A model of inverse agonist action at thyrotropin-releasing hormone receptor type 1: Role of a conserved tryptophan in helix 6

Molecular Pharmacology

Volumn 66, Issue 5, 2004, Pages 1192-1200

  Lu, Xinping ^a   Huang, Wei ^a   Worthington, Sharon ^a   Drabik, Piotr ^b   Osman, Roman ^b   Gershengorn, Marvin C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE RECEPTOR; MIDAZOLAM; TRYPTOPHAN;

ARTICLE; BINDING ASSAY; BINDING SITE; CONFORMATION; DRUG BINDING; DRUG MECHANISM; HUMAN; HUMAN CELL; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; SCREENING; THYROTROPIN RELEASE;

BENZODIAZEPINES; CELLS, CULTURED; HUMANS; MIDAZOLAM; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, THYROTROPIN-RELEASING HORMONE; SIGNAL TRANSDUCTION; THYROTROPIN-RELEASING HORMONE; TRANSFECTION; TRYPTOPHAN;

EID: 6944221315     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.000349     Document Type: Article

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