Aging-related occurrence in Ashkenazi Jews of leukocyte heteroplasmic mtDNA mutation adjacent to replication origin frequently remodeled in Italian centenarians

Mitochondrion

Volumn 7, Issue 4, 2007, Pages 267-272

  Iwata, Nahoko ^a   Zhang, Jin ^a   Atzmon, Gil ^b   Leanza, Suzanne ^b   Cho, Jaehyoung ^a   Chomyn, Anne ^a   Burk, Robert D ^b   Barzilai, Nir ^b   Attardi, Giuseppe ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Longevity; mtDNA replication; Primer extension; Replication origins

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; AGED; AGING; ARTICLE; CONTROLLED STUDY; DNA REPLICATION ORIGIN; FEMALE; GENE FREQUENCY; GENE MUTATION; GENE REPLICATION; GENETIC ASSOCIATION; HETEROPLASMY; HUMAN; HUMAN CELL; INCIDENCE; ITALY; JEW; LEUKOCYTE; LONGEVITY; MALE; POPULATION GENETICS; PRIORITY JOURNAL; PROGENY;

ADULT; AGED; AGED, 80 AND OVER; AGING; DNA, MITOCHONDRIAL; FEMALE; HUMANS; ITALY; JEWS; LEUKOCYTES; MALE; MIDDLE AGED; MITOCHONDRIAL DISEASES; MUTATION; REPLICATION ORIGIN;

EID: 34249050431     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2007.03.001     Document Type: Article

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