Agonist-induced conformational changes in thyrotropin-releasing hormone receptor type I: Disulfide cross-linking and molecular modeling approaches

Biochemistry

Volumn 44, Issue 7, 2005, Pages 2419-2431

  Huang, Wei ^a,b   Osman, Roman ^c   Gershengorn, Marvin C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CHEMICAL BONDS; COMPUTER SIMULATION; CONFORMATIONS; CROSSLINKING; HYDRATION; MATHEMATICAL MODELS; MOLECULAR DYNAMICS; MUTAGENESIS; SUBSTITUTION REACTIONS;

CYSTEINES; CYTOPLASMIC; THYROTROPIN; TRANSMEMBRANE HELICES;

HORMONES;

CYSTEINE; CYSTINE; DISULFIDE; GLUTAMINE; GLYCINE; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTIRELIN RECEPTOR; PROTIRELIN RECEPTOR 1; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; COMPUTER MODEL; CONFORMATIONAL TRANSITION; CROSS LINKING; DISULFIDE BOND; HUMAN; HUMAN CELL; LIPID BILAYER; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CROSS-LINKING REAGENTS; CYSTEINE; CYTOPLASM; DISULFIDES; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENANTHROLINES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, THYROTROPIN-RELEASING HORMONE; THYROTROPIN-RELEASING HORMONE;

EID: 14044251558     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048808+     Document Type: Article

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