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Volumn 11, Issue 12, 2004, Pages 1198-1205

Cell cycle-dependent regulation of yeast telomerase by Ku

Author keywords

[No Author keywords available]

Indexed keywords

CDC13 PROTEIN, S CEREVISIAE; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; FUNGAL RNA; KU ANTIGEN; RNA; SACCHAROMYCES CEREVISIAE PROTEIN; TELOMERASE; TELOMERASE RNA; TELOMERE BINDING PROTEIN;

EID: 16544390953     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb854     Document Type: Article
Times cited : (180)

References (47)
  • 1
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • Steensel, B., Smogorzewska, A. & de lange, T. TRF2 protects human telomeres from end-to-end fusions. Cell 92, 401-413 (1998).
    • (1998) Cell , vol.92 , pp. 401-413
    • Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 2
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery and chromosome loss
    • Sandell, L.L. & Zakian, V.A. Loss of a yeast telomere: arrest, recovery and chromosome loss. Cell 75, 729-739 (1993).
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 3
    • 0025201982 scopus 로고
    • Position effect at S. Cerevisiae telomeres: Reversible repression of Pol II transcription
    • Gottschling, D.E., Aparicio, O.M., Billington, B.L. & Zakian, V.A. Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63, 751-762 (1990).
    • (1990) Cell , vol.63 , pp. 751-762
    • Gottschling, D.E.1    Aparicio, O.M.2    Billington, B.L.3    Zakian, V.A.4
  • 4
    • 0035874977 scopus 로고    scopus 로고
    • Telomere position effect in human cells
    • Baur, J.A., Zou, Y., Shay, J.W. & Wright, W.E. Telomere position effect in human cells. Science 292, 2075-2077 (2001).
    • (2001) Science , vol.292 , pp. 2075-2077
    • Baur, J.A.1    Zou, Y.2    Shay, J.W.3    Wright, W.E.4
  • 5
    • 0027298574 scopus 로고
    • Origin activation and formation of single-strand TG1_3 tails occur sequentially in late S phase on a yeast linear plasmid
    • Wellinger, R.J., Wolf, A.J. & Zakian, V.A. Origin activation and formation of single-strand TG1_3 tails occur sequentially in late S phase on a yeast linear plasmid. Mol. Cell. Biol. 13, 4057-4065 (1993).
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4057-4065
    • Wellinger, R.J.1    Wolf, A.J.2    Zakian, V.A.3
  • 6
    • 0027509950 scopus 로고
    • Saccharomyces telomeres acquire single- strand TG1_3 tails late in S phase
    • Wellinger, R.J., Wolf, A.J. & Zakian, V. A. Saccharomyces telomeres acquire single- strand TG1_3 tails late in S phase. Cell 72, 51-60 (1993).
    • (1993) Cell , vol.72 , pp. 51-60
    • Wellinger, R.J.1    Wolf, A.J.2    Zakian, V.A.3
  • 7
    • 0034175814 scopus 로고    scopus 로고
    • Cell cycle restriction of telomere elongation
    • Marcand, S., Brevet, V., Mann, C. & Gilson, E. Cell cycle restriction of telomere elongation. Curr. Biol. 10, 487-490 (2000).
    • (2000) Curr. Biol. , vol.10 , pp. 487-490
    • Marcand, S.1    Brevet, V.2    Mann, C.3    Gilson, E.4
  • 8
    • 0032076127 scopus 로고    scopus 로고
    • Yeast Ku as a regulator of chromosomal DNA end structure
    • Gravel, S., Larrivee, M., Labrecque, P. & Wellinger, R.J. Yeast Ku as a regulator of chromosomal DNA end structure. Science 280, 741-744 (1998).
    • (1998) Science , vol.280 , pp. 741-744
    • Gravel, S.1    Larrivee, M.2    Labrecque, P.3    Wellinger, R.J.4
  • 9
    • 0029843408 scopus 로고    scopus 로고
    • Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNA double strand break rejoining and in telomeric maintenance
    • Boulton, S.J. & Jackson, S.P. Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res. 24, 4639-4648 (1996).
    • (1996) Nucleic Acids Res , vol.24 , pp. 4639-4648
    • Boulton, S.J.1    Jackson, S.P.2
  • 10
    • 0029919650 scopus 로고    scopus 로고
    • The DNA-binding protein Hdf1p (A putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae
    • Porter, S.E., Greenwell, P.W., Ritchie, K.B. & Petes, T.D. The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res. 24, 582-585 (1996).
    • (1996) Nucleic Acids Res , vol.24 , pp. 582-585
    • Porter, S.E.1    Greenwell, P.W.2    Ritchie, K.B.3    Petes, T.D.4
  • 11
    • 0032474732 scopus 로고    scopus 로고
    • The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities
    • Polotnianka, R.M., Li, J. & Lustig, A.J. The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities. Curr. Biol. 8, 831-834 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 831-834
    • Polotnianka, R.M.1    Li, J.2    Lustig, A.J.3
  • 12
    • 0032554793 scopus 로고    scopus 로고
    • Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres
    • Laroche, T. et al. Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr. Biol. 8, 653-656 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 653-656
    • Laroche, T.1
  • 13
    • 0037164718 scopus 로고    scopus 로고
    • Live imaging of telomeres: YKu and Sir proteins define redundant telomere-anchoring pathways in yeast
    • Hediger, F., Neumann, F.R., Van Houwe, G., Dubrana, K. & Gasser, S.M. Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr. Biol. 12, 2076-2089 (2002).
    • (2002) Curr. Biol. , vol.12 , pp. 2076-2089
    • Hediger, F.1    Neumann, F.R.2    Van Houwe, G.3    Dubrana, K.4    Gasser, S.M.5
  • 14
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end- joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton, S.J. & Jackson, S.P. Components of the Ku-dependent non-homologous end- joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17, 1819-1828 (1998).
    • (1998) EMBO J , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 15
    • 0032554797 scopus 로고    scopus 로고
    • Telomere maintenance is dependent on activities required for end repair of double-strand breaks
    • Nugent, C.I. et al. Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr. Biol. 8, 657-660 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 657-660
    • Nugent, C.I.1
  • 16
    • 0036682516 scopus 로고    scopus 로고
    • EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants
    • Maringele, L. & Lydall, D. EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev. 16, 1919-1933 (2002).
    • (2002) Genes Dev , vol.16 , pp. 1919-1933
    • Maringele, L.1    Lydall, D.2
  • 17
    • 0036021349 scopus 로고    scopus 로고
    • A quantitative assay for telomere protection in Saccharomyces cerevisiae
    • DuBois, M.L., Haimberger, Z.W., McIntosh, M.W. & Gottschling, D.E. A quantitative assay for telomere protection in Saccharomyces cerevisiae. Genetics 161, 995-1013 (2002).
    • (2002) Genetics , vol.161 , pp. 995-1013
    • Dubois, M.L.1    Haimberger, Z.W.2    McIntosh, M.W.3    Gottschling, D.E.4
  • 18
    • 0036791764 scopus 로고    scopus 로고
    • Ku complex controls the replication time of DNA in telomere regions
    • Cosgrove, A.J., Nieduszynski, C.A. & Donaldson, A.D. Ku complex controls the replication time of DNA in telomere regions. Genes Dev. 16, 2485-2490 (2002).
    • (2002) Genes Dev , vol.16 , pp. 2485-2490
    • Cosgrove, A.J.1    Nieduszynski, C.A.2    Donaldson, A.D.3
  • 19
    • 0033539095 scopus 로고    scopus 로고
    • DNA damage triggers disruption of telomeric silencing and Mec1p- dependent relocation of Sir3p
    • McAinsh, A.D., Scott-Drew, S., Murray, J.A. & Jackson, S.P. DNA damage triggers disruption of telomeric silencing and Mec1p- dependent relocation of Sir3p. Curr. Biol. 9, 963-966 (1999).
    • (1999) Curr. Biol. , vol.9 , pp. 963-966
    • McAinsh, A.D.1    Scott-Drew, S.2    Murray, J.A.3    Jackson, S.P.4
  • 20
    • 0033612287 scopus 로고    scopus 로고
    • Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
    • Martin, S.G., Laroche, T., Suka, N., Grunstein, M. & Gasser, S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97, 621-633 (1999).
    • (1999) Cell , vol.97 , pp. 621-633
    • Martin, S.G.1    Laroche, T.2    Suka, N.3    Grunstein, M.4    Gasser, S.M.5
  • 21
    • 0141525391 scopus 로고    scopus 로고
    • Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
    • Stellwagen, A.E., Haimberger, Z.W., Veatch, J.R. & Gottschling, D.E. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev. 17, 2384-2395 (2003).
    • (2003) Genes Dev , vol.17 , pp. 2384-2395
    • Stellwagen, A.E.1    Haimberger, Z.W.2    Veatch, J.R.3    Gottschling, D.E.4
  • 22
    • 0035158605 scopus 로고    scopus 로고
    • The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku
    • Peterson, S.E. et al. The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku. Nat. Genet. 27, 64-67 (2001).
    • (2001) Nat. Genet. , vol.27 , pp. 64-67
    • Peterson, S.E.1
  • 23
    • 0026571672 scopus 로고
    • A position effect on the time of replication origin activation in yeast
    • Ferguson, B.M. & Fangman, W.L. A position effect on the time of replication origin activation in yeast. Cell 68, 333-339 (1992).
    • (1992) Cell , vol.68 , pp. 333-339
    • Ferguson, B.M.1    Fangman, W.L.2
  • 24
    • 0141868298 scopus 로고    scopus 로고
    • The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini
    • Bertuch, A.A. & Lundblad, V. The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol. Cell. Biol. 23, 8202-8215 (2003).
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8202-8215
    • Bertuch, A.A.1    Lundblad, V.2
  • 25
    • 0036118479 scopus 로고    scopus 로고
    • Essential regions of Saccharomyces cerevisiae telomerase RNA: Separate elements for Est1p and Est2p interaction
    • Livengood, A.J., Zaug, A.J. & Cech, T.R. Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol. Cell. Biol. 22, 2366-2374 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2366-2374
    • Livengood, A.J.1    Zaug, A.J.2    Cech, T.R.3
  • 26
    • 2942644725 scopus 로고    scopus 로고
    • The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex
    • Larrivee, M., LeBel, C. & Wellinger, R.J. The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex. Genes Dev. 18, 1391-1396 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1391-1396
    • Larrivee, M.1    Lebel, C.2    Wellinger, R.J.3
  • 27
    • 0347988057 scopus 로고    scopus 로고
    • RPA regulates telomerase action by providing Est1p access to chromosome ends
    • Schramke, V. et al. RPA regulates telomerase action by providing Est1p access to chromosome ends. Nat. Genet. 36, 46-54 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 46-54
    • Schramke, V.1
  • 28
    • 2042534735 scopus 로고    scopus 로고
    • Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states
    • Teixeira, M.T., Arneric, M., Sperisen, P. & Lingner, J. Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117, 323-335 (2004).
    • (2004) Cell , vol.117 , pp. 323-335
    • Teixeira, M.T.1    Arneric, M.2    Sperisen, P.3    Lingner, J.4
  • 29
    • 0037716757 scopus 로고    scopus 로고
    • Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining
    • Chan, S.W.-L. & Blackburn, E.H. Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining. Mol. Cell 11, 1379-1387 (2003).
    • (2003) Mol. Cell , vol.11 , pp. 1379-1387
    • Chan, S.W.1    Blackburn, E.H.2
  • 30
    • 0030781067 scopus 로고    scopus 로고
    • Functionally interacting telomerase RNAs in the yeast telomerase complex
    • Prescott, J. & Blackburn, E. Functionally interacting telomerase RNAs in the yeast telomerase complex. Genes Dev. 11, 2790-2800 (1997).
    • (1997) Genes Dev , vol.11 , pp. 2790-2800
    • Prescott, J.1    Blackburn, E.2
  • 31
    • 0029033695 scopus 로고
    • An in vitro assay for Saccharomyces telomerase requires EST1
    • Lin, J.-J. & Zakian, V.A. An in vitro assay for Saccharomyces telomerase requires EST1. Cell 81, 1127-1135 (1995).
    • (1995) Cell , vol.81 , pp. 1127-1135
    • Lin, J.-J.1    Zakian, V.A.2
  • 33
    • 0033994222 scopus 로고    scopus 로고
    • The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA
    • Zhou, J., Hidaka, K. & Futcher, B. The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA. Mol. Cell. Biol. 20, 1947-1955 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1947-1955
    • Zhou, J.1    Hidaka, K.2    Futcher, B.3
  • 34
    • 0024973811 scopus 로고
    • A mutant with a defect in telomere elongation leads to senescence in yeast
    • Lundblad, V. & Szostak, J.W. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 57, 633-643 (1989).
    • (1989) Cell , vol.57 , pp. 633-643
    • Lundblad, V.1    Szostak, J.W.2
  • 35
    • 0034661246 scopus 로고    scopus 로고
    • The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase a and the telomerase-associated Est1 protein
    • Qi, H. & Zakian, V.A. The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase a and the telomerase-associated Est1 protein. Genes Dev. 14, 1777-1788 (2000).
    • (2000) Genes Dev , vol.14 , pp. 1777-1788
    • Qi, H.1    Zakian, V.A.2
  • 36
    • 0036861668 scopus 로고    scopus 로고
    • The Est1 subunit of Saccharomyces cerevisiae telom- erase makes multiple contributions to telomere length maintenance
    • Evans, S.K. & Lundblad, V. The Est1 subunit of Saccharomyces cerevisiae telom- erase makes multiple contributions to telomere length maintenance. Genetics 162, 1101-1115 (2002).
    • (2002) Genetics , vol.162 , pp. 1101-1115
    • Evans, S.K.1    Lundblad, V.2
  • 37
    • 0033214013 scopus 로고    scopus 로고
    • Est1 and Cdc13 as comediators of telomerase access
    • Evans, S.K. & Lundblad, V. Est1 and Cdc13 as comediators of telomerase access. Science 286, 117-120 (1999).
    • (1999) Science , vol.286 , pp. 117-120
    • Evans, S.K.1    Lundblad, V.2
  • 38
    • 0035830494 scopus 로고    scopus 로고
    • Cdc13 delivers separate complexes to the telomere for end protection and replication
    • Pennock, E., Buckley, K. & Lundblad, V. Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell 104, 387-396 (2001).
    • (2001) Cell , vol.104 , pp. 387-396
    • Pennock, E.1    Buckley, K.2    Lundblad, V.3
  • 39
    • 0035822641 scopus 로고    scopus 로고
    • Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
    • d'Adda di Fagagna, F. et al. Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Curr. Biol. 11, 1192-1196 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 1192-1196
    • D'adda Di Fagagna, F.1
  • 41
    • 2442688032 scopus 로고    scopus 로고
    • Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86
    • Myung, K. et al. Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86. Mol. Cell. Biol. 24, 5050-5059 (2004).
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 5050-5059
    • Myung, K.1
  • 42
    • 0037033062 scopus 로고    scopus 로고
    • Human Ku70/80 associates physically with telomerase through interaction with hTERT
    • Chai, W., Ford, L.P., Lenertz, L., Wright, W.E. & Shay, J.W. Human Ku70/80 associates physically with telomerase through interaction with hTERT. J. Biol. Chem. 277, 47242-47247 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 47242-47247
    • Chai, W.1    Ford, L.P.2    Lenertz, L.3    Wright, W.E.4    Shay, J.W.5
  • 43
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R.S. & Hieter, P. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-27 (1989).
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 44
    • 0027988467 scopus 로고
    • Transcription of a yeast telomere alleviates telomere position effect without affecting chromosome stability
    • Sandell, L.L., Gottschling, D.E. & Zakian, V.A. Transcription of a yeast telomere alleviates telomere position effect without affecting chromosome stability. Proc. Natl. Acad. Sci. USA 91, 12061-12065 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12061-12065
    • Sandell, L.L.1    Gottschling, D.E.2    Zakian, V.A.3
  • 45
    • 0035806977 scopus 로고    scopus 로고
    • The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres
    • Tsukamoto, Y., Taggart, A.K.P. & Zakian, V.A. The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres. Curr. Biol. 11, 1328-1335 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 1328-1335
    • Tsukamoto, Y.1    Taggart, A.K.P.2    Zakian, V.A.3
  • 46
    • 0029042961 scopus 로고
    • Gene disruption with PCR products in Saccharomyces cerevisiae
    • Lorenz, M.C. et al. Gene disruption with PCR products in Saccharomyces cerevisiae. Gene 158, 113-117 (1995).
    • (1995) Gene , vol.158 , pp. 113-117
    • Lorenz, M.C.1
  • 47
    • 0032699279 scopus 로고    scopus 로고
    • Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants
    • Friedman, K.L. & Cech, T.R. Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants. Genes Dev. 13, 2863-2874 (1999)
    • (1999) Genes Dev , vol.13 , pp. 2863-2874
    • Friedman, K.L.1    Cech, T.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.