A monoclonal antibody for G protein-coupled receptor crystallography

Nature Methods

Volumn 4, Issue 11, 2007, Pages 927-929

  Day, Peter W ^a   Rasmussen, Søren G F ^a   Parnot, Charles ^a   Fung, Juan José ^a   Masood, Asna ^b   Kobilka, Tong Sun ^a   Yao, Xiao Jie ^a   Choi, Hee Jung ^a   Weis, William I ^a   Rohrer, Daniel K ^b   Kobilka, Brian K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Medarex Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN F(AB) FRAGMENT; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; RHODOPSIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIFFRACTION; HUMAN; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; BLOTTING, WESTERN; CRYSTALLIZATION; CRYSTALLOGRAPHY; EPITOPES; FLUORESCENT DYES; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT PROTEINS; RHODAMINES; VACCINATION;

MAMMALIA;

EID: 35748947246     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth1112     Document Type: Article

References (10)

1. Li, J., Edwards, P.C., Burghammer, M., Villa, C. & Schertler, G.F. J. Mol. Biol. 343, 1409-1438 (2004).
2. Okada, T. et al. J. Mol. Biol. 342, 571-583 (2004).
3. Palczewski, K. et al. Science 289, 739-745 (2000).
4. Hunte, C. & Michel, H. Curr. Opin. Struct. Biol. 12, 503-508 (2002).
5. Granier, S. et al. J. Biol. Chem. (2007).
6. Kobilka, B.K. et al. Science 238, 650-656 (1987).
7. Mancia, F. et al. Proc. Natl. Acad. Sci. USA 104, 4303-4308 (2007).
8. Swaminath, G. et al. J. Biol. Chem. 279, 696-691 (2004).
9. Yao, X. et al. Nat. Chem. Biol. 2, 417-422 (2006).
10. Rasmussen, S.G.F. et al. Nature (in the press).