Sequential binding of agonists to the β2 adrenoceptor. Kinetic evidence for intermediate conformational states

Journal of Biological Chemistry

Volumn 279, Issue 1, 2004, Pages 686-691

  Swaminath, Gayathri ^a   Xiang, Yang ^a   Lee, Tae Weon ^a   Steenhuis, Jacqueline ^a   Parnot, Charles ^a   Kobilka, Brian K ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; CONFORMATIONS; FLUORESCENCE; HORMONES; REACTION KINETICS; SPECTROSCOPIC ANALYSIS;

CELLULAR SIGNALLING CASCADES; SEQUENTIAL INTERACTIONS;

PROTEINS;

ADRENALIN; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CATECHOL DERIVATIVE; CATECHOLAMINE; DOPAMINE; G PROTEIN COUPLED RECEPTOR; ISOPRENALINE; NORADRENALIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ASSAY; CORRELATION ANALYSIS; EMBRYO; HUMAN; HUMAN CELL; INSECT CELL; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION;

ADRENERGIC BETA-AGONISTS; ANIMALS; BINDING SITES; CATECHOLS; DOPAMINE; EPINEPHRINE; ISOPROTERENOL; KINETICS; MODELS, MOLECULAR; NOREPINEPHRINE; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2; SPECTROMETRY, FLUORESCENCE; SPODOPTERA; TRANSFECTION;

ANIMALIA; INSECTA;

EID: 0345791508     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310888200     Document Type: Article

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