-
1
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
Bunn HF, Poyton RO: Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76:839, 1996
-
(1996)
Physiol Rev
, vol.76
, pp. 839
-
-
Bunn, H.F.1
Poyton, R.O.2
-
2
-
-
0027461553
-
Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: Evidence for a widespread oxygen sensing mechanism
-
Maxwell PH, Pugh CW, Ratcliffe PJ: Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: Evidence for a widespread oxygen sensing mechanism. Proc Natl Acad Sci USA 90:2423, 1993
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2423
-
-
Maxwell, P.H.1
Pugh, C.W.2
Ratcliffe, P.J.3
-
3
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza GL, Wang GL: A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12:5447, 1992
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447
-
-
Semenza, G.L.1
Wang, G.L.2
-
5
-
-
0031969042
-
Hypoxia and the regulation of gene expression
-
Gleadle JM, Ratcliffe PJ: Hypoxia and the regulation of gene expression. Mol Med Today 4:122, 1998
-
(1998)
Mol Med Today
, vol.4
, pp. 122
-
-
Gleadle, J.M.1
Ratcliffe, P.J.2
-
6
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily on redoxsensitive stabilization of its a subunit
-
Huang LE, Arany Z, Livingston DM, Bunn HF: Activation of hypoxia-inducible transcription factor depends primarily on redoxsensitive stabilization of its a subunit. J Biol Chem 271:32253, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 32253
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
7
-
-
0030961006
-
Hypoxia-inducible factor la (HIF-lα) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions
-
Salceda S, Caro J: Hypoxia-inducible factor la (HIF-lα) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. J Biol Chem 272:22642, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 22642
-
-
Salceda, S.1
Caro, J.2
-
8
-
-
0030937718
-
Activation of hypoxia inducible factor-1; definition of regulatory domains within the α subunit
-
Pugh CW. O'Rourke JF, Nagao M, Gleadle JM, Ratcliffe PJ: Activation of hypoxia inducible factor-1; definition of regulatory domains within the α subunit. J Biol Chem 272:11205, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 11205
-
-
Pugh, C.W.1
O'Rourke, J.F.2
Nagao, M.3
Gleadle, J.M.4
Ratcliffe, P.J.5
-
9
-
-
0032493368
-
Regulation of hypoxiainducible factor lα is mediated by an oxygen-dependent domain via the ubiquitin-proteasome pathway
-
Huang LE, Gu J, Schau M, Bunn HF: Regulation of hypoxiainducible factor lα is mediated by an oxygen-dependent domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 95:7987, 1998
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7987
-
-
Huang, L.E.1
Gu, J.2
Schau, M.3
Bunn, H.F.4
-
10
-
-
0032030839
-
Control of cell lineage-specific development and transcription by bHLH-PAS proteins
-
Crews ST: Control of cell lineage-specific development and transcription by bHLH-PAS proteins. Genes Dev 12:607, 1998
-
(1998)
Genes Dev
, vol.12
, pp. 607
-
-
Crews, S.T.1
-
11
-
-
0031020884
-
Endothelial PAS domain protein l (EPAS1), a transcription factor selectively expressed in endothehal cells
-
Tian H, McKnight SL, Russell DW: Endothelial PAS domain protein l (EPAS1), a transcription factor selectively expressed in endothehal cells. Genes Dev 11:72, 1997
-
(1997)
Genes Dev
, vol.11
, pp. 72
-
-
Tian, H.1
McKnight, S.L.2
Russell, D.W.3
-
12
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor lα regulates the VEGF expression and is potentially involved in lung and vascular development
-
Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii- KurdistanKuriyama Y: A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor lα regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci USA 94:4273, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4273
-
-
Ema, M.1
Taya, S.2
Yokotani, N.3
Sogawa, K.4
Matsuda, Y.5
Fujii- KurdistanKuriyama, Y.6
-
13
-
-
0030887045
-
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway
-
Hogenesch JB, Chan WK, Jackiw VH, Brown RC, Gu Y-Z, Pray-Grant M, Perdew GH, Bradfield CA: Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J Biol Chem 272:8581, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 8581
-
-
Hogenesch, J.B.1
Chan, W.K.2
Jackiw, V.H.3
Brown, R.C.4
Gu, Y.-Z.5
Pray-Grant, M.6
Perdew, G.H.7
Bradfield, C.A.8
-
14
-
-
0343683375
-
HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-la and developmentally expressed in blood vessels
-
Flamme I, Fröhlich T, von Reutern M, Kappel A, Damert A, Risau W: HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-la and developmentally expressed in blood vessels. Mech Dev 63:51, 1997
-
(1997)
Mech Dev
, vol.63
, pp. 51
-
-
Flamme, I.1
Fröhlich, T.2
Von Reutern, M.3
Kappel, A.4
Damert, A.5
Risau, W.6
-
15
-
-
0032478823
-
Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 α-subunit (HIF-lα)
-
Wood SM, Wiesener MS, Yeates KM, Okada N, Pugh CW, Maxwell PH, Ratcliffe PJ: Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 α-subunit (HIF-lα). J Biol Chem 273:8360, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 8360
-
-
Wood, S.M.1
Wiesener, M.S.2
Yeates, K.M.3
Okada, N.4
Pugh, C.W.5
Maxwell, P.H.6
Ratcliffe, P.J.7
-
16
-
-
0026677532
-
HMEC-1: Establishment of an immortalized human microvascular endothelial cell line
-
Ades EW, Candal FJ, Swerlick RA, George VG, Summers S, Bosse DC, Lawley TJ: HMEC-1: Establishment of an immortalized human microvascular endothelial cell line. J Invest Dermatol 99:683, 1992
-
(1992)
J Invest Dermatol
, vol.99
, pp. 683
-
-
Ades, E.W.1
Candal, F.J.2
Swerlick, R.A.3
George, V.G.4
Summers, S.5
Bosse, D.C.6
Lawley, T.J.7
-
17
-
-
0028359320
-
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoeitin 3′ enhancer
-
Firth JD, Ebert BL, Pugh CW, Ratcliffe PJ: Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoeitin 3′ enhancer. Proc Natl Acad Sci USA 91:6496, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6496
-
-
Firth, J.D.1
Ebert, B.L.2
Pugh, C.W.3
Ratcliffe, P.J.4
-
18
-
-
0030914648
-
Activation of hypoxia-inducible factor lα: Posttranscriptional regulation and conformational change by recruitment of the Amt transcription factor
-
Kallio PJ, Pongratz I, Gradin K, McGuire J, Poellinger L: Activation of hypoxia-inducible factor lα: Posttranscriptional regulation and conformational change by recruitment of the Amt transcription factor. Proc Natl Acad Sci USA 94:5667, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5667
-
-
Kallio, P.J.1
Pongratz, I.2
Gradin, K.3
McGuire, J.4
Poellinger, L.5
-
19
-
-
0024273450
-
Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein
-
Goldberg MA, Dunning SP, Bunn HF: Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein. Science 242:1412, 1988
-
(1988)
Science
, vol.242
, pp. 1412
-
-
Goldberg, M.A.1
Dunning, S.P.2
Bunn, H.F.3
-
20
-
-
0027136260
-
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
-
Wang GL, Semcnza GL: Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction. Blood 82:3610, 1993
-
(1993)
Blood
, vol.82
, pp. 3610
-
-
Wang, G.L.1
Semcnza, G.L.2
-
21
-
-
0015333307
-
Unresponsiveness of erythropoietinprdducing cells to cyanide
-
Necas E, Thorling EB: Unresponsiveness of erythropoietinprdducing cells to cyanide. Am J Physiol 222:1187, 1972
-
(1972)
Am J Physiol
, vol.222
, pp. 1187
-
-
Necas, E.1
Thorling, E.B.2
-
22
-
-
0027970536
-
Role of hydrogen peroxide in hypoxia-induced erythropoietin production
-
Fandrey J, Frede S, Jelkmann W: Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem J 303:507, 1994
-
(1994)
Biochem J
, vol.303
, pp. 507
-
-
Fandrey, J.1
Frede, S.2
Jelkmann, W.3
-
23
-
-
0028844810
-
Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia: Implications for the mechanism of oxygen sensing
-
Gleadle JM, Ebert BL, Ratcliffe PJ: Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia: Implications for the mechanism of oxygen sensing. Eur J Biochem 234:92, 1995
-
(1995)
Eur J Biochem
, vol.234
, pp. 92
-
-
Gleadle, J.M.1
Ebert, B.L.2
Ratcliffe, P.J.3
-
24
-
-
0029982422
-
Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-lα
-
Wenger RH, Rolfs A, Marti HH, Guénet J-L, Gassmann M: Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-lα. Biochem Biophys Res Commun 223:54, 1996
-
(1996)
Biochem Biophys Res Commun
, vol.223
, pp. 54
-
-
Wenger, R.H.1
Rolfs, A.2
Marti, H.H.3
Guénet, J.-L.4
Gassmann, M.5
-
25
-
-
0031038417
-
Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species
-
Fandrey J, Frede S, Ehleben W, Porwol T, Acker H, Jelkmann W: Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species. Kidney Int 51:492, 1997
-
(1997)
Kidney Int
, vol.51
, pp. 492
-
-
Fandrey, J.1
Frede, S.2
Ehleben, W.3
Porwol, T.4
Acker, H.5
Jelkmann, W.6
-
26
-
-
0030851024
-
The PAS domain confers target gene specificity of Drosophila bHLH/PAS proteins
-
Zelzer E, Wappner P, Shilo B-Z: The PAS domain confers target gene specificity of Drosophila bHLH/PAS proteins. Genes Dev 11: 2079, 1997
-
(1997)
Genes Dev
, vol.11
, pp. 2079
-
-
Zelzer, E.1
Wappner, P.2
Shilo, B.-Z.3
-
27
-
-
1842416574
-
Oxygen(es) and the hypoxiainducible factor-1
-
Wenger RH, Gassmann M: Oxygen(es) and the hypoxiainducible factor-1. Biol Chem 378:609, 1997
-
(1997)
Biol Chem
, vol.378
, pp. 609
-
-
Wenger, R.H.1
Gassmann, M.2
|