano-Marquez A, Nunes V. Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging. Mol Brain Res 52:284-289, 1997.
-
(1997)
Mol Brain Res
, vol.52
, pp. 284-289
-
-
Barrientos, A.1
Casademont, J.2
Cardellach, F.3
Estivill, X.4
Urbano-Marquez, A.5
Nunes, V.6
-
61
-
-
0033048003
-
Oxidative insult specifically decreases levels of a mitochondrial transcript
-
Elliott RM, Southon S, Archer DB. Oxidative insult specifically decreases levels of a mitochondrial transcript. Free Radic Biol Med 26:646-655, 1999.
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 646-655
-
-
Elliott, R.M.1
Southon, S.2
Archer, D.B.3
-
62
-
-
0029621249
-
Changes in the respiratory chain complexes activities and in the mitochondrial DNA content during ageing in D. subobscura
-
Morel F, Mazet F, Touraille S, Alziari S. Changes in the respiratory chain complexes activities and in the mitochondrial DNA content during ageing in D. subobscura. Mech Ageing Dev 84:171-181, 1995.
-
(1995)
Mech Ageing Dev
, vol.84
, pp. 171-181
-
-
Morel, F.1
Mazet, F.2
Touraille, S.3
Alziari, S.4
-
63
-
-
0026712284
-
Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats
-
Gadaleta MN, Rainaldi G, Lezza AMS, Milella F, Fracasso F, Cantatore P. Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats. Mutat Res 275:181-193, 1992.
-
(1992)
Mutat Res
, vol.275
, pp. 181-193
-
-
Gadaleta, M.N.1
Rainaldi, G.2
Lezza, A.M.S.3
Milella, F.4
Fracasso, F.5
Cantatore, P.6
-
64
-
-
0032429396
-
Aging- and smoking-associated alteration in the relative content of mitochondrial DNA in human lung
-
Lee HC, Lu CY, Fahn HJ, Wei YH. Aging- and smoking-associated alteration in the relative content of mitochondrial DNA in human lung. FEBS Lett 441:292-296, 1998.
-
(1998)
FEBS Lett
, vol.441
, pp. 292-296
-
-
Lee, H.C.1
Lu, C.Y.2
Fahn, H.J.3
Wei, Y.H.4
-
65
-
-
0035371185
-
Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle
-
Pesce V, Cormio A, Fracasso F, Vecchiet J, Felzani G, Lezza AMS, Cantatore P, Gadaleta MN. Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle. Free Radic Biol Med 30:1223-1233, 2001.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 1223-1233
-
-
Pesce, V.1
Cormio, A.2
Fracasso, F.3
Vecchiet, J.4
Felzani, G.5
Lezza, A.M.S.6
Cantatore, P.7
Gadaleta, M.N.8
-
66
-
-
0025948247
-
Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm
-
Hayakawa M, Torii K, Sugiyama S, Tanaka M, Ozawa T. Age- associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm. Biochem Biophys Res Commun 179:1023-1029, 1991.
-
(1991)
Biochem Biophys Res Commun
, vol.179
, pp. 1023-1029
-
-
Hayakawa, M.1
Torii, K.2
Sugiyama, S.3
Tanaka, M.4
Ozawa, T.5
-
67
-
-
0029762274
-
Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging
-
Wei YH, Kao SH, Lee HC. Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging. Ann NY Acad Sci 786:24-43, 1996.
-
(1996)
Ann NY Acad Sci
, vol.786
, pp. 24-43
-
-
Wei, Y.H.1
Kao, S.H.2
Lee, H.C.3
-
68
-
-
0033557111
-
Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging: Smoking enhances oxidative stress on the aged tissues
-
Lee HC, Lim MLR, Lu CY, Liu VWS, Fahn HJ, Zhang C, Nagley P, Wei YH. Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging: Smoking enhances oxidative stress on the aged tissues. Arch Biochem Biophys 362:309-316, 1999.
-
(1999)
Arch Biochem Biophys
, vol.362
, pp. 309-316
-
-
Lee, H.C.1
Lim, M.L.R.2
Lu, C.Y.3
Liu, V.W.S.4
Fahn, H.J.5
Zhang, C.6
Nagley, P.7
Wei, Y.H.8
-
69
-
-
0027186186
-
Age-dependent modifications of mitochondrial trans-membrane potential and mass in rat splenic lymphocytes during proliferation
-
Pieri C, Recchioni R, Moroni F. Age-dependent modifications of mitochondrial trans-membrane potential and mass in rat splenic lymphocytes during proliferation. Mech Ageing Dev 70:201-212, 1993.
-
(1993)
Mech Ageing Dev
, vol.70
, pp. 201-212
-
-
Pieri, C.1
Recchioni, R.2
Moroni, F.3
-
70
-
-
0030915483
-
Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase
-
Hagen TM, Yowe DL, Bartholomew JC, Wehr CM, Do KL, Park JY, Ames BN. Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci USA 94:3064-3069, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3064-3069
-
-
Hagen, T.M.1
Yowe, D.L.2
Bartholomew, J.C.3
Wehr, C.M.4
Do, K.L.5
Park, J.Y.6
Ames, B.N.7
-
71
-
-
0032992534
-
Mitochondria in organismal aging and degeneration
-
Cortopassi GA, Wong A. Mitochondria in organismal aging and degeneration. Biochim Biophys Acta 1410:183-193, 1999.
-
(1999)
Biochim Biophys Acta
, vol.1410
, pp. 183-193
-
-
Cortopassi, G.A.1
Wong, A.2
-
72
-
-
0031869858
-
Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes
-
Harper ME, Monemdjou S, Ramsey JJ, Weindruch R. Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes. Am J Physiol 275:E 197-E206, 1998.
-
(1998)
Am J Physiol
, vol.275
-
-
Harper, M.E.1
Monemdjou, S.2
Ramsey, J.J.3
Weindruch, R.4
-
73
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide: General properties and effect of hyperbaric oxygen
-
Boveris A, Chance B. The mitochondrial generation of hydrogen peroxide: general properties and effect of hyperbaric oxygen. Biochem J 134:707-716, 1973.
-
(1973)
Biochem J
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
74
-
-
0019891031
-
1 complex of mitochondrial electron transport chain: Emonstration of QP-S radical formation
-
1 complex of mitochondrial electron transport chain: emonstration of QP-S radical formation. Biochem Biophys Res Commun 99:1411-1419, 1981.
-
(1981)
Biochem Biophys Res Commun
, vol.99
, pp. 1411-1419
-
-
Wei, Y.H.1
Scholes, C.P.2
King, T.E.3
-
75
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev 59:527-605, 1979.
-
(1979)
Physiol Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
76
-
-
0026023219
-
Hydrogen peroxide release by mitochondria increases during aging
-
Sohal RS, Sohal BH. Hydrogen peroxide release by mitochondria increases during aging. Mech Ageing Dev 57:187-202, 1991.
-
(1991)
Mech Ageing Dev
, vol.57
, pp. 187-202
-
-
Sohal, R.S.1
Sohal, B.H.2
-
77
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation, and antioxidant defenses during aging and in response to food restriction in the mouse
-
Sohal RS, Ku HH, Agarwal S, Forster MJ, Lal H. Oxidative damage, mitochondrial oxidant generation, and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev 74:121-133, 1994.
-
(1994)
Mech Ageing Dev
, vol.74
, pp. 121-133
-
-
Sohal, R.S.1
Ku, H.H.2
Agarwal, S.3
Forster, M.J.4
Lal, H.5
-
78
-
-
1542563727
-
The rate of free radical production as a determinant of the rate of aging: Evidence from the comparative approach
-
Perez-Campo R, Lopez-Torres M, Cadenas S, Rojas C, Barja G. The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach. J Comp Physiol 168:149-158, 1998.
-
(1998)
J Comp Physiol
, vol.168
, pp. 149-158
-
-
Perez-Campo, R.1
Lopez-Torres, M.2
Cadenas, S.3
Rojas, C.4
Barja, G.5
-
79
-
-
0028268734
-
Mitochondrial oxidative damage, hydrogen peroxide release, and aging
-
Sohal RS, Dubey A. Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Radic Biol Med 16:621-626, 1994.
-
(1994)
Free Radic Biol Med
, vol.16
, pp. 621-626
-
-
Sohal, R.S.1
Dubey, A.2
-
80
-
-
0029147191
-
Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies
-
Sohal RS, Sohal BH, Orr WC. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. Free Radic Biol Med 19:499-504, 1995.
-
(1995)
Free Radic Biol Med
, vol.19
, pp. 499-504
-
-
Sohal, R.S.1
Sohal, B.H.2
Orr, W.C.3
-
81
-
-
0029039854
-
Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster
-
Sohal RS, Agarwal A, Agarwal S, Orr WC. Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster. J Biol Chem 270:15671-15674, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 15671-15674
-
-
Sohal, R.S.1
Agarwal, A.2
Agarwal, S.3
Orr, W.C.4
-
82
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
Richter C, Park JW, Ames BN. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci USA 85:6465-6467, 1988.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
83
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman ER. Protein oxidation and aging. Science 257:1220-1224, 1992.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
84
-
-
0027328852
-
Protein oxidative damage is associated with life expectancy of houseflies
-
Sohal RS, Agarwal S, Dubey A, Orr WC. Protein oxidative damage is associated with life expectancy of houseflies. Proc Natl Acad Sci USA 90:7255-7259, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7255-7259
-
-
Sohal, R.S.1
Agarwal, S.2
Dubey, A.3
Orr, W.C.4
-
85
-
-
0027055332
-
Age-associated oxygen damage and mutations in mitochondrial DNA in human heart
-
Hayakawa M, Hattori K, Sugiyama S, Ozawa T. Age-associated oxygen damage and mutations in mitochondrial DNA in human heart. Biochem Biophys Res Commun 189:979-985, 1992.
-
(1992)
Biochem Biophys Res Commun
, vol.189
, pp. 979-985
-
-
Hayakawa, M.1
Hattori, K.2
Sugiyama, S.3
Ozawa, T.4
-
86
-
-
0000350066
-
Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA
-
Garcia de la Asuncion J, Millán A, Pla R, Bruseghini L, Esteras A, Pallardó FV, Sastre J, Vifia J. Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA. FASEB J 10:333-338, 1996.
-
(1996)
FASEB J
, vol.10
, pp. 333-338
-
-
Garcia de la Asuncion, J.1
Millán, A.2
Pla, R.3
Bruseghini, L.4
Esteras, A.5
Pallardó, F.V.6
Sastre, J.7
Vifia, J.8
-
87
-
-
1842338036
-
Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with Complex I deficiency
-
Luo X, Pitkanen S, Kassovska-Bratinova S, Robinson BH, Lehotay D. Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with Complex I deficiency. J Clin Invest 99:2877-2882, 1997.
-
(1997)
J Clin Invest
, vol.99
, pp. 2877-2882
-
-
Luo, X.1
Pitkanen, S.2
Kassovska-Bratinova, S.3
Robinson, B.H.4
Lehotay, D.5
-
88
-
-
0030059079
-
Aging-dependent functional alterations of mitochondrial DNA (mtDNA) from fibroblasts transformed into mtDNA-less cells
-
Laderman KA, Penny JR, Mazzucchelli F, Bresolin N, Scarlato G, Attardi G. Aging-dependent functional alterations of mitochondrial DNA (mtDNA) from fibroblasts transformed into mtDNA-less cells. J Biol Chem 271:15891-15897, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 15891-15897
-
-
Laderman, K.A.1
Penny, J.R.2
Mazzucchelli, F.3
Bresolin, N.4
Scarlato, G.5
Attardi, G.6
-
89
-
-
0020964045
-
Mitochondrial DNA in mortal and immortal human cells
-
Shmookler Reis RJ, Goldstein S. Mitochondrial DNA in mortal and immortal human cells. J Biol Chem 258:9078-9085, 1983.
-
(1983)
J Biol Chem
, vol.258
, pp. 9078-9085
-
-
Shmookler Reis, R.J.1
Goldstein, S.2
-
90
-
-
0036420161
-
Increase of mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence
-
In press
-
Lee HC, Yin PH, Chi CW, Wei YH. Increase of mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J Biomed Sci. In press.
-
J Biomed Sci
-
-
Lee, H.C.1
Yin, P.H.2
Chi, C.W.3
Wei, Y.H.4
-
91
-
-
0034214103
-
Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells
-
Lee HC, Yin PH, Lu CY, Chi CW, Wei YH. Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells. Biochem J 348:425-432, 2000.
-
(2000)
Biochem J
, vol.348
, pp. 425-432
-
-
Lee, H.C.1
Yin, P.H.2
Lu, C.Y.3
Chi, C.W.4
Wei, Y.H.5
-
92
-
-
0035685590
-
Mitochondrial alterations, cellular response to oxidative stress and defective degradation of proteins in aging
-
Lee HC, Wei YH. Mitochondrial alterations, cellular response to oxidative stress and defective degradation of proteins in aging. Biogerontology 2:231-244, 2001.
-
(2001)
Biogerontology
, vol.2
, pp. 231-244
-
-
Lee, H.C.1
Wei, Y.H.2
-
93
-
-
0031032817
-
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
-
Yakes FM, van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 94:514-519, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 514-519
-
-
Yakes, F.M.1
Van Houten, B.2
-
94
-
-
0028788763
-
Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-κB: Studies with isolated mitochondria and rat hepatocytes
-
Garcia-Ruiz C, Colell A, Morales A, Kaplowitz N, Fernandez-Checa JC. Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-κB: studies with isolated mitochondria and rat hepatocytes. Mol Pharmacol 48:825-834, 1995.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 825-834
-
-
Garcia-Ruiz, C.1
Colell, A.2
Morales, A.3
Kaplowitz, N.4
Fernandez-Checa, J.C.5
-
95
-
-
13044285432
-
Mitochondrial disease in superoxide dismutase 2 mutant mice
-
Melov S, Coskun P, Patel M, Tuinstra R, Cottrell B, Jun AS, Zastawny TH, Dizdaroglu M, Goodman SI, Huang TT, Miziorko H, Epstein CJ, Wallace DC. Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc Natl Acad Sci USA 96:846-851, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 846-851
-
-
Melov, S.1
Coskun, P.2
Patel, M.3
Tuinstra, R.4
Cottrell, B.5
Jun, A.S.6
Zastawny, T.H.7
Dizdaroglu, M.8
Goodman, S.I.9
Huang, T.T.10
Miziorko, H.11
Epstein, C.J.12
Wallace, D.C.13
-
96
-
-
0031593219
-
Lipid peroxidation, antioxidant protection and aging
-
Rikans LE, Hornbrook KR. Lipid peroxidation, antioxidant protection and aging. Biochim Biophys Acta 1362:116-127, 1997.
-
(1997)
Biochim Biophys Acta
, vol.1362
, pp. 116-127
-
-
Rikans, L.E.1
Hornbrook, K.R.2
-
97
-
-
0033520497
-
Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major matrix-degrading metalloprotease-1
-
Wenk J, Brenneisen P, Walschek M, Poswig A, Brivibas K, Oberley TD, Scharffetter-Kochanek K. Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major matrix-degrading metalloprotease-1. J Biol Chem 274:25869-25876, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 25869-25876
-
-
Wenk, J.1
Brenneisen, P.2
Walschek, M.3
Poswig, A.4
Brivibas, K.5
Oberley, T.D.6
Scharffetter-Kochanek, K.7
-
98
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y, Huang TT, Carlson EJ, Melvo S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP. Berge C, Chan PH, Wallace DC, Epstein CJ. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 11:376-381, 1995.
-
(1995)
Nat Genet
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melvo, S.4
Ursell, P.C.5
Olson, J.L.6
Noble, L.J.7
Yoshimura, M.P.8
Berge, C.9
Chan, P.H.10
Wallace, D.C.11
Epstein, C.J.12
-
99
-
-
0024547664
-
Null mutation of copper/zinc superoxide dismutase in Drosophila confer hypersensitivity to paraquat and reduced longevity
-
Phillips JP, Campbell SD, Michaud D, Charbonneau M, Hilliker AJ. Null mutation of copper/zinc superoxide dismutase in Drosophila confer hypersensitivity to paraquat and reduced longevity. Proc Natl Acad Sci USA 86:2761-2765, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2761-2765
-
-
Phillips, J.P.1
Campbell, S.D.2
Michaud, D.3
Charbonneau, M.4
Hilliker, A.J.5
-
100
-
-
0027284743
-
Molecular characterization and rescue of acatalasemic mutants of Drosoplila melanogaster
-
Griswold CM, Matthews AL, Bewley KE, Mahaffey JW. Molecular characterization and rescue of acatalasemic mutants of Drosoplila melanogaster. Genetics 134:781-788, 1993.
-
(1993)
Genetics
, vol.134
, pp. 781-788
-
-
Griswold, C.M.1
Matthews, A.L.2
Bewley, K.E.3
Mahaffey, J.W.4
-
101
-
-
0027293919
-
Effects of Cu-Zn superoxide dismutase overexpression of life span and resistance to oxidative stress in transgenic Drosophila melanogaster
-
Orr WC, Sohal RS. Effects of Cu-Zn superoxide dismutase overexpression of life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch Biochem Biophys 301:34-40, 1993.
-
(1993)
Arch Biochem Biophys
, vol.301
, pp. 34-40
-
-
Orr, W.C.1
Sohal, R.S.2
-
102
-
-
0032442835
-
Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice
-
Lee CM, Aspnes LE, Chung SS, Weindruch R, Aiken JM. Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice. Ann NY Acad Sci 854:182-191, 1998.
-
(1998)
Ann NY Acad Sci
, vol.854
, pp. 182-191
-
-
Lee, C.M.1
Aspnes, L.E.2
Chung, S.S.3
Weindruch, R.4
Aiken, J.M.5
-
103
-
-
0032423013
-
The effects of dietary restriction on mitochondrial dysfunction in aging
-
Feuers RJ. The effects of dietary restriction on mitochondrial dysfunction in aging. Ann NY Acad Sci 854:192-201, 1998.
-
(1998)
Ann NY Acad Sci
, vol.854
, pp. 192-201
-
-
Feuers, R.J.1
-
104
-
-
0002026429
-
Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin
-
Lu CY, Lee HC, Fahn HJ, Wei YH. Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin. Mutat Res 423:11-21, 1999.
-
(1999)
Mutat Res
, vol.423
, pp. 11-21
-
-
Lu, C.Y.1
Lee, H.C.2
Fahn, H.J.3
Wei, Y.H.4
-
105
-
-
0025885770
-
Replication and transcription of vertebrate mitochondrial DNA
-
Clayton DA. Replication and transcription of vertebrate mitochondrial DNA. Annu Rev Cell Biol 7:453-478, 1991.
-
(1991)
Annu Rev Cell Biol
, vol.7
, pp. 453-478
-
-
Clayton, D.A.1
-
106
-
-
0023947327
-
Evidence for mitochondrial DNA damage by lipid peroxidation
-
Hruszkewycz AM. Evidence for mitochondrial DNA damage by lipid peroxidation. Biochem Biophys Res Commun 153:191-197, 1988.
-
(1988)
Biochem Biophys Res Commun
, vol.153
, pp. 191-197
-
-
Hruszkewycz, A.M.1
-
107
-
-
0026784592
-
Lipid peroxidation and mtDNA degeneration. A hypothesis
-
Hruszkewycz AM. Lipid peroxidation and mtDNA degeneration. A hypothesis. Mutat Res 275:243-248, 1992.
-
(1992)
Mutat Res
, vol.275
, pp. 243-248
-
-
Hruszkewycz, A.M.1
-
108
-
-
0029116061
-
Oxidative damage to mitochondrial DNA and its relationship to ageing
-
Richter C. Oxidative damage to mitochondrial DNA and its relationship to ageing. Int J Biochem Cell Biol 27:647-653, 1995.
-
(1995)
Int J Biochem Cell Biol
, vol.27
, pp. 647-653
-
-
Richter, C.1
-
109
-
-
0027249351
-
A deletion of mitochondrial DNA in murine doxorubicin-induced cardiotoxicity
-
Adachi K, Fujiura Y, Mayumi F, Nozuhara A, Sugiu Y, Sakanashi T, Hidaka T, Toshima H. A deletion of mitochondrial DNA in murine doxorubicin-induced cardiotoxicity. Biochem Biophys Res Commun 195:945-951, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.195
, pp. 945-951
-
-
Adachi, K.1
Fujiura, Y.2
Mayumi, F.3
Nozuhara, A.4
Sugiu, Y.5
Sakanashi, T.6
Hidaka, T.7
Toshima, H.8
-
110
-
-
0032514466
-
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
-
Ishii N, Fujii M, Hartman PS, Tsuda M, Yasuda K, Senoo-Matsuda N, Yanase S, Ayusawa D, Suzuki K. A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. Nature 394:695-697, 1998.
-
(1998)
Nature
, vol.394
, pp. 695-697
-
-
Ishii, N.1
Fujii, M.2
Hartman, P.S.3
Tsuda, M.4
Yasuda, K.5
Senoo-Matsuda, N.6
Yanase, S.7
Ayusawa, D.8
Suzuki, K.9
-
111
-
-
0029765459
-
The unusual structures of the hot-regions flanking large-scale deletions in human mitochondrial DNA
-
Hou JH, Wei YH. The unusual structures of the hot-regions flanking large-scale deletions in human mitochondrial DNA. Biochem J 318:1065-1070, 1996.
-
(1996)
Biochem J
, vol.318
, pp. 1065-1070
-
-
Hou, J.H.1
Wei, Y.H.2
-
112
-
-
0028837939
-
A topoisomerase II cleavage site is associated with a novel mitochondrial DNA deletion
-
Blok RB, Thorburn DR, Thompson GN, Dahl HHM. A topoisomerase II cleavage site is associated with a novel mitochondrial DNA deletion. Hum Genet 95:75-81, 1995.
-
(1995)
Hum Genet
, vol.95
, pp. 75-81
-
-
Blok, R.B.1
Thorburn, D.R.2
Thompson, G.N.3
Dahl, H.H.M.4
-
113
-
-
0028227936
-
Mitochondrial encephalomyopathies: Clinical and molecular analysis
-
Schon EA, Hirano M, DiMauro S. Mitochondrial encephalomyopathies: clinical and molecular analysis. J Bioenerg Biomembr 26:291-299, 1994.
-
(1994)
J Bioenerg Biomembr
, vol.26
, pp. 291-299
-
-
Schon, E.A.1
Hirano, M.2
DiMauro, S.3
-
114
-
-
0032541048
-
AT-rich sequences flanking the 5′-end breakpoint of the 4977-bp deletion of human mitochondrial DNA are located between two bent-inducing DNA sequences that assume distorted structure in organello
-
Hou JH, Wei YH. AT-rich sequences flanking the 5′-end breakpoint of the 4977-bp deletion of human mitochondrial DNA are located between two bent-inducing DNA sequences that assume distorted structure in organello. Mutat Res 403:75-84, 1998.
-
(1998)
Mutat Res
, vol.403
, pp. 75-84
-
-
Hou, J.H.1
Wei, Y.H.2
-
115
-
-
0032967444
-
Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: Studies in vivo and in vitro
-
Esteve JM, Mompo J. García de la Asunción J, Sastre J, Asensi M, Boix J, Viña J, Pallardó FV. Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro. FASEB J 13:1055-1064, 1999.
-
(1999)
FASEB J
, vol.13
, pp. 1055-1064
-
-
Esteve, J.M.1
Mompo, J.2
García de la Asunción, J.3
Sastre, J.4
Asensi, M.5
Boix, J.6
Viña, J.7
Pallardó, F.V.8
-
116
-
-
0027983133
-
Oxygen radical induced mutagenesis is DNA polymerase specific
-
Felg DI, Loeb LA. Oxygen radical induced mutagenesis is DNA polymerase specific. J Mol Biol 235:33-41, 1994.
-
(1994)
J Mol Biol
, vol.235
, pp. 33-41
-
-
Felg, D.I.1
Loeb, L.A.2
-
117
-
-
0033963144
-
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast
-
Dumont P, Burton M, Chen QM, Gonos ES, Frippiat C, Mazarati JB, Eliaers F, Remacle J, Toussaint O. Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast. Free Radic Biol Med 28:361-373, 2000.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 361-373
-
-
Dumont, P.1
Burton, M.2
Chen, Q.M.3
Gonos, E.S.4
Frippiat, C.5
Mazarati, J.B.6
Eliaers, F.7
Remacle, J.8
Toussaint, O.9
-
118
-
-
0027941299
-
Human skin mitochondrial DNA deletions associated with light exposure
-
Pang CY, Lee HC, Yang JH, Wei YH. Human skin mitochondrial DNA deletions associated with light exposure. Arch Biochem Biophys 312:534-538, 1994.
-
(1994)
Arch Biochem Biophys
, vol.312
, pp. 534-538
-
-
Pang, C.Y.1
Lee, H.C.2
Yang, J.H.3
Wei, Y.H.4
-
119
-
-
0033016467
-
Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion
-
Berneburg M, Grether-Beck S, Kurten V, Ruzicka T, Briviba K, Sies H, Krutmann J. Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion. J Biol Chem 274:15345-15349, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 15345-15349
-
-
Berneburg, M.1
Grether-Beck, S.2
Kurten, V.3
Ruzicka, T.4
Briviba, K.5
Sies, H.6
Krutmann, J.7
-
120
-
-
0032247061
-
Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues
-
Fahn HJ, Wang LS, Kao SH, Chang SC, Huang MH, Wei YH. Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues. Am J Respir Cell Mol Biol 19:901-909, 1998.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 901-909
-
-
Fahn, H.J.1
Wang, L.S.2
Kao, S.H.3
Chang, S.C.4
Huang, M.H.5
Wei, Y.H.6
-
121
-
-
0030806434
-
Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients
-
Mansouri A, Fromenty B, Berson A, Robin MA, Grimbert S, Beaugrand M, Erlinger S, Pessayre D. Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients. J Hepatol 27:96-102, 1997.
-
(1997)
J Hepatol
, vol.27
, pp. 96-102
-
-
Mansouri, A.1
Fromenty, B.2
Berson, A.3
Robin, M.A.4
Grimbert, S.5
Beaugrand, M.6
Erlinger, S.7
Pessayre, D.8
-
122
-
-
0035958278
-
Accumulation of mitochondrial DNA deletions in human oral tissues: Effects of betel quid chewing and oral cancer
-
Lee HC, Yin PH, Yu TN, Chang YD, Hsu WC, Kao SY, Chi CW, Liu TY, Wei YH. Accumulation of mitochondrial DNA deletions in human oral tissues: effects of betel quid chewing and oral cancer. Mutat Res 493:67-74, 2001.
-
(2001)
Mutat Res
, vol.493
, pp. 67-74
-
-
Lee, H.C.1
Yin, P.H.2
Yu, T.N.3
Chang, Y.D.4
Hsu, W.C.5
Kao, S.Y.6
Chi, C.W.7
Liu, T.Y.8
Wei, Y.H.9
-
123
-
-
0035978154
-
Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system
-
Wei YH, Lu CY, Wei CY, Ma YS, Lee HC. Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system. Chinese J Physiol 44:1-11, 2001.
-
(2001)
Chinese J Physiol
, vol.44
, pp. 1-11
-
-
Wei, Y.H.1
Lu, C.Y.2
Wei, C.Y.3
Ma, Y.S.4
Lee, H.C.5
-
124
-
-
0027324378
-
Mutagenesis by 8-oxoguanine: An enemy within
-
Grollman AP, Moriya M. Mutagenesis by 8-oxoguanine: an enemy within. Trends Genet 9:246-249, 1993.
-
(1993)
Trends Genet
, vol.9
, pp. 246-249
-
-
Grollman, A.P.1
Moriya, M.2
-
125
-
-
0032526616
-
Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage
-
Takao M, Aburatani H, Kobayashi K, Yasui A. Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage. Nucleic Acids Res 26:2917-2922, 1998.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 2917-2922
-
-
Takao, M.1
Aburatani, H.2
Kobayashi, K.3
Yasui, A.4
-
126
-
-
0024241304
-
Mitochondrial endonuclease activities specific for apurinic/apyrimidinic sites in DNA from mouse cells
-
Tomkinson AE, Bonk RT, Linn S. Mitochondrial endonuclease activities specific for apurinic/apyrimidinic sites in DNA from mouse cells. J Biol Chem 263:12532-12537, 1988.
-
(1988)
J Biol Chem
, vol.263
, pp. 12532-12537
-
-
Tomkinson, A.E.1
Bonk, R.T.2
Linn, S.3
-
127
-
-
0030777362
-
An oxidative damage-specific endonuclease from rat liver mitochondria
-
Croteau DL, ap Rhys CMJ, Hudson EK, Dianov GL, Hansford RG, Bohr VA. An oxidative damage-specific endonuclease from rat liver mitochondria. J Biol Chem 272:27338-27344, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 27338-27344
-
-
Croteau, D.L.1
Ap Rhys, C.M.J.2
Hudson, E.K.3
Dianov, G.L.4
Hansford, R.G.5
Bohr, V.A.6
-
128
-
-
0033561246
-
Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria
-
Souza-Pinto NC, Croteau DL, Hudson EK, Hansford RG, Bohr AA. Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria. Nucleic Acids Res 27:1935-1942, 1999.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 1935-1942
-
-
Souza-Pinto, N.C.1
Croteau, D.L.2
Hudson, E.K.3
Hansford, R.G.4
Bohr, A.A.5
-
129
-
-
0028980982
-
Intracellular localization of 8-oxodGTPase in human cells, with special reference to the role of the enzyme in mitochondria
-
Kang D, Nishida J, Iyama A, Nakabeppu Y, Furuichi M, Fujiwara T, Sekiguchi M, Takeshige K. Intracellular localization of 8-oxodGTPase in human cells, with special reference to the role of the enzyme in mitochondria. J Biol Chem 270:14659-14665, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 14659-14665
-
-
Kang, D.1
Nishida, J.2
Iyama, A.3
Nakabeppu, Y.4
Furuichi, M.5
Fujiwara, T.6
Sekiguchi, M.7
Takeshige, K.8
-
130
-
-
0029911367
-
Mammalian mitochondrial possess homologous DNA recombination activity
-
Thyagarajan B, Padua RA, Campbell C. Mammalian mitochondrial possess homologous DNA recombination activity. J Biol Chem 271:27536-27543, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 27536-27543
-
-
Thyagarajan, B.1
Padua, R.A.2
Campbell, C.3
-
131
-
-
0026493929
-
Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells
-
LeDoux SP, Wilson GL, Beecham EJ, Stevnsner T, Wassermann K, Bohr VA. Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells. Carcinogenesis 13:1967-1973, 1992.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1967-1973
-
-
LeDoux, S.P.1
Wilson, G.L.2
Beecham, E.J.3
Stevnsner, T.4
Wassermann, K.5
Bohr, V.A.6
-
132
-
-
0000825475
-
The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria
-
Clayton DA, Doda JN, Friedberg EC. The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. Proc Natl Acad Sci USA 71:2777-2781, 1974.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 2777-2781
-
-
Clayton, D.A.1
Doda, J.N.2
Friedberg, E.C.3
-
133
-
-
0026672644
-
Gene- and strand-specific damage and repair in Chinese hamster ovary cells treated with 4-nitroquinoline 1-oxide
-
Snyderwine EG, Bohr VA. Gene- and strand-specific damage and repair in Chinese hamster ovary cells treated with 4-nitroquinoline 1-oxide. Cancer Res 52:4183-4189, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 4183-4189
-
-
Snyderwine, E.G.1
Bohr, V.A.2
-
134
-
-
0029892790
-
DNA excision repair
-
Sancer A. DNA excision repair. Annu Rev Biochem 65:43-81, 1996.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 43-81
-
-
Sancer, A.1
-
135
-
-
0028827265
-
Age-associated change of 8-hydroxyguanine repair activity in cultured human fibroblasts
-
Hirano T, Yamaguchi Y, Hirano H, Kasai H. Age-associated change of 8-hydroxyguanine repair activity in cultured human fibroblasts. Biochem Biophys Res Commun 214:1157-1162, 1995.
-
(1995)
Biochem Biophys Res Commun
, vol.214
, pp. 1157-1162
-
-
Hirano, T.1
Yamaguchi, Y.2
Hirano, H.3
Kasai, H.4
-
136
-
-
0029878894
-
Defective repair of oxidative damage in the mitochondrial DNA of a Xeroderma pigmentosum group A cell line
-
Driggers WJ, Grishko VI, LeDoux SP, Wilson GL. Defective repair of oxidative damage in the mitochondrial DNA of a Xeroderma pigmentosum group A cell line. Cancer Res 56:1262-1266, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 1262-1266
-
-
Driggers, W.J.1
Grishko, V.I.2
LeDoux, S.P.3
Wilson, G.L.4
-
137
-
-
0033902601
-
Aging enhances the activation of permeability transition pore in mitochondria
-
Mather M, Rottenberg H. Aging enhances the activation of permeability transition pore in mitochondria. Biochem Biophys Res Commun 273:603-608, 2000.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 603-608
-
-
Mather, M.1
Rottenberg, H.2
-
138
-
-
0032032941
-
Intracellular calcium. Dnase activity and myocyte apoptosis in aging Fischer 344 rats
-
Nitahara JM, Cheng W, Liu Y, Li B, Leri A, Li P, Mogul D, Gambert SR, Kajatura J, Anversa P. Intracellular calcium. Dnase activity and myocyte apoptosis in aging Fischer 344 rats. J Mol Cell Cardiol 30:519-535, 1998.
-
(1998)
J Mol Cell Cardiol
, vol.30
, pp. 519-535
-
-
Nitahara, J.M.1
Cheng, W.2
Liu, Y.3
Li, B.4
Leri, A.5
Li, P.6
Mogul, D.7
Gambert, S.R.8
Kajatura, J.9
Anversa, P.10
-
139
-
-
0027417262
-
Cardiovascular regulatory mechanisms in advanced age
-
Lakatta EG. Cardiovascular regulatory mechanisms in advanced age. Physiol Rev 73:413-467, 1993.
-
(1993)
Physiol Rev
, vol.73
, pp. 413-467
-
-
Lakatta, E.G.1
-
141
-
-
0029039799
-
Age-related changes in the intrinsic rate of apoptosis in livers of diet-restricted and ad libitum-fed B 6C3F1 mice
-
Muskhelishvili L, Hart RW, Turturro A, James SJ. Age-related changes in the intrinsic rate of apoptosis in livers of diet-restricted and ad libitum-fed B6C3F1 mice. Am J Pathol 147:20-24, 1995.
-
(1995)
Am J Pathol
, vol.147
, pp. 20-24
-
-
Muskhelishvili, L.1
Hart, R.W.2
Turturro, A.3
James, S.J.4
-
142
-
-
0030698871
-
Life and death of neurons in the aging brain
-
Morrison JH, Hof PR. Life and death of neurons in the aging brain. Science 278:412-419, 1997.
-
(1997)
Science
, vol.278
, pp. 412-419
-
-
Morrison, J.H.1
Hof, P.R.2
-
143
-
-
0008235624
-
Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats
-
Kajstura J, Cheng W, Sarangarajan R, Li P, Li B, Nitahara JA, Chapnick S, Reiss K, Olivetti G, Anversa P. Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol Heart Circ Physiol 271:H1215-HI228, 1996.
-
(1996)
Am J Physiol Heart Circ Physiol
, vol.271
-
-
Kajstura, J.1
Cheng, W.2
Sarangarajan, R.3
Li, P.4
Li, B.5
Nitahara, J.A.6
Chapnick, S.7
Reiss, K.8
Olivetti, G.9
Anversa, P.10
-
144
-
-
0025105752
-
Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart
-
Anversa P, Palackal T, Sonnenblick EH, Olivetti G, Meggs LG, Capasso JM. Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart. Circ Res 67:871-885, 1990.
-
(1990)
Circ Res
, vol.67
, pp. 871-885
-
-
Anversa, P.1
Palackal, T.2
Sonnenblick, E.H.3
Olivetti, G.4
Meggs, L.G.5
Capasso, J.M.6
-
145
-
-
0025801813
-
Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy
-
Olivetti G, Melissari M, Capasso JM, Anversa P. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ Res 68:1560-1568, 1991.
-
(1991)
Circ Res
, vol.68
, pp. 1560-1568
-
-
Olivetti, G.1
Melissari, M.2
Capasso, J.M.3
Anversa, P.4
-
146
-
-
0036081753
-
Cytochrome c release from mitochondria in the aging heart: A possible mechanism for apoptosis with age
-
Phaneuf S, Leeuwenburgh C. Cytochrome c release from mitochondria in the aging heart: a possible mechanism for apoptosis with age. Am J Physiol Regul Integrative Comp Physiol 282:R423-R430, 2002.
-
(2002)
Am J Physiol Regul Integrative Comp Physiol
, vol.282
-
-
Phaneuf, S.1
Leeuwenburgh, C.2
-
148
-
-
0033107840
-
Aging splenocyte and thymocyte apoptosis is associated with enhanced expression of p53, Bax, and caspase-3
-
Kapasi AA, Singhal PC. Aging splenocyte and thymocyte apoptosis is associated with enhanced expression of p53, Bax, and caspase-3. Mol Cell Biol Res Commun 1:78-81, 1999.
-
(1999)
Mol Cell Biol Res Commun
, vol.1
, pp. 78-81
-
-
Kapasi, A.A.1
Singhal, P.C.2
-
149
-
-
10144256482
-
DNA fragmentation of oocytes in aged mice
-
Fujino Y, Ozaki K, Yamamasu S, Ito F, Matsuoka I, Hayashi E, Nakamura H, Ogita S, Sato E, Inoue M. DNA fragmentation of oocytes in aged mice. Hum Reprod 11:1480-1483, 1996.
-
(1996)
Hum Reprod
, vol.11
, pp. 1480-1483
-
-
Fujino, Y.1
Ozaki, K.2
Yamamasu, S.3
Ito, F.4
Matsuoka, I.5
Hayashi, E.6
Nakamura, H.7
Ogita, S.8
Sato, E.9
Inoue, M.10
-
150
-
-
0032501043
-
Differential expression of rat brain Bcl-2 family proteins in development and aging
-
Shimohama S, Fujimoto S, Sumida Y, Tanino H. Differential expression of rat brain Bcl-2 family proteins in development and aging. Biochem Biophys Res Commun 252:92-96, 1998.
-
(1998)
Biochem Biophys Res Commun
, vol.252
, pp. 92-96
-
-
Shimohama, S.1
Fujimoto, S.2
Sumida, Y.3
Tanino, H.4
-
151
-
-
0035930899
-
Differential expression of rat brain caspase family proteins during development and aging
-
Shimohama S, Tanino H, Fujimoto S. Differential expression of rat brain caspase family proteins during development and aging. Biochem Biophys Res Commun 289:1063-1066, 2001.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 1063-1066
-
-
Shimohama, S.1
Tanino, H.2
Fujimoto, S.3
-
152
-
-
0034857113
-
Aging is associated with increased proliferation and decreased apoptosis in the colonic mucosa
-
Xiao ZQ, Moragoda L, Jaszewski R, Hatfield JA, Fligiel SEG, Majumdar APN. Aging is associated with increased proliferation and decreased apoptosis in the colonic mucosa. Mech Ageing Dev 122:1849-1864, 2001.
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 1849-1864
-
-
Xiao, Z.Q.1
Moragoda, L.2
Jaszewski, R.3
Hatfield, J.A.4
Fligiel, S.E.G.5
Majumdar, A.P.N.6
-
153
-
-
0036154895
-
Aging alters the apoptotic response to genotoxic stress
-
Suh Y, Lee KA, Kim WH, Han BG, Vijg J, Park SC. Aging alters the apoptotic response to genotoxic stress. Nat Med 8:3-4, 2002.
-
(2002)
Nat Med
, vol.8
, pp. 3-4
-
-
Suh, Y.1
Lee, K.A.2
Kim, W.H.3
Han, B.G.4
Vijg, J.5
Park, S.C.6
-
154
-
-
0030465635
-
Mitochondrial genetics and human disease
-
Grossman LI, Shoubridge EA. Mitochondrial genetics and human disease. BioEssays 18:983-991, 1996.
-
(1996)
BioEssays
, vol.18
, pp. 983-991
-
-
Grossman, L.I.1
Shoubridge, E.A.2
-
155
-
-
0033964762
-
Mitochondrial role in life and death of the cell
-
Lee HC, Wei YH. Mitochondrial role in life and death of the cell. J Biomed Sci 7:2-15, 2000.
-
(2000)
J Biomed Sci
, vol.7
, pp. 2-15
-
-
Lee, H.C.1
Wei, Y.H.2
-
156
-
-
0022650598
-
Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle
-
Williams RS, Salmons S, Newsholme EA, Kaufman RE, Mellor J. Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle. J Biol Chem 261:376-380, 1986.
-
(1986)
J Biol Chem
, vol.261
, pp. 376-380
-
-
Williams, R.S.1
Salmons, S.2
Newsholme, E.A.3
Kaufman, R.E.4
Mellor, J.5
-
157
-
-
0030881873
-
Electrical stimulation of neonatal cardiomyocytes results in the sequential activation of nuclear genes governing mitochondrial proliferation and differentiation
-
Xia Y, Buja LM, Scarpulla RC, McMillin JB. Electrical stimulation of neonatal cardiomyocytes results in the sequential activation of nuclear genes governing mitochondrial proliferation and differentiation. Proc Natl Acad Sci USA 94:11399-11404, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11399-11404
-
-
Xia, Y.1
Buja, L.M.2
Scarpulla, R.C.3
McMillin, J.B.4
-
158
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 90:791-7922, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 791-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
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