On the applicability of GPCR homology models to computer-aided drug discovery: A comparison between in silico and crystal structures of the β2-adrenergic receptor

Journal of Medicinal Chemistry

Volumn 51, Issue 10, 2008, Pages 2907-2914

  Costanzi, Stefano ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CARAZOLOL; G PROTEIN COUPLED RECEPTOR; RHODOPSIN;

ARTICLE; COMPUTER AIDED DESIGN; COMPUTER MODEL; CRYSTAL STRUCTURE; MOLECULAR DOCKING; MOLECULAR MODEL; PROTEIN BINDING; PROTEIN CONFORMATION; RESIDUE ANALYSIS; SEQUENCE HOMOLOGY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; PROPANOLAMINES; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2; RHODOPSIN; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 43949095157     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800044k     Document Type: Article

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