Switching human telomerase on and off with hPOT1 protein in vitro

Journal of Biological Chemistry

Volumn 280, Issue 21, 2005, Pages 20449-20456

  Lei, Ming ^a,b   Zaug, Arthur J ^a   Podell, Elaine R ^a   Cech, Thomas R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELLS; CHROMOSOMES; CRYSTAL STRUCTURE; DNA; ENZYME INHIBITION; SUBSTRATES;

HUMAN TELOMERASE; PROTECTION OF TELOMERASE 1 (POT1); TELOMERE; TELOMERIC DNA;

ENZYMES;

BINDING PROTEIN; NUCLEOTIDE; PROTEIN HPOT1; RECOMBINANT ENZYME; SINGLE STRANDED DNA; TELOMERASE; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CHROMOSOME; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME MECHANISM; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; REGULATORY MECHANISM; TELOMERE;

ALTERNATIVE SPLICING; BINDING SITES; CRYSTALLIZATION; DNA; DNA PRIMERS; DNA, SINGLE-STRANDED; ENZYME INHIBITORS; HEMAGGLUTININS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OLIGONUCLEOTIDES; RECOMBINANT PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TELOMERASE; TELOMERE; TELOMERE-BINDING PROTEINS;

EID: 20144382152     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502212200     Document Type: Article

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