Human cytidine deaminase: A three-dimensional homology model of a tetrameric metallo-enzyme inferred from the crystal structure of a distantly related dimeric homologue

Journal of Molecular Graphics and Modelling

Volumn 25, Issue 1, 2006, Pages 10-16

  Costanzi, Stefano ^a   Vincenzetti, Silvia ^b   Cristalli, Gloria ^b   Vita, Alberto ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Cytidine deaminase; Evolution; Homology modeling; Phylogenetic analysis; Sequence alignment

Indexed keywords

CYTIDINE DEAMINASE; EVOLUTION; HOMOLOGY MODELING; PHYLOGENETIC ANALYSIS; SEQUENCE ALIGNMENT;

CRYSTAL STRUCTURE; DIMERS; ESCHERICHIA COLI; MATHEMATICAL MODELS; MONOMERS;

ENZYME KINETICS;

CYTIDINE DEAMINASE; DIMER; METALLOPROTEIN; MONOMER; POLYMER; TETRAMER;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; MOLECULAR EVOLUTION; MOLECULAR MODEL; PHYLOGENY; PREDICTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SPECIES DIFFERENCE; STRUCTURAL HOMOLOGY; THEORETICAL MODEL; VALIDATION PROCESS;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY; CYTIDINE DEAMINASE; DIMERIZATION; ESCHERICHIA COLI; HUMANS; METALLOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN CONFORMATION; STRUCTURAL HOMOLOGY, PROTEIN;

ESCHERICHIA COLI;

EID: 33747877141     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2005.10.008     Document Type: Article

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