-
1
-
-
3943107573
-
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
-
Sancar A., et al. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73 (2004) 39-85
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 39-85
-
-
Sancar, A.1
-
2
-
-
33751419716
-
Surviving the breakup: the DNA damage checkpoint
-
Harrison J.C., and Haber J.E. Surviving the breakup: the DNA damage checkpoint. Annu. Rev. Genet. 40 (2006) 209-235
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 209-235
-
-
Harrison, J.C.1
Haber, J.E.2
-
3
-
-
33845627082
-
Cellular responses to DNA damage: one signal, multiple choices
-
Su T.T. Cellular responses to DNA damage: one signal, multiple choices. Annu. Rev. Genet. 40 (2006) 187-208
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 187-208
-
-
Su, T.T.1
-
4
-
-
0027421043
-
Loss of a yeast telomere: arrest, recovery and chromosome loss
-
Sandell L.L., and Zakian V.A. Loss of a yeast telomere: arrest, recovery and chromosome loss. Cell 75 (1993) 729-739
-
(1993)
Cell
, vol.75
, pp. 729-739
-
-
Sandell, L.L.1
Zakian, V.A.2
-
5
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist C.J., and Kastan M.B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421 (2003) 499-506
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
6
-
-
21244493496
-
Localization of checkpoint and repair proteins in eukaryotes
-
Lisby M., and Rothstein R. Localization of checkpoint and repair proteins in eukaryotes. Biochimie 87 (2005) 579-589
-
(2005)
Biochimie
, vol.87
, pp. 579-589
-
-
Lisby, M.1
Rothstein, R.2
-
7
-
-
33745607897
-
Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses
-
Zou Y., et al. Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses. J. Cell. Physiol. 208 (2006) 267-273
-
(2006)
J. Cell. Physiol.
, vol.208
, pp. 267-273
-
-
Zou, Y.1
-
8
-
-
33749134033
-
A dynamic model for replication protein A (RPA) function in DNA processing pathways
-
Fanning E., et al. A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res. 34 (2006) 4126-4137
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 4126-4137
-
-
Fanning, E.1
-
9
-
-
36949026694
-
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
-
Lee J.H., and Paull T.T. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene 26 (2007) 7741-7748
-
(2007)
Oncogene
, vol.26
, pp. 7741-7748
-
-
Lee, J.H.1
Paull, T.T.2
-
10
-
-
2042429168
-
Regulation of telomerase by telomeric proteins
-
Smogorzewska A., and de Lange T. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 73 (2004) 177-208
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 177-208
-
-
Smogorzewska, A.1
de Lange, T.2
-
11
-
-
0345169051
-
Getting to the end: telomerase access in yeast and humans
-
Vega L.R., et al. Getting to the end: telomerase access in yeast and humans. Nat. Rev. Mol. Cell Biol. 4 (2003) 948-959
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 948-959
-
-
Vega, L.R.1
-
12
-
-
34250841785
-
Replication and protection of telomeres
-
Verdun R.E., and Karlseder J. Replication and protection of telomeres. Nature 447 (2007) 924-931
-
(2007)
Nature
, vol.447
, pp. 924-931
-
-
Verdun, R.E.1
Karlseder, J.2
-
13
-
-
1842683257
-
T-loops and the origin of telomeres
-
de Lange T. T-loops and the origin of telomeres. Nat. Rev. Mol. Cell Biol. 5 (2004) 323-329
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 323-329
-
-
de Lange, T.1
-
14
-
-
33847675342
-
RPA-like proteins mediate yeast telomere function
-
Gao H., et al. RPA-like proteins mediate yeast telomere function. Nat. Struct. Mol. Biol. 14 (2007) 208-214
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 208-214
-
-
Gao, H.1
-
15
-
-
36749019586
-
Telomere dynamics in human cells
-
Baird D.M. Telomere dynamics in human cells. Biochimie 90 (2008) 116-121
-
(2008)
Biochimie
, vol.90
, pp. 116-121
-
-
Baird, D.M.1
-
16
-
-
0029953557
-
Evidence for a new step in telomere maintenance
-
Wellinger R.J., et al. Evidence for a new step in telomere maintenance. Cell 85 (1996) 423-433
-
(1996)
Cell
, vol.85
, pp. 423-433
-
-
Wellinger, R.J.1
-
17
-
-
0038360921
-
Telomerase: what are the Est proteins doing?
-
Taggart A.K., and Zakian V.A. Telomerase: what are the Est proteins doing?. Curr. Opin. Cell Biol. 15 (2003) 275-280
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 275-280
-
-
Taggart, A.K.1
Zakian, V.A.2
-
18
-
-
20144382152
-
Switching human telomerase on and off with hPOT1 protein in vitro
-
Lei M., et al. Switching human telomerase on and off with hPOT1 protein in vitro. J. Biol. Chem. 280 (2005) 20449-20456
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20449-20456
-
-
Lei, M.1
-
19
-
-
33846691378
-
The POT1-TPP1 telomere complex is a telomerase processivity factor
-
Wang F., et al. The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature 445 (2007) 506-510
-
(2007)
Nature
, vol.445
, pp. 506-510
-
-
Wang, F.1
-
20
-
-
33846692105
-
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase
-
Xin H., et al. TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase. Nature 445 (2007) 559-562
-
(2007)
Nature
, vol.445
, pp. 559-562
-
-
Xin, H.1
-
21
-
-
46049111249
-
-
Paeschke, K. et al. Cell cycle dependent regulation of telomere tethering in the nucleus. Nat. Struct. Mol. Biol. (in press)
-
Paeschke, K. et al. Cell cycle dependent regulation of telomere tethering in the nucleus. Nat. Struct. Mol. Biol. (in press)
-
-
-
-
22
-
-
0036712072
-
Human telomerase and its regulation
-
Cong Y.S., et al. Human telomerase and its regulation. Microbiol. Mol. Biol. Rev. 66 (2002) 407-425
-
(2002)
Microbiol. Mol. Biol. Rev.
, vol.66
, pp. 407-425
-
-
Cong, Y.S.1
-
23
-
-
0036362266
-
Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again
-
Forsyth N.R., et al. Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again. Differentiation 69 (2002) 188-197
-
(2002)
Differentiation
, vol.69
, pp. 188-197
-
-
Forsyth, N.R.1
-
24
-
-
46049085234
-
Telomere DNA replication, telomerase and human disease
-
DePamphilis M. (Ed), CSHL Press
-
Sealey D., et al. Telomere DNA replication, telomerase and human disease. In: DePamphilis M. (Ed). DNA Replication and Human Disease (2006), CSHL Press 561-592
-
(2006)
DNA Replication and Human Disease
, pp. 561-592
-
-
Sealey, D.1
-
25
-
-
33745660289
-
Telomerase and human Cancer
-
De Lange T., et al. (Ed), Cold Spring Harbor Laboratory Press
-
Shay J., and Wright W. Telomerase and human Cancer. In: De Lange T., et al. (Ed). Telomeres. 2nd edn (2006), Cold Spring Harbor Laboratory Press 81-108
-
(2006)
Telomeres. 2nd edn
, pp. 81-108
-
-
Shay, J.1
Wright, W.2
-
26
-
-
33748183271
-
Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency
-
Mozdy A.D., and Cech T.R. Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency. RNA 12 (2006) 1721-1737
-
(2006)
RNA
, vol.12
, pp. 1721-1737
-
-
Mozdy, A.D.1
Cech, T.R.2
-
27
-
-
34147095342
-
Protein composition of catalytically active human telomerase from immortal cells
-
Cohen S.B., et al. Protein composition of catalytically active human telomerase from immortal cells. Science 315 (2007) 1850-1853
-
(2007)
Science
, vol.315
, pp. 1850-1853
-
-
Cohen, S.B.1
-
28
-
-
34547854351
-
Concise review: telomere biology in normal and leukemic hematopoietic stem cells
-
Drummond M.W., et al. Concise review: telomere biology in normal and leukemic hematopoietic stem cells. Stem Cells 25 (2007) 1853-1861
-
(2007)
Stem Cells
, vol.25
, pp. 1853-1861
-
-
Drummond, M.W.1
-
29
-
-
0033518188
-
A telomerase component is defective in the human disease dyskeratosis congenita
-
Mitchell J.R., et al. A telomerase component is defective in the human disease dyskeratosis congenita. Nature 402 (1999) 551-555
-
(1999)
Nature
, vol.402
, pp. 551-555
-
-
Mitchell, J.R.1
-
30
-
-
33646533410
-
Telomerase deficiency and human disease
-
De Lange T., et al. (Ed), Cold Spring Harbor Laboratory Press
-
Dokal I., and Vulliamy T. Telomerase deficiency and human disease. In: De Lange T., et al. (Ed). Telomeres (2006), Cold Spring Harbor Laboratory Press
-
(2006)
Telomeres
-
-
Dokal, I.1
Vulliamy, T.2
-
31
-
-
34250614359
-
Adult-onset pulmonary fibrosis caused by mutations in telomerase
-
Tsakiri K.D., et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 7552-7557
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 7552-7557
-
-
Tsakiri, K.D.1
-
32
-
-
34047188508
-
Telomerase mutations in families with idiopathic pulmonary fibrosis
-
Armanios M.Y., et al. Telomerase mutations in families with idiopathic pulmonary fibrosis. N. Engl. J. Med. 356 (2007) 1317-1326
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 1317-1326
-
-
Armanios, M.Y.1
-
33
-
-
38049019132
-
Human diseases of telomerase dysfunction: insights into tissue aging
-
Garcia C.K., et al. Human diseases of telomerase dysfunction: insights into tissue aging. Nucleic Acids Res. 35 (2007) 7406-7416
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7406-7416
-
-
Garcia, C.K.1
-
34
-
-
0036677405
-
MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae
-
Enomoto S., et al. MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae. Mol. Biol. Cell 13 (2002) 2626-2638
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2626-2638
-
-
Enomoto, S.1
-
35
-
-
0036682516
-
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants
-
Maringele L., and Lydall D. EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev. 16 (2002) 1919-1933
-
(2002)
Genes Dev.
, vol.16
, pp. 1919-1933
-
-
Maringele, L.1
Lydall, D.2
-
36
-
-
0037341611
-
Short telomeres induce a DNA damage response in Saccharomyces cerevisiae
-
IJpma A.S., and Greider C.W. Short telomeres induce a DNA damage response in Saccharomyces cerevisiae. Mol. Biol. Cell 14 (2003) 987-1001
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 987-1001
-
-
IJpma, A.S.1
Greider, C.W.2
-
37
-
-
34548317418
-
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
-
Denchi E.L., and de Lange T. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 448 (2007) 1068-1071
-
(2007)
Nature
, vol.448
, pp. 1068-1071
-
-
Denchi, E.L.1
de Lange, T.2
-
38
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
Takai H., et al. DNA damage foci at dysfunctional telomeres. Curr. Biol. 13 (2003) 1549-1556
-
(2003)
Curr. Biol.
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
-
39
-
-
38449085735
-
Telomere dysfunction, genome instability and cancer
-
Cheung A.L., and Deng W. Telomere dysfunction, genome instability and cancer. Front. Biosci. 13 (2008) 2075-2090
-
(2008)
Front. Biosci.
, vol.13
, pp. 2075-2090
-
-
Cheung, A.L.1
Deng, W.2
-
40
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna F., et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426 (2003) 194-198
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
-
41
-
-
3543056880
-
Functional links between telomeres and proteins of the DNA-damage response
-
d'Adda di Fagagna F., et al. Functional links between telomeres and proteins of the DNA-damage response. Genes Dev. 18 (2004) 1781-1799
-
(2004)
Genes Dev.
, vol.18
, pp. 1781-1799
-
-
d'Adda di Fagagna, F.1
-
42
-
-
33746691847
-
Cellular senescence and DNA repair
-
Lou Z., and Chen J. Cellular senescence and DNA repair. Exp. Cell Res. 312 (2006) 2641-2646
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 2641-2646
-
-
Lou, Z.1
Chen, J.2
-
43
-
-
0000393532
-
Identification of yeast mutants with altered telomere structure
-
Lustig A.J., and Petes T.D. Identification of yeast mutants with altered telomere structure. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 1398-1402
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 1398-1402
-
-
Lustig, A.J.1
Petes, T.D.2
-
44
-
-
0029088371
-
TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
-
Greenwell P.W., et al. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82 (1995) 823-829
-
(1995)
Cell
, vol.82
, pp. 823-829
-
-
Greenwell, P.W.1
-
45
-
-
0029150855
-
TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
-
Morrow D.M., et al. TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82 (1995) 831-840
-
(1995)
Cell
, vol.82
, pp. 831-840
-
-
Morrow, D.M.1
-
46
-
-
0032793298
-
Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
-
Ritchie K.B., et al. Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 19 (1999) 6065-6075
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6065-6075
-
-
Ritchie, K.B.1
-
47
-
-
0034610290
-
Protein kinase activity of tel1p and mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase
-
Mallory J.C., and Petes T.D. Protein kinase activity of tel1p and mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 13749-13754
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 13749-13754
-
-
Mallory, J.C.1
Petes, T.D.2
-
48
-
-
0035928740
-
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
-
Chan S.W., et al. Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Curr. Biol. 11 (2001) 1240-1250
-
(2001)
Curr. Biol.
, vol.11
, pp. 1240-1250
-
-
Chan, S.W.1
-
49
-
-
0035806977
-
The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres
-
Tsukamoto Y., et al. The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres. Curr. Biol. 11 (2001) 1328-1335
-
(2001)
Curr. Biol.
, vol.11
, pp. 1328-1335
-
-
Tsukamoto, Y.1
-
50
-
-
23844433614
-
Molecular basis of ataxia telangiectasia and related diseases
-
Ball L.G., and Xiao W. Molecular basis of ataxia telangiectasia and related diseases. Acta Pharmacol. Sin. 26 (2005) 897-907
-
(2005)
Acta Pharmacol. Sin.
, vol.26
, pp. 897-907
-
-
Ball, L.G.1
Xiao, W.2
-
51
-
-
29244437908
-
The role of double-strand break repair - insights from human genetics
-
O'Driscoll M., and Jeggo P.A. The role of double-strand break repair - insights from human genetics. Nat. Rev. Genet. 7 (2006) 45-54
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 45-54
-
-
O'Driscoll, M.1
Jeggo, P.A.2
-
52
-
-
33745823159
-
The ATM-mediated DNA-damage response: taking shape
-
Shiloh Y. The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31 (2006) 402-410
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 402-410
-
-
Shiloh, Y.1
-
53
-
-
3242886697
-
Telomeres and the DNA damage response: why the fox is guarding the henhouse
-
Maser R.S., and DePinho R.A. Telomeres and the DNA damage response: why the fox is guarding the henhouse. DNA Repair (Amst.) 3 (2004) 979-988
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 979-988
-
-
Maser, R.S.1
DePinho, R.A.2
-
54
-
-
0342561644
-
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
-
Zhu X.D., et al. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat. Genet. 25 (2000) 347-352
-
(2000)
Nat. Genet.
, vol.25
, pp. 347-352
-
-
Zhu, X.D.1
-
55
-
-
0043133869
-
Role of mammalian Rad54 in telomere length maintenance
-
Jaco I., et al. Role of mammalian Rad54 in telomere length maintenance. Mol. Cell. Biol. 23 (2003) 5572-5580
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5572-5580
-
-
Jaco, I.1
-
56
-
-
11144357186
-
Telomere maintenance requires the RAD51D recombination/repair protein
-
Tarsounas M., et al. Telomere maintenance requires the RAD51D recombination/repair protein. Cell 117 (2004) 337-347
-
(2004)
Cell
, vol.117
, pp. 337-347
-
-
Tarsounas, M.1
-
57
-
-
0029954325
-
TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae
-
Runge K.W., and Zakian V.A. TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Mol. Cell. Biol. 16 (1996) 3094-3105
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3094-3105
-
-
Runge, K.W.1
Zakian, V.A.2
-
58
-
-
37349014081
-
Tel2 regulates the stability of PI3K-related protein kinases
-
Takai H., et al. Tel2 regulates the stability of PI3K-related protein kinases. Cell 131 (2007) 1248-1259
-
(2007)
Cell
, vol.131
, pp. 1248-1259
-
-
Takai, H.1
-
59
-
-
41649120222
-
Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break
-
Anderson C.M., et al. Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break. Genes Dev. 22 (2008) 854-859
-
(2008)
Genes Dev.
, vol.22
, pp. 854-859
-
-
Anderson, C.M.1
-
60
-
-
36749055217
-
Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits
-
Hayashi T., et al. Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits. Genes Cells 12 (2007) 1357-1370
-
(2007)
Genes Cells
, vol.12
, pp. 1357-1370
-
-
Hayashi, T.1
-
61
-
-
0033539171
-
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle
-
Seto A.G., et al. Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature 401 (1999) 177-180
-
(1999)
Nature
, vol.401
, pp. 177-180
-
-
Seto, A.G.1
-
62
-
-
0033598944
-
Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta
-
Diede S.J., and Gottschling D.E. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell 99 (1999) 723-733
-
(1999)
Cell
, vol.99
, pp. 723-733
-
-
Diede, S.J.1
Gottschling, D.E.2
-
63
-
-
0034175814
-
Cell cycle restriction of telomere elongation
-
Marcand S., et al. Cell cycle restriction of telomere elongation. Curr. Biol. 10 (2000) 487-490
-
(2000)
Curr. Biol.
, vol.10
, pp. 487-490
-
-
Marcand, S.1
-
64
-
-
0037047643
-
Est1p as a cell cycle-regulated activator of telomere-bound telomerase
-
Taggart A.K.P., et al. Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 297 (2002) 1023-1026
-
(2002)
Science
, vol.297
, pp. 1023-1026
-
-
Taggart, A.K.P.1
-
65
-
-
33746850081
-
Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae
-
Osterhage J.L., et al. Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae. Nat. Struct. Mol. Biol. 13 (2006) 720-728
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 720-728
-
-
Osterhage, J.L.1
-
66
-
-
0033568014
-
Normal human telomeres are not late replicating
-
Wright W.E., et al. Normal human telomeres are not late replicating. Exp. Cell Res. 251 (1999) 492-499
-
(1999)
Exp. Cell Res.
, vol.251
, pp. 492-499
-
-
Wright, W.E.1
-
67
-
-
4444227318
-
Asynchronous replication timing of telomeres at opposite arms of mammalian chromosomes
-
Zou Y., et al. Asynchronous replication timing of telomeres at opposite arms of mammalian chromosomes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 12928-12933
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 12928-12933
-
-
Zou, Y.1
-
68
-
-
33750801681
-
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
-
Verdun R.E., and Karlseder J. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell 127 (2006) 709-720
-
(2006)
Cell
, vol.127
, pp. 709-720
-
-
Verdun, R.E.1
Karlseder, J.2
-
69
-
-
31944436260
-
Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres
-
Jady B.E., et al. Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres. Mol. Biol. Cell 17 (2006) 944-954
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 944-954
-
-
Jady, B.E.1
-
70
-
-
31944444988
-
Cell cycle-regulated trafficking of human telomerase to telomeres
-
Tomlinson R.L., et al. Cell cycle-regulated trafficking of human telomerase to telomeres. Mol. Biol. Cell 17 (2006) 955-965
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 955-965
-
-
Tomlinson, R.L.1
-
71
-
-
0033564210
-
Progressive cis-inhibition of telomerase upon telomere elongation
-
Marcand S., et al. Progressive cis-inhibition of telomerase upon telomere elongation. EMBO J. 18 (1999) 3509-3519
-
(1999)
EMBO J.
, vol.18
, pp. 3509-3519
-
-
Marcand, S.1
-
72
-
-
2042534735
-
Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states
-
Teixeira M.T., et al. Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states. Cell 117 (2004) 323-335
-
(2004)
Cell
, vol.117
, pp. 323-335
-
-
Teixeira, M.T.1
-
73
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann M.T., et al. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107 (2001) 67-77
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
-
74
-
-
0034616215
-
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
-
Ouellette M.M., et al. Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase. J. Biol. Chem. 275 (2000) 10072-10076
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10072-10076
-
-
Ouellette, M.M.1
-
75
-
-
0034647836
-
Transient expression of human telomerase extends the life span of normal human fibroblasts
-
Steinert S., et al. Transient expression of human telomerase extends the life span of normal human fibroblasts. Biochem. Biophys. Res. Commun. 273 (2000) 1095-1098
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 1095-1098
-
-
Steinert, S.1
-
76
-
-
0037133668
-
Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert
-
Liu Y., et al. Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 3597-3602
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 3597-3602
-
-
Liu, Y.1
-
77
-
-
34547731434
-
Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae
-
Sabourin M., et al. Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol. Cell 27 (2007) 550-561
-
(2007)
Mol. Cell
, vol.27
, pp. 550-561
-
-
Sabourin, M.1
-
78
-
-
34447532519
-
Increased association of telomerase with short telomeres in yeast
-
Bianchi A., and Shore D. Increased association of telomerase with short telomeres in yeast. Genes Dev. 21 (2007) 1726-1730
-
(2007)
Genes Dev.
, vol.21
, pp. 1726-1730
-
-
Bianchi, A.1
Shore, D.2
-
79
-
-
16544390953
-
Cell cycle-dependent regulation of yeast telomerase by Ku
-
Fisher T.S., et al. Cell cycle-dependent regulation of yeast telomerase by Ku. Nat. Struct. Mol. Biol. 11 (2004) 1198-1205
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 1198-1205
-
-
Fisher, T.S.1
-
80
-
-
34547813672
-
S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association
-
Goudsouzian L.K., et al. S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association. Mol. Cell 24 (2006) 603-610
-
(2006)
Mol. Cell
, vol.24
, pp. 603-610
-
-
Goudsouzian, L.K.1
-
81
-
-
35748941663
-
Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast
-
Arneric M., and Lingner J. Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast. EMBO Rep. 8 (2007) 1080-1085
-
(2007)
EMBO Rep.
, vol.8
, pp. 1080-1085
-
-
Arneric, M.1
Lingner, J.2
-
82
-
-
34948898465
-
Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae
-
Chang M., et al. Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae. Genes Dev. 21 (2007) 2485-2494
-
(2007)
Genes Dev.
, vol.21
, pp. 2485-2494
-
-
Chang, M.1
-
83
-
-
34548269900
-
Tel1p preferentially associates with short telomeres to stimulate their elongation
-
Hector R.E., et al. Tel1p preferentially associates with short telomeres to stimulate their elongation. Mol. Cell 27 (2007) 851-858
-
(2007)
Mol. Cell
, vol.27
, pp. 851-858
-
-
Hector, R.E.1
-
84
-
-
20444390159
-
Isolation and characterization of novel xrs2 mutations in Saccharomyces cerevisiae
-
Shima H., et al. Isolation and characterization of novel xrs2 mutations in Saccharomyces cerevisiae. Genetics 170 (2005) 71-85
-
(2005)
Genetics
, vol.170
, pp. 71-85
-
-
Shima, H.1
-
85
-
-
0042379940
-
Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae
-
Mallory J.C., et al. Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae. DNA Repair (Amst.) 2 (2003) 1041-1064
-
(2003)
DNA Repair (Amst.)
, vol.2
, pp. 1041-1064
-
-
Mallory, J.C.1
-
86
-
-
33845669591
-
The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation
-
Tseng S.F., et al. The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation. Nucleic Acids Res. 34 (2006) 6327-6336
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 6327-6336
-
-
Tseng, S.F.1
-
87
-
-
0035830494
-
Cdc13 delivers separate complexes to the telomere for end protection and replication
-
Pennock E., et al. Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell 104 (2001) 387-396
-
(2001)
Cell
, vol.104
, pp. 387-396
-
-
Pennock, E.1
-
88
-
-
4944265507
-
Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1
-
Bianchi A., et al. Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1. Mol. Cell 16 (2004) 139-146
-
(2004)
Mol. Cell
, vol.16
, pp. 139-146
-
-
Bianchi, A.1
-
89
-
-
34547499407
-
Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases
-
Smolka M.B., et al. Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 10364-10369
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 10364-10369
-
-
Smolka, M.B.1
-
90
-
-
33144482714
-
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
-
Feldser D., et al. Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 2249-2251
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 2249-2251
-
-
Feldser, D.1
-
91
-
-
0036670615
-
Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres
-
Nakamura T.M., et al. Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics 161 (2002) 1437-1452
-
(2002)
Genetics
, vol.161
, pp. 1437-1452
-
-
Nakamura, T.M.1
-
92
-
-
27944496124
-
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle
-
Verdun R.E., et al. Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. Mol. Cell 20 (2005) 551-561
-
(2005)
Mol. Cell
, vol.20
, pp. 551-561
-
-
Verdun, R.E.1
-
93
-
-
0041468535
-
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae
-
Viscardi V., et al. Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae. Mol. Biol. Cell 14 (2003) 3126-3143
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3126-3143
-
-
Viscardi, V.1
-
94
-
-
34547794584
-
MRX-dependent DNA damage response to short telomeres
-
Viscardi V., et al. MRX-dependent DNA damage response to short telomeres. Mol. Biol. Cell 18 (2007) 3047-3058
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 3047-3058
-
-
Viscardi, V.1
-
95
-
-
0037115462
-
ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase
-
Shimada K., et al. ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes Dev. 16 (2002) 3236-3252
-
(2002)
Genes Dev.
, vol.16
, pp. 3236-3252
-
-
Shimada, K.1
-
96
-
-
0038730929
-
A central role for DNA replication forks in checkpoint activation and response
-
Tercero J.A., et al. A central role for DNA replication forks in checkpoint activation and response. Mol. Cell 11 (2003) 1323-1336
-
(2003)
Mol. Cell
, vol.11
, pp. 1323-1336
-
-
Tercero, J.A.1
-
97
-
-
10844222498
-
The amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activity
-
Bessler J.B., and Zakian V.A. The amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activity. Genetics 168 (2004) 1205-1218
-
(2004)
Genetics
, vol.168
, pp. 1205-1218
-
-
Bessler, J.B.1
Zakian, V.A.2
-
98
-
-
23044500389
-
POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end
-
Hockemeyer D., et al. POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end. EMBO J. 24 (2005) 2667-2678
-
(2005)
EMBO J.
, vol.24
, pp. 2667-2678
-
-
Hockemeyer, D.1
-
99
-
-
34250348765
-
Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends
-
Hirano Y., and Sugimoto K. Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends. Mol. Biol. Cell 18 (2007) 2026-2036
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2026-2036
-
-
Hirano, Y.1
Sugimoto, K.2
-
100
-
-
27644578165
-
A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint
-
Michelson R.J., et al. A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint. Genes Dev. 19 (2005) 2546-2559
-
(2005)
Genes Dev.
, vol.19
, pp. 2546-2559
-
-
Michelson, R.J.1
-
101
-
-
2942644725
-
The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex
-
Larrivee M., et al. The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex. Genes Dev. 18 (2004) 1391-1396
-
(2004)
Genes Dev.
, vol.18
, pp. 1391-1396
-
-
Larrivee, M.1
-
102
-
-
0033569847
-
G-strand overhangs on telomeres in telomerase-deficient mouse cells
-
Hemann M.T., and Greider C.W. G-strand overhangs on telomeres in telomerase-deficient mouse cells. Nucleic Acids Res. 27 (1999) 3964-3969
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 3964-3969
-
-
Hemann, M.T.1
Greider, C.W.2
-
103
-
-
46049084221
-
A history of telomere biology
-
De Lange T., et al. (Ed), Cold Spring Harbor Laboratory Press
-
Blackburn E.H. A history of telomere biology. In: De Lange T., et al. (Ed). Telomeres. 2nd edn (2006), Cold Spring Harbor Laboratory Press
-
(2006)
Telomeres. 2nd edn
-
-
Blackburn, E.H.1
|